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The map label for this gene is dam

Identifier: 52842289

GI number: 52842289

Start: 2316456

End: 2317292

Strand: Reverse

Name: dam

Synonym: lpg2075

Alternate gene names: 52842289

Gene position: 2317292-2316456 (Counterclockwise)

Preceding gene: 52842290

Following gene: 52842288

Centisome position: 68.2

GC content: 35.24

Gene sequence:

>837_bases
ATGATAAAAAATAGTGAAAAGGAATCAATAATCCGCATTAGACCATTTTTAAAATGGGCCGGCGGTAAGTTCCAGATAAT
AAATAAAATTCGTGCGAGCCTACCTAAAGGGGCTCGTTTGATTGAACCGTTTGTAGGTTCAGGAGCAGTTTTTTTAAATA
CGAACTATAACAAGTTTATACTCGCTGATATTAATGCTGATCTAATTAACTTGTTTGAACATTTGAAGTTTGAAAAGCAT
GATTTTATCCATTTTTGTAAGCAATTTTTTACTGCTGAATTTAATAAAAAATCAACCTTCCTATCATTGCGTACAGAATT
TAATTCAACTACAGATAGCCACTTGAAGGCTGCACTATTTATTTATCTCAATCGTCATGCTTTTAATGGCCTCATGAGGT
ACAACAGTTCTGGCATGTTTAACACGGCTTTTGGGGATTATAAAAAACCTTATTTTCCAGAAAATGAAATGTTGGTTTTT
ATTCAAAAAGCGGAAAAAGCAGAATTTAAATGTGCTGATTATAGCGTAATTATGGGAGAAGCTATTAAAGGAGATGTAGT
TTATTGCGACCCCCCATATGTTCCATTATCTGCATCAGCCAATTTTACAAAATATCATTCCACAGCTTTTGGACAAGAAG
ACCAGAGACGATTAGTTGAGTTAGCTAAAGAACTGGCTGCGAAGGGGATTCCTGTAATTTTATCTAATCATGATACGGCT
TTTACTCAGAATTTATATCAAGGATCAAGCATTATCAGTTTTGAGGTGCAACGGAATATCAGTTGTAACGGGAGCACAAG
GGGACGAGCACGTGAAATGCTTGCCCTATTTAATTAG

Upstream 100 bases:

>100_bases
AAGTGAAATAACATAAGGCGGAGCGCCACTGTTTAATTATAGAGCATAAATGAGTCCTAATTTTCTAAACTAGGCTAAAA
TTAGATAAAAAGGATAAATA

Downstream 100 bases:

>100_bases
GGGTGTTGCCATGAAGCAGGGTGGTTCATATGCAAATAGTAGCGGAAAGGTTCTTGAGGGATTAGTAGAGTTCGCTCTAA
CAAAAAAGGGCTTTACTGTA

Product: DNA adenine methylase

Products: NA

Alternate protein names: DNA adenine methyltransferase; Deoxyadenosyl-methyltransferase; M.SmaII [H]

Number of amino acids: Translated: 278; Mature: 278

Protein sequence:

>278_residues
MIKNSEKESIIRIRPFLKWAGGKFQIINKIRASLPKGARLIEPFVGSGAVFLNTNYNKFILADINADLINLFEHLKFEKH
DFIHFCKQFFTAEFNKKSTFLSLRTEFNSTTDSHLKAALFIYLNRHAFNGLMRYNSSGMFNTAFGDYKKPYFPENEMLVF
IQKAEKAEFKCADYSVIMGEAIKGDVVYCDPPYVPLSASANFTKYHSTAFGQEDQRRLVELAKELAAKGIPVILSNHDTA
FTQNLYQGSSIISFEVQRNISCNGSTRGRAREMLALFN

Sequences:

>Translated_278_residues
MIKNSEKESIIRIRPFLKWAGGKFQIINKIRASLPKGARLIEPFVGSGAVFLNTNYNKFILADINADLINLFEHLKFEKH
DFIHFCKQFFTAEFNKKSTFLSLRTEFNSTTDSHLKAALFIYLNRHAFNGLMRYNSSGMFNTAFGDYKKPYFPENEMLVF
IQKAEKAEFKCADYSVIMGEAIKGDVVYCDPPYVPLSASANFTKYHSTAFGQEDQRRLVELAKELAAKGIPVILSNHDTA
FTQNLYQGSSIISFEVQRNISCNGSTRGRAREMLALFN
>Mature_278_residues
MIKNSEKESIIRIRPFLKWAGGKFQIINKIRASLPKGARLIEPFVGSGAVFLNTNYNKFILADINADLINLFEHLKFEKH
DFIHFCKQFFTAEFNKKSTFLSLRTEFNSTTDSHLKAALFIYLNRHAFNGLMRYNSSGMFNTAFGDYKKPYFPENEMLVF
IQKAEKAEFKCADYSVIMGEAIKGDVVYCDPPYVPLSASANFTKYHSTAFGQEDQRRLVELAKELAAKGIPVILSNHDTA
FTQNLYQGSSIISFEVQRNISCNGSTRGRAREMLALFN

Specific function: Methylates DNA within the sequence GATC. Directly involved in methyl-directed DNA mismatch repair [H]

COG id: COG0338

COG function: function code L; Site-specific DNA methylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the N(4)/N(6)-methyltransferase family [H]

Homologues:

Organism=Escherichia coli, GI1789789, Length=264, Percent_Identity=48.8636363636364, Blast_Score=280, Evalue=5e-77,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023095
- InterPro:   IPR002052
- InterPro:   IPR012327 [H]

Pfam domain/function: PF02086 MethyltransfD12 [H]

EC number: =2.1.1.72 [H]

Molecular weight: Translated: 31687; Mature: 31687

Theoretical pI: Translated: 9.56; Mature: 9.56

Prosite motif: PS00092 N6_MTASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKNSEKESIIRIRPFLKWAGGKFQIINKIRASLPKGARLIEPFVGSGAVFLNTNYNKFI
CCCCCCCCCEEEEEHHHHHCCCHHHHHHHHHHCCCCCCEEHHHHCCCCEEEEECCCCEEE
LADINADLINLFEHLKFEKHDFIHFCKQFFTAEFNKKSTFLSLRTEFNSTTDSHLKAALF
EEECCHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCHHHHHEEEE
IYLNRHAFNGLMRYNSSGMFNTAFGDYKKPYFPENEMLVFIQKAEKAEFKCADYSVIMGE
EEEHHHHHHHHHEECCCCCEECCCCCCCCCCCCCCCEEEEEEECCCCCEEECCEEEEECC
AIKGDVVYCDPPYVPLSASANFTKYHSTAFGQEDQRRLVELAKELAAKGIPVILSNHDTA
CCCCCEEEECCCCCEEECCCCCEEECCCCCCCHHHHHHHHHHHHHHHCCCCEEEECCCHH
FTQNLYQGSSIISFEVQRNISCNGSTRGRAREMLALFN
HHHHHHCCCCEEEEEEEECCCCCCCCCHHHHHHHHHCC
>Mature Secondary Structure
MIKNSEKESIIRIRPFLKWAGGKFQIINKIRASLPKGARLIEPFVGSGAVFLNTNYNKFI
CCCCCCCCCEEEEEHHHHHCCCHHHHHHHHHHCCCCCCEEHHHHCCCCEEEEECCCCEEE
LADINADLINLFEHLKFEKHDFIHFCKQFFTAEFNKKSTFLSLRTEFNSTTDSHLKAALF
EEECCHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCHHHHHEEEE
IYLNRHAFNGLMRYNSSGMFNTAFGDYKKPYFPENEMLVFIQKAEKAEFKCADYSVIMGE
EEEHHHHHHHHHEECCCCCEECCCCCCCCCCCCCCCEEEEEEECCCCCEEECCEEEEECC
AIKGDVVYCDPPYVPLSASANFTKYHSTAFGQEDQRRLVELAKELAAKGIPVILSNHDTA
CCCCCEEEECCCCCEEECCCCCEEECCCCCCCHHHHHHHHHHHHHHHCCCCEEEECCCHH
FTQNLYQGSSIISFEVQRNISCNGSTRGRAREMLALFN
HHHHHHCCCCEEEEEEEECCCCCCCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10383952 [H]