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The map label for this gene is 52842745

Identifier: 52842745

GI number: 52842745

Start: 2868674

End: 2869693

Strand: Direct

Name: 52842745

Synonym: lpg2537

Alternate gene names: NA

Gene position: 2868674-2869693 (Clockwise)

Preceding gene: 52842744

Following gene: 52842752

Centisome position: 84.43

GC content: 40.59

Gene sequence:

>1020_bases
ATGATCGTCGATTTTGAAACGCACTTCATCACTGAAGCTTGTATTGATTATCTGACTCAACGCCAGGAAGTTCCCAAATT
GGTTCCAGATCTCAATGGAGCTTATACAATGTGTTTTACACCTGATGTTTCCTTATTTCACACAAGTGCATTAATGGAAG
AATTATTAAGTTTAAACGAGCAACGACTGGCAATTATGGACCAAGCAGGGGTGACAATCCAGGTATTAAGTTTGACTACT
ATCAATGGGATTGACTCCTGCCCTGGAGATGAAAACAAAAGCACCGCTTTAGCAAGAGAAGTCAATGACCAGCTTTACTC
TGCCATTCAAAGACATCCTGAACGATTTAAAGGTTTTGCTTCTATATCGCCTTATGACGTCAAAGAAGGTGTAAAAGAAT
TGGAAAGAGCGATATCTCAATTAGGTTTTGTAGGTTGGCTTACACACTCCAATTTTGGCCAGGATAATTACCTGGACGAT
AAAACCTATTGGCCATTGCTGGAAGCCGCGGAAGGTTTAAACATTCCTATCTACCTGCATCCGAATGTACCCATCATGCG
CGAATTCGGTAAATATGGTTTTGCCTTGGGGGGAAGTGCTTTAGGGTTTGAATTTGACACGGCTTTATGTTTGATGCGAA
TGATTCTTGGAGGTGTATTCGATGCGTTTCCCAAATTAAAAATTATGCTGGGACACTTGGGTGAAACCATGCCGTTTTTA
ATGGAGCGTCTCGATCATTTATACCGTATACCAGACTTAAAAGCTTATCGACCTTCTATTCAGCGTATTCCCTCAGAGGT
ATTACGTCAAAATGTTTACATAACCACTAGCGGACGTTTCTTCGTTCCCGCCTTACGTTATGTTCTAGAGGTCATGGGGG
AGGACAGGGTATTGTTTGCCTCCGATTACCCAATGGAATCCTTACTTGACGCTACTCGATTTATTCAAGATTCCGATTTA
TCAAACCAAACGAAGCAAAAAATTTTCTCTATAAATGCCAAGAATTTGAACTTAATATGA

Upstream 100 bases:

>100_bases
CATCAGAACTTTTATAGCCATGTGGCGGTATCTAATCTTCCGGCTATACTTAAGCATATAATTTTCAATCATTTTTCTCA
CGTCTAAAAGGATTACGTTC

Downstream 100 bases:

>100_bases
AGCATCTCTCTTGCATCATATCAGTAAAGAGCTGATTTTCTTGCAGACATTAATTGAGCCAGGCTCAATTAATGTCTTGC
TTTATAGAAATAAAATACGA

Product: 5-carboxyvanillate decarboxylase

Products: NA

Alternate protein names: Amidohydrolase; Amidohydrolase Family Protein; Amidohydrolase/Decarboxylase; Metal-Dependent Hydrolase; 2-Amino-3-Carboxylmuconate-6-Semialdehyde Decarboxylase; 2-Amino-3-Carboxymuconate-6-Semialdehyde Decarboxylase; Hydrolase; O-Pyrocatechuate Decarboxylase; 2-Amino-3-Carboxymuconate 6-Semialdehyde Decarboxylase; 4-Oxalomesaconate Hydratase; Tryptophan 2 3-Dioxygenase; 2 3-Dihydroxybenzoic Acid Decarboxylase; Amidohydrolase Family; 5-Carboxyvanillate Decarboxylase; 2-Amino-3-Carboxymuconate-6- Semialdehyde Decarboxylase; Metal-Dependent Hydrolase Of TIM-Barrel Fold; Metal Dependent Hydrolase; 5-Carboxy-2-Hydroxymuconate-6-Semialdehyde Decarboxylase; Amidohydrolase 2 Family Protein; Decarboxylase

Number of amino acids: Translated: 339; Mature: 339

Protein sequence:

>339_residues
MIVDFETHFITEACIDYLTQRQEVPKLVPDLNGAYTMCFTPDVSLFHTSALMEELLSLNEQRLAIMDQAGVTIQVLSLTT
INGIDSCPGDENKSTALAREVNDQLYSAIQRHPERFKGFASISPYDVKEGVKELERAISQLGFVGWLTHSNFGQDNYLDD
KTYWPLLEAAEGLNIPIYLHPNVPIMREFGKYGFALGGSALGFEFDTALCLMRMILGGVFDAFPKLKIMLGHLGETMPFL
MERLDHLYRIPDLKAYRPSIQRIPSEVLRQNVYITTSGRFFVPALRYVLEVMGEDRVLFASDYPMESLLDATRFIQDSDL
SNQTKQKIFSINAKNLNLI

Sequences:

>Translated_339_residues
MIVDFETHFITEACIDYLTQRQEVPKLVPDLNGAYTMCFTPDVSLFHTSALMEELLSLNEQRLAIMDQAGVTIQVLSLTT
INGIDSCPGDENKSTALAREVNDQLYSAIQRHPERFKGFASISPYDVKEGVKELERAISQLGFVGWLTHSNFGQDNYLDD
KTYWPLLEAAEGLNIPIYLHPNVPIMREFGKYGFALGGSALGFEFDTALCLMRMILGGVFDAFPKLKIMLGHLGETMPFL
MERLDHLYRIPDLKAYRPSIQRIPSEVLRQNVYITTSGRFFVPALRYVLEVMGEDRVLFASDYPMESLLDATRFIQDSDL
SNQTKQKIFSINAKNLNLI
>Mature_339_residues
MIVDFETHFITEACIDYLTQRQEVPKLVPDLNGAYTMCFTPDVSLFHTSALMEELLSLNEQRLAIMDQAGVTIQVLSLTT
INGIDSCPGDENKSTALAREVNDQLYSAIQRHPERFKGFASISPYDVKEGVKELERAISQLGFVGWLTHSNFGQDNYLDD
KTYWPLLEAAEGLNIPIYLHPNVPIMREFGKYGFALGGSALGFEFDTALCLMRMILGGVFDAFPKLKIMLGHLGETMPFL
MERLDHLYRIPDLKAYRPSIQRIPSEVLRQNVYITTSGRFFVPALRYVLEVMGEDRVLFASDYPMESLLDATRFIQDSDL
SNQTKQKIFSINAKNLNLI

Specific function: Unknown

COG id: COG2159

COG function: function code R; Predicted metal-dependent hydrolase of the TIM-barrel fold

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI109715856, Length=285, Percent_Identity=29.1228070175439, Blast_Score=109, Evalue=3e-24,
Organism=Caenorhabditis elegans, GI71995651, Length=277, Percent_Identity=25.9927797833935, Blast_Score=94, Evalue=1e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 38416; Mature: 38416

Theoretical pI: Translated: 4.79; Mature: 4.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIVDFETHFITEACIDYLTQRQEVPKLVPDLNGAYTMCFTPDVSLFHTSALMEELLSLNE
CEEECHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCHHHHHHHHHHHHHHCCCH
QRLAIMDQAGVTIQVLSLTTINGIDSCPGDENKSTALAREVNDQLYSAIQRHPERFKGFA
HHHHHEECCCCEEEEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCHHHHCCCC
SISPYDVKEGVKELERAISQLGFVGWLTHSNFGQDNYLDDKTYWPLLEAAEGLNIPIYLH
CCCCHHHHHHHHHHHHHHHHHCHHHEEECCCCCCCCCCCCCHHHHHHHHHCCCCEEEEEC
PNVPIMREFGKYGFALGGSALGFEFDTALCLMRMILGGVFDAFPKLKIMLGHLGETMPFL
CCCHHHHHHHHHCEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
MERLDHLYRIPDLKAYRPSIQRIPSEVLRQNVYITTSGRFFVPALRYVLEVMGEDRVLFA
HHHHHHHHCCCCCHHCCHHHHHHHHHHHHCCEEEEECCCHHHHHHHHHHHHHCCCCEEEE
SDYPMESLLDATRFIQDSDLSNQTKQKIFSINAKNLNLI
CCCCHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MIVDFETHFITEACIDYLTQRQEVPKLVPDLNGAYTMCFTPDVSLFHTSALMEELLSLNE
CEEECHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCHHHHHHHHHHHHHHCCCH
QRLAIMDQAGVTIQVLSLTTINGIDSCPGDENKSTALAREVNDQLYSAIQRHPERFKGFA
HHHHHEECCCCEEEEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCHHHHCCCC
SISPYDVKEGVKELERAISQLGFVGWLTHSNFGQDNYLDDKTYWPLLEAAEGLNIPIYLH
CCCCHHHHHHHHHHHHHHHHHCHHHEEECCCCCCCCCCCCCHHHHHHHHHCCCCEEEEEC
PNVPIMREFGKYGFALGGSALGFEFDTALCLMRMILGGVFDAFPKLKIMLGHLGETMPFL
CCCHHHHHHHHHCEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
MERLDHLYRIPDLKAYRPSIQRIPSEVLRQNVYITTSGRFFVPALRYVLEVMGEDRVLFA
HHHHHHHHCCCCCHHCCHHHHHHHHHHHHCCEEEEECCCHHHHHHHHHHHHHCCCCEEEE
SDYPMESLLDATRFIQDSDLSNQTKQKIFSINAKNLNLI
CCCCHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA