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The map label for this gene is mdcB

Identifier: 52842636

GI number: 52842636

Start: 2743785

End: 2744996

Strand: Direct

Name: mdcB

Synonym: lpg2427

Alternate gene names: 52842636

Gene position: 2743785-2744996 (Clockwise)

Preceding gene: 52842635

Following gene: 52842637

Centisome position: 80.75

GC content: 41.67

Gene sequence:

>1212_bases
TTGGTAGACCTATTTATGGATAAATATCAATACACATTCAGTTTGCCCAAAAAACTCCAAATATCTCCTATGATTAAAGT
TGGAGTGGCCGGTTCAGGTAATTTGGAAGTGATTATTAAACCAAACTCTAACTTTGATAAAACCGATATTATTGTAAATA
CTGTAATCTCTGGTTTCCGAAATACCTGGGATGCAGTGATTGAACGCTTTGTTGAAGACTATCCTTATGGCGGGCTATCC
ATTACTCTTAACGATGCGGGGGCCACTCCGCCTGTCGTTTCCTTACGCCTACGTCAGGCGATGGAAACCTACCAAACAGG
ATATCATAAAAAGGATAGCTACACAGAAGCCGCCGCACGCAATAGAATTTATTCGTTAGTCGATGAAAACAGTTTTACAG
AATTCTTACTCGATAAAGACACACCTAGCCCCACCCTGCCTCAGTTAAACATGCAAGTGGAAACAGACGATGGGGTCATC
ATTGGTATCGCCAAAATGAATGGAATTGATATAGCCATTGCATCGCAACAAAAAGATTTCATTGGCGGCTCAGTAGGAGA
GATACATGGTGCCAAAATCAATGGTCTAATCAAGTATGCAATTAAACATCAACTGCCTGCAATCATTTTTTTGATTGACA
GTGGTGGAGTCCGTTTACAAGAGGCGAACGTAGGTGAAATTGAAATTTCTGAAATCATTCGCTCCATCCTGGATGCTCGC
TCAGCCGGCATTAAAACCATAGGCGTTATTTGTGGCAATAATGGGGCCTTTGGTGGCATGGGGATCATCAGTGGCACTCT
TGATTATCTTATCGTTAATCAAGGAGCACGTATTGGCATATCAGGAGCGGAAGTAATTCAGGCAGTAAAAGGAGTTGAAG
TATTTGATAGCAGTAATCGTCCATTAGTCTGGCGAGTCTATGGTGGTAGAACCCGCTTTCTTAAAGACGATGTTCAAGGA
TATACCACCAATAAAACCATGGATATTCGTCAGGAGATAAAAACTGCCCTTAAAACGCTCGCCACTACCCCGTCCCTTAG
TCTGAATTCTATTCTGGCAGAGCATGAACAACTGCAAAAACGCATTACCTCAGCCAAAAATTGCCGTGAGGAAGGTGAGT
GGTTAAAAAATAACCGACCCGAATTATATCAGCAAGACATATTCAGTGTTTCTGACCAGCAATTCCTGGAATTGACTAAT
AAAGGGAAATAA

Upstream 100 bases:

>100_bases
CATTAAAAGAAGCTGATCGCGATTTACTCGCTGCCAAAAACATCCATGATCTAGTGGAAATTTCGAATGGACTTTATAGT
CCTCCTAACAAATTCAGGAA

Downstream 100 bases:

>100_bases
ATGATGCCCAATGAAAAAATTACTTTAAAACAATTAATCGATCATTGCTTTGACACGACAAAAACAACAATTAAACAGCA
AATTGTTTTTGGAGCCGGAA

Product: malonate decarboxylase subunit beta

Products: NA

Alternate protein names: ACCase subunit beta; Acetyl-CoA carboxylase carboxyltransferase subunit beta [H]

Number of amino acids: Translated: 403; Mature: 403

Protein sequence:

>403_residues
MVDLFMDKYQYTFSLPKKLQISPMIKVGVAGSGNLEVIIKPNSNFDKTDIIVNTVISGFRNTWDAVIERFVEDYPYGGLS
ITLNDAGATPPVVSLRLRQAMETYQTGYHKKDSYTEAAARNRIYSLVDENSFTEFLLDKDTPSPTLPQLNMQVETDDGVI
IGIAKMNGIDIAIASQQKDFIGGSVGEIHGAKINGLIKYAIKHQLPAIIFLIDSGGVRLQEANVGEIEISEIIRSILDAR
SAGIKTIGVICGNNGAFGGMGIISGTLDYLIVNQGARIGISGAEVIQAVKGVEVFDSSNRPLVWRVYGGRTRFLKDDVQG
YTTNKTMDIRQEIKTALKTLATTPSLSLNSILAEHEQLQKRITSAKNCREEGEWLKNNRPELYQQDIFSVSDQQFLELTN
KGK

Sequences:

>Translated_403_residues
MVDLFMDKYQYTFSLPKKLQISPMIKVGVAGSGNLEVIIKPNSNFDKTDIIVNTVISGFRNTWDAVIERFVEDYPYGGLS
ITLNDAGATPPVVSLRLRQAMETYQTGYHKKDSYTEAAARNRIYSLVDENSFTEFLLDKDTPSPTLPQLNMQVETDDGVI
IGIAKMNGIDIAIASQQKDFIGGSVGEIHGAKINGLIKYAIKHQLPAIIFLIDSGGVRLQEANVGEIEISEIIRSILDAR
SAGIKTIGVICGNNGAFGGMGIISGTLDYLIVNQGARIGISGAEVIQAVKGVEVFDSSNRPLVWRVYGGRTRFLKDDVQG
YTTNKTMDIRQEIKTALKTLATTPSLSLNSILAEHEQLQKRITSAKNCREEGEWLKNNRPELYQQDIFSVSDQQFLELTN
KGK
>Mature_403_residues
MVDLFMDKYQYTFSLPKKLQISPMIKVGVAGSGNLEVIIKPNSNFDKTDIIVNTVISGFRNTWDAVIERFVEDYPYGGLS
ITLNDAGATPPVVSLRLRQAMETYQTGYHKKDSYTEAAARNRIYSLVDENSFTEFLLDKDTPSPTLPQLNMQVETDDGVI
IGIAKMNGIDIAIASQQKDFIGGSVGEIHGAKINGLIKYAIKHQLPAIIFLIDSGGVRLQEANVGEIEISEIIRSILDAR
SAGIKTIGVICGNNGAFGGMGIISGTLDYLIVNQGARIGISGAEVIQAVKGVEVFDSSNRPLVWRVYGGRTRFLKDDVQG
YTTNKTMDIRQEIKTALKTLATTPSLSLNSILAEHEQLQKRITSAKNCREEGEWLKNNRPELYQQDIFSVSDQQFLELTN
KGK

Specific function: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA [H

COG id: COG0777

COG function: function code I; Acetyl-CoA carboxylase beta subunit

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AccD/PCCB family [H]

Homologues:

Organism=Escherichia coli, GI1788655, Length=190, Percent_Identity=27.3684210526316, Blast_Score=65, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000438
- InterPro:   IPR000022
- InterPro:   IPR011762 [H]

Pfam domain/function: PF01039 Carboxyl_trans [H]

EC number: =6.4.1.2 [H]

Molecular weight: Translated: 44420; Mature: 44420

Theoretical pI: Translated: 5.83; Mature: 5.83

Prosite motif: PS50980 COA_CT_NTER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVDLFMDKYQYTFSLPKKLQISPMIKVGVAGSGNLEVIIKPNSNFDKTDIIVNTVISGFR
CCCCEECCEEEEECCCCCEEECCEEEEEECCCCCEEEEECCCCCCCHHHHHHHHHHHHHH
NTWDAVIERFVEDYPYGGLSITLNDAGATPPVVSLRLRQAMETYQTGYHKKDSYTEAAAR
HHHHHHHHHHHHHCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHH
NRIYSLVDENSFTEFLLDKDTPSPTLPQLNMQVETDDGVIIGIAKMNGIDIAIASQQKDF
HHHHHHHCCCCCHHHEECCCCCCCCCCCCEEEEECCCCEEEEEEEECCEEEEEECCCCHH
IGGSVGEIHGAKINGLIKYAIKHQLPAIIFLIDSGGVRLQEANVGEIEISEIIRSILDAR
CCCCCCCCCCCHHHHHHHHHHHHCCCEEEEEECCCCEEEEECCCCCEEHHHHHHHHHHHH
SAGIKTIGVICGNNGAFGGMGIISGTLDYLIVNQGARIGISGAEVIQAVKGVEVFDSSNR
CCCCEEEEEEECCCCCCCCCHHHHHCEEEEEECCCCEECCCHHHHHHHHHCCCEECCCCC
PLVWRVYGGRTRFLKDDVQGYTTNKTMDIRQEIKTALKTLATTPSLSLNSILAEHEQLQK
CEEEEEECCCEEEEHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
RITSAKNCREEGEWLKNNRPELYQQDIFSVSDQQFLELTNKGK
HHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHCCCC
>Mature Secondary Structure
MVDLFMDKYQYTFSLPKKLQISPMIKVGVAGSGNLEVIIKPNSNFDKTDIIVNTVISGFR
CCCCEECCEEEEECCCCCEEECCEEEEEECCCCCEEEEECCCCCCCHHHHHHHHHHHHHH
NTWDAVIERFVEDYPYGGLSITLNDAGATPPVVSLRLRQAMETYQTGYHKKDSYTEAAAR
HHHHHHHHHHHHHCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHH
NRIYSLVDENSFTEFLLDKDTPSPTLPQLNMQVETDDGVIIGIAKMNGIDIAIASQQKDF
HHHHHHHCCCCCHHHEECCCCCCCCCCCCEEEEECCCCEEEEEEEECCEEEEEECCCCHH
IGGSVGEIHGAKINGLIKYAIKHQLPAIIFLIDSGGVRLQEANVGEIEISEIIRSILDAR
CCCCCCCCCCCHHHHHHHHHHHHCCCEEEEEECCCCEEEEECCCCCEEHHHHHHHHHHHH
SAGIKTIGVICGNNGAFGGMGIISGTLDYLIVNQGARIGISGAEVIQAVKGVEVFDSSNR
CCCCEEEEEEECCCCCCCCCHHHHHCEEEEEECCCCEECCCHHHHHHHHHCCCEECCCCC
PLVWRVYGGRTRFLKDDVQGYTTNKTMDIRQEIKTALKTLATTPSLSLNSILAEHEQLQK
CEEEEEECCCEEEEHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
RITSAKNCREEGEWLKNNRPELYQQDIFSVSDQQFLELTNKGK
HHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11889109 [H]