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The map label for this gene is tnpA [H]

Identifier: 52842283

GI number: 52842283

Start: 2309882

End: 2311333

Strand: Direct

Name: tnpA [H]

Synonym: lpg2069

Alternate gene names: 52842283

Gene position: 2309882-2311333 (Clockwise)

Preceding gene: 52842282

Following gene: 52842285

Centisome position: 67.98

GC content: 36.64

Gene sequence:

>1452_bases
ATGATAAAAGGGAATCAAAATAACTCATCTTCTGGATGGGCAGAGAGTGAGTTCGGAATAGTTAATTTTGGTGATAAACG
ATTAAGTAAAAGACTTCTAAAAATAGCAGATAGCTTTGCCAACTCCCCTGAATGTTCAATAAATCGAGCATGTGACGATT
GGCATCAAAGTAAAGCAGCTTATAGATTTTTTCAAAATGATGCTGTATCGGAAAGAAAAATCCTTGATAGTCATATCACT
AAAACTATTGAAAGAGCCAAGAACTATCCAACTATTTTAGCCATCCAGGATACGAGTTATATTTCTTATAAAAATCATAA
AAAGACTGAAGGATTAGGAATTATAGCAGCTAGAGTTCGCTCTAAAACAACTAATTTTCAAACTCATGGATTGGTAATGC
ATACCACATTTGCAGTAACTACAGAAGGCCTGCCTATAGGATTACTGGATCAAAAAATTAGTTCTAGACCGCTTTTAGAT
GAGACAGTAAAGGAGTTGAAAAAAAGAAGTCATAATATCGCTCTTCCTATAGAGGAAAAAGAAAGTATGCGTTGGATCGA
GTCTCTCGAACACTCTAATAATTATCCGGATTTAAAAAATGCTAAGGTGGTTACTGTTTGTGATAGAGAGGCAGATATTT
ATGATTTATTTGAAGTAGCATCGACAAATCAATGTCCTTTTGTAGTGAGGGCACGTCAAGATAGAACAGTAAATAAGACA
TCAATTTACTCTAAAAAAAGTGGTGAAAAATTATGGGATTTGGTGAGTGGTTCGCCTTGTCGGGGGGAAATTCAAGTCAC
TATTCCTGCTCGAGATAATAAGCCTAAAAGAACAGCAACATTAGAAGTAAGGTTTGATCATTTTGTGATGAACCCTCCTA
AAAATAACGTGAAACGTAAAACCAGAACACTCCCTGATTTAAAACTAAATGCAGTGTATGTCATAGAACAATCTCCTCCT
CTGGGCGAAGAGCCTATGAATTGGATGTTGTTGACCAACATAGACATTAATAATTTTGAAGAGGCAGTAGAAAAAATACA
ATGGTATTGCTTAAGATGGAGGATAGAAATTTTTCACAAAATCTTAAAATCTGGTTTTAAAGTTGAAGAATGCAGGCTCG
GTGCAGCCGATAGATTAGTTCGCTTTCTTACAATAATGAGTGTCATTGCATGGCGAATTTTTTTTATCACACTAGTTGCT
AGAGAAAGCCCCGATCTTCCTTGTTCGTTCTTATTGGCTAATGAGGAATGGAACGTCTTGTATACCAAAATACATCATAC
AAAACACTATCCTGAAACACCACCCACAATAAAAGAAGCCGTGAAATGGATAGCTCAGCTAGGCGGCTTTTTAGCCCGTA
AAAACGATGGGGAACCTGGTCCTATAACATTGTGGAGAGGATGGAAAAGATTAGTCGACCTTGCGGAAGGTTGGAATCTT
GCTCTTTCTTAG

Upstream 100 bases:

>100_bases
TACTATTACCCATAAGTCTATAAATTATAAGAAAAACTTTTTCTTTAATTTAACTCTCTGTTATAAATAAGGGCAGTATT
TTGACTGATAATGAGAGCAA

Downstream 100 bases:

>100_bases
TTATGGGTAATAGTAAGCCTAAGAACGCAGCATGCGACTTTCACCGCACTACGCTCAAGCCTTTCTGAAGCTATTCACCC
AGCAGGTATTCGCTACCAAT

Product: transposase Tn5

Products: NA

Alternate protein names: Tnp [H]

Number of amino acids: Translated: 483; Mature: 483

Protein sequence:

>483_residues
MIKGNQNNSSSGWAESEFGIVNFGDKRLSKRLLKIADSFANSPECSINRACDDWHQSKAAYRFFQNDAVSERKILDSHIT
KTIERAKNYPTILAIQDTSYISYKNHKKTEGLGIIAARVRSKTTNFQTHGLVMHTTFAVTTEGLPIGLLDQKISSRPLLD
ETVKELKKRSHNIALPIEEKESMRWIESLEHSNNYPDLKNAKVVTVCDREADIYDLFEVASTNQCPFVVRARQDRTVNKT
SIYSKKSGEKLWDLVSGSPCRGEIQVTIPARDNKPKRTATLEVRFDHFVMNPPKNNVKRKTRTLPDLKLNAVYVIEQSPP
LGEEPMNWMLLTNIDINNFEEAVEKIQWYCLRWRIEIFHKILKSGFKVEECRLGAADRLVRFLTIMSVIAWRIFFITLVA
RESPDLPCSFLLANEEWNVLYTKIHHTKHYPETPPTIKEAVKWIAQLGGFLARKNDGEPGPITLWRGWKRLVDLAEGWNL
ALS

Sequences:

>Translated_483_residues
MIKGNQNNSSSGWAESEFGIVNFGDKRLSKRLLKIADSFANSPECSINRACDDWHQSKAAYRFFQNDAVSERKILDSHIT
KTIERAKNYPTILAIQDTSYISYKNHKKTEGLGIIAARVRSKTTNFQTHGLVMHTTFAVTTEGLPIGLLDQKISSRPLLD
ETVKELKKRSHNIALPIEEKESMRWIESLEHSNNYPDLKNAKVVTVCDREADIYDLFEVASTNQCPFVVRARQDRTVNKT
SIYSKKSGEKLWDLVSGSPCRGEIQVTIPARDNKPKRTATLEVRFDHFVMNPPKNNVKRKTRTLPDLKLNAVYVIEQSPP
LGEEPMNWMLLTNIDINNFEEAVEKIQWYCLRWRIEIFHKILKSGFKVEECRLGAADRLVRFLTIMSVIAWRIFFITLVA
RESPDLPCSFLLANEEWNVLYTKIHHTKHYPETPPTIKEAVKWIAQLGGFLARKNDGEPGPITLWRGWKRLVDLAEGWNL
ALS
>Mature_483_residues
MIKGNQNNSSSGWAESEFGIVNFGDKRLSKRLLKIADSFANSPECSINRACDDWHQSKAAYRFFQNDAVSERKILDSHIT
KTIERAKNYPTILAIQDTSYISYKNHKKTEGLGIIAARVRSKTTNFQTHGLVMHTTFAVTTEGLPIGLLDQKISSRPLLD
ETVKELKKRSHNIALPIEEKESMRWIESLEHSNNYPDLKNAKVVTVCDREADIYDLFEVASTNQCPFVVRARQDRTVNKT
SIYSKKSGEKLWDLVSGSPCRGEIQVTIPARDNKPKRTATLEVRFDHFVMNPPKNNVKRKTRTLPDLKLNAVYVIEQSPP
LGEEPMNWMLLTNIDINNFEEAVEKIQWYCLRWRIEIFHKILKSGFKVEECRLGAADRLVRFLTIMSVIAWRIFFITLVA
RESPDLPCSFLLANEEWNVLYTKIHHTKHYPETPPTIKEAVKWIAQLGGFLARKNDGEPGPITLWRGWKRLVDLAEGWNL
ALS

Specific function: Mediates transposition of transposon Tn5 by a 'cut and paste' mechanism. First, the monomeric transposase binds the 19 bp inverted DNA repeats flanking the transposon. Then, dimerization of the DNA-bound transposase creates a synaptic DNA complex. After n

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transposase 11 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012337
- InterPro:   IPR002559
- InterPro:   IPR003201
- InterPro:   IPR014737
- InterPro:   IPR014736
- InterPro:   IPR014735 [H]

Pfam domain/function: PF01609 Transposase_11; PF02281 Transposase_Tn5 [H]

EC number: NA

Molecular weight: Translated: 55443; Mature: 55443

Theoretical pI: Translated: 9.47; Mature: 9.47

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKGNQNNSSSGWAESEFGIVNFGDKRLSKRLLKIADSFANSPECSINRACDDWHQSKAA
CCCCCCCCCCCCCCCCCCCEEECCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHH
YRFFQNDAVSERKILDSHITKTIERAKNYPTILAIQDTSYISYKNHKKTEGLGIIAARVR
HHHHHCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEECCCEEEECCCCCCCCCEEEEEHHH
SKTTNFQTHGLVMHTTFAVTTEGLPIGLLDQKISSRPLLDETVKELKKRSHNIALPIEEK
CCCCCCEECCEEEEEEEEEEECCCCEEHHHHHHCCCCCHHHHHHHHHHCCCCEEECCCCH
ESMRWIESLEHSNNYPDLKNAKVVTVCDREADIYDLFEVASTNQCPFVVRARQDRTVNKT
HHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCHHHHHHHHCCCCCCEEEEECCCCCCCHH
SIYSKKSGEKLWDLVSGSPCRGEIQVTIPARDNKPKRTATLEVRFDHFVMNPPKNNVKRK
HCCCCCCCHHHHHHHCCCCCCCEEEEEEECCCCCCCCEEEEEEEEEEEEECCCCHHHHHH
TRTLPDLKLNAVYVIEQSPPLGEEPMNWMLLTNIDINNFEEAVEKIQWYCLRWRIEIFHK
HHCCCCCEEEEEEEEECCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHH
ILKSGFKVEECRLGAADRLVRFLTIMSVIAWRIFFITLVARESPDLPCSFLLANEEWNVL
HHHCCCCEEHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCEE
YTKIHHTKHYPETPPTIKEAVKWIAQLGGFLARKNDGEPGPITLWRGWKRLVDLAEGWNL
EEEEECCCCCCCCCHHHHHHHHHHHHHHHHHEECCCCCCCCEEHHHHHHHHHHHHCCCCC
ALS
CCC
>Mature Secondary Structure
MIKGNQNNSSSGWAESEFGIVNFGDKRLSKRLLKIADSFANSPECSINRACDDWHQSKAA
CCCCCCCCCCCCCCCCCCCEEECCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHH
YRFFQNDAVSERKILDSHITKTIERAKNYPTILAIQDTSYISYKNHKKTEGLGIIAARVR
HHHHHCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEECCCEEEECCCCCCCCCEEEEEHHH
SKTTNFQTHGLVMHTTFAVTTEGLPIGLLDQKISSRPLLDETVKELKKRSHNIALPIEEK
CCCCCCEECCEEEEEEEEEEECCCCEEHHHHHHCCCCCHHHHHHHHHHCCCCEEECCCCH
ESMRWIESLEHSNNYPDLKNAKVVTVCDREADIYDLFEVASTNQCPFVVRARQDRTVNKT
HHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCHHHHHHHHCCCCCCEEEEECCCCCCCHH
SIYSKKSGEKLWDLVSGSPCRGEIQVTIPARDNKPKRTATLEVRFDHFVMNPPKNNVKRK
HCCCCCCCHHHHHHHCCCCCCCEEEEEEECCCCCCCCEEEEEEEEEEEEECCCCHHHHHH
TRTLPDLKLNAVYVIEQSPPLGEEPMNWMLLTNIDINNFEEAVEKIQWYCLRWRIEIFHK
HHCCCCCEEEEEEEEECCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHH
ILKSGFKVEECRLGAADRLVRFLTIMSVIAWRIFFITLVARESPDLPCSFLLANEEWNVL
HHHCCCCEEHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCEE
YTKIHHTKHYPETPPTIKEAVKWIAQLGGFLARKNDGEPGPITLWRGWKRLVDLAEGWNL
EEEEECCCCCCCCCHHHHHHHHHHHHHHHHHEECCCCCCCCEEHHHHHHHHHHHHCCCCC
ALS
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 6260374; 6271452; 7867940; 6291786; 10884228; 12367522; 11896402 [H]