Click here to switch to the map view.

The map label for this gene is gpsA

Identifier: 52842519

GI number: 52842519

Start: 2608741

End: 2609808

Strand: Direct

Name: gpsA

Synonym: lpg2309

Alternate gene names: 52842519

Gene position: 2608741-2609808 (Clockwise)

Preceding gene: 52842518

Following gene: 52842522

Centisome position: 76.78

GC content: 43.63

Gene sequence:

>1068_bases
TTGATGCTTTATATATGCAGCAGCTGGAAGAAAAACAAAAAGCAACTGGAGCTAAAGACGAGACTGTTTCTCACTAAGAT
GAATAAAAAAACCATTGCCATGTTAGGTGCCGGCTCCTGGGGCACTGCTGTCGCAATTCATTTAGCTAAAATAGGGCATA
AAACGCTGCTGTGGAGTCATAATCCACAGCATGTTGCCCTCATGGCTGAACAGCATTCAAATCCAGCTTACCTTCCTGGT
ATACCTTTTCCAGAGAATTTGATTCCTTCTGATAATTTAATTGAATGCGTTCAATCAGCGGATTATGTCATCATAGCAGT
TCCTTCTCATGCCTTTGCGGAAATAATCAATAAAATCCCTAAACCAACCCAAGGATTGGCGTGGCTTACGAAGGGTGTTG
ATCCAGCGAGTCATGAATTATTAAGCCAACTGGTTGCCAGTCGATTTGGGGTTGATTTTCCCATAGCAGTTATTTCAGGC
CCATCGTTTGCCAAAGAAGTGGCTCGCTTCCTGCCTACAGCTCTCACTTTGGCTAGTAACAATACGAACTATCAAAAAAA
AATGCATCAACTATTTCATCACGACAACATTCGTGTCTATTTAAGTGATGATTTAATAGGTGTGCAATTATGTGGCGCTG
TTAAAAATATCCTGGCGATAGCCTGTGGAATCAGTGATGGCTTAGGGTATGGCGCTAATGCCAAGGCAGCGCTTATTACC
CGTGGACTTGCTGAAATGACTCGTTTGGGATTAAGCATGGGAGCACGGCAAGATACTTTTCTAGGCTTGGCTGGTGTAGG
GGACTTGGTATTGACTTGTACAGATGATCAATCGCGCAATCGCCGCTTTGGATTGCTCTTGGGTCGTGAAGTGCCTATTC
CTGAAGCCGAACACCAAATTGGCCAAGTAGTTGAAGGGAAACACAATGCCGCTCAAATTTGCGCTATAGCCAACAAAAAT
AAGGTGGAAATGCCAATTTGTGAGCAAATTAATGCGCTATTGCATGGTATTGTTCATGCCCAAGAGGCCGTGAACAACTT
AATGAGTCGTCCCGCCAAGGAAGAATAA

Upstream 100 bases:

>100_bases
AGCTTTTGCCCCAGCATCCTGTTCCCCTATGCTCGTGAAGCAATTACCTCGCAAGTCATTCGTGGCAGCTTCCCCCAATT
AGTACTCGCACCGATTAATT

Downstream 100 bases:

>100_bases
CCTTTGCCCTTGCAAAGAATCATATTAAATTAGGTTTAGTGCACCAGGACACCAGGACGCAGGTGATACTGGTGGATTGT
CGACATTAACCCATAGCATC

Product: NAD(P)H-dependent glycerol-3-phosphate dehydrogenase

Products: NA

Alternate protein names: NAD(P)H-dependent glycerol-3-phosphate dehydrogenase [H]

Number of amino acids: Translated: 355; Mature: 355

Protein sequence:

>355_residues
MMLYICSSWKKNKKQLELKTRLFLTKMNKKTIAMLGAGSWGTAVAIHLAKIGHKTLLWSHNPQHVALMAEQHSNPAYLPG
IPFPENLIPSDNLIECVQSADYVIIAVPSHAFAEIINKIPKPTQGLAWLTKGVDPASHELLSQLVASRFGVDFPIAVISG
PSFAKEVARFLPTALTLASNNTNYQKKMHQLFHHDNIRVYLSDDLIGVQLCGAVKNILAIACGISDGLGYGANAKAALIT
RGLAEMTRLGLSMGARQDTFLGLAGVGDLVLTCTDDQSRNRRFGLLLGREVPIPEAEHQIGQVVEGKHNAAQICAIANKN
KVEMPICEQINALLHGIVHAQEAVNNLMSRPAKEE

Sequences:

>Translated_355_residues
MMLYICSSWKKNKKQLELKTRLFLTKMNKKTIAMLGAGSWGTAVAIHLAKIGHKTLLWSHNPQHVALMAEQHSNPAYLPG
IPFPENLIPSDNLIECVQSADYVIIAVPSHAFAEIINKIPKPTQGLAWLTKGVDPASHELLSQLVASRFGVDFPIAVISG
PSFAKEVARFLPTALTLASNNTNYQKKMHQLFHHDNIRVYLSDDLIGVQLCGAVKNILAIACGISDGLGYGANAKAALIT
RGLAEMTRLGLSMGARQDTFLGLAGVGDLVLTCTDDQSRNRRFGLLLGREVPIPEAEHQIGQVVEGKHNAAQICAIANKN
KVEMPICEQINALLHGIVHAQEAVNNLMSRPAKEE
>Mature_355_residues
MMLYICSSWKKNKKQLELKTRLFLTKMNKKTIAMLGAGSWGTAVAIHLAKIGHKTLLWSHNPQHVALMAEQHSNPAYLPG
IPFPENLIPSDNLIECVQSADYVIIAVPSHAFAEIINKIPKPTQGLAWLTKGVDPASHELLSQLVASRFGVDFPIAVISG
PSFAKEVARFLPTALTLASNNTNYQKKMHQLFHHDNIRVYLSDDLIGVQLCGAVKNILAIACGISDGLGYGANAKAALIT
RGLAEMTRLGLSMGARQDTFLGLAGVGDLVLTCTDDQSRNRRFGLLLGREVPIPEAEHQIGQVVEGKHNAAQICAIANKN
KVEMPICEQINALLHGIVHAQEAVNNLMSRPAKEE

Specific function: De novo phospholipid biosynthesis; glycerol-3 phosphate formation. [C]

COG id: COG0240

COG function: function code C; Glycerol-3-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI24307999, Length=349, Percent_Identity=31.8051575931232, Blast_Score=145, Evalue=4e-35,
Organism=Homo sapiens, GI33695088, Length=313, Percent_Identity=29.3929712460064, Blast_Score=136, Evalue=3e-32,
Organism=Escherichia coli, GI1790037, Length=335, Percent_Identity=47.1641791044776, Blast_Score=325, Evalue=2e-90,
Organism=Caenorhabditis elegans, GI17507425, Length=355, Percent_Identity=27.3239436619718, Blast_Score=130, Evalue=1e-30,
Organism=Caenorhabditis elegans, GI32564399, Length=357, Percent_Identity=27.7310924369748, Blast_Score=129, Evalue=2e-30,
Organism=Caenorhabditis elegans, GI32564403, Length=366, Percent_Identity=27.0491803278689, Blast_Score=124, Evalue=5e-29,
Organism=Caenorhabditis elegans, GI193210136, Length=363, Percent_Identity=27.2727272727273, Blast_Score=124, Evalue=5e-29,
Organism=Caenorhabditis elegans, GI193210134, Length=346, Percent_Identity=24.8554913294798, Blast_Score=94, Evalue=1e-19,
Organism=Saccharomyces cerevisiae, GI6320181, Length=309, Percent_Identity=27.831715210356, Blast_Score=113, Evalue=5e-26,
Organism=Saccharomyces cerevisiae, GI6324513, Length=358, Percent_Identity=25.9776536312849, Blast_Score=110, Evalue=3e-25,
Organism=Drosophila melanogaster, GI22026922, Length=294, Percent_Identity=27.5510204081633, Blast_Score=121, Evalue=7e-28,
Organism=Drosophila melanogaster, GI17136200, Length=311, Percent_Identity=30.8681672025724, Blast_Score=119, Evalue=2e-27,
Organism=Drosophila melanogaster, GI17136204, Length=311, Percent_Identity=30.8681672025724, Blast_Score=119, Evalue=2e-27,
Organism=Drosophila melanogaster, GI17136202, Length=311, Percent_Identity=30.8681672025724, Blast_Score=119, Evalue=2e-27,
Organism=Drosophila melanogaster, GI45551945, Length=264, Percent_Identity=26.5151515151515, Blast_Score=90, Evalue=3e-18,
Organism=Drosophila melanogaster, GI281362270, Length=264, Percent_Identity=26.5151515151515, Blast_Score=89, Evalue=3e-18,
Organism=Drosophila melanogaster, GI24648969, Length=211, Percent_Identity=27.9620853080569, Blast_Score=85, Evalue=9e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR013328
- InterPro:   IPR006168
- InterPro:   IPR006109
- InterPro:   IPR011128
- InterPro:   IPR016040 [H]

Pfam domain/function: PF07479 NAD_Gly3P_dh_C; PF01210 NAD_Gly3P_dh_N [H]

EC number: =1.1.1.94 [H]

Molecular weight: Translated: 38624; Mature: 38624

Theoretical pI: Translated: 8.67; Mature: 8.67

Prosite motif: PS00957 NAD_G3PDH

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMLYICSSWKKNKKQLELKTRLFLTKMNKKTIAMLGAGSWGTAVAIHLAKIGHKTLLWSH
CEEEEECCCCCCHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHCCEEEEECC
NPQHVALMAEQHSNPAYLPGIPFPENLIPSDNLIECVQSADYVIIAVPSHAFAEIINKIP
CCCEEEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCEEEEEECCHHHHHHHHHCC
KPTQGLAWLTKGVDPASHELLSQLVASRFGVDFPIAVISGPSFAKEVARFLPTALTLASN
CCCCCHHHHHCCCCHHHHHHHHHHHHHHCCCCCCEEEECCCHHHHHHHHHCCHHEEEECC
NTNYQKKMHQLFHHDNIRVYLSDDLIGVQLCGAVKNILAIACGISDGLGYGANAKAALIT
CCHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHH
RGLAEMTRLGLSMGARQDTFLGLAGVGDLVLTCTDDQSRNRRFGLLLGREVPIPEAEHQI
HHHHHHHHHHHHCCCCCCCEEEEECCCCEEEEECCCCCCCCEEEEEECCCCCCCHHHHHH
GQVVEGKHNAAQICAIANKNKVEMPICEQINALLHGIVHAQEAVNNLMSRPAKEE
HHHHCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MMLYICSSWKKNKKQLELKTRLFLTKMNKKTIAMLGAGSWGTAVAIHLAKIGHKTLLWSH
CEEEEECCCCCCHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHCCEEEEECC
NPQHVALMAEQHSNPAYLPGIPFPENLIPSDNLIECVQSADYVIIAVPSHAFAEIINKIP
CCCEEEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCEEEEEECCHHHHHHHHHCC
KPTQGLAWLTKGVDPASHELLSQLVASRFGVDFPIAVISGPSFAKEVARFLPTALTLASN
CCCCCHHHHHCCCCHHHHHHHHHHHHHHCCCCCCEEEECCCHHHHHHHHHCCHHEEEECC
NTNYQKKMHQLFHHDNIRVYLSDDLIGVQLCGAVKNILAIACGISDGLGYGANAKAALIT
CCHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHH
RGLAEMTRLGLSMGARQDTFLGLAGVGDLVLTCTDDQSRNRRFGLLLGREVPIPEAEHQI
HHHHHHHHHHHHCCCCCCCEEEEECCCCEEEEECCCCCCCCEEEEEECCCCCCCHHHHHH
GQVVEGKHNAAQICAIANKNKVEMPICEQINALLHGIVHAQEAVNNLMSRPAKEE
HHHHCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA