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The map label for this gene is ackA2

Identifier: 52842475

GI number: 52842475

Start: 2565057

End: 2566175

Strand: Direct

Name: ackA2

Synonym: lpg2262

Alternate gene names: 52842475

Gene position: 2565057-2566175 (Clockwise)

Preceding gene: 52842474

Following gene: 52842476

Centisome position: 75.49

GC content: 41.64

Gene sequence:

>1119_bases
ATGAGGCATTCTGCACTGTTAATCATCAATTCAGGTTCCTCCAGCGTTAAATTTCAAGTGTTCTCCAATACAGAGACACT
TGATCTTCTCGCCAAAGGCAAGATTATTAATATTGGAGGAGAACCATCTTTTACCGCAGTTAACGAAACATTGGAGCACC
AGAGAACTCTAATCACTTTGGAAAAGGACATGACGTATGAGCAAGCCATTCATCTTATACTGGACTGGATTAGCCAACAA
CAGCAAAGCTGGGAAATTCATGCTGTCGCCCATCGGGTCGTTCATGGCGGAGAATATTTCACTCAAAGTGTCCTGGTTAC
TCCGCAAATCATCAGCCAATTGGAAACACTGAATTCTCTCGCGCCCCTACACCAGCCTCATAATTTGGCTGCCATAAAAA
TCATTGGTCGGATTAAGCCAGAATTACCTCAGATTGCATGCTTTGATACCGCCTTTCATGCTCAACATACTCCATTATTT
ACTACTTGTGCTTTGCCCGAATATTTAAGACAACAAGGGATTAGGCGTTATGGATTTCATGGCCTTTCCTATGAATGGAT
TTCTCTCGTTCTCAAAAAAGACTACCCTGATTTGGCTAACAATCGAATTATTATTGCCCATTTAGGCAACGGCGCTAGCT
TGTGCGCTATAAATAGGGGAATCAGTATAGACACCACCATGAGTTTGACAGCGCTGGATGGTTTACCAATGGGAACTCGT
TGTGGCAGTTTGGATCCTGGGGCTGTTATTTACATGATGAGAGAATTGAATCTTCCACCAGATAAGGTAGAGGAAATACT
TTATAACGAATCCGGCTTGCTTGGTTTATCAGGAAAAACCAATAATGTGCTGGAATTACAATCCAGCCCTGATAAAAACG
CTCAATTTGCTTTGGAGTATTTTTGCCTGAAAACAGCTCAATTTATTGGAATGATGGCCATTTCACTAGGTGGAGTAGAT
GGTATTGTATTCACAGGAGGAATAGGGGAAAATTCAGAACCGATTAGAGCAAATATCCTTAAGAGGATAGAGTGCTTACA
CCCTTTTTCTGTTATCGTTATTCCTGCGAATGAAGAAAAAATGATGGCTATGCATACCTTGACAGCCCTCAGGACGTAA

Upstream 100 bases:

>100_bases
CTATCATTCTAGCCAGCAGAGCTGATTCATTACGAACACGTTTATTGTCCTGTGCGGTAGCAACTAAGATAGCAGCGGCT
CGTAAAGCAGGCAAAATAAA

Downstream 100 bases:

>100_bases
AGGCGTATTGTTTACTGGCATAGGTAATGAGTATAAAAAATGGATAAAGACTACTATAAAATCATGGGAGTCAGTCAGGA
TGCTTCTGAAAAAGACATCA

Product: acetate kinase

Products: NA

Alternate protein names: Acetokinase [H]

Number of amino acids: Translated: 372; Mature: 372

Protein sequence:

>372_residues
MRHSALLIINSGSSSVKFQVFSNTETLDLLAKGKIINIGGEPSFTAVNETLEHQRTLITLEKDMTYEQAIHLILDWISQQ
QQSWEIHAVAHRVVHGGEYFTQSVLVTPQIISQLETLNSLAPLHQPHNLAAIKIIGRIKPELPQIACFDTAFHAQHTPLF
TTCALPEYLRQQGIRRYGFHGLSYEWISLVLKKDYPDLANNRIIIAHLGNGASLCAINRGISIDTTMSLTALDGLPMGTR
CGSLDPGAVIYMMRELNLPPDKVEEILYNESGLLGLSGKTNNVLELQSSPDKNAQFALEYFCLKTAQFIGMMAISLGGVD
GIVFTGGIGENSEPIRANILKRIECLHPFSVIVIPANEEKMMAMHTLTALRT

Sequences:

>Translated_372_residues
MRHSALLIINSGSSSVKFQVFSNTETLDLLAKGKIINIGGEPSFTAVNETLEHQRTLITLEKDMTYEQAIHLILDWISQQ
QQSWEIHAVAHRVVHGGEYFTQSVLVTPQIISQLETLNSLAPLHQPHNLAAIKIIGRIKPELPQIACFDTAFHAQHTPLF
TTCALPEYLRQQGIRRYGFHGLSYEWISLVLKKDYPDLANNRIIIAHLGNGASLCAINRGISIDTTMSLTALDGLPMGTR
CGSLDPGAVIYMMRELNLPPDKVEEILYNESGLLGLSGKTNNVLELQSSPDKNAQFALEYFCLKTAQFIGMMAISLGGVD
GIVFTGGIGENSEPIRANILKRIECLHPFSVIVIPANEEKMMAMHTLTALRT
>Mature_372_residues
MRHSALLIINSGSSSVKFQVFSNTETLDLLAKGKIINIGGEPSFTAVNETLEHQRTLITLEKDMTYEQAIHLILDWISQQ
QQSWEIHAVAHRVVHGGEYFTQSVLVTPQIISQLETLNSLAPLHQPHNLAAIKIIGRIKPELPQIACFDTAFHAQHTPLF
TTCALPEYLRQQGIRRYGFHGLSYEWISLVLKKDYPDLANNRIIIAHLGNGASLCAINRGISIDTTMSLTALDGLPMGTR
CGSLDPGAVIYMMRELNLPPDKVEEILYNESGLLGLSGKTNNVLELQSSPDKNAQFALEYFCLKTAQFIGMMAISLGGVD
GIVFTGGIGENSEPIRANILKRIECLHPFSVIVIPANEEKMMAMHTLTALRT

Specific function: Anaerobic degradation of L-threonine to propionate. [C]

COG id: COG0282

COG function: function code C; Acetate kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acetokinase family [H]

Homologues:

Organism=Escherichia coli, GI145693184, Length=400, Percent_Identity=35, Blast_Score=222, Evalue=3e-59,
Organism=Escherichia coli, GI1788633, Length=410, Percent_Identity=32.4390243902439, Blast_Score=189, Evalue=4e-49,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000890
- InterPro:   IPR004372 [H]

Pfam domain/function: PF00871 Acetate_kinase [H]

EC number: =2.7.2.1 [H]

Molecular weight: Translated: 41099; Mature: 41099

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: PS01075 ACETATE_KINASE_1 ; PS01076 ACETATE_KINASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRHSALLIINSGSSSVKFQVFSNTETLDLLAKGKIINIGGEPSFTAVNETLEHQRTLITL
CCCEEEEEEECCCCEEEEEEECCCCEEEEEECCCEEEECCCCCHHHHHHHHHCCEEEEEE
EKDMTYEQAIHLILDWISQQQQSWEIHAVAHRVVHGGEYFTQSVLVTPQIISQLETLNSL
ECCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCHHHHHEEEECHHHHHHHHHHHHH
APLHQPHNLAAIKIIGRIKPELPQIACFDTAFHAQHTPLFTTCALPEYLRQQGIRRYGFH
CCCCCCCCEEEEEEEECCCCCCCCEEEECHHHCCCCCCEEEECCCHHHHHHCCHHHHCCC
GLSYEWISLVLKKDYPDLANNRIIIAHLGNGASLCAINRGISIDTTMSLTALDGLPMGTR
CCCHHHHHHHHHCCCCCCCCCEEEEEECCCCCEEEEEECCCEECCEEEEEEECCCCCCCC
CGSLDPGAVIYMMRELNLPPDKVEEILYNESGLLGLSGKTNNVLELQSSPDKNAQFALEY
CCCCCCCCEEEEEHHCCCCHHHHHHHHHCCCCEEEECCCCCCEEEECCCCCCCHHHHHHH
FCLKTAQFIGMMAISLGGVDGIVFTGGIGENSEPIRANILKRIECLHPFSVIVIPANEEK
HHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCHHHHHHHHHHHCCCEEEEEEECCCCH
MMAMHTLTALRT
HHHHHHHHHHCC
>Mature Secondary Structure
MRHSALLIINSGSSSVKFQVFSNTETLDLLAKGKIINIGGEPSFTAVNETLEHQRTLITL
CCCEEEEEEECCCCEEEEEEECCCCEEEEEECCCEEEECCCCCHHHHHHHHHCCEEEEEE
EKDMTYEQAIHLILDWISQQQQSWEIHAVAHRVVHGGEYFTQSVLVTPQIISQLETLNSL
ECCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCHHHHHEEEECHHHHHHHHHHHHH
APLHQPHNLAAIKIIGRIKPELPQIACFDTAFHAQHTPLFTTCALPEYLRQQGIRRYGFH
CCCCCCCCEEEEEEEECCCCCCCCEEEECHHHCCCCCCEEEECCCHHHHHHCCHHHHCCC
GLSYEWISLVLKKDYPDLANNRIIIAHLGNGASLCAINRGISIDTTMSLTALDGLPMGTR
CCCHHHHHHHHHCCCCCCCCCEEEEEECCCCCEEEEEECCCEECCEEEEEEECCCCCCCC
CGSLDPGAVIYMMRELNLPPDKVEEILYNESGLLGLSGKTNNVLELQSSPDKNAQFALEY
CCCCCCCCEEEEEHHCCCCHHHHHHHHHCCCCEEEECCCCCCEEEECCCCCCCHHHHHHH
FCLKTAQFIGMMAISLGGVDGIVFTGGIGENSEPIRANILKRIECLHPFSVIVIPANEEK
HHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCHHHHHHHHHHHCCCEEEEEEECCCCH
MMAMHTLTALRT
HHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11481431 [H]