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The map label for this gene is ywjB [H]

Identifier: 52842205

GI number: 52842205

Start: 2229735

End: 2230280

Strand: Direct

Name: ywjB [H]

Synonym: lpg1988

Alternate gene names: 52842205

Gene position: 2229735-2230280 (Clockwise)

Preceding gene: 52842201

Following gene: 52842206

Centisome position: 65.62

GC content: 37.55

Gene sequence:

>546_bases
ATGAAACCTAAAATTTCAGTATTTATTGCAACAAGTCTCGACGGTTATATTGCAAGGAATGATGGCTCAATCGATTGGCT
TATAGAAGCAAATTCTCTCGCCTCTCCTGGAGAGGATTGTGGATATCGATCATTTATTGCCACCATAGATACGATAATTA
TGGGTCGATATTCCTATGAAAAAGTTATTACATTTGATGAATGGCCATATGCTTCCATACCGGTAATAGTACTGAGCTCA
AAACCCATACAGATACCAGAACATTTGAGACATATCATTTCAGTTTCTAACCAGAGCCCTATAGAATTAGCTAGCGAATT
GGCTCATTATGGCATTCAACACGTATACCTTGATGGCGGGATTACTATCCAGAGATTCCTTCAAAATAATCTGATTGATG
AGATAACCATCACTATGATACCTGTTTTGATCGGTTCTGGCCGCCCTTTATTTGGTTTTCTTGAGAATGATATTAAACTC
AAACACTTGTCAACCACTAGCTATCCAGGTGGTTTTGTCCAAATTAAATACCATATTGGTGAATAG

Upstream 100 bases:

>100_bases
CCATGTTGAACAAGATAAATTTTCATCTCACCCTTTTAATTCATTAGCTAATTTATTAAAGTGTAGACTCATTTGAAATA
ACAGATAAGAAAAGCTTGTA

Downstream 100 bases:

>100_bases
CCAGATACTTTAGTCCTGTTTACTCTGTAATTGTAATGCAGCATGCAATTGCTATGTTATGATGATATAGTGCCAATTTA
TCAGTAACAGGATACGAAAT

Product: dihydrofolate reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 181; Mature: 181

Protein sequence:

>181_residues
MKPKISVFIATSLDGYIARNDGSIDWLIEANSLASPGEDCGYRSFIATIDTIIMGRYSYEKVITFDEWPYASIPVIVLSS
KPIQIPEHLRHIISVSNQSPIELASELAHYGIQHVYLDGGITIQRFLQNNLIDEITITMIPVLIGSGRPLFGFLENDIKL
KHLSTTSYPGGFVQIKYHIGE

Sequences:

>Translated_181_residues
MKPKISVFIATSLDGYIARNDGSIDWLIEANSLASPGEDCGYRSFIATIDTIIMGRYSYEKVITFDEWPYASIPVIVLSS
KPIQIPEHLRHIISVSNQSPIELASELAHYGIQHVYLDGGITIQRFLQNNLIDEITITMIPVLIGSGRPLFGFLENDIKL
KHLSTTSYPGGFVQIKYHIGE
>Mature_181_residues
MKPKISVFIATSLDGYIARNDGSIDWLIEANSLASPGEDCGYRSFIATIDTIIMGRYSYEKVITFDEWPYASIPVIVLSS
KPIQIPEHLRHIISVSNQSPIELASELAHYGIQHVYLDGGITIQRFLQNNLIDEITITMIPVLIGSGRPLFGFLENDIKL
KHLSTTSYPGGFVQIKYHIGE

Specific function: Unknown

COG id: COG0262

COG function: function code H; Dihydrofolate reductase

Gene ontology:

Cell location: Membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: To B.subtilis yyaP [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002734 [H]

Pfam domain/function: PF01872 RibD_C [H]

EC number: NA

Molecular weight: Translated: 20212; Mature: 20212

Theoretical pI: Translated: 5.53; Mature: 5.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKPKISVFIATSLDGYIARNDGSIDWLIEANSLASPGEDCGYRSFIATIDTIIMGRYSYE
CCCEEEEEEEECCCCEEEECCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHCCCCCE
KVITFDEWPYASIPVIVLSSKPIQIPEHLRHIISVSNQSPIELASELAHYGIQHVYLDGG
EEEEECCCCCCCCCEEEECCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHCCEEEEEECCC
ITIQRFLQNNLIDEITITMIPVLIGSGRPLFGFLENDIKLKHLSTTSYPGGFVQIKYHIG
CHHHHHHHHCCHHHHHHHEEEEHHCCCCCEEEEECCCEEEEEEECCCCCCCEEEEEEEEC
E
C
>Mature Secondary Structure
MKPKISVFIATSLDGYIARNDGSIDWLIEANSLASPGEDCGYRSFIATIDTIIMGRYSYE
CCCEEEEEEEECCCCEEEECCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHCCCCCE
KVITFDEWPYASIPVIVLSSKPIQIPEHLRHIISVSNQSPIELASELAHYGIQHVYLDGG
EEEEECCCCCCCCCEEEECCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHCCEEEEEECCC
ITIQRFLQNNLIDEITITMIPVLIGSGRPLFGFLENDIKLKHLSTTSYPGGFVQIKYHIG
CHHHHHHHHCCHHHHHHHEEEEHHCCCCCEEEEECCCEEEEEEECCCCCCCEEEEEEEEC
E
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9353933; 9384377 [H]