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The map label for this gene is tnpA [H]

Identifier: 52842397

GI number: 52842397

Start: 2457486

End: 2458892

Strand: Reverse

Name: tnpA [H]

Synonym: lpg2184

Alternate gene names: 52842397

Gene position: 2458892-2457486 (Counterclockwise)

Preceding gene: 52842398

Following gene: 52842389

Centisome position: 72.37

GC content: 38.31

Gene sequence:

>1407_bases
ATGGCTAGTTGTGAATGGATTATTAATGAATCCAAGGAAGCGAACTTCGGTGATAAGCGGTTAGATAAGCGTTATGGAGA
TATCTTAAGCGGGTTACTTAGCTCACCAAATGCAAGCATTCCAACTACATTTCAAAGTTGGAATGAAACACTGGCAGCCT
ACCGGTTTTTTAACCATGTGAATGTAAATCCGGAATCAATTCTTTTACCCCATTCTGAAGCGACACTAGAACGTATAAAA
GCAGAAAAGATAGTTCTAATTCCCCAAGACACAACAGAGGTAGATTTTACAGGTAGAAAATCATTGTCAGGCATGGGTTA
TCTCTCCAACGAGAGAAGCCGGGGATTATATTTACATCCAAGCATTGCATTTACGCCAGAACGAGTTTGTTTGGGCGTAG
TAGAAATGCAGCATTGGATAAGAAAAGAGATTGGTACGAGGAATAGTAGAAAGGGAAAGTCAATTGAGGAAAAGGAAACC
TATTGTTGGCTTAAGGGCTATAATGCAGCGAATAAAATTGCACTGGCAGTACCCGATACAATGGTTGTCAGTATTTCCGA
TAGAGAGGGAGATATTTATGAGGTTCTTGAAAAACTTCCCTCCGAAGAAAATAAAGCCTATTGGCTTATACGTTGTCAGC
ATGATAGAGCTGTTTTGAATGAAGAAACAAATCAATTCGAGTTACTTCTTAAAAAAGAAGTTAGCAAAGCTTGTGTTCTT
GGCACCATAGAGTTTGAAATTCCCGCAGGCACTTCCTATAGAAATTGCAAAAAAAGACATACTCGAAAAGCCCGTAGCGT
TAGACAGGAGATTCGTATATGTAGTGTTTCTTTAAGGCCTCCTCGTCGAAAAAGCAAAAAATTGAACGTCATTGAAATTC
AGGTTGTACACTGCAAAGAAATAAATACACCAGAAGGGGAGCAACCCGTTGAATGGTTTCTAATCACAAGTGTCCCTATA
AAAACACTGGATCGGGCAGTTGAAATTGTTAATTGGTATTTATGTAGGTGGTTAATAGAAATGTACATAAAAATTTTAAA
GAGTGGATGCAAGATAGAGGAATTACGATTTGAAACTTACGAGGCTACTCTTAATTGCATCGCTTTTTATATGATAGTGG
CATGGCGGGTATTTTATTTAACAATGTTGGGACGAACTTGCCCTGATATAGACTGTACAACAGTCTTTGAAGATAACGAA
TGGCAAGCCACTTATGCCATGGCAACAAAGAAAAAACCACCAAAAAAACCACCTAAACTTTATGAAATTATTTTAATGAT
CGCAAAATTTGGAGGACATTTAGGAAGAGGCTCTGATGGCTTCCCTGGAACAAAAGTCATGTGGATTGGTCTACAACGCA
TGAAAGATTTTACTTTGGCTTGGGAAACCTTTCATACATTGAGTTAG

Upstream 100 bases:

>100_bases
AAGATTTTGTATGGGAATACCATATCCGCTCCCTGATAGTCATACTCTTATACATAAGTATTAATCCATGTAAAATTCAT
ATTTTTTATATGGAACTTAG

Downstream 100 bases:

>100_bases
AATAACTTATGTATAAGAGTATGCCCTGATAGTTGCGGCTCGGATTATGGTTCAAACACTGAACCGCGACTGTCAGGGAG
CAGATAAAAATAATCCAGCA

Product: hypothetical protein

Products: NA

Alternate protein names: Tnp [H]

Number of amino acids: Translated: 468; Mature: 467

Protein sequence:

>468_residues
MASCEWIINESKEANFGDKRLDKRYGDILSGLLSSPNASIPTTFQSWNETLAAYRFFNHVNVNPESILLPHSEATLERIK
AEKIVLIPQDTTEVDFTGRKSLSGMGYLSNERSRGLYLHPSIAFTPERVCLGVVEMQHWIRKEIGTRNSRKGKSIEEKET
YCWLKGYNAANKIALAVPDTMVVSISDREGDIYEVLEKLPSEENKAYWLIRCQHDRAVLNEETNQFELLLKKEVSKACVL
GTIEFEIPAGTSYRNCKKRHTRKARSVRQEIRICSVSLRPPRRKSKKLNVIEIQVVHCKEINTPEGEQPVEWFLITSVPI
KTLDRAVEIVNWYLCRWLIEMYIKILKSGCKIEELRFETYEATLNCIAFYMIVAWRVFYLTMLGRTCPDIDCTTVFEDNE
WQATYAMATKKKPPKKPPKLYEIILMIAKFGGHLGRGSDGFPGTKVMWIGLQRMKDFTLAWETFHTLS

Sequences:

>Translated_468_residues
MASCEWIINESKEANFGDKRLDKRYGDILSGLLSSPNASIPTTFQSWNETLAAYRFFNHVNVNPESILLPHSEATLERIK
AEKIVLIPQDTTEVDFTGRKSLSGMGYLSNERSRGLYLHPSIAFTPERVCLGVVEMQHWIRKEIGTRNSRKGKSIEEKET
YCWLKGYNAANKIALAVPDTMVVSISDREGDIYEVLEKLPSEENKAYWLIRCQHDRAVLNEETNQFELLLKKEVSKACVL
GTIEFEIPAGTSYRNCKKRHTRKARSVRQEIRICSVSLRPPRRKSKKLNVIEIQVVHCKEINTPEGEQPVEWFLITSVPI
KTLDRAVEIVNWYLCRWLIEMYIKILKSGCKIEELRFETYEATLNCIAFYMIVAWRVFYLTMLGRTCPDIDCTTVFEDNE
WQATYAMATKKKPPKKPPKLYEIILMIAKFGGHLGRGSDGFPGTKVMWIGLQRMKDFTLAWETFHTLS
>Mature_467_residues
ASCEWIINESKEANFGDKRLDKRYGDILSGLLSSPNASIPTTFQSWNETLAAYRFFNHVNVNPESILLPHSEATLERIKA
EKIVLIPQDTTEVDFTGRKSLSGMGYLSNERSRGLYLHPSIAFTPERVCLGVVEMQHWIRKEIGTRNSRKGKSIEEKETY
CWLKGYNAANKIALAVPDTMVVSISDREGDIYEVLEKLPSEENKAYWLIRCQHDRAVLNEETNQFELLLKKEVSKACVLG
TIEFEIPAGTSYRNCKKRHTRKARSVRQEIRICSVSLRPPRRKSKKLNVIEIQVVHCKEINTPEGEQPVEWFLITSVPIK
TLDRAVEIVNWYLCRWLIEMYIKILKSGCKIEELRFETYEATLNCIAFYMIVAWRVFYLTMLGRTCPDIDCTTVFEDNEW
QATYAMATKKKPPKKPPKLYEIILMIAKFGGHLGRGSDGFPGTKVMWIGLQRMKDFTLAWETFHTLS

Specific function: Mediates transposition of transposon Tn5 by a 'cut and paste' mechanism. First, the monomeric transposase binds the 19 bp inverted DNA repeats flanking the transposon. Then, dimerization of the DNA-bound transposase creates a synaptic DNA complex. After n

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transposase 11 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012337
- InterPro:   IPR002559
- InterPro:   IPR003201
- InterPro:   IPR014737
- InterPro:   IPR014736
- InterPro:   IPR014735 [H]

Pfam domain/function: PF01609 Transposase_11; PF02281 Transposase_Tn5 [H]

EC number: NA

Molecular weight: Translated: 53972; Mature: 53841

Theoretical pI: Translated: 8.66; Mature: 8.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.8 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
2.8 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASCEWIINESKEANFGDKRLDKRYGDILSGLLSSPNASIPTTFQSWNETLAAYRFFNHV
CCCCCEEECCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCC
NVNPESILLPHSEATLERIKAEKIVLIPQDTTEVDFTGRKSLSGMGYLSNERSRGLYLHP
CCCCCEEEECCCHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCEEECC
SIAFTPERVCLGVVEMQHWIRKEIGTRNSRKGKSIEEKETYCWLKGYNAANKIALAVPDT
CCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEECCCCCCEEEEEECCE
MVVSISDREGDIYEVLEKLPSEENKAYWLIRCQHDRAVLNEETNQFELLLKKEVSKACVL
EEEEEECCCCHHHHHHHHCCCCCCCEEEEEEECCCHHHHCCCCCHHHHHHHHHHCCEEEE
GTIEFEIPAGTSYRNCKKRHTRKARSVRQEIRICSVSLRPPRRKSKKLNVIEIQVVHCKE
EEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCCCCCEEEEEEEEEEC
INTPEGEQPVEWFLITSVPIKTLDRAVEIVNWYLCRWLIEMYIKILKSGCKIEELRFETY
CCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHH
EATLNCIAFYMIVAWRVFYLTMLGRTCPDIDCTTVFEDNEWQATYAMATKKKPPKKPPKL
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCEEEEEEECCCCCCCCCHHH
YEIILMIAKFGGHLGRGSDGFPGTKVMWIGLQRMKDFTLAWETFHTLS
HHHHHHHHHHCCCCCCCCCCCCCCEEEEEEHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
ASCEWIINESKEANFGDKRLDKRYGDILSGLLSSPNASIPTTFQSWNETLAAYRFFNHV
CCCCEEECCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCC
NVNPESILLPHSEATLERIKAEKIVLIPQDTTEVDFTGRKSLSGMGYLSNERSRGLYLHP
CCCCCEEEECCCHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCEEECC
SIAFTPERVCLGVVEMQHWIRKEIGTRNSRKGKSIEEKETYCWLKGYNAANKIALAVPDT
CCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEECCCCCCEEEEEECCE
MVVSISDREGDIYEVLEKLPSEENKAYWLIRCQHDRAVLNEETNQFELLLKKEVSKACVL
EEEEEECCCCHHHHHHHHCCCCCCCEEEEEEECCCHHHHCCCCCHHHHHHHHHHCCEEEE
GTIEFEIPAGTSYRNCKKRHTRKARSVRQEIRICSVSLRPPRRKSKKLNVIEIQVVHCKE
EEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCCCCCEEEEEEEEEEC
INTPEGEQPVEWFLITSVPIKTLDRAVEIVNWYLCRWLIEMYIKILKSGCKIEELRFETY
CCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHH
EATLNCIAFYMIVAWRVFYLTMLGRTCPDIDCTTVFEDNEWQATYAMATKKKPPKKPPKL
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCEEEEEEECCCCCCCCCHHH
YEIILMIAKFGGHLGRGSDGFPGTKVMWIGLQRMKDFTLAWETFHTLS
HHHHHHHHHHCCCCCCCCCCCCCCEEEEEEHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 6260374; 6271452; 7867940; 6291786; 10884228; 12367522; 11896402 [H]