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The map label for this gene is mdcB

Identifier: 52842639

GI number: 52842639

Start: 2746308

End: 2747150

Strand: Direct

Name: mdcB

Synonym: lpg2430

Alternate gene names: 52842639

Gene position: 2746308-2747150 (Clockwise)

Preceding gene: 52842638

Following gene: 52842640

Centisome position: 80.83

GC content: 38.08

Gene sequence:

>843_bases
ATGCAAATTTTCCAGCACTCCTTGCCTAATCCATACAAAATTGCCAGATATTTTGCAAAAACAGCAGTTCAAGCCCTGTA
TGATGAAGTGGCCTTATATCCAAAACCCGGATTAGTCAGTTTTGTTGATAGTGGGGCACATCAAGATATGAATGGAGCCC
TGTTTTTTCGCAGTCTCTTTGGTTTGCGCCATTATTTTTACCAGGTTGGCCTGCATACTGCCTTGGGATATTCACCTAAA
AATCTGGTAACATTTGGCTTGAATGCCGAAAAAACCATGCTAAAGATTACCGGAGGGATCAATACTCATCGAGGAGCTAT
ATTTGCCCTTGGGATATTATGCACTTCGATTTGCAAATTAAGTGTAAAATATCATGCCTTTTCTATTGAAGATCTGCATT
ATGCGATTATTGATCAATGGGCTCAATACCTGGAAAAGGAACACCAAAACACAGATACCCATGGTACATTAGTAACGAAA
AAATATGCTGTACATGATGCTAAACAAACTGCCATTGAAGGGTATAAACCAGTATTCGATACTTATAATGAATTATTGAA
CATGACTCACGATCAGACATTCTTTGGGTTATTGACATACCAACGTTTATTATTGACCATTGACGACATCAATATCCTTT
ATCGTACCGGTCCCGAGGGATTAGAATTTGCCCGTTATCATGTTCAACAAGGCATATGTCAAAACAATCGGGAAAAATCC
ATACAAAAAGCCATTGAACTGCATCAATTATTTTCCAAAAAAAACATAAGTCCCGGGGGCGTAGCAGATATGTTAGGCTT
AATTTATTTTTTACGGCATGTTTTCTCAAGAGAAGCCAAATGA

Upstream 100 bases:

>100_bases
GGCGACTGTTCATGGGCAGAATTGCTACAAATCCACTCCAGTGATTCTATTTTGTTTAAAACAACAAAAAAAGTAACTTT
AGTGAAAAGAGAGAGCCTAT

Downstream 100 bases:

>100_bases
AAATATTATTTCTTTTTGCCGGTCAAGGTTATCATGCTGACAGTTTGTTTGATATTTTTCGAACTGATAAAAAGACAATG
AACCTTCTAAAGATAATGTC

Product: 2(5'-triphosphoribosyl)-3'-dephosphocoenzyme A synthase CitG, modifier of citrate lyase

Products: NA

Alternate protein names: 2-(5''-triphosphoribosyl)-3'-dephospho-CoA synthase [H]

Number of amino acids: Translated: 280; Mature: 280

Protein sequence:

>280_residues
MQIFQHSLPNPYKIARYFAKTAVQALYDEVALYPKPGLVSFVDSGAHQDMNGALFFRSLFGLRHYFYQVGLHTALGYSPK
NLVTFGLNAEKTMLKITGGINTHRGAIFALGILCTSICKLSVKYHAFSIEDLHYAIIDQWAQYLEKEHQNTDTHGTLVTK
KYAVHDAKQTAIEGYKPVFDTYNELLNMTHDQTFFGLLTYQRLLLTIDDINILYRTGPEGLEFARYHVQQGICQNNREKS
IQKAIELHQLFSKKNISPGGVADMLGLIYFLRHVFSREAK

Sequences:

>Translated_280_residues
MQIFQHSLPNPYKIARYFAKTAVQALYDEVALYPKPGLVSFVDSGAHQDMNGALFFRSLFGLRHYFYQVGLHTALGYSPK
NLVTFGLNAEKTMLKITGGINTHRGAIFALGILCTSICKLSVKYHAFSIEDLHYAIIDQWAQYLEKEHQNTDTHGTLVTK
KYAVHDAKQTAIEGYKPVFDTYNELLNMTHDQTFFGLLTYQRLLLTIDDINILYRTGPEGLEFARYHVQQGICQNNREKS
IQKAIELHQLFSKKNISPGGVADMLGLIYFLRHVFSREAK
>Mature_280_residues
MQIFQHSLPNPYKIARYFAKTAVQALYDEVALYPKPGLVSFVDSGAHQDMNGALFFRSLFGLRHYFYQVGLHTALGYSPK
NLVTFGLNAEKTMLKITGGINTHRGAIFALGILCTSICKLSVKYHAFSIEDLHYAIIDQWAQYLEKEHQNTDTHGTLVTK
KYAVHDAKQTAIEGYKPVFDTYNELLNMTHDQTFFGLLTYQRLLLTIDDINILYRTGPEGLEFARYHVQQGICQNNREKS
IQKAIELHQLFSKKNISPGGVADMLGLIYFLRHVFSREAK

Specific function: Involved in the formation of 2-(5''-phosphoribosyl)-3'- dephosphocoenzyme-A, the prosthetic group of the acyl-carrier protein of the malonate decarboxylase [H]

COG id: COG1767

COG function: function code H; Triphosphoribosyl-dephospho-CoA synthetase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CitG/MdcB family [H]

Homologues:

Organism=Escherichia coli, GI1786830, Length=277, Percent_Identity=27.7978339350181, Blast_Score=89, Evalue=2e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002736
- InterPro:   IPR017555 [H]

Pfam domain/function: PF01874 CitG [H]

EC number: =2.7.8.25 [H]

Molecular weight: Translated: 31920; Mature: 31920

Theoretical pI: Translated: 8.90; Mature: 8.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQIFQHSLPNPYKIARYFAKTAVQALYDEVALYPKPGLVSFVDSGAHQDMNGALFFRSLF
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCCCCCHHHHHHHHH
GLRHYFYQVGLHTALGYSPKNLVTFGLNAEKTMLKITGGINTHRGAIFALGILCTSICKL
HHHHHHHHHHHHHHHCCCCCCEEEECCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHH
SVKYHAFSIEDLHYAIIDQWAQYLEKEHQNTDTHGTLVTKKYAVHDAKQTAIEGYKPVFD
HHHHEEEEHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHHHCCCHHHH
TYNELLNMTHDQTFFGLLTYQRLLLTIDDINILYRTGPEGLEFARYHVQQGICQNNREKS
HHHHHHCCCCCHHHHHHHHHHHHHHHHHCCEEEEECCCCHHHHHHHHHHHHHHCCCHHHH
IQKAIELHQLFSKKNISPGGVADMLGLIYFLRHVFSREAK
HHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MQIFQHSLPNPYKIARYFAKTAVQALYDEVALYPKPGLVSFVDSGAHQDMNGALFFRSLF
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCCCCCHHHHHHHHH
GLRHYFYQVGLHTALGYSPKNLVTFGLNAEKTMLKITGGINTHRGAIFALGILCTSICKL
HHHHHHHHHHHHHHHCCCCCCEEEECCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHH
SVKYHAFSIEDLHYAIIDQWAQYLEKEHQNTDTHGTLVTKKYAVHDAKQTAIEGYKPVFD
HHHHEEEEHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHHHCCCHHHH
TYNELLNMTHDQTFFGLLTYQRLLLTIDDINILYRTGPEGLEFARYHVQQGICQNNREKS
HHHHHHCCCCCHHHHHHHHHHHHHHHHHCCEEEEECCCCHHHHHHHHHHHHHHCCCHHHH
IQKAIELHQLFSKKNISPGGVADMLGLIYFLRHVFSREAK
HHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10561613 [H]