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The map label for this gene is dtpA [H]

Identifier: 52842411

GI number: 52842411

Start: 2480322

End: 2481827

Strand: Direct

Name: dtpA [H]

Synonym: lpg2198

Alternate gene names: 52842411

Gene position: 2480322-2481827 (Clockwise)

Preceding gene: 52842407

Following gene: 52842418

Centisome position: 73.0

GC content: 36.39

Gene sequence:

>1506_bases
TTGATGATTAAAATAATTCGGGAAATGCCGCATGGAGTTGCTGCGCTCTGCTTAATTCAGGCATTTTCAACTTTTTCATA
CGCTGTTCAATATTCTTCGCTCGCACTTTTTATTACCAAACAACTTGGAATTGCCAATTTATCAGCCAATAGCATAGTGG
GCCTGTTTTTAAGTTTTAGCTATATTTTTCAACTAATTGGCGGTGTCATCGGAAGCCGTTTTATAAGTAACAGACTACTA
TTTGTTACAACTATTCTTATTCAAAATATGGGTTTATTCTTTTTAGCGCAAGCAAATCCTTCCTTGCTTAACATAGGCTT
AAGTTTGTTTATGGTAGGTTCTGGTTTGAATGTTACTTCCAGCAACAGCATGCTTACTCAATGTTTCATACCACAAGATG
ATCGCAGGGAAAGCGCATTTTTTCTCAGTTATGCCGGCATGAATGTCGGTTATTGCATAGGTTATATAGCCTGCGGTTTT
TTTGATTACTCCAACCAGTATCAATATTTGCTCTATGCAAGCATCCTGACTAACTCCATTGCTTTATTGATTATTATTAA
AAACTGGGCCTACCTTGGCGATAAAAATTTTCCATTACCCAATCTCACTAAACGAAACTGGTATTTCATAAAAAATATTC
TGGCAATAGCATTCATTACATTCCTTATTCCTTTTATGCGGGTATGTTTTGAATTTGCAAACTTTTGTAATGGATTGGTA
ATAATTACCTGTTTATTCATGTTTCTTATTATCTTTATCCTGGGGCTAAAACAAAAATCCTCCTCCGACAGGAAAAAAAT
GATGGCATATTTAATTTTGGCAATCAGTTCGGTTTTATTTTGGATGATTTATCTAACTGGCCCAATGGGTGTAACTCTTT
TTGTCAAAAATAATGTGGATAAGCATCTTTTCAGCTTTGAATTGGCTACTCAATGGATAAAAAATATTAATCCCGTGGTC
ATTATTTTCGGAGCACCAATCATGTCCATGCTCATTAACAAATTAAAAGCAAAAGGTTTTCATGTCTCTGCTCCTGTGCA
ATTTTCCTGTTCCTTCGTGTTTTTAGCCCTGTCCTTTTTATGCCTTATCTTTGGAATTATTTGTTCAAATTCCTATGGGT
ATATCAGCATATACTGGATCATAGGCCATCATATCTTGCAAGGAATGTCTGAGTTACTTCTTGGCCCTGTTGGCTATGCA
TTAATTGGAAGAATAGCTCCCCCGAAACTACAAGGGATTTTAATGGGTACCTGGATGCTGGTTATAGGTGTAGCAGCCTC
TTTTTCCCAATATTTCTCCAATGCCATGGTGCAATCAGAATCGGTAGACCCCCTAATTACAAATCAGGATTTTCTAACCG
CATTTAAGCAATTGGGACTTTGGTCTTTACTCTGTGCTGCCTTGTTATATTTTGTTTCAGGTAAATTAACCAGGATAATA
AATGGTACAAAAGACAATAAATCAGTTAATGAGAGCAAGGCTCTCCCCATGCCTTACTCTAACTAA

Upstream 100 bases:

>100_bases
AAGTAAAGTTTGGAAAGAAATTGAATGGCAGGTTGTTACATTCTTGAAGGCAACTGATTATTGATGGTAAAGTCTATTCT
CATAAAATCAGCCAAAATGT

Downstream 100 bases:

>100_bases
TCATTTAAAAATCTAAAGTATTGCTTTGCTCAGCGGGTTCTTCCAGACGAGTAGCAACATCCAGGTAAATTTTCGGATTG
TACTGGCACAAACGTAAGAA

Product: POT family peptide transport protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 501; Mature: 501

Protein sequence:

>501_residues
MMIKIIREMPHGVAALCLIQAFSTFSYAVQYSSLALFITKQLGIANLSANSIVGLFLSFSYIFQLIGGVIGSRFISNRLL
FVTTILIQNMGLFFLAQANPSLLNIGLSLFMVGSGLNVTSSNSMLTQCFIPQDDRRESAFFLSYAGMNVGYCIGYIACGF
FDYSNQYQYLLYASILTNSIALLIIIKNWAYLGDKNFPLPNLTKRNWYFIKNILAIAFITFLIPFMRVCFEFANFCNGLV
IITCLFMFLIIFILGLKQKSSSDRKKMMAYLILAISSVLFWMIYLTGPMGVTLFVKNNVDKHLFSFELATQWIKNINPVV
IIFGAPIMSMLINKLKAKGFHVSAPVQFSCSFVFLALSFLCLIFGIICSNSYGYISIYWIIGHHILQGMSELLLGPVGYA
LIGRIAPPKLQGILMGTWMLVIGVAASFSQYFSNAMVQSESVDPLITNQDFLTAFKQLGLWSLLCAALLYFVSGKLTRII
NGTKDNKSVNESKALPMPYSN

Sequences:

>Translated_501_residues
MMIKIIREMPHGVAALCLIQAFSTFSYAVQYSSLALFITKQLGIANLSANSIVGLFLSFSYIFQLIGGVIGSRFISNRLL
FVTTILIQNMGLFFLAQANPSLLNIGLSLFMVGSGLNVTSSNSMLTQCFIPQDDRRESAFFLSYAGMNVGYCIGYIACGF
FDYSNQYQYLLYASILTNSIALLIIIKNWAYLGDKNFPLPNLTKRNWYFIKNILAIAFITFLIPFMRVCFEFANFCNGLV
IITCLFMFLIIFILGLKQKSSSDRKKMMAYLILAISSVLFWMIYLTGPMGVTLFVKNNVDKHLFSFELATQWIKNINPVV
IIFGAPIMSMLINKLKAKGFHVSAPVQFSCSFVFLALSFLCLIFGIICSNSYGYISIYWIIGHHILQGMSELLLGPVGYA
LIGRIAPPKLQGILMGTWMLVIGVAASFSQYFSNAMVQSESVDPLITNQDFLTAFKQLGLWSLLCAALLYFVSGKLTRII
NGTKDNKSVNESKALPMPYSN
>Mature_501_residues
MMIKIIREMPHGVAALCLIQAFSTFSYAVQYSSLALFITKQLGIANLSANSIVGLFLSFSYIFQLIGGVIGSRFISNRLL
FVTTILIQNMGLFFLAQANPSLLNIGLSLFMVGSGLNVTSSNSMLTQCFIPQDDRRESAFFLSYAGMNVGYCIGYIACGF
FDYSNQYQYLLYASILTNSIALLIIIKNWAYLGDKNFPLPNLTKRNWYFIKNILAIAFITFLIPFMRVCFEFANFCNGLV
IITCLFMFLIIFILGLKQKSSSDRKKMMAYLILAISSVLFWMIYLTGPMGVTLFVKNNVDKHLFSFELATQWIKNINPVV
IIFGAPIMSMLINKLKAKGFHVSAPVQFSCSFVFLALSFLCLIFGIICSNSYGYISIYWIIGHHILQGMSELLLGPVGYA
LIGRIAPPKLQGILMGTWMLVIGVAASFSQYFSNAMVQSESVDPLITNQDFLTAFKQLGLWSLLCAALLYFVSGKLTRII
NGTKDNKSVNESKALPMPYSN

Specific function: Proton-dependent permease that transports di- and tripeptides [H]

COG id: COG3104

COG function: function code E; Dipeptide/tripeptide permease

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PTR2/POT transporter (TC 2.A.17) family. DtpA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787922, Length=477, Percent_Identity=24.9475890985325, Blast_Score=145, Evalue=6e-36,
Organism=Escherichia coli, GI1789911, Length=491, Percent_Identity=25.4582484725051, Blast_Score=142, Evalue=4e-35,
Organism=Escherichia coli, GI1790572, Length=501, Percent_Identity=24.1516966067864, Blast_Score=117, Evalue=2e-27,
Organism=Escherichia coli, GI1786927, Length=434, Percent_Identity=23.7327188940092, Blast_Score=115, Evalue=4e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR016196
- InterPro:   IPR000109
- InterPro:   IPR005279
- InterPro:   IPR018456 [H]

Pfam domain/function: PF00854 PTR2 [H]

EC number: NA

Molecular weight: Translated: 55932; Mature: 55932

Theoretical pI: Translated: 9.49; Mature: 9.49

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMIKIIREMPHGVAALCLIQAFSTFSYAVQYSSLALFITKQLGIANLSANSIVGLFLSFS
CHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHH
YIFQLIGGVIGSRFISNRLLFVTTILIQNMGLFFLAQANPSLLNIGLSLFMVGSGLNVTS
HHHHHHHHHHHHHHHHCHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHEECCCCCCCC
SNSMLTQCFIPQDDRRESAFFLSYAGMNVGYCIGYIACGFFDYSNQYQYLLYASILTNSI
CCCEEEEEECCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCC
ALLIIIKNWAYLGDKNFPLPNLTKRNWYFIKNILAIAFITFLIPFMRVCFEFANFCNGLV
EEEEEEECHHEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHH
IITCLFMFLIIFILGLKQKSSSDRKKMMAYLILAISSVLFWMIYLTGPMGVTLFVKNNVD
HHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCH
KHLFSFELATQWIKNINPVVIIFGAPIMSMLINKLKAKGFHVSAPVQFSCSFVFLALSFL
HHHHHHHHHHHHHHCCCCEEEEECHHHHHHHHHHHHCCCEEECCCCHHHHHHHHHHHHHH
CLIFGIICSNSYGYISIYWIIGHHILQGMSELLLGPVGYALIGRIAPPKLQGILMGTWML
HHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
VIGVAASFSQYFSNAMVQSESVDPLITNQDFLTAFKQLGLWSLLCAALLYFVSGKLTRII
HHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCHHHHHHHHHHHHHCCCHHHHH
NGTKDNKSVNESKALPMPYSN
CCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MMIKIIREMPHGVAALCLIQAFSTFSYAVQYSSLALFITKQLGIANLSANSIVGLFLSFS
CHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHH
YIFQLIGGVIGSRFISNRLLFVTTILIQNMGLFFLAQANPSLLNIGLSLFMVGSGLNVTS
HHHHHHHHHHHHHHHHCHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHEECCCCCCCC
SNSMLTQCFIPQDDRRESAFFLSYAGMNVGYCIGYIACGFFDYSNQYQYLLYASILTNSI
CCCEEEEEECCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCC
ALLIIIKNWAYLGDKNFPLPNLTKRNWYFIKNILAIAFITFLIPFMRVCFEFANFCNGLV
EEEEEEECHHEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHH
IITCLFMFLIIFILGLKQKSSSDRKKMMAYLILAISSVLFWMIYLTGPMGVTLFVKNNVD
HHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCH
KHLFSFELATQWIKNINPVVIIFGAPIMSMLINKLKAKGFHVSAPVQFSCSFVFLALSFL
HHHHHHHHHHHHHHCCCCEEEEECHHHHHHHHHHHHCCCEEECCCCHHHHHHHHHHHHHH
CLIFGIICSNSYGYISIYWIIGHHILQGMSELLLGPVGYALIGRIAPPKLQGILMGTWML
HHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
VIGVAASFSQYFSNAMVQSESVDPLITNQDFLTAFKQLGLWSLLCAALLYFVSGKLTRII
HHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCHHHHHHHHHHHHHCCCHHHHH
NGTKDNKSVNESKALPMPYSN
CCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11677608; 12644504 [H]