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The map label for this gene is glnA [H]

Identifier: 52842465

GI number: 52842465

Start: 2554927

End: 2556300

Strand: Reverse

Name: glnA [H]

Synonym: lpg2252

Alternate gene names: 52842465

Gene position: 2556300-2554927 (Counterclockwise)

Preceding gene: 52842466

Following gene: 52842464

Centisome position: 75.23

GC content: 42.21

Gene sequence:

>1374_bases
ATGCTAAACCCAAGAGAGATCCGAACCATAGAAGATGCAAAACGCATCGTGGAAGAAAGACAATTAACTCATGTTAAGGT
TGGTCTTTTTGATATCGATGGTGTGATGCTGGGCAAGTACATGAGCCGTAACAAGTTTTTTTCGGCTTTGGAGCATGGTT
TTGCTTTTTGTGATGTCATTTTAGGATGGGATTCTAAAGATAAGCTTTATGATAATGTGAAATATACGGGTTGGCATACG
GGTTACCCTGACGCCTCAGTGCGAATTGTTCCTTCAACCTGTCGTGAAATACTATTTGAAGAAAATCAACTGTTGTTTAT
GGCTGAATTTTCACAAGCAGCAGAAGCCATCTGTCCTCGCGGGATCTTGCGTCGTGTAATCAATAAAGCTGCGGGTATGG
GGTATGATGTTTATGCCGCATTGGAATATGAATTTTTTGTATTTGATGAAACACCTGACAGCGTGCGTGCAAAAGGATTT
CGTAATCTAAAGCCTGTTACTCCTGATAATTTTGGCTACTCAATTATTCGTAATACGGTACATGCTGAATTTTATCATCA
AATTCTCACTATGGCGGAAAAAATGGATTTCCCCATTGAAGGTTTACATACTGAAACAGGCCCGGGAGTTCTGGAAGCAG
CAATAGCGGTTGATGATGCCGAGGCCGCAGGAGATAAAGCGGCTTTGTTTAAAACATTTATGAAAATTCTCGCGCAACGC
AATAATAAAATGGCAACTTTTATGGCTAAATGGTCAGGTGATTACCCTGGGCAAAGTGGTCATATTCATCTGTCTTTGCG
AGATAGAGATGGTGGCAAGTCTGCTTTTTATGAATCAGGCAGAGAATATAATATGAGCAAAATTCAACGCCATTTTTTAG
CCGGGCAGCAAAAGTTGATGCCTGAATTTTTAGCCATGTTATCCCCGACTGTGAATAGCTATTCCAGACTAATTCCCGGC
TATTGGGCTCCAACAGAGGCAACATGGGGTGTCGAGAACCGCACCACTGCTTTACGAGTGATTCCCGGCAGTGATAAGTC
ACAGCGTATTGAATATCGCTTGGGTTCTGCAGATGCGAACCCATATCTGGCGTTGGCTGCTGCCATAGGGTCGGGTTTAT
ATGGCATTGAGAATGAGTTGGAGCCTGAGGCTGAGGTAAAAGGGAATTCCTACGAGCAACATCATAGTCCGGCATTGGCG
TTGCCTCGCACATTATGGGAATCGGCACAAAATTTAAAAAACTCTTCCGCTGCTTACGAATTATTTGGTCAAGAATTTGT
TGAGCATTTTGCTGCTTCAAGAGAATGGGAAGAGAGAGAGTTTAGAAAACATATTACTGATTGGGAACTCGACAGGTATT
TTGAAATTATTTAA

Upstream 100 bases:

>100_bases
CTGGATTCAAAATGGGTTATTATCTCAGTGTCGTATTCGTCGCAATTAGACATTGGGAGGTAAAGAAGCTTACATTGACA
GAACGACATAAGGATATGCC

Downstream 100 bases:

>100_bases
TTGAAACGACAGATTTTATAAAATTTATGGATTAAAAATGATTGCTACCTTAAAAACCTATTCTCCTGTCGATAACTCTC
TTTATGTTGAGAGAGAGTAT

Product: glutamine synthetase

Products: NA

Alternate protein names: GS; Glutamate--ammonia ligase [H]

Number of amino acids: Translated: 457; Mature: 457

Protein sequence:

>457_residues
MLNPREIRTIEDAKRIVEERQLTHVKVGLFDIDGVMLGKYMSRNKFFSALEHGFAFCDVILGWDSKDKLYDNVKYTGWHT
GYPDASVRIVPSTCREILFEENQLLFMAEFSQAAEAICPRGILRRVINKAAGMGYDVYAALEYEFFVFDETPDSVRAKGF
RNLKPVTPDNFGYSIIRNTVHAEFYHQILTMAEKMDFPIEGLHTETGPGVLEAAIAVDDAEAAGDKAALFKTFMKILAQR
NNKMATFMAKWSGDYPGQSGHIHLSLRDRDGGKSAFYESGREYNMSKIQRHFLAGQQKLMPEFLAMLSPTVNSYSRLIPG
YWAPTEATWGVENRTTALRVIPGSDKSQRIEYRLGSADANPYLALAAAIGSGLYGIENELEPEAEVKGNSYEQHHSPALA
LPRTLWESAQNLKNSSAAYELFGQEFVEHFAASREWEEREFRKHITDWELDRYFEII

Sequences:

>Translated_457_residues
MLNPREIRTIEDAKRIVEERQLTHVKVGLFDIDGVMLGKYMSRNKFFSALEHGFAFCDVILGWDSKDKLYDNVKYTGWHT
GYPDASVRIVPSTCREILFEENQLLFMAEFSQAAEAICPRGILRRVINKAAGMGYDVYAALEYEFFVFDETPDSVRAKGF
RNLKPVTPDNFGYSIIRNTVHAEFYHQILTMAEKMDFPIEGLHTETGPGVLEAAIAVDDAEAAGDKAALFKTFMKILAQR
NNKMATFMAKWSGDYPGQSGHIHLSLRDRDGGKSAFYESGREYNMSKIQRHFLAGQQKLMPEFLAMLSPTVNSYSRLIPG
YWAPTEATWGVENRTTALRVIPGSDKSQRIEYRLGSADANPYLALAAAIGSGLYGIENELEPEAEVKGNSYEQHHSPALA
LPRTLWESAQNLKNSSAAYELFGQEFVEHFAASREWEEREFRKHITDWELDRYFEII
>Mature_457_residues
MLNPREIRTIEDAKRIVEERQLTHVKVGLFDIDGVMLGKYMSRNKFFSALEHGFAFCDVILGWDSKDKLYDNVKYTGWHT
GYPDASVRIVPSTCREILFEENQLLFMAEFSQAAEAICPRGILRRVINKAAGMGYDVYAALEYEFFVFDETPDSVRAKGF
RNLKPVTPDNFGYSIIRNTVHAEFYHQILTMAEKMDFPIEGLHTETGPGVLEAAIAVDDAEAAGDKAALFKTFMKILAQR
NNKMATFMAKWSGDYPGQSGHIHLSLRDRDGGKSAFYESGREYNMSKIQRHFLAGQQKLMPEFLAMLSPTVNSYSRLIPG
YWAPTEATWGVENRTTALRVIPGSDKSQRIEYRLGSADANPYLALAAAIGSGLYGIENELEPEAEVKGNSYEQHHSPALA
LPRTLWESAQNLKNSSAAYELFGQEFVEHFAASREWEEREFRKHITDWELDRYFEII

Specific function: Unknown

COG id: COG0174

COG function: function code E; Glutamine synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glutamine synthetase family [H]

Homologues:

Organism=Homo sapiens, GI221307485, Length=453, Percent_Identity=22.2958057395143, Blast_Score=97, Evalue=2e-20,
Organism=Escherichia coli, GI87081870, Length=454, Percent_Identity=29.9559471365639, Blast_Score=178, Evalue=5e-46,
Organism=Escherichia coli, GI1790301, Length=428, Percent_Identity=24.2990654205607, Blast_Score=107, Evalue=1e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008147
- InterPro:   IPR014746
- InterPro:   IPR008146
- InterPro:   IPR004809 [H]

Pfam domain/function: PF00120 Gln-synt_C; PF03951 Gln-synt_N [H]

EC number: =6.3.1.2 [H]

Molecular weight: Translated: 51902; Mature: 51902

Theoretical pI: Translated: 5.64; Mature: 5.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLNPREIRTIEDAKRIVEERQLTHVKVGLFDIDGVMLGKYMSRNKFFSALEHGFAFCDVI
CCCCHHHHHHHHHHHHHHHHHHHEEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHEEHHH
LGWDSKDKLYDNVKYTGWHTGYPDASVRIVPSTCREILFEENQLLFMAEFSQAAEAICPR
CCCCCCHHHHCCCEECCEECCCCCCEEEECHHHHHHHHHCCCCEEEEEHHHHHHHHHCHH
GILRRVINKAAGMGYDVYAALEYEFFVFDETPDSVRAKGFRNLKPVTPDNFGYSIIRNTV
HHHHHHHHHHCCCCEEEEEEEEEEEEEECCCCCHHHHCCCCCCCCCCCCCCCHHHHHHHH
HAEFYHQILTMAEKMDFPIEGLHTETGPGVLEAAIAVDDAEAAGDKAALFKTFMKILAQR
HHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHEECCHHHCCCHHHHHHHHHHHHHHC
NNKMATFMAKWSGDYPGQSGHIHLSLRDRDGGKSAFYESGREYNMSKIQRHFLAGQQKLM
CCCEEEEEEECCCCCCCCCCEEEEEEECCCCCCHHHHHCCCCCCHHHHHHHHHHCHHHHH
PEFLAMLSPTVNSYSRLIPGYWAPTEATWGVENRTTALRVIPGSDKSQRIEYRLGSADAN
HHHHHHHCCCHHHHHHHCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCEEEEEECCCCCC
PYLALAAAIGSGLYGIENELEPEAEVKGNSYEQHHSPALALPRTLWESAQNLKNSSAAYE
HHHHHHHHHCCCCCCCCCCCCCCHHCCCCCCHHHCCCHHHHHHHHHHHHHHHCCCHHHHH
LFGQEFVEHFAASREWEEREFRKHITDWELDRYFEII
HHHHHHHHHHHHCCCHHHHHHHHHCCCCCHHHHHCCC
>Mature Secondary Structure
MLNPREIRTIEDAKRIVEERQLTHVKVGLFDIDGVMLGKYMSRNKFFSALEHGFAFCDVI
CCCCHHHHHHHHHHHHHHHHHHHEEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHEEHHH
LGWDSKDKLYDNVKYTGWHTGYPDASVRIVPSTCREILFEENQLLFMAEFSQAAEAICPR
CCCCCCHHHHCCCEECCEECCCCCCEEEECHHHHHHHHHCCCCEEEEEHHHHHHHHHCHH
GILRRVINKAAGMGYDVYAALEYEFFVFDETPDSVRAKGFRNLKPVTPDNFGYSIIRNTV
HHHHHHHHHHCCCCEEEEEEEEEEEEEECCCCCHHHHCCCCCCCCCCCCCCCHHHHHHHH
HAEFYHQILTMAEKMDFPIEGLHTETGPGVLEAAIAVDDAEAAGDKAALFKTFMKILAQR
HHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHEECCHHHCCCHHHHHHHHHHHHHHC
NNKMATFMAKWSGDYPGQSGHIHLSLRDRDGGKSAFYESGREYNMSKIQRHFLAGQQKLM
CCCEEEEEEECCCCCCCCCCEEEEEEECCCCCCHHHHHCCCCCCHHHHHHHHHHCHHHHH
PEFLAMLSPTVNSYSRLIPGYWAPTEATWGVENRTTALRVIPGSDKSQRIEYRLGSADAN
HHHHHHHCCCHHHHHHHCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCEEEEEECCCCCC
PYLALAAAIGSGLYGIENELEPEAEVKGNSYEQHHSPALALPRTLWESAQNLKNSSAAYE
HHHHHHHHHCCCCCCCCCCCCCCHHCCCCCCHHHCCCHHHHHHHHHHHHHHHCCCHHHHH
LFGQEFVEHFAASREWEEREFRKHITDWELDRYFEII
HHHHHHHHHHHHCCCHHHHHHHHHCCCCCHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11016950 [H]