Click here to switch to the map view.

The map label for this gene is dtD

Identifier: 52842071

GI number: 52842071

Start: 2067054

End: 2067491

Strand: Direct

Name: dtD

Synonym: lpg1844

Alternate gene names: 52842071

Gene position: 2067054-2067491 (Clockwise)

Preceding gene: 52842070

Following gene: 52842072

Centisome position: 60.84

GC content: 37.21

Gene sequence:

>438_bases
ATGTTAACTGTATTACAAAGAGTAAAGGAAGCCAGGGTTGATATTGATGGTCAAACAGTTGGCAAAATAAATCATGGCTT
GCTGATACTTTGTGGTTTTGAACCTAAGGATTCGCTAGAAAATATTAAACGAATGCTGGATAAATGCATTAATTATCGCA
TTTTTGAAGACCCGAGTGGCAAAATGAACTTGAGTTTAAAGGATGTAAATGGCGGCTTGCTATTAGTACCACAATTTACT
CTCATGGCAGATACCCAAAAAGGATTGCGTCCAAGTTTTTCAAATGCAGCTTCTCCAGAACTCGGGCGTGAGCTTTTTGA
TAACTTATTAACTCTTGCTCAGAAATGCCACCAAAATACTCAAAGTGGTTGTTTTGGAGCGAACATGCAAGTTTATTTAT
GCAATGATGGGCCTGTGACATTTCTGTTACAATTTTAA

Upstream 100 bases:

>100_bases
TAAGAATTGTCAGAGATGCCGGTCACTCTGATAGAGAATCGGGAATTATTGATGCACTTATTTATGCCAGTAAGGACATC
TCAAAGCAGGGTCTTGATGC

Downstream 100 bases:

>100_bases
TTAGTTTTTACTGTATTAAATTTTTGTATAACCTGAATTGTCGAGCAAAATACAATCAACATTCATTATTGGAATTCATT
CCGGCCAAAAAAAAGCATGT

Product: D-tyrosyl-tRNA(Tyr) deacylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 145; Mature: 145

Protein sequence:

>145_residues
MLTVLQRVKEARVDIDGQTVGKINHGLLILCGFEPKDSLENIKRMLDKCINYRIFEDPSGKMNLSLKDVNGGLLLVPQFT
LMADTQKGLRPSFSNAASPELGRELFDNLLTLAQKCHQNTQSGCFGANMQVYLCNDGPVTFLLQF

Sequences:

>Translated_145_residues
MLTVLQRVKEARVDIDGQTVGKINHGLLILCGFEPKDSLENIKRMLDKCINYRIFEDPSGKMNLSLKDVNGGLLLVPQFT
LMADTQKGLRPSFSNAASPELGRELFDNLLTLAQKCHQNTQSGCFGANMQVYLCNDGPVTFLLQF
>Mature_145_residues
MLTVLQRVKEARVDIDGQTVGKINHGLLILCGFEPKDSLENIKRMLDKCINYRIFEDPSGKMNLSLKDVNGGLLLVPQFT
LMADTQKGLRPSFSNAASPELGRELFDNLLTLAQKCHQNTQSGCFGANMQVYLCNDGPVTFLLQF

Specific function: Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine

COG id: COG1490

COG function: function code J; D-Tyr-tRNAtyr deacylase

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DTD family

Homologues:

Organism=Homo sapiens, GI30795227, Length=147, Percent_Identity=36.0544217687075, Blast_Score=87, Evalue=6e-18,
Organism=Escherichia coli, GI1790320, Length=144, Percent_Identity=46.5277777777778, Blast_Score=148, Evalue=2e-37,
Organism=Caenorhabditis elegans, GI115533292, Length=143, Percent_Identity=34.965034965035, Blast_Score=79, Evalue=6e-16,
Organism=Saccharomyces cerevisiae, GI6319982, Length=146, Percent_Identity=38.3561643835616, Blast_Score=107, Evalue=6e-25,
Organism=Drosophila melanogaster, GI281361569, Length=146, Percent_Identity=36.986301369863, Blast_Score=92, Evalue=1e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DTD_LEGPA (Q5X472)

Other databases:

- EMBL:   CR628336
- RefSeq:   YP_124126.1
- ProteinModelPortal:   Q5X472
- SMR:   Q5X472
- STRING:   Q5X472
- GeneID:   3119587
- GenomeReviews:   CR628336_GR
- KEGG:   lpp:lpp1808
- LegioList:   lpp1808
- eggNOG:   COG1490
- HOGENOM:   HBG286048
- OMA:   MKAVIQR
- ProtClustDB:   PRK05273
- BioCyc:   LPNE297246:LPP1808-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00518
- InterPro:   IPR003732
- Gene3D:   G3DSA:3.50.80.10
- PANTHER:   PTHR10472
- TIGRFAMs:   TIGR00256

Pfam domain/function: PF02580 Tyr_Deacylase; SSF69500 DTyrtRNA_deacyls

EC number: NA

Molecular weight: Translated: 16136; Mature: 16136

Theoretical pI: Translated: 7.25; Mature: 7.25

Prosite motif: NA

Important sites: ACT_SITE 80-80

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.4 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
6.9 %Cys+Met (Translated Protein)
3.4 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
6.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLTVLQRVKEARVDIDGQTVGKINHGLLILCGFEPKDSLENIKRMLDKCINYRIFEDPSG
CCHHHHHHHHHHCCCCCCEECCCCCCEEEEECCCCCHHHHHHHHHHHHHHCCEEEECCCC
KMNLSLKDVNGGLLLVPQFTLMADTQKGLRPSFSNAASPELGRELFDNLLTLAQKCHQNT
CEEEEEEECCCCEEEEECEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCC
QSGCFGANMQVYLCNDGPVTFLLQF
CCCCCCCCCEEEEECCCCEEEEEEC
>Mature Secondary Structure
MLTVLQRVKEARVDIDGQTVGKINHGLLILCGFEPKDSLENIKRMLDKCINYRIFEDPSG
CCHHHHHHHHHHCCCCCCEECCCCCCEEEEECCCCCHHHHHHHHHHHHHHCCEEEECCCC
KMNLSLKDVNGGLLLVPQFTLMADTQKGLRPSFSNAASPELGRELFDNLLTLAQKCHQNT
CEEEEEEECCCCEEEEECEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCC
QSGCFGANMQVYLCNDGPVTFLLQF
CCCCCCCCCEEEEECCCCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA