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The map label for this gene is entS [H]

Identifier: 52841866

GI number: 52841866

Start: 1809954

End: 1811267

Strand: Direct

Name: entS [H]

Synonym: lpg1638

Alternate gene names: 52841866

Gene position: 1809954-1811267 (Clockwise)

Preceding gene: 52841865

Following gene: 52841868

Centisome position: 53.27

GC content: 39.19

Gene sequence:

>1314_bases
CTGATCTTATTAATTTCTGTACTGTTTCATCAAAAGAGCTTAAAATTCATATCTCAAAATCTTTATAATTCACCCCACTA
TAATTTACAGATTGCCAATATGAGTCATTTACTAGATTTATCCATCCTTAAAAAAAATCGCGACTTTACCTTGCTTTATT
TGGGCCAATTCATTTCATTCATAGGCACAATGATTACCAGTGTCGCCCTTCCCTATCAAATTTATCATTTGACCGAATCG
ACCATGATGGTAGGATTACTCAGCTTGGCACAATTACTGCCTCTACTGATTACTGCATTGCTTGGTGGAGTGTTTGCTGA
TCGATATAGCCGACGCGGATTACTAATCATTAGTGAATTATTACTTGCTGTTGGTTGTCTTTTTCTGGCTTTCAATTCCA
AACTGGTTAATCCAAGTGTTAGCTTGATATTTATAATAGCCTCATTAATGTCCGCCATTACAGGTTTACATAGGCCTGCT
TTTGATAGTGTGATACAACAAATCGTGAAACCAGAGGATTACAAGAAAGTAGGCGCTCTTGGCAGCTTCAAATTCAGTTT
TTGTATGATTATTGGACCAGCTGCTGCTGGCTTGATTATTGCGCAATATGGTATTGTAATCACTTATCTCATTGATTTAT
TAACCTTTATCATTTCACTTCTCAATTTGAGCTTAATGCACACCATACCCAAGCCTTTAGCCAAAGAGCATCCATCCATT
ATAGTTTCTTTGAAAGAAGGTATAGGTTTTGCTTTGCGCCGACAAGAGCTGATGGGTAGTTATTTCGTTGATTTCTTTGC
GATGGTTTTTGCTATGCCAAATGCATTGTTGCCTGCTATTGCCCAACAATTTGGAGGAGCTAAAACACTAGGACTACTTT
ATGCTGCGCCAGCTATAGGGTCGCTGATTATTTCTTTTGTTAGTGGCTGGACCGCAAAAATTACTCATGATGGAAAAGCG
ATCGCAATTGCTGCTGCTTTGTGGGGAGTGGCAATTATCGGATTTGGTCTCACCACTTCTTTGTGGTTATCTCTCTTGTT
TCTTGCTCTTGCAGGAGCATTTGATGCCATTAGTGGTATTTTCAGAAGCAGCTTATGGAATCATACCATCCCGCAAGAAT
TGAGAGGCCGCCTGTCTGGAATTGAAATGATTAGTTATTTGAGCGGCCCAAGATTGGGTGATACCAGAGCAGGCTTTGTT
GCAGCAGGTTTAGGCATACCTGCTGCATTAATATCAGGCGGTATTTTATGTATTATTGGAGTGACTGTATGCTGCTATGC
CTTGCCTAAATTTTGGAATTATCATTCAAAGTAA

Upstream 100 bases:

>100_bases
GTTAGGAAATGTTTTTAATTCAGTCGTTTAGTTTATCTAAGATTCTTCGTTAAAACATTTTTTGCCTTGATCGTGAGGTT
TTTCGTAATGCTCTTATAGT

Downstream 100 bases:

>100_bases
TTAACCACTTTACTAATCTCCAATAATAGAGGCTTTTTTATGTTGTTGCTTGGTAGTCTCATCCAAACTGGCCGCTTCCG
TTAATGCGGCTACATTTTCC

Product: drug:proton antiporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 437; Mature: 437

Protein sequence:

>437_residues
MILLISVLFHQKSLKFISQNLYNSPHYNLQIANMSHLLDLSILKKNRDFTLLYLGQFISFIGTMITSVALPYQIYHLTES
TMMVGLLSLAQLLPLLITALLGGVFADRYSRRGLLIISELLLAVGCLFLAFNSKLVNPSVSLIFIIASLMSAITGLHRPA
FDSVIQQIVKPEDYKKVGALGSFKFSFCMIIGPAAAGLIIAQYGIVITYLIDLLTFIISLLNLSLMHTIPKPLAKEHPSI
IVSLKEGIGFALRRQELMGSYFVDFFAMVFAMPNALLPAIAQQFGGAKTLGLLYAAPAIGSLIISFVSGWTAKITHDGKA
IAIAAALWGVAIIGFGLTTSLWLSLLFLALAGAFDAISGIFRSSLWNHTIPQELRGRLSGIEMISYLSGPRLGDTRAGFV
AAGLGIPAALISGGILCIIGVTVCCYALPKFWNYHSK

Sequences:

>Translated_437_residues
MILLISVLFHQKSLKFISQNLYNSPHYNLQIANMSHLLDLSILKKNRDFTLLYLGQFISFIGTMITSVALPYQIYHLTES
TMMVGLLSLAQLLPLLITALLGGVFADRYSRRGLLIISELLLAVGCLFLAFNSKLVNPSVSLIFIIASLMSAITGLHRPA
FDSVIQQIVKPEDYKKVGALGSFKFSFCMIIGPAAAGLIIAQYGIVITYLIDLLTFIISLLNLSLMHTIPKPLAKEHPSI
IVSLKEGIGFALRRQELMGSYFVDFFAMVFAMPNALLPAIAQQFGGAKTLGLLYAAPAIGSLIISFVSGWTAKITHDGKA
IAIAAALWGVAIIGFGLTTSLWLSLLFLALAGAFDAISGIFRSSLWNHTIPQELRGRLSGIEMISYLSGPRLGDTRAGFV
AAGLGIPAALISGGILCIIGVTVCCYALPKFWNYHSK
>Mature_437_residues
MILLISVLFHQKSLKFISQNLYNSPHYNLQIANMSHLLDLSILKKNRDFTLLYLGQFISFIGTMITSVALPYQIYHLTES
TMMVGLLSLAQLLPLLITALLGGVFADRYSRRGLLIISELLLAVGCLFLAFNSKLVNPSVSLIFIIASLMSAITGLHRPA
FDSVIQQIVKPEDYKKVGALGSFKFSFCMIIGPAAAGLIIAQYGIVITYLIDLLTFIISLLNLSLMHTIPKPLAKEHPSI
IVSLKEGIGFALRRQELMGSYFVDFFAMVFAMPNALLPAIAQQFGGAKTLGLLYAAPAIGSLIISFVSGWTAKITHDGKA
IAIAAALWGVAIIGFGLTTSLWLSLLFLALAGAFDAISGIFRSSLWNHTIPQELRGRLSGIEMISYLSGPRLGDTRAGFV
AAGLGIPAALISGGILCIIGVTVCCYALPKFWNYHSK

Specific function: Exports the siderophore enterobactin out of the cell [H]

COG id: COG0477

COG function: function code GEPR; Permeases of the major facilitator superfamily

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. EntS (TC 2.A.1.38) family [H]

Homologues:

Organism=Escherichia coli, GI1786806, Length=362, Percent_Identity=28.7292817679558, Blast_Score=103, Evalue=3e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR010290
- InterPro:   IPR016196 [H]

Pfam domain/function: PF05977 DUF894 [H]

EC number: NA

Molecular weight: Translated: 47350; Mature: 47350

Theoretical pI: Translated: 9.71; Mature: 9.71

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MILLISVLFHQKSLKFISQNLYNSPHYNLQIANMSHLLDLSILKKNRDFTLLYLGQFISF
CEEEHHHHHHHHHHHHHHHHHCCCCCCEEEECCHHHHHHHHHHHCCCCEEEHHHHHHHHH
IGTMITSVALPYQIYHLTESTMMVGLLSLAQLLPLLITALLGGVFADRYSRRGLLIISEL
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHH
LLAVGCLFLAFNSKLVNPSVSLIFIIASLMSAITGLHRPAFDSVIQQIVKPEDYKKVGAL
HHHHHHHHHHHCCHHCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHCCC
GSFKFSFCMIIGPAAAGLIIAQYGIVITYLIDLLTFIISLLNLSLMHTIPKPLAKEHPSI
CCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCE
IVSLKEGIGFALRRQELMGSYFVDFFAMVFAMPNALLPAIAQQFGGAKTLGLLYAAPAIG
EEEEHHCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCHHHHHHHHHHHHH
SLIISFVSGWTAKITHDGKAIAIAAALWGVAIIGFGLTTSLWLSLLFLALAGAFDAISGI
HHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FRSSLWNHTIPQELRGRLSGIEMISYLSGPRLGDTRAGFVAAGLGIPAALISGGILCIIG
HHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHCCCCHHHHHCCCHHHHHH
VTVCCYALPKFWNYHSK
HHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MILLISVLFHQKSLKFISQNLYNSPHYNLQIANMSHLLDLSILKKNRDFTLLYLGQFISF
CEEEHHHHHHHHHHHHHHHHHCCCCCCEEEECCHHHHHHHHHHHCCCCEEEHHHHHHHHH
IGTMITSVALPYQIYHLTESTMMVGLLSLAQLLPLLITALLGGVFADRYSRRGLLIISEL
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHH
LLAVGCLFLAFNSKLVNPSVSLIFIIASLMSAITGLHRPAFDSVIQQIVKPEDYKKVGAL
HHHHHHHHHHHCCHHCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHCCC
GSFKFSFCMIIGPAAAGLIIAQYGIVITYLIDLLTFIISLLNLSLMHTIPKPLAKEHPSI
CCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCE
IVSLKEGIGFALRRQELMGSYFVDFFAMVFAMPNALLPAIAQQFGGAKTLGLLYAAPAIG
EEEEHHCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCHHHHHHHHHHHHH
SLIISFVSGWTAKITHDGKAIAIAAALWGVAIIGFGLTTSLWLSLLFLALAGAFDAISGI
HHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FRSSLWNHTIPQELRGRLSGIEMISYLSGPRLGDTRAGFVAAGLGIPAALISGGILCIIG
HHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHCCCCHHHHHCCCHHHHHH
VTVCCYALPKFWNYHSK
HHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA