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The map label for this gene is rtcB [C]

Identifier: 52842414

GI number: 52842414

Start: 2483299

End: 2484732

Strand: Reverse

Name: rtcB [C]

Synonym: lpg2201

Alternate gene names: 52842414

Gene position: 2484732-2483299 (Counterclockwise)

Preceding gene: 52842415

Following gene: 52842413

Centisome position: 73.13

GC content: 42.96

Gene sequence:

>1434_bases
GTGATGGATTTAAGTCTTTTGAAAAAAATAAATGATTTTGAATGGCAAATACCGCAACATGGAAAGATGTTGGTGCCAGG
AGTTATTTTCGCTTCAGAACAGCTGATTCTTGATATGGATATGAAAGTTTACGAACAATTATCTAATGTTGCTACTTTGC
CGGGAATTGTTTCTGCTGCTTATGCTATGCCTGATGCGCATTGGGGATATGGTTTTCCGATTGGCGGTGTCGCTGCTTTT
GATCCGGATGATGGAGGGGTTATTTCAGCAGGTGGCGTGGGTTTTGATATTTCATGCGGAGTGAGGCTCTTATCTACTGG
ATTGAAGCGAGATGAATTGGAGTCTGTCAAAGTTAGCCTTGCAGACGCTTTATTTACTCATATTCCAGCTGGAGTAGGTA
GTAGAGGCGGCATTCATTTAACTATCAAACAGCTCGATGATATGATGCGAGGGGGTGCACAGTGGGCAGTAAAACAAGGC
TATGGTGAAGCTGCTGATTTAGAGCGTATCGAGGATCGCGGTTGTGTGGAAGGAGCTATCCCTGATTTTGTCTCTGAGCA
AGCTAAAAAGCGCCAGAAAAATGAAATGGGTACCTTGGGTTCAGGTAATCATTATCTGGAAGTGCAGGAAGTCAGGCAAA
TCTACTGTTCCGATACAGCAACAGCTTTAAATTTGCATGAAGGAGATATTGTAGTGAGTATCCATTGTGGTTCCAGAGGA
TTGGGGCATCAAATTGGTACAGATTACCTCCGTTCCATGGTTATTGAATCACAACATTATGGTATCAAGCTGGCGGATAG
GGAATTGGCTTGTGCTCCTATTCATTCAAAGCTAGGGGAAAATTACCTGGGCGCTATGAGAGCAGGAATTAATTGTGCTT
TAGCCAACAGAGAAATCATCACTCATTTTATGCGCAATGTGTTTCAGGATATTTTACCCCGCACTCAGATTGATCTAATC
TATGACGTTTCTCACAATACTTGTAAAGAAGAATTTCATGAGGTAGATGGCAAGAAAAAGCGCTTATTTGTTCATCGAAA
AGGAGCAACTCGTGCCTTGGGCCCAGGCCATCCACAACTACCTAAAGCTGTTTCTCATATAGGCCAGCCTGTGATTATTG
GAGGGAGCATGGGAACAGGTTCCTATGTATTAGCAGGCGTCAAAGGTTCTGAGCATAAATCTTTTAGCTCGGCATGTCAT
GGAGCAGGTCGCGCTATGAGTCGTCATCAGGCAATGAAGAAATGGAACGGGAAAGACATAGTAGATAAATTGGCTCAACA
AGGAATTTTAATTCGTAGCGGATCATACCGTGGGGTTGCTGAGGAAGCTCCGGGGGCTTATAAAGATGTTCATTCTATTG
TCGATGCCGCTGAAATGTCGGGTTTGGCAAAAAAAGTTGCTAAATTAATTCCCATCATTTGTGTCAAAAGTTAA

Upstream 100 bases:

>100_bases
CACCTATACTGAATTAAAAATATACAAAAATAATGGCATTTGGATAGCTCAATGTGTTGTTGATGTATAAACTCCTTAAC
AGGAATTAATGTGGTGAACA

Downstream 100 bases:

>100_bases
CAATCCATTGTTTATTGAGGTGAAAGGAGCAGCTTATAATTGTAAGGAATTTGTAAAAAAAATGAACTCAAAATAATTTT
CGATAAATTTTTAGACTAAA

Product: replication factor C subunit (activator I)

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 477; Mature: 477

Protein sequence:

