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The map label for this gene is moeZ [H]

Identifier: 52841799

GI number: 52841799

Start: 1735718

End: 1736857

Strand: Direct

Name: moeZ [H]

Synonym: lpg1569

Alternate gene names: 52841799

Gene position: 1735718-1736857 (Clockwise)

Preceding gene: 52841798

Following gene: 52841809

Centisome position: 51.08

GC content: 36.93

Gene sequence:

>1140_bases
ATGAATCACATAATGAATAAATCAAATTTGGCAATGAACAAATTAACCCGCTATTCTCAACAAATAAAGATGGAAGAAAT
TGGATTAGACGGACAGGAGAAACTTAAGAATTCTCGAGTATTATGCATTGGGCTTGGCGGTTTGGGTTCGCCTCTCTTAC
TTTACCTTGCTGCAGCAGGTGTCGGAGTGTTAGGGATTGTCGATGATGACATCATTGAGCTAAGTAATTTGCATAGGCAG
ATTCTTTATAATCATACCCATATTAATAAAAAAAAGGCTGTTACTGCAAAAAAGCAACTTCTGGCTATTAATCCCCTGAT
TCAAGTTGAATCTTACTCCAGTAGATTAACAGAAGAAAATGCGGCTGAGCTAATTACGCAGTATGACATCATCGCAGATG
GAACCGATAATTTTTATACGCGATATTTGATTCACAGCATTTGCTTTGAACTGGAAAAACCTTATGTGTATGCTAGTGCC
TCAGGTTTCCAAGGGTATTGCTCTATATTCCATGGGAAACAAGATCCCTGCCTCCATTGTATCTTCCCGGTTTCTGTAAG
CGATATCAATATTCCCAATTGCGAGGGAGCCGGGGTAATTGGTACTTTACCCGGGATGCTAGGTATTATTCAGGCAACAG
AAATAATCAAATGGATACTACAAATTGGCAATCCATTAAAAAAGCGTTTGCTTACTATTAACCTGTTAACAATGACCTTT
AAGAACATCATTATTTCAAGAAATCCGGATTGTGAATTCTGCATTCAGAATCAGTCAATTAGACAATTAATTAATCCTGT
TAATTGTTCAGCTCAAATTGAGCCATGCCATCATAGAATAACTCTTGATGAATTTTATCAATTATTTACGAATAATAAAA
ACATTCATCTAATTGATGTTCGTAGTACAAAGGAACATCAAATACAAAATATAGGGGGTATTGTGCTTCCTTTAGATGAG
CTGCCTCAACGCTTACATGAACTAAACCCTAATCGGCTTATTATTCTGTACTGCCAGTCGGGAACGCGAAGCAAGATGGC
GTTAGATATACTTCTCAAGGCTGGCTTTGCTTCTGTTAAATATATAGAAAATGGTTTAAAGGGAGTAACTGACAATTACA
ATAAAGACATGCCCCAATAA

Upstream 100 bases:

>100_bases
GATGTCTTAAAAACAAAAATTGATGGTGTGTCAGTGATCTCTGCCATTACAAAAGCATCAGCACCTTTAGTTGCAGCCAA
ACAATTTTTAACTCAAATGA

Downstream 100 bases:

>100_bases
TTCACCCCTCCTAAAAAGGAAGCTGAAATTAAATAