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The map label for this gene is ftsK

Identifier: 52841993

GI number: 52841993

Start: 1971563

End: 1973947

Strand: Reverse

Name: ftsK

Synonym: lpg1766

Alternate gene names: 52841993

Gene position: 1973947-1971563 (Counterclockwise)

Preceding gene: 52841998

Following gene: 52841992

Centisome position: 58.1

GC content: 41.38

Gene sequence:

>2385_bases
ATGGCAAAACAACATTCGGGAAAACAGGCTGGAATCCCTAAAAAATCCATGCCGAGCTTTATAATAAAACGCTTGTGTGA
GGGGAGTTTTATATTGATTTTGACAGGAGCTCTTTTTGTTCTCTTGTCTTTATTTACCTATTCAACCAATGATCCAGGTT
GGTCTCATGCCTCCCGTTCAGGTATGTCCGTTTCAAACTCAGGGGGACAAGTTGGTGCGTATATTGCCGATGCGCTTTAT
TTTGCATTTGGATATTTTGCTTTCTTATTACCAGTAGCATTTGTTTACATTGCCTGGGCCATTTTGAAGGATTTTCGCTC
TTTTAAAGCGTTGGACAGAATGGTTCTGTTACTGAGAACGGTTGGTTTTATCCTCATGGTTTCTGGTGGTTGTGGTTTAT
TGAGTATAAATCATCGCTTTGAAGCAGTAGATACCATTCACAGTTCAGGAGGTATTATCGGACAAACAGTTGGAAATGGT
TGGTACCAAATGCTTAACATGGAAGGCGCCACTTTACTTTTATTAGCAATGTTTCTTGTGGGAACAACCTGGCTGACTGG
ATTATCCTGGATAAAGGCAATTGAGTTAATCGGATGTTACACATTAAATCTTTTCACATTTCTTGATAAATTCATCAGAA
AAGGAATGCAAATTATTTCTGAAAATTTTAACAAAGAGAAATTAAAAACACCATTGATCAAGACCGAACAACTCCCTAAA
CCTGATAATGAAAAAAAGAAATCTGTTCCTAAATTATTCCAGGACAAGAAAGATAAAGAGCAAGAAAAAGCAACACCTGT
TTTAATTGCAAGTGAAGAAAAACCTGAAATTGTCAAACCTACCAATGAATTCAAGGAAATTCGTCCTCCTAAAACAATAA
CCCCTGGAGCTCTTCCCAGTCTGTCGTTGTTAGATAAAGGCCAACCAGGGAAGCCGATGGGAGGTTATACACATGAGGAA
TTGGAAAGTCTTTCAAGAGATGTAGAACAACACTTGCTTGATTTTGGTATTCAGGCAGATGTTGTAGCCGTTCACCCGGG
GCCAGTGGTAACCCGATTTGAATTGCAATTGGCAGCAGGGGTCAAAGTGAGCAAACTGACCGCTTTGGCAAAGGATTTGG
CTCGTTCGTTATCAGTTATTTCTGTCCGAGTTGTAGAGGTTATTCCTGGTAAAACTGTTGTGGGCCTTGAATTACCCAAT
CATTCACGCCAAGTGGTCAGGTTATCAGATGTTTTATCTGCTGACGTATATCAGCAAGCTCATTCTCCCTTATCTTTAGC
CTTGGGAGTTGATATTGGCGGGCACCCTATGGTGGTTGATTTGGCAAAAATGCCTCATCTACTGGTTGCAGGAACAACTG
GTTCTGGTAAATCAGTTGGTATTAATGCCATGATTTTAAGTATTCTTTTTAAAGCAAGTCCAGAGCAAGTGCGTTTAATT
ATGGTCGATCCCAAAATGTTGGAATTATCAGTTTATGATGGGATTCCACATTTGCTGACTCCTGTTGTTACCGACATGAA
GGAGGCAGCGAGCGCACTGCGCTGGTGTGTAGAGGAAATGGAGAGGCGTTATAGGTTAATGGCTGCGTTGGGTGTTAGGA
ATTTGGCAGGGTATAACACCAAAATTACGGAAGCGGCAGCTAATGGTCAGCCATTGTTAAATCCATTATGGAAACCCGTC
GATTCTATGGATGAAACTGCACCAGAATTGCAAGCACTGCCTTATGTAGTTGTTGTAATTGATGAACTTGCTGACATGAT
GATGGTTGTTGGCAAGAAAGTGGAGCAATTGATTGCTCGTATTGCGCAAAAAGCAAGAGCAGCAGGAATCCATATGATTC
TTGCGACACAAAGACCTTCAGTGGATGTATTAACAGGTTTAATTAAATCCAATATTCCAACAAGAATATCATTTCAGGTG
TCTTCAAAAATTGATTCGCGCACCATACTTGACCAACAAGGAGCCGAACAATTGCTCGGCCATGGTGATATGTTATATCT
GGCACCAGGAAGTGGAGCTCCTTTGCGTGTGCATGGTGCTTTTGTCGATGATAAGGAAGTTCATCGTATCGCTGATGACT
GGCGGTCAAGAGGTGAACCTGATTATGTTGATGACATCCTTAAAATGGGAAATGAAAATGGGGATGGTGCTTTCGATGAT
GATAGTGGGGGGCAATCCGTAGAAGACGATGATCCTCTTTATGATCAGGCGGTAGAATTTGTAATTCAGACACGCAAGGC
TAGTATTTCTGCGGTACAGAGAAGATTAAAAATCGGTTATAATCGCGCTGCCAGAATGATAGAGGAAATGGAGAGGACAG
GAATAGTCGGTCCATTGGATGGTGGTTATCGTGACGTATTAGTAACATCAGTGACTGAGGACTGA

Upstream 100 bases:

>100_bases
TTAAGCGATGGTGATTGCTTATGCTCATTGTCTCTGCCTTCCTTATTTTTTGTGTTAAGATGGCAAATATTATGACAAAA
ATAAAAACATTAAAATACCT

Downstream 100 bases:

>100_bases
ATATGAATAAATTGTTTCTCATTTTGTTGCTCATTTTTTCGCATGAAGTGTTTAGTCAAACTTCTGCCGAAGTACTGCAG
AGTAAATTAAATGCTATACA

Product: cell division protein FtsK

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 794; Mature: 793

Protein sequence:

>794_residues
MAKQHSGKQAGIPKKSMPSFIIKRLCEGSFILILTGALFVLLSLFTYSTNDPGWSHASRSGMSVSNSGGQVGAYIADALY
FAFGYFAFLLPVAFVYIAWAILKDFRSFKALDRMVLLLRTVGFILMVSGGCGLLSINHRFEAVDTIHSSGGIIGQTVGNG
WYQMLNMEGATLLLLAMFLVGTTWLTGLSWIKAIELIGCYTLNLFTFLDKFIRKGMQIISENFNKEKLKTPLIKTEQLPK
PDNEKKKSVPKLFQDKKDKEQEKATPVLIASEEKPEIVKPTNEFKEIRPPKTITPGALPSLSLLDKGQPGKPMGGYTHEE
LESLSRDVEQHLLDFGIQADVVAVHPGPVVTRFELQLAAGVKVSKLTALAKDLARSLSVISVRVVEVIPGKTVVGLELPN
HSRQVVRLSDVLSADVYQQAHSPLSLALGVDIGGHPMVVDLAKMPHLLVAGTTGSGKSVGINAMILSILFKASPEQVRLI
MVDPKMLELSVYDGIPHLLTPVVTDMKEAASALRWCVEEMERRYRLMAALGVRNLAGYNTKITEAAANGQPLLNPLWKPV
DSMDETAPELQALPYVVVVIDELADMMMVVGKKVEQLIARIAQKARAAGIHMILATQRPSVDVLTGLIKSNIPTRISFQV
SSKIDSRTILDQQGAEQLLGHGDMLYLAPGSGAPLRVHGAFVDDKEVHRIADDWRSRGEPDYVDDILKMGNENGDGAFDD
DSGGQSVEDDDPLYDQAVEFVIQTRKASISAVQRRLKIGYNRAARMIEEMERTGIVGPLDGGYRDVLVTSVTED

Sequences:

>Translated_794_residues
MAKQHSGKQAGIPKKSMPSFIIKRLCEGSFILILTGALFVLLSLFTYSTNDPGWSHASRSGMSVSNSGGQVGAYIADALY
FAFGYFAFLLPVAFVYIAWAILKDFRSFKALDRMVLLLRTVGFILMVSGGCGLLSINHRFEAVDTIHSSGGIIGQTVGNG
WYQMLNMEGATLLLLAMFLVGTTWLTGLSWIKAIELIGCYTLNLFTFLDKFIRKGMQIISENFNKEKLKTPLIKTEQLPK
PDNEKKKSVPKLFQDKKDKEQEKATPVLIASEEKPEIVKPTNEFKEIRPPKTITPGALPSLSLLDKGQPGKPMGGYTHEE
LESLSRDVEQHLLDFGIQADVVAVHPGPVVTRFELQLAAGVKVSKLTALAKDLARSLSVISVRVVEVIPGKTVVGLELPN
HSRQVVRLSDVLSADVYQQAHSPLSLALGVDIGGHPMVVDLAKMPHLLVAGTTGSGKSVGINAMILSILFKASPEQVRLI
MVDPKMLELSVYDGIPHLLTPVVTDMKEAASALRWCVEEMERRYRLMAALGVRNLAGYNTKITEAAANGQPLLNPLWKPV
DSMDETAPELQALPYVVVVIDELADMMMVVGKKVEQLIARIAQKARAAGIHMILATQRPSVDVLTGLIKSNIPTRISFQV
SSKIDSRTILDQQGAEQLLGHGDMLYLAPGSGAPLRVHGAFVDDKEVHRIADDWRSRGEPDYVDDILKMGNENGDGAFDD
DSGGQSVEDDDPLYDQAVEFVIQTRKASISAVQRRLKIGYNRAARMIEEMERTGIVGPLDGGYRDVLVTSVTED
>Mature_793_residues
AKQHSGKQAGIPKKSMPSFIIKRLCEGSFILILTGALFVLLSLFTYSTNDPGWSHASRSGMSVSNSGGQVGAYIADALYF
AFGYFAFLLPVAFVYIAWAILKDFRSFKALDRMVLLLRTVGFILMVSGGCGLLSINHRFEAVDTIHSSGGIIGQTVGNGW
YQMLNMEGATLLLLAMFLVGTTWLTGLSWIKAIELIGCYTLNLFTFLDKFIRKGMQIISENFNKEKLKTPLIKTEQLPKP
DNEKKKSVPKLFQDKKDKEQEKATPVLIASEEKPEIVKPTNEFKEIRPPKTITPGALPSLSLLDKGQPGKPMGGYTHEEL
ESLSRDVEQHLLDFGIQADVVAVHPGPVVTRFELQLAAGVKVSKLTALAKDLARSLSVISVRVVEVIPGKTVVGLELPNH
SRQVVRLSDVLSADVYQQAHSPLSLALGVDIGGHPMVVDLAKMPHLLVAGTTGSGKSVGINAMILSILFKASPEQVRLIM
VDPKMLELSVYDGIPHLLTPVVTDMKEAASALRWCVEEMERRYRLMAALGVRNLAGYNTKITEAAANGQPLLNPLWKPVD
SMDETAPELQALPYVVVVIDELADMMMVVGKKVEQLIARIAQKARAAGIHMILATQRPSVDVLTGLIKSNIPTRISFQVS
SKIDSRTILDQQGAEQLLGHGDMLYLAPGSGAPLRVHGAFVDDKEVHRIADDWRSRGEPDYVDDILKMGNENGDGAFDDD
SGGQSVEDDDPLYDQAVEFVIQTRKASISAVQRRLKIGYNRAARMIEEMERTGIVGPLDGGYRDVLVTSVTED

Specific function: DNA motor protein, which is both required to move DNA out of the region of the septum during cell division and for the septum formation. Tracks DNA in an ATP-dependent manner by generating positive supercoils in front of it and negative supercoils behind

COG id: COG1674

COG function: function code D; DNA segregation ATPase FtsK/SpoIIIE and related proteins

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein; Cytoplasmic side. Note=Located at the septum. The large C-terminal part of the protein is cytoplasmic (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FtsK domain [H]

Homologues:

Organism=Escherichia coli, GI1787117, Length=500, Percent_Identity=64.2, Blast_Score=620, Evalue=1e-178,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR018541
- InterPro:   IPR002543 [H]

Pfam domain/function: PF09397 Ftsk_gamma; PF01580 FtsK_SpoIIIE [H]

EC number: NA

Molecular weight: Translated: 86883; Mature: 86752

Theoretical pI: Translated: 6.84; Mature: 6.84

Prosite motif: PS50901 FTSK

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CCCHHEEEEECCCC
>Mature Secondary Structure 
AKQHSGKQAGIPKKSMPSFIIKRLCEGSFILILTGALFVLLSLFTYSTNDPGWSHASRS
CCCCCCCCCCCCCCCCHHHHHHHHCCCCEEHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
GMSVSNSGGQVGAYIADALYFAFGYFAFLLPVAFVYIAWAILKDFRSFKALDRMVLLLRT
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VGFILMVSGGCGLLSINHRFEAVDTIHSSGGIIGQTVGNGWYQMLNMEGATLLLLAMFLV
HHHHEEECCCCCEEEECCCHHHHHHHHHCCCEEEEHHCCHHHHHHCCCCHHHHHHHHHHH
GTTWLTGLSWIKAIELIGCYTLNLFTFLDKFIRKGMQIISENFNKEKLKTPLIKTEQLPK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCCCCCC
PDNEKKKSVPKLFQDKKDKEQEKATPVLIASEEKPEIVKPTNEFKEIRPPKTITPGALPS
CCCHHHHHHHHHHHCCHHHHHHHCCCEEEECCCCCCCCCCCHHHHHCCCCCCCCCCCCCC
LSLLDKGQPGKPMGGYTHEELESLSRDVEQHLLDFGIQADVVAVHPGPVVTRFELQLAAG
CHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCEEEEEEEEHHCC
VKVSKLTALAKDLARSLSVISVRVVEVIPGKTVVGLELPNHSRQVVRLSDVLSADVYQQA
CHHHHHHHHHHHHHHHHHHHHEEEEEECCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHH
HSPLSLALGVDIGGHPMVVDLAKMPHLLVAGTTGSGKSVGINAMILSILFKASPEQVRLI
CCCEEEEEECCCCCCCCEEEHHHCCEEEEEECCCCCCCCCHHHHHHHHHHHCCCCCEEEE
MVDPKMLELSVYDGIPHLLTPVVTDMKEAASALRWCVEEMERRYRLMAALGVRNLAGYNT
EECCCEEEEEHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
KITEAAANGQPLLNPLWKPVDSMDETAPELQALPYVVVVIDELADMMMVVGKKVEQLIAR
CHHHHCCCCCCCHHHHHCCHHHHHHCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHH
IAQKARAAGIHMILATQRPSVDVLTGLIKSNIPTRISFQVSSKIDSRTILDQQGAEQLLG
HHHHHHHCCEEEEEECCCCCHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHCCHHHHHC
HGDMLYLAPGSGAPLRVHGAFVDDKEVHRIADDWRSRGEPDYVDDILKMGNENGDGAFDD
CCCEEEEECCCCCCEEEEECCCCCHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCCCC
DSGGQSVEDDDPLYDQAVEFVIQTRKASISAVQRRLKIGYNRAARMIEEMERTGIVGPLD
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
GGYRDVLVTSVTED
CCCHHEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8237209; 12704232 [H]