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The map label for this gene is dagK [H]

Identifier: 52842556

GI number: 52842556

Start: 2650501

End: 2651439

Strand: Reverse

Name: dagK [H]

Synonym: lpg2346

Alternate gene names: 52842556

Gene position: 2651439-2650501 (Counterclockwise)

Preceding gene: 52842557

Following gene: 52842555

Centisome position: 78.04

GC content: 37.59

Gene sequence:

>939_bases
TTGTCGGTTGGCTGCATTAGTATGAGTAAAATTGCTGTAGTGATAAATCCTATAGCAGGCGGCGGTCGCGGAAAAAAAGT
TTGGAAAGTCCTAAAACCCGGGTTACATGCCCTATTCGAACAAACTGTTTACAGAATATCTAACAGGGTTAATGATCTTG
AAGCAATCACAGACGGACTTCTTGCTGAAAACCCTGACAGCCTGTTAATAATCGGTGGAGATGGCACTTTAAATCATGTT
TTGAATGGCTTAATTGAGAAAGATAAATTAAAAAATCCGCAAACAAAAATCGCTTTTTTTAACGCAGGTTGTGGCGGTGA
TTTTACAAGACAATTTCCCCAACAGAAAATGACCGAATTCCTGGATAGATTAAGTCATAACCAATTTATCAAGTGTGATA
TTGGGAAAATTACTCTTGCCAATCAATTGTCGAGGTATTTTATTAATATTGCCAGCTGTGGTCTGTCAGGACATGTGGTT
TTGCGTGTCTCTAAAAGCAAGTGGTTAAAAAAACTGGGCGGTACTCTGAATTACTTGTTGCATGCTTTAACCGGGTTGAT
GACCTATCGTAAAACCAAAGTAAGGGTTCAGATAGACGATGCTCTACCATTTGATAGCTCCATCCTGCTCATGGCCGTCT
GCAGTGGCCAGTATTTTGGCGGAGGTATGCATGTAGCGCCAATGGCAAAAGTGAACGATGGCTTGTTTGATGTGGTTTCT
TTTAATGAATTTTCAAAACTAAATGCACTTTTAAAATTATATAAAATTTATTCAGGAGGGCATTTGTTGGATAATAATGT
CCATTATGTTCAGACTAAAAAAATTAAAATAGAGCCGTTGGAAGAAAGTAAAATAGAAATTGAGGCAGATGGTGAAATTA
TTGGTTGCTTACCGGCACAGTTTGAGTTAATTAAAGAAACTCTTCCTCTTATTATTTAA

Upstream 100 bases:

>100_bases
ATTTGTATGAGCCTCTGAAAATGGCAGGCAAGTTGGTTCATTTAATAGGAGGCGCTTATAAAGCTTTGGAGCTTGACGCA
CGTCATGCTATTGATCAGGC

Downstream 100 bases:

>100_bases
AAATAAAGGTCAAAATAGGGCACTTTCTATAAAATTATTTTTTATCAAGACAGGTTGTTGCCTCAAGACGAGATCACATC
ATTAAGTGCAATAAACAACA

Product: transcriptional regulator

Products: NA

Alternate protein names: DAG kinase; DAGK [H]

Number of amino acids: Translated: 312; Mature: 311

Protein sequence:

>312_residues
MSVGCISMSKIAVVINPIAGGGRGKKVWKVLKPGLHALFEQTVYRISNRVNDLEAITDGLLAENPDSLLIIGGDGTLNHV
LNGLIEKDKLKNPQTKIAFFNAGCGGDFTRQFPQQKMTEFLDRLSHNQFIKCDIGKITLANQLSRYFINIASCGLSGHVV
LRVSKSKWLKKLGGTLNYLLHALTGLMTYRKTKVRVQIDDALPFDSSILLMAVCSGQYFGGGMHVAPMAKVNDGLFDVVS
FNEFSKLNALLKLYKIYSGGHLLDNNVHYVQTKKIKIEPLEESKIEIEADGEIIGCLPAQFELIKETLPLII

Sequences:

>Translated_312_residues
MSVGCISMSKIAVVINPIAGGGRGKKVWKVLKPGLHALFEQTVYRISNRVNDLEAITDGLLAENPDSLLIIGGDGTLNHV
LNGLIEKDKLKNPQTKIAFFNAGCGGDFTRQFPQQKMTEFLDRLSHNQFIKCDIGKITLANQLSRYFINIASCGLSGHVV
LRVSKSKWLKKLGGTLNYLLHALTGLMTYRKTKVRVQIDDALPFDSSILLMAVCSGQYFGGGMHVAPMAKVNDGLFDVVS
FNEFSKLNALLKLYKIYSGGHLLDNNVHYVQTKKIKIEPLEESKIEIEADGEIIGCLPAQFELIKETLPLII
>Mature_311_residues
SVGCISMSKIAVVINPIAGGGRGKKVWKVLKPGLHALFEQTVYRISNRVNDLEAITDGLLAENPDSLLIIGGDGTLNHVL
NGLIEKDKLKNPQTKIAFFNAGCGGDFTRQFPQQKMTEFLDRLSHNQFIKCDIGKITLANQLSRYFINIASCGLSGHVVL
RVSKSKWLKKLGGTLNYLLHALTGLMTYRKTKVRVQIDDALPFDSSILLMAVCSGQYFGGGMHVAPMAKVNDGLFDVVSF
NEFSKLNALLKLYKIYSGGHLLDNNVHYVQTKKIKIEPLEESKIEIEADGEIIGCLPAQFELIKETLPLII

Specific function: Catalyzes the phosphorylation of diacylglycerol (DAG) into phosphatidic acid. Is a key enzyme involved in the production of lipoteichoic acid by reintroducing DAG formed from the breakdown of membrane phospholipids into the phosphatidylglycerol biosynthet

COG id: COG1597

COG function: function code IR; Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 DAGKc domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017438
- InterPro:   IPR005218
- InterPro:   IPR001206 [H]

Pfam domain/function: PF00781 DAGK_cat [H]

EC number: =2.7.1.107 [H]

Molecular weight: Translated: 34421; Mature: 34290

Theoretical pI: Translated: 9.14; Mature: 9.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVGCISMSKIAVVINPIAGGGRGKKVWKVLKPGLHALFEQTVYRISNRVNDLEAITDGL
CCCCCEECCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LAENPDSLLIIGGDGTLNHVLNGLIEKDKLKNPQTKIAFFNAGCGGDFTRQFPQQKMTEF
HCCCCCCEEEECCCCCHHHHHHHHHHHHHCCCCCEEEEEEECCCCCHHHHHCHHHHHHHH
LDRLSHNQFIKCDIGKITLANQLSRYFINIASCGLSGHVVLRVSKSKWLKKLGGTLNYLL
HHHHCCCCEEEEECCCEEHHHHHHHHHHHHHHCCCCCEEEEEECHHHHHHHHCCHHHHHH
HALTGLMTYRKTKVRVQIDDALPFDSSILLMAVCSGQYFGGGMHVAPMAKVNDGLFDVVS
HHHHHHHHHHEEEEEEEECCCCCCCCCEEEEEEECCCCCCCCEEECCHHHCCCCEEEECC
FNEFSKLNALLKLYKIYSGGHLLDNNVHYVQTKKIKIEPLEESKIEIEADGEIIGCLPAQ
CHHHHHHHHHHHHHHHHCCCEEECCCEEEEEEEEEEEEECCCCCEEEEECCCEEEECHHH
FELIKETLPLII
HHHHHHHHCCCC
>Mature Secondary Structure 
SVGCISMSKIAVVINPIAGGGRGKKVWKVLKPGLHALFEQTVYRISNRVNDLEAITDGL
CCCCEECCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LAENPDSLLIIGGDGTLNHVLNGLIEKDKLKNPQTKIAFFNAGCGGDFTRQFPQQKMTEF
HCCCCCCEEEECCCCCHHHHHHHHHHHHHCCCCCEEEEEEECCCCCHHHHHCHHHHHHHH
LDRLSHNQFIKCDIGKITLANQLSRYFINIASCGLSGHVVLRVSKSKWLKKLGGTLNYLL
HHHHCCCCEEEEECCCEEHHHHHHHHHHHHHHCCCCCEEEEEECHHHHHHHHCCHHHHHH
HALTGLMTYRKTKVRVQIDDALPFDSSILLMAVCSGQYFGGGMHVAPMAKVNDGLFDVVS
HHHHHHHHHHEEEEEEEECCCCCCCCCEEEEEEECCCCCCCCEEECCHHHCCCCEEEECC
FNEFSKLNALLKLYKIYSGGHLLDNNVHYVQTKKIKIEPLEESKIEIEADGEIIGCLPAQ
CHHHHHHHHHHHHHHHHCCCEEECCCEEEEEEEEEEEEECCCCCEEEEECCCEEEECHHH
FELIKETLPLII
HHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]