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The map label for this gene is ahcY [H]

Identifier: 52842386

GI number: 52842386

Start: 2437187

End: 2438290

Strand: Reverse

Name: ahcY [H]

Synonym: lpg2172

Alternate gene names: 52842386

Gene position: 2438290-2437187 (Counterclockwise)

Preceding gene: 52842389

Following gene: 52842382

Centisome position: 71.76

GC content: 39.4

Gene sequence:

>1104_bases
ATGCACCAGGAGTTATTAAAGTACTTAGAAATGTATCACCCGCAAATTGCGCCATTTATGCATCTTCAGATTAATGAATG
GGACAAAAACAGGCCACTGGAAGGAGTGAAAATACTGCATCATGTGCCTTTGGTTCCCAATACACTGCTAAAAATAGCAG
CTCTTGTCGCTGCAAATGCTGAGGTGACCGTAACCAATCCAGCCTCTTTTTGTCAGGCACATCCTGATGCGATTACTTGT
CTTCATAATTCAGGAATTGCTTATGTTGAAAATCTTGACCTTTTAAGAGATGAAACGTTCGATGTTTATATGGATTGTGG
CGGGCAGCTTCATCAGCGTCTCGGAAGACCTTTGACGGGAGCTATAGAGTTAACAGGCTCAGGGGATCAGTATTATCGTA
GTCTGAAAACACTTGATTTTCCGGTTATAAGCATTGATCACACAATGACGAAACAATTGGAAACAGTATTTGGCTGTGCT
GAAAGTTCTCACCAAGCGATTCAAAAACTCACTGGTGTCGATCCCACAAACAAGAATTGGCTAATCTTTGGGTTTGGTAA
AATAGGGCGAGGGCTCGCTTATTTTTGTCTGGAACATCAAGTACCAGTTACTGTAGTGGATAGTTCAGTCCATCAATGTG
ATTTAGCTTTCAATCTTGGTATAGAGGCTATTAGACCCGAGGAGCATGATAAGCTCGAAAAAGCTGTGGCTAAAGCAGAT
ATTATATTAACTGCAACGGGCGGTAAAAATATCATGAGCGAATATCCCAGAGCCTGGTTTGATGGCAAAATTTTGGGGAA
TTTAGGACTGCATGATGAGTTTGGTCCCAATTTCACCTCTCAGGATGTATTATACGATAAAAAACCTATTAATTTTTGCC
TATATGATCCTACGCCAATGATTTTTATAGATCCTGAGTTTTATTTGCATAATCTGGGATGTTTATTGCTTTTACAGGGA
AATTTTCCTCGAGGAATGCATGATATTCCTGAAGATATAGATTCCTCTATTATTAAAGACTGGTGCCAATATCATAGGCG
TTCTGAAAAAAGTATTCGATGTTGGTTTCTGACTTCCCAGGATTTTTCTCTTAAAACAAATTAA

Upstream 100 bases:

>100_bases
TGGGGTAGAGCCATTAAAATATGCTTTATTAATTCGTGTTATTGTTAATGAGTTTTATTATAGTATTGTCATTCTTTCTC
ATACTCATATGGTCTAAATA

Downstream 100 bases:

>100_bases
TATAAACAGTTCGAATAAGACGGTTTATAGGCACTTTAATTAGTCTATTTAATTGAAAATTACTTTTTCAGGACTTCTGA
ATATCAATAAGATGTGGGGA

Product: adenosylhomocysteinase

Products: NA

Alternate protein names: S-adenosyl-L-homocysteine hydrolase; AdoHcyase [H]

Number of amino acids: Translated: 367; Mature: 367

Protein sequence:

>367_residues
MHQELLKYLEMYHPQIAPFMHLQINEWDKNRPLEGVKILHHVPLVPNTLLKIAALVAANAEVTVTNPASFCQAHPDAITC
LHNSGIAYVENLDLLRDETFDVYMDCGGQLHQRLGRPLTGAIELTGSGDQYYRSLKTLDFPVISIDHTMTKQLETVFGCA
ESSHQAIQKLTGVDPTNKNWLIFGFGKIGRGLAYFCLEHQVPVTVVDSSVHQCDLAFNLGIEAIRPEEHDKLEKAVAKAD
IILTATGGKNIMSEYPRAWFDGKILGNLGLHDEFGPNFTSQDVLYDKKPINFCLYDPTPMIFIDPEFYLHNLGCLLLLQG
NFPRGMHDIPEDIDSSIIKDWCQYHRRSEKSIRCWFLTSQDFSLKTN

Sequences:

>Translated_367_residues
MHQELLKYLEMYHPQIAPFMHLQINEWDKNRPLEGVKILHHVPLVPNTLLKIAALVAANAEVTVTNPASFCQAHPDAITC
LHNSGIAYVENLDLLRDETFDVYMDCGGQLHQRLGRPLTGAIELTGSGDQYYRSLKTLDFPVISIDHTMTKQLETVFGCA
ESSHQAIQKLTGVDPTNKNWLIFGFGKIGRGLAYFCLEHQVPVTVVDSSVHQCDLAFNLGIEAIRPEEHDKLEKAVAKAD
IILTATGGKNIMSEYPRAWFDGKILGNLGLHDEFGPNFTSQDVLYDKKPINFCLYDPTPMIFIDPEFYLHNLGCLLLLQG
NFPRGMHDIPEDIDSSIIKDWCQYHRRSEKSIRCWFLTSQDFSLKTN
>Mature_367_residues
MHQELLKYLEMYHPQIAPFMHLQINEWDKNRPLEGVKILHHVPLVPNTLLKIAALVAANAEVTVTNPASFCQAHPDAITC
LHNSGIAYVENLDLLRDETFDVYMDCGGQLHQRLGRPLTGAIELTGSGDQYYRSLKTLDFPVISIDHTMTKQLETVFGCA
ESSHQAIQKLTGVDPTNKNWLIFGFGKIGRGLAYFCLEHQVPVTVVDSSVHQCDLAFNLGIEAIRPEEHDKLEKAVAKAD
IILTATGGKNIMSEYPRAWFDGKILGNLGLHDEFGPNFTSQDVLYDKKPINFCLYDPTPMIFIDPEFYLHNLGCLLLLQG
NFPRGMHDIPEDIDSSIIKDWCQYHRRSEKSIRCWFLTSQDFSLKTN

Specific function: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine [H]

COG id: COG0499

COG function: function code H; S-adenosylhomocysteine hydrolase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the adenosylhomocysteinase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000043
- InterPro:   IPR015878
- InterPro:   IPR020082 [H]

Pfam domain/function: PF05221 AdoHcyase; PF00670 AdoHcyase_NAD [H]

EC number: =3.3.1.1 [H]

Molecular weight: Translated: 41514; Mature: 41514

Theoretical pI: Translated: 5.92; Mature: 5.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHQELLKYLEMYHPQIAPFMHLQINEWDKNRPLEGVKILHHVPLVPNTLLKIAALVAANA
CCHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCHHHHHHHCCCCHHHHHHHHHHHHCCC
EVTVTNPASFCQAHPDAITCLHNSGIAYVENLDLLRDETFDVYMDCGGQLHQRLGRPLTG
EEEEECCHHHHHCCCCEEEEEECCCEEEEECCHHHHCCCEEEEECCCHHHHHHHCCCCEE
AIELTGSGDQYYRSLKTLDFPVISIDHTMTKQLETVFGCAESSHQAIQKLTGVDPTNKNW
EEEEECCCHHHHHHHHHCCCCEEEECHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCE
LIFGFGKIGRGLAYFCLEHQVPVTVVDSSVHQCDLAFNLGIEAIRPEEHDKLEKAVAKAD
EEEECCCCCCCCEEEHHCCCCCEEEECCCCHHEEEEEECCCEEECCCHHHHHHHHHHHCC
IILTATGGKNIMSEYPRAWFDGKILGNLGLHDEFGPNFTSQDVLYDKKPINFCLYDPTPM
EEEEECCCCHHHHHCCCCCCCCEEEECCCCCCCCCCCCCCCCCEECCCCCCEEEECCCCE
IFIDPEFYLHNLGCLLLLQGNFPRGMHDIPEDIDSSIIKDWCQYHRRSEKSIRCWFLTSQ
EEECCHHHHHCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEEECC
DFSLKTN
CCEEECC
>Mature Secondary Structure
MHQELLKYLEMYHPQIAPFMHLQINEWDKNRPLEGVKILHHVPLVPNTLLKIAALVAANA
CCHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCHHHHHHHCCCCHHHHHHHHHHHHCCC
EVTVTNPASFCQAHPDAITCLHNSGIAYVENLDLLRDETFDVYMDCGGQLHQRLGRPLTG
EEEEECCHHHHHCCCCEEEEEECCCEEEEECCHHHHCCCEEEEECCCHHHHHHHCCCCEE
AIELTGSGDQYYRSLKTLDFPVISIDHTMTKQLETVFGCAESSHQAIQKLTGVDPTNKNW
EEEEECCCHHHHHHHHHCCCCEEEECHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCE
LIFGFGKIGRGLAYFCLEHQVPVTVVDSSVHQCDLAFNLGIEAIRPEEHDKLEKAVAKAD
EEEECCCCCCCCEEEHHCCCCCEEEECCCCHHEEEEEECCCEEECCCHHHHHHHHHHHCC
IILTATGGKNIMSEYPRAWFDGKILGNLGLHDEFGPNFTSQDVLYDKKPINFCLYDPTPM
EEEEECCCCHHHHHCCCCCCCCEEEECCCCCCCCCCCCCCCCCEECCCCCCEEEECCCCE
IFIDPEFYLHNLGCLLLLQGNFPRGMHDIPEDIDSSIIKDWCQYHRRSEKSIRCWFLTSQ
EEECCHHHHHCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEEECC
DFSLKTN
CCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9389475 [H]