>477_residues
MMDLSLLKKINDFEWQIPQHGKMLVPGVIFASEQLILDMDMKVYEQLSNVATLPGIVSAAYAMPDAHWGYGFPIGGVAAF
DPDDGGVISAGGVGFDISCGVRLLSTGLKRDELESVKVSLADALFTHIPAGVGSRGGIHLTIKQLDDMMRGGAQWAVKQG
YGEAADLERIEDRGCVEGAIPDFVSEQAKKRQKNEMGTLGSGNHYLEVQEVRQIYCSDTATALNLHEGDIVVSIHCGSRG
LGHQIGTDYLRSMVIESQHYGIKLADRELACAPIHSKLGENYLGAMRAGINCALANREIITHFMRNVFQDILPRTQIDLI
YDVSHNTCKEEFHEVDGKKKRLFVHRKGATRALGPGHPQLPKAVSHIGQPVIIGGSMGTGSYVLAGVKGSEHKSFSSACH
GAGRAMSRHQAMKKWNGKDIVDKLAQQGILIRSGSYRGVAEEAPGAYKDVHSIVDAAEMSGLAKKVAKLIPIICVKS

Sequences:

>Translated_477_residues
MMDLSLLKKINDFEWQIPQHGKMLVPGVIFASEQLILDMDMKVYEQLSNVATLPGIVSAAYAMPDAHWGYGFPIGGVAAF
DPDDGGVISAGGVGFDISCGVRLLSTGLKRDELESVKVSLADALFTHIPAGVGSRGGIHLTIKQLDDMMRGGAQWAVKQG
YGEAADLERIEDRGCVEGAIPDFVSEQAKKRQKNEMGTLGSGNHYLEVQEVRQIYCSDTATALNLHEGDIVVSIHCGSRG
LGHQIGTDYLRSMVIESQHYGIKLADRELACAPIHSKLGENYLGAMRAGINCALANREIITHFMRNVFQDILPRTQIDLI
YDVSHNTCKEEFHEVDGKKKRLFVHRKGATRALGPGHPQLPKAVSHIGQPVIIGGSMGTGSYVLAGVKGSEHKSFSSACH
GAGRAMSRHQAMKKWNGKDIVDKLAQQGILIRSGSYRGVAEEAPGAYKDVHSIVDAAEMSGLAKKVAKLIPIICVKS
>Mature_477_residues
MMDLSLLKKINDFEWQIPQHGKMLVPGVIFASEQLILDMDMKVYEQLSNVATLPGIVSAAYAMPDAHWGYGFPIGGVAAF
DPDDGGVISAGGVGFDISCGVRLLSTGLKRDELESVKVSLADALFTHIPAGVGSRGGIHLTIKQLDDMMRGGAQWAVKQG
YGEAADLERIEDRGCVEGAIPDFVSEQAKKRQKNEMGTLGSGNHYLEVQEVRQIYCSDTATALNLHEGDIVVSIHCGSRG
LGHQIGTDYLRSMVIESQHYGIKLADRELACAPIHSKLGENYLGAMRAGINCALANREIITHFMRNVFQDILPRTQIDLI
YDVSHNTCKEEFHEVDGKKKRLFVHRKGATRALGPGHPQLPKAVSHIGQPVIIGGSMGTGSYVLAGVKGSEHKSFSSACH
GAGRAMSRHQAMKKWNGKDIVDKLAQQGILIRSGSYRGVAEEAPGAYKDVHSIVDAAEMSGLAKKVAKLIPIICVKS

Specific function: Unknown

COG id: COG1690

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UPF0027 (rtcB) family [H]

Homologues:

Organism=Homo sapiens, GI7657015, Length=497, Percent_Identity=44.2655935613682, Blast_Score=390, Evalue=1e-108,
Organism=Escherichia coli, GI2367224, Length=448, Percent_Identity=29.4642857142857, Blast_Score=132, Evalue=5e-32,
Organism=Caenorhabditis elegans, GI17506665, Length=437, Percent_Identity=46.9107551487414, Blast_Score=379, Evalue=1e-105,
Organism=Drosophila melanogaster, GI24585217, Length=498, Percent_Identity=44.7791164658635, Blast_Score=387, Evalue=1e-108,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001233 [H]

Pfam domain/function: PF01139 UPF0027 [H]

EC number: NA

Molecular weight: Translated: 51564; Mature: 51564

Theoretical pI: Translated: 7.48; Mature: 7.48

Prosite motif: PS01288 UPF0027

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMDLSLLKKINDFEWQIPQHGKMLVPGVIFASEQLILDMDMKVYEQLSNVATLPGIVSAA
CCCHHHHHHCCCCCEECCCCCCEEECEEEEECCCEEEECCHHHHHHHHHHHHHHHHHHHH
YAMPDAHWGYGFPIGGVAAFDPDDGGVISAGGVGFDISCGVRLLSTGLKRDELESVKVSL
HHCCCCCCCCCCCCCCEEEECCCCCCEEECCCCCEEHHCCHHHHHCCCCHHHHHHHHHHH
ADALFTHIPAGVGSRGGIHLTIKQLDDMMRGGAQWAVKQGYGEAADLERIEDRGCVEGAI
HHHHHHHCCCCCCCCCCEEEEHHHHHHHHHCCHHHHHHCCCCCHHHHHHHHHCCCCCCCC
PDFVSEQAKKRQKNEMGTLGSGNHYLEVQEVRQIYCSDTATALNLHEGDIVVSIHCGSRG
HHHHHHHHHHHHHHHCCCCCCCCCEEEHHHHHHHHHCCCCEEEEEECCCEEEEEECCCCC
LGHQIGTDYLRSMVIESQHYGIKLADRELACAPIHSKLGENYLGAMRAGINCALANREII
CCHHHHHHHHHHHHHCCCCCCEEEECCCCEEEHHHHHHCHHHHHHHHHCCEEEECCHHHH
THFMRNVFQDILPRTQIDLIYDVSHNTCKEEFHEVDGKKKRLFVHRKGATRALGPGHPQL
HHHHHHHHHHHCCCCEEEEEEECCCHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCCCCH
PKAVSHIGQPVIIGGSMGTGSYVLAGVKGSEHKSFSSACHGAGRAMSRHQAMKKWNGKDI
HHHHHHCCCCEEEECCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHH
VDKLAQQGILIRSGSYRGVAEEAPGAYKDVHSIVDAAEMSGLAKKVAKLIPIICVKS
HHHHHHCCEEEECCCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECC
>Mature Secondary Structure
MMDLSLLKKINDFEWQIPQHGKMLVPGVIFASEQLILDMDMKVYEQLSNVATLPGIVSAA
CCCHHHHHHCCCCCEECCCCCCEEECEEEEECCCEEEECCHHHHHHHHHHHHHHHHHHHH
YAMPDAHWGYGFPIGGVAAFDPDDGGVISAGGVGFDISCGVRLLSTGLKRDELESVKVSL
HHCCCCCCCCCCCCCCEEEECCCCCCEEECCCCCEEHHCCHHHHHCCCCHHHHHHHHHHH
ADALFTHIPAGVGSRGGIHLTIKQLDDMMRGGAQWAVKQGYGEAADLERIEDRGCVEGAI
HHHHHHHCCCCCCCCCCEEEEHHHHHHHHHCCHHHHHHCCCCCHHHHHHHHHCCCCCCCC
PDFVSEQAKKRQKNEMGTLGSGNHYLEVQEVRQIYCSDTATALNLHEGDIVVSIHCGSRG
HHHHHHHHHHHHHHHCCCCCCCCCEEEHHHHHHHHHCCCCEEEEEECCCEEEEEECCCCC
LGHQIGTDYLRSMVIESQHYGIKLADRELACAPIHSKLGENYLGAMRAGINCALANREII
CCHHHHHHHHHHHHHCCCCCCEEEECCCCEEEHHHHHHCHHHHHHHHHCCEEEECCHHHH
THFMRNVFQDILPRTQIDLIYDVSHNTCKEEFHEVDGKKKRLFVHRKGATRALGPGHPQL
HHHHHHHHHHHCCCCEEEEEEECCCHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCCCCH
PKAVSHIGQPVIIGGSMGTGSYVLAGVKGSEHKSFSSACHGAGRAMSRHQAMKKWNGKDI
HHHHHHCCCCEEEECCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHH
VDKLAQQGILIRSGSYRGVAEEAPGAYKDVHSIVDAAEMSGLAKKVAKLIPIICVKS
HHHHHHCCEEEECCCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA