BacMap

Definition	Legionella pneumophila subsp. pneumophila str. Philadelphia 1 chromosome, complete genome.
Accession	NC_002942
Length	3,397,754

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The map label for this gene is astD

Identifier: 52841935

GI number: 52841935

Start: 1902841

End: 1904331

Strand: Direct

Name: astD

Synonym: lpg1707

Alternate gene names: 52841935

Gene position: 1902841-1904331 (Clockwise)

Preceding gene: 52841934

Following gene: 52841936

Centisome position: 56.0

GC content: 42.59

Gene sequence:

>1491_bases
ATGATGTCTAAATTACAAATCATACAGAGTAAAGGCCAATATATTAATGGAGAATGGATAAAGGGAAATGGTCTCATTCT
GGAGTCTACAAACCCCGCCTCCGGAACTTTGCTTTGGCAAGGGAATAATGCTACAGATGAAGAAATTGCAAACGCTTGTT
ACGTTGCGCATCGCGCACTGAAATCCTGGGCTAATACCAGTTTTGAGGAAAGGGCTCGTTACACTAAGGCTTTTGTGGAA
CAAGTAGAAAAAAATCGTGAGCAACTGGCACGACTTATTTCATTAGAAACAGGAAAGCCATTATGGGAATCTCAAACTGA
AGTCAGCTCAGTAATTGGCAAAGTAAATTTGTCAATTCAGGCTTATCAAGAAAGAACCTGGCCAAAACAAACTGAAACTG
CAGAAGCTAATGCCTGCCTCCGTTTTAAACCGCATGGTATTGTTGTAGTATTAGGCGCGTTTAATTTCCCTGCCCATTTA
AGCAATGGACACATTGTCCCTGCCCTCCTTGCAGGGAACACGGTATTGTATAAACCAAGTGAACATACTCCAGCAGTAGC
GGAATTGATCATCCAATGTTGGCACGATAGCGGCTTACCTCCCGGAGTTATCAATTGTCTACAGGGTAATGCAAATTGTG
GAAATACCCTATTGTCTCAAGATATTCAAGGCGTCTATTTTACCGGGAGTTATGCAACAGGGTTGCGTATACACCAACAA
TTCTGTAATAGACCCGAAGTTATTTTAGCTTTGGAAATGGGCGGAAATAACCCTTTAGTCATCGATGAAGTGAAAGACAT
TGATGCAGCTGTATACCATACAATCCTTTCAACTATGATCACTGCAGGACAACGTTGCACATGTGCGAGACGAATTATAA
TTCCTGACTCCCAGACAGGCGATCTATTTTTAGAACGCTTTGCCAAGGCTTGTAAATTAATGCGAATTGGATCCTTTGAT
AGTCAGCCAGAGCCTTTTATTGGGCCTGTTATTAGCCATGTTCAAGCATTAAAACATCTACACGCTCAGAAGCAACTAAT
CGAAATGGGGGGTGAAATCATTCTGCCGATGTCGCTTCTTCTTGAGTACACGGGACTTGTTTCTCCTGGCATTATTGATA
TGACTCGCGCCAAGAACCCGCCAGATGAAGAGATTTTTGCGCCATTTGCACAAATTTACCGTTATAATCACTTTGATGAG
GCAATTCAATTAGCGAATCAGACACGTTATGGTTTGTCAGCAGGCTTACTCAGCGATAATAAAGACCATTATCAGCAGTT
TTATCAAAATATTCGTGCCGGACTAATCAATTGGAACAGACCAACCACGGGTGCTGCCAGTAGCCTTCCATTTGGTGGTG
TCGGATGCAGTGGAAATCATAGACCAAGCGCCTATTTTGCTGCTGATTATTGTGCTTATCCTGTAGCAAGCATGGAGCAA
CCTCTGTTAACAACTCCAGTGCAACGATTGCCAGGTCTGGTATTGGAGTAA

Upstream 100 bases:

>100_bases
AGCAAGGAAACAGCAAAATTGCTTGATGTAAAACAAGGAGACAGTCTACGTATATCACCCATACGTACAGAAGATACTCC
ACCATTGTAACCAAGGAATA

Downstream 100 bases:

>100_bases
TTATTATGAATGTTTATGAATTGAATATGGATGGGCTTGTTGGTCAAACTCATCATTACGCAGGGCTCTCCTCGGGTAAT
ATAGCTTCTACAAATAATGC

Product: succinylglutamic semialdehyde dehydrogenase

Products: NA

Alternate protein names: Succinylglutamic semialdehyde dehydrogenase; SGSD

Number of amino acids: Translated: 496; Mature: 496

Protein sequence:

>496_residues
MMSKLQIIQSKGQYINGEWIKGNGLILESTNPASGTLLWQGNNATDEEIANACYVAHRALKSWANTSFEERARYTKAFVE
QVEKNREQLARLISLETGKPLWESQTEVSSVIGKVNLSIQAYQERTWPKQTETAEANACLRFKPHGIVVVLGAFNFPAHL
SNGHIVPALLAGNTVLYKPSEHTPAVAELIIQCWHDSGLPPGVINCLQGNANCGNTLLSQDIQGVYFTGSYATGLRIHQQ
FCNRPEVILALEMGGNNPLVIDEVKDIDAAVYHTILSTMITAGQRCTCARRIIIPDSQTGDLFLERFAKACKLMRIGSFD
SQPEPFIGPVISHVQALKHLHAQKQLIEMGGEIILPMSLLLEYTGLVSPGIIDMTRAKNPPDEEIFAPFAQIYRYNHFDE
AIQLANQTRYGLSAGLLSDNKDHYQQFYQNIRAGLINWNRPTTGAASSLPFGGVGCSGNHRPSAYFAADYCAYPVASMEQ
PLLTTPVQRLPGLVLE

Sequences:

>Translated_496_residues
MMSKLQIIQSKGQYINGEWIKGNGLILESTNPASGTLLWQGNNATDEEIANACYVAHRALKSWANTSFEERARYTKAFVE
QVEKNREQLARLISLETGKPLWESQTEVSSVIGKVNLSIQAYQERTWPKQTETAEANACLRFKPHGIVVVLGAFNFPAHL
SNGHIVPALLAGNTVLYKPSEHTPAVAELIIQCWHDSGLPPGVINCLQGNANCGNTLLSQDIQGVYFTGSYATGLRIHQQ
FCNRPEVILALEMGGNNPLVIDEVKDIDAAVYHTILSTMITAGQRCTCARRIIIPDSQTGDLFLERFAKACKLMRIGSFD
SQPEPFIGPVISHVQALKHLHAQKQLIEMGGEIILPMSLLLEYTGLVSPGIIDMTRAKNPPDEEIFAPFAQIYRYNHFDE
AIQLANQTRYGLSAGLLSDNKDHYQQFYQNIRAGLINWNRPTTGAASSLPFGGVGCSGNHRPSAYFAADYCAYPVASMEQ
PLLTTPVQRLPGLVLE
>Mature_496_residues
MMSKLQIIQSKGQYINGEWIKGNGLILESTNPASGTLLWQGNNATDEEIANACYVAHRALKSWANTSFEERARYTKAFVE
QVEKNREQLARLISLETGKPLWESQTEVSSVIGKVNLSIQAYQERTWPKQTETAEANACLRFKPHGIVVVLGAFNFPAHL
SNGHIVPALLAGNTVLYKPSEHTPAVAELIIQCWHDSGLPPGVINCLQGNANCGNTLLSQDIQGVYFTGSYATGLRIHQQ
FCNRPEVILALEMGGNNPLVIDEVKDIDAAVYHTILSTMITAGQRCTCARRIIIPDSQTGDLFLERFAKACKLMRIGSFD
SQPEPFIGPVISHVQALKHLHAQKQLIEMGGEIILPMSLLLEYTGLVSPGIIDMTRAKNPPDEEIFAPFAQIYRYNHFDE
AIQLANQTRYGLSAGLLSDNKDHYQQFYQNIRAGLINWNRPTTGAASSLPFGGVGCSGNHRPSAYFAADYCAYPVASMEQ
PLLTTPVQRLPGLVLE

Specific function: Catalyzes the NAD-dependent reduction of succinylglutamate semialdehyde into succinylglutamate

COG id: COG1012

COG function: function code C; NAD-dependent aldehyde dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldehyde dehydrogenase family. AstD subfamily

Homologues:

Organism=Homo sapiens, GI12007648, Length=478, Percent_Identity=28.4518828451883, Blast_Score=174, Evalue=2e-43,
Organism=Homo sapiens, GI25777730, Length=463, Percent_Identity=27.8617710583153, Blast_Score=163, Evalue=3e-40,
Organism=Homo sapiens, GI115387104, Length=459, Percent_Identity=27.0152505446623, Blast_Score=161, Evalue=2e-39,
Organism=Homo sapiens, GI25777724, Length=472, Percent_Identity=29.6610169491525, Blast_Score=153, Evalue=3e-37,
Organism=Homo sapiens, GI153266822, Length=468, Percent_Identity=26.4957264957265, Blast_Score=152, Evalue=5e-37,
Organism=Homo sapiens, GI25777732, Length=466, Percent_Identity=26.3948497854077, Blast_Score=147, Evalue=2e-35,
Organism=Homo sapiens, GI21361176, Length=481, Percent_Identity=28.8981288981289, Blast_Score=144, Evalue=2e-34,
Organism=Homo sapiens, GI188035924, Length=465, Percent_Identity=25.3763440860215, Blast_Score=141, Evalue=1e-33,
Organism=Homo sapiens, GI310128103, Length=465, Percent_Identity=25.3763440860215, Blast_Score=141, Evalue=1e-33,
Organism=Homo sapiens, GI310128093, Length=465, Percent_Identity=25.3763440860215, Blast_Score=141, Evalue=2e-33,
Organism=Homo sapiens, GI25777728, Length=412, Percent_Identity=30.3398058252427, Blast_Score=137, Evalue=2e-32,
Organism=Homo sapiens, GI25952152, Length=470, Percent_Identity=25.9574468085106, Blast_Score=135, Evalue=8e-32,
Organism=Homo sapiens, GI310128091, Length=398, Percent_Identity=26.3819095477387, Blast_Score=126, Evalue=5e-29,
Organism=Homo sapiens, GI21614513, Length=468, Percent_Identity=25, Blast_Score=125, Evalue=1e-28,
Organism=Homo sapiens, GI11095441, Length=443, Percent_Identity=25.0564334085779, Blast_Score=124, Evalue=2e-28,
Organism=Homo sapiens, GI4507229, Length=473, Percent_Identity=26.215644820296, Blast_Score=123, Evalue=3e-28,
Organism=Homo sapiens, GI238814322, Length=473, Percent_Identity=26.4270613107822, Blast_Score=122, Evalue=7e-28,
Organism=Homo sapiens, GI25777726, Length=472, Percent_Identity=26.4830508474576, Blast_Score=118, Evalue=1e-26,
Organism=Homo sapiens, GI25777721, Length=486, Percent_Identity=25.9259259259259, Blast_Score=115, Evalue=1e-25,
Organism=Homo sapiens, GI206597441, Length=423, Percent_Identity=26.7139479905437, Blast_Score=108, Evalue=2e-23,
Organism=Homo sapiens, GI206597439, Length=423, Percent_Identity=26.7139479905437, Blast_Score=108, Evalue=2e-23,
Organism=Homo sapiens, GI22907049, Length=423, Percent_Identity=26.7139479905437, Blast_Score=108, Evalue=2e-23,
Organism=Homo sapiens, GI310128087, Length=464, Percent_Identity=23.9224137931034, Blast_Score=104, Evalue=2e-22,
Organism=Homo sapiens, GI25777736, Length=341, Percent_Identity=28.7390029325513, Blast_Score=102, Evalue=8e-22,
Organism=Homo sapiens, GI25777734, Length=341, Percent_Identity=28.7390029325513, Blast_Score=102, Evalue=8e-22,
Organism=Homo sapiens, GI238859541, Length=340, Percent_Identity=28.8235294117647, Blast_Score=102, Evalue=8e-22,
Organism=Homo sapiens, GI4502043, Length=413, Percent_Identity=26.1501210653753, Blast_Score=101, Evalue=1e-21,
Organism=Homo sapiens, GI238814371, Length=413, Percent_Identity=26.1501210653753, Blast_Score=101, Evalue=1e-21,
Organism=Homo sapiens, GI310128089, Length=284, Percent_Identity=26.4084507042254, Blast_Score=98, Evalue=2e-20,
Organism=Homo sapiens, GI301500698, Length=269, Percent_Identity=29.368029739777, Blast_Score=98, Evalue=2e-20,
Organism=Homo sapiens, GI73466520, Length=394, Percent_Identity=24.8730964467005, Blast_Score=97, Evalue=4e-20,
Organism=Homo sapiens, GI4557303, Length=394, Percent_Identity=24.8730964467005, Blast_Score=97, Evalue=4e-20,
Organism=Homo sapiens, GI310128095, Length=304, Percent_Identity=25.3289473684211, Blast_Score=92, Evalue=1e-18,
Organism=Homo sapiens, GI71773324, Length=338, Percent_Identity=26.6272189349112, Blast_Score=89, Evalue=1e-17,
Organism=Homo sapiens, GI73695881, Length=332, Percent_Identity=25.9036144578313, Blast_Score=88, Evalue=2e-17,
Organism=Homo sapiens, GI73695879, Length=332, Percent_Identity=25.9036144578313, Blast_Score=88, Evalue=2e-17,
Organism=Homo sapiens, GI310128097, Length=243, Percent_Identity=28.3950617283951, Blast_Score=87, Evalue=4e-17,
Organism=Homo sapiens, GI310128099, Length=243, Percent_Identity=24.2798353909465, Blast_Score=69, Evalue=1e-11,
Organism=Homo sapiens, GI310128101, Length=243, Percent_Identity=24.2798353909465, Blast_Score=69, Evalue=1e-11,
Organism=Escherichia coli, GI1788042, Length=481, Percent_Identity=50.1039501039501, Blast_Score=514, Evalue=1e-147,
Organism=Escherichia coli, GI1789015, Length=470, Percent_Identity=30.4255319148936, Blast_Score=179, Evalue=4e-46,
Organism=Escherichia coli, GI1786504, Length=466, Percent_Identity=29.6137339055794, Blast_Score=166, Evalue=4e-42,
Organism=Escherichia coli, GI87081896, Length=458, Percent_Identity=29.2576419213974, Blast_Score=156, Evalue=4e-39,
Organism=Escherichia coli, GI87082295, Length=467, Percent_Identity=28.2655246252677, Blast_Score=149, Evalue=3e-37,
Organism=Escherichia coli, GI87081926, Length=454, Percent_Identity=25.5506607929515, Blast_Score=139, Evalue=5e-34,
Organism=Escherichia coli, GI1787558, Length=465, Percent_Identity=26.0215053763441, Blast_Score=134, Evalue=2e-32,
Organism=Escherichia coli, GI1787684, Length=467, Percent_Identity=24.6252676659529, Blast_Score=130, Evalue=2e-31,
Organism=Escherichia coli, GI1787250, Length=483, Percent_Identity=26.5010351966874, Blast_Score=128, Evalue=7e-31,
Organism=Escherichia coli, GI1787715, Length=474, Percent_Identity=27.0042194092827, Blast_Score=122, Evalue=6e-29,
Organism=Escherichia coli, GI1787653, Length=480, Percent_Identity=25.4166666666667, Blast_Score=88, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI115534176, Length=481, Percent_Identity=28.0665280665281, Blast_Score=163, Evalue=2e-40,
Organism=Caenorhabditis elegans, GI25143874, Length=448, Percent_Identity=29.0178571428571, Blast_Score=161, Evalue=6e-40,
Organism=Caenorhabditis elegans, GI25143876, Length=448, Percent_Identity=29.0178571428571, Blast_Score=161, Evalue=6e-40,
Organism=Caenorhabditis elegans, GI17551164, Length=477, Percent_Identity=27.4633123689727, Blast_Score=150, Evalue=1e-36,
Organism=Caenorhabditis elegans, GI133930964, Length=473, Percent_Identity=26.4270613107822, Blast_Score=144, Evalue=1e-34,
Organism=Caenorhabditis elegans, GI71995606, Length=464, Percent_Identity=26.2931034482759, Blast_Score=143, Evalue=2e-34,
Organism=Caenorhabditis elegans, GI17562198, Length=500, Percent_Identity=26, Blast_Score=135, Evalue=4e-32,
Organism=Caenorhabditis elegans, GI17534119, Length=464, Percent_Identity=25.2155172413793, Blast_Score=134, Evalue=8e-32,
Organism=Caenorhabditis elegans, GI71995613, Length=421, Percent_Identity=26.3657957244656, Blast_Score=133, Evalue=3e-31,
Organism=Caenorhabditis elegans, GI25144435, Length=471, Percent_Identity=26.963906581741, Blast_Score=132, Evalue=4e-31,
Organism=Caenorhabditis elegans, GI71986308, Length=442, Percent_Identity=24.8868778280543, Blast_Score=126, Evalue=2e-29,
Organism=Caenorhabditis elegans, GI32564736, Length=406, Percent_Identity=26.1083743842365, Blast_Score=112, Evalue=7e-25,
Organism=Caenorhabditis elegans, GI17534447, Length=440, Percent_Identity=25, Blast_Score=90, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17564084, Length=332, Percent_Identity=23.4939759036145, Blast_Score=87, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI32564151, Length=399, Percent_Identity=24.812030075188, Blast_Score=82, Evalue=7e-16,
Organism=Caenorhabditis elegans, GI115532534, Length=335, Percent_Identity=25.6716417910448, Blast_Score=82, Evalue=9e-16,
Organism=Caenorhabditis elegans, GI71990744, Length=289, Percent_Identity=25.9515570934256, Blast_Score=70, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6323821, Length=483, Percent_Identity=27.7432712215321, Blast_Score=166, Evalue=8e-42,
Organism=Saccharomyces cerevisiae, GI6319478, Length=472, Percent_Identity=28.3898305084746, Blast_Score=163, Evalue=6e-41,
Organism=Saccharomyces cerevisiae, GI6323822, Length=481, Percent_Identity=28.2744282744283, Blast_Score=162, Evalue=8e-41,
Organism=Saccharomyces cerevisiae, GI6320917, Length=460, Percent_Identity=26.9565217391304, Blast_Score=161, Evalue=2e-40,
Organism=Saccharomyces cerevisiae, GI6324950, Length=465, Percent_Identity=26.2365591397849, Blast_Score=152, Evalue=9e-38,
Organism=Saccharomyces cerevisiae, GI6325196, Length=461, Percent_Identity=22.7765726681128, Blast_Score=119, Evalue=1e-27,
Organism=Saccharomyces cerevisiae, GI6321826, Length=481, Percent_Identity=26.6112266112266, Blast_Score=109, Evalue=8e-25,
Organism=Saccharomyces cerevisiae, GI6321828, Length=456, Percent_Identity=23.4649122807018, Blast_Score=105, Evalue=2e-23,
Organism=Saccharomyces cerevisiae, GI6323757, Length=327, Percent_Identity=24.7706422018349, Blast_Score=65, Evalue=2e-11,
Organism=Drosophila melanogaster, GI281362580, Length=484, Percent_Identity=28.9256198347107, Blast_Score=171, Evalue=1e-42,
Organism=Drosophila melanogaster, GI62472918, Length=484, Percent_Identity=28.9256198347107, Blast_Score=171, Evalue=1e-42,
Organism=Drosophila melanogaster, GI62472926, Length=484, Percent_Identity=28.9256198347107, Blast_Score=171, Evalue=1e-42,
Organism=Drosophila melanogaster, GI62472936, Length=484, Percent_Identity=28.9256198347107, Blast_Score=171, Evalue=1e-42,
Organism=Drosophila melanogaster, GI21356737, Length=484, Percent_Identity=28.9256198347107, Blast_Score=171, Evalue=1e-42,
Organism=Drosophila melanogaster, GI20129399, Length=470, Percent_Identity=29.5744680851064, Blast_Score=169, Evalue=5e-42,
Organism=Drosophila melanogaster, GI24666674, Length=471, Percent_Identity=27.8131634819533, Blast_Score=167, Evalue=1e-41,
Organism=Drosophila melanogaster, GI24585660, Length=468, Percent_Identity=26.9230769230769, Blast_Score=140, Evalue=3e-33,
Organism=Drosophila melanogaster, GI24650465, Length=464, Percent_Identity=27.5862068965517, Blast_Score=139, Evalue=5e-33,
Organism=Drosophila melanogaster, GI24638878, Length=471, Percent_Identity=25.4777070063694, Blast_Score=115, Evalue=6e-26,
Organism=Drosophila melanogaster, GI24638876, Length=471, Percent_Identity=25.4777070063694, Blast_Score=115, Evalue=7e-26,
Organism=Drosophila melanogaster, GI24668425, Length=453, Percent_Identity=25.8278145695364, Blast_Score=97, Evalue=3e-20,
Organism=Drosophila melanogaster, GI24668417, Length=453, Percent_Identity=25.8278145695364, Blast_Score=97, Evalue=3e-20,
Organism=Drosophila melanogaster, GI24668413, Length=453, Percent_Identity=25.8278145695364, Blast_Score=97, Evalue=3e-20,
Organism=Drosophila melanogaster, GI45552499, Length=409, Percent_Identity=25.1833740831296, Blast_Score=90, Evalue=4e-18,
Organism=Drosophila melanogaster, GI281360303, Length=409, Percent_Identity=25.1833740831296, Blast_Score=89, Evalue=5e-18,
Organism=Drosophila melanogaster, GI281360299, Length=409, Percent_Identity=25.1833740831296, Blast_Score=86, Evalue=6e-17,
Organism=Drosophila melanogaster, GI281360297, Length=409, Percent_Identity=25.1833740831296, Blast_Score=86, Evalue=6e-17,
Organism=Drosophila melanogaster, GI281360295, Length=409, Percent_Identity=25.1833740831296, Blast_Score=86, Evalue=6e-17,
Organism=Drosophila melanogaster, GI24586250, Length=409, Percent_Identity=25.1833740831296, Blast_Score=86, Evalue=6e-17,
Organism=Drosophila melanogaster, GI281360301, Length=418, Percent_Identity=24.6411483253589, Blast_Score=86, Evalue=7e-17,
Organism=Drosophila melanogaster, GI28574525, Length=344, Percent_Identity=29.0697674418605, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI28571802, Length=437, Percent_Identity=22.1967963386728, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI28571800, Length=437, Percent_Identity=22.1967963386728, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI28571798, Length=437, Percent_Identity=22.1967963386728, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI28571796, Length=437, Percent_Identity=22.1967963386728, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI28571794, Length=437, Percent_Identity=22.1967963386728, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI28571806, Length=437, Percent_Identity=22.1967963386728, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI281360293, Length=153, Percent_Identity=32.6797385620915, Blast_Score=71, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ASTD_LEGPH (Q5ZUT5)

Other databases:

- EMBL:   AE017354
- RefSeq:   YP_095734.1
- ProteinModelPortal:   Q5ZUT5
- SMR:   Q5ZUT5
- STRING:   Q5ZUT5
- GeneID:   3077778
- GenomeReviews:   AE017354_GR
- KEGG:   lpn:lpg1707
- NMPDR:   fig|272624.3.peg.537
- eggNOG:   COG1012
- HOGENOM:   HBG752218
- OMA:   KAYHART
- ProtClustDB:   PRK09457
- BioCyc:   LPNE272624:LPG1707-MONOMER
- HAMAP:   MF_01174
- InterPro:   IPR016161
- InterPro:   IPR016163
- InterPro:   IPR016160
- InterPro:   IPR016162
- InterPro:   IPR015590
- InterPro:   IPR017649
- Gene3D:   G3DSA:3.40.309.10
- Gene3D:   G3DSA:3.40.605.10
- PANTHER:   PTHR11699
- TIGRFAMs:   TIGR03240

Pfam domain/function: PF00171 Aldedh; SSF53720 Aldehyde_DH/Histidinol_DH

EC number: =1.2.1.71

Molecular weight: Translated: 54697; Mature: 54697

Theoretical pI: Translated: 6.62; Mature: 6.62

Prosite motif: PS00070 ALDEHYDE_DEHYDR_CYS; PS00687 ALDEHYDE_DEHYDR_GLU

Important sites: ACT_SITE 252-252 ACT_SITE 286-286

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMSKLQIIQSKGQYINGEWIKGNGLILESTNPASGTLLWQGNNATDEEIANACYVAHRAL
CCCHHHHHHHCCCEECCEEEECCCEEEECCCCCCCEEEECCCCCCHHHHHHHHHHHHHHH
KSWANTSFEERARYTKAFVEQVEKNREQLARLISLETGKPLWESQTEVSSVIGKVNLSIQ
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCEEEE
AYQERTWPKQTETAEANACLRFKPHGIVVVLGAFNFPAHLSNGHIVPALLAGNTVLYKPS
EHHHHCCCCCCCCCCCCCEEEECCCCEEEEEECCCCCCCCCCCCEEEEEECCCEEEECCC
EHTPAVAELIIQCWHDSGLPPGVINCLQGNANCGNTLLSQDIQGVYFTGSYATGLRIHQQ
CCCCHHHHHHHHHHHCCCCCHHHHHHHCCCCCCCHHHHHHCCCEEEEECCHHHHHHHHHH
FCNRPEVILALEMGGNNPLVIDEVKDIDAAVYHTILSTMITAGQRCTCARRIIIPDSQTG
HCCCCCEEEEEEECCCCCEEEECHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCH
DLFLERFAKACKLMRIGSFDSQPEPFIGPVISHVQALKHLHAQKQLIEMGGEIILPMSLL
HHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHH
LEYTGLVSPGIIDMTRAKNPPDEEIFAPFAQIYRYNHFDEAIQLANQTRYGLSAGLLSDN
HHHHCCCCCCCEEHHCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCC
KDHYQQFYQNIRAGLINWNRPTTGAASSLPFGGVGCSGNHRPSAYFAADYCAYPVASMEQ
HHHHHHHHHHHHHCEEECCCCCCCCCCCCCCCCCCCCCCCCCCEEEEHHHHHCCHHHCCC
PLLTTPVQRLPGLVLE
CHHHCCHHHCCCCCCC
>Mature Secondary Structure
MMSKLQIIQSKGQYINGEWIKGNGLILESTNPASGTLLWQGNNATDEEIANACYVAHRAL
CCCHHHHHHHCCCEECCEEEECCCEEEECCCCCCCEEEECCCCCCHHHHHHHHHHHHHHH
KSWANTSFEERARYTKAFVEQVEKNREQLARLISLETGKPLWESQTEVSSVIGKVNLSIQ
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCEEEE
AYQERTWPKQTETAEANACLRFKPHGIVVVLGAFNFPAHLSNGHIVPALLAGNTVLYKPS
EHHHHCCCCCCCCCCCCCEEEECCCCEEEEEECCCCCCCCCCCCEEEEEECCCEEEECCC
EHTPAVAELIIQCWHDSGLPPGVINCLQGNANCGNTLLSQDIQGVYFTGSYATGLRIHQQ
CCCCHHHHHHHHHHHCCCCCHHHHHHHCCCCCCCHHHHHHCCCEEEEECCHHHHHHHHHH
FCNRPEVILALEMGGNNPLVIDEVKDIDAAVYHTILSTMITAGQRCTCARRIIIPDSQTG
HCCCCCEEEEEEECCCCCEEEECHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCH
DLFLERFAKACKLMRIGSFDSQPEPFIGPVISHVQALKHLHAQKQLIEMGGEIILPMSLL
HHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHH
LEYTGLVSPGIIDMTRAKNPPDEEIFAPFAQIYRYNHFDEAIQLANQTRYGLSAGLLSDN
HHHHCCCCCCCEEHHCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCC
KDHYQQFYQNIRAGLINWNRPTTGAASSLPFGGVGCSGNHRPSAYFAADYCAYPVASMEQ
HHHHHHHHHHHHHCEEECCCCCCCCCCCCCCCCCCCCCCCCCCEEEEHHHHHCCHHHCCC
PLLTTPVQRLPGLVLE
CHHHCCHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA