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The map label for this gene is leuO [H]

Identifier: 52842585

GI number: 52842585

Start: 2681646

End: 2682563

Strand: Direct

Name: leuO [H]

Synonym: lpg2376

Alternate gene names: 52842585

Gene position: 2681646-2682563 (Clockwise)

Preceding gene: 52842584

Following gene: 52842586

Centisome position: 78.92

GC content: 36.38

Gene sequence:

>918_bases
ATGGATAAACTTAATCTCAATTTACTTCGCGCTCTGTATGCACTATTAACCTGCCGTCATCTAACACTTGCTAGCAAAAA
AATGGGTATAAGCCAATCCTCAATGAGTATTTATTTGAAGCAACTGCGTGAGCATTTCCATGATGATTTGCTTGTACGTG
GCCAAGGCAATATTATGCAATTAACTCCTTTAGCTAACTCGTTGATCGGTAAAGCCCGACAAGCCCTCTCACTGATTGAA
ACACTATTTAATACTATAGAGACCTTTAACCCCTTGATTTCAGAAAGAAGTTTCTCAATTGGCATGACTGATTTAATGTC
TATTTTGTTGACTCCAAGTTTGATTAAACGATTGGAACAAGAGGCTCCAGGAGTCAAGCTAAATATAAAACATCCTAGTT
ATTTAAATACGGTGGAAGTGTTTGAGTCCGGTGATATTGATTTAATGATTGGTATGTTTGAGAGAGTCCCAGAAGGCTTA
AAGCAACAAAAATTGTTTCAAGATGAAGCCGTCATTGTTGGGGGAAACAACCACCCAGGAATCCAAAAAGGGAAAATTTG
CATTGAAGAACTATTTAAGTACCCATTAATTCAATTTTCATTAAGAGAAACTCCTTTTTACAATTATTTCGATCGCTATT
TACGTCAACTGGGTCATGACAAACGAGTTTCTATTAGCTTAGGACAGGGGATCATGCCTTTATTGGTTCTTACTGACTCT
CATTATCTTACATTAAGTATTCGAAAAGTAGCTGAAAAACTTTCCCATTTGATACCATTAAGTATTGCCTCTGTACCCTT
TGAGGTTGACAGTTTTAATTGCTATCAATATTGGCACCAAAAAGATGATGCTGATCCTGGTCATCGTTGGTTACGGGAAA
TGATTCTCAGTATAGCTAAGAAATCTTATCTAAAATAA

Upstream 100 bases:

>100_bases
TATTTGCAAACTGTATCGCTCTCAACTAACCTCAAACAAAAAGCCGTTAAAAATAGAGTCATTTAAAACCTATTAGGGTC
CTATATACGGATGATGTTTT

Downstream 100 bases:

>100_bases
TCAGTTAAAACCCACTCTACGAACTAGCTATAGATTGATATAAAACACATATATTTTAGATAATCACAGAAAAGTCTCTT
TTAATAGACCATGAATCAGG

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 305; Mature: 305

Protein sequence:

>305_residues
MDKLNLNLLRALYALLTCRHLTLASKKMGISQSSMSIYLKQLREHFHDDLLVRGQGNIMQLTPLANSLIGKARQALSLIE
TLFNTIETFNPLISERSFSIGMTDLMSILLTPSLIKRLEQEAPGVKLNIKHPSYLNTVEVFESGDIDLMIGMFERVPEGL
KQQKLFQDEAVIVGGNNHPGIQKGKICIEELFKYPLIQFSLRETPFYNYFDRYLRQLGHDKRVSISLGQGIMPLLVLTDS
HYLTLSIRKVAEKLSHLIPLSIASVPFEVDSFNCYQYWHQKDDADPGHRWLREMILSIAKKSYLK

Sequences:

>Translated_305_residues
MDKLNLNLLRALYALLTCRHLTLASKKMGISQSSMSIYLKQLREHFHDDLLVRGQGNIMQLTPLANSLIGKARQALSLIE
TLFNTIETFNPLISERSFSIGMTDLMSILLTPSLIKRLEQEAPGVKLNIKHPSYLNTVEVFESGDIDLMIGMFERVPEGL
KQQKLFQDEAVIVGGNNHPGIQKGKICIEELFKYPLIQFSLRETPFYNYFDRYLRQLGHDKRVSISLGQGIMPLLVLTDS
HYLTLSIRKVAEKLSHLIPLSIASVPFEVDSFNCYQYWHQKDDADPGHRWLREMILSIAKKSYLK
>Mature_305_residues
MDKLNLNLLRALYALLTCRHLTLASKKMGISQSSMSIYLKQLREHFHDDLLVRGQGNIMQLTPLANSLIGKARQALSLIE
TLFNTIETFNPLISERSFSIGMTDLMSILLTPSLIKRLEQEAPGVKLNIKHPSYLNTVEVFESGDIDLMIGMFERVPEGL
KQQKLFQDEAVIVGGNNHPGIQKGKICIEELFKYPLIQFSLRETPFYNYFDRYLRQLGHDKRVSISLGQGIMPLLVLTDS
HYLTLSIRKVAEKLSHLIPLSIASVPFEVDSFNCYQYWHQKDDADPGHRWLREMILSIAKKSYLK

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI87081684, Length=307, Percent_Identity=29.9674267100977, Blast_Score=125, Evalue=3e-30,

Paralogues:

None

Copy number: 825 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 34908; Mature: 34908

Theoretical pI: Translated: 8.98; Mature: 8.98

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDKLNLNLLRALYALLTCRHLTLASKKMGISQSSMSIYLKQLREHFHDDLLVRGQGNIMQ
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCEEEECCCCEEE
LTPLANSLIGKARQALSLIETLFNTIETFNPLISERSFSIGMTDLMSILLTPSLIKRLEQ
EHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCHHHHHHHHH
EAPGVKLNIKHPSYLNTVEVFESGDIDLMIGMFERVPEGLKQQKLFQDEAVIVGGNNHPG
HCCCEEEEECCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCC
IQKGKICIEELFKYPLIQFSLRETPFYNYFDRYLRQLGHDKRVSISLGQGIMPLLVLTDS
CCHHHHHHHHHHHCCHHEEHHCCCCCHHHHHHHHHHHCCCCEEEEECCCCCEEEEEEECC
HYLTLSIRKVAEKLSHLIPLSIASVPFEVDSFNCYQYWHQKDDADPGHRWLREMILSIAK
CEEEEEHHHHHHHHHHHCCHHHHCCCEECCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHH
KSYLK
HHHCC
>Mature Secondary Structure
MDKLNLNLLRALYALLTCRHLTLASKKMGISQSSMSIYLKQLREHFHDDLLVRGQGNIMQ
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCEEEECCCCEEE
LTPLANSLIGKARQALSLIETLFNTIETFNPLISERSFSIGMTDLMSILLTPSLIKRLEQ
EHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCHHHHHHHHH
EAPGVKLNIKHPSYLNTVEVFESGDIDLMIGMFERVPEGLKQQKLFQDEAVIVGGNNHPG
HCCCEEEEECCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCC
IQKGKICIEELFKYPLIQFSLRETPFYNYFDRYLRQLGHDKRVSISLGQGIMPLLVLTDS
CCHHHHHHHHHHHCCHHEEHHCCCCCHHHHHHHHHHHCCCCEEEEECCCCCEEEEEEECC
HYLTLSIRKVAEKLSHLIPLSIASVPFEVDSFNCYQYWHQKDDADPGHRWLREMILSIAK
CEEEEEHHHHHHHHHHHCCHHHHCCCEECCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHH
KSYLK
HHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3413113; 1630901; 9278503; 3519576 [H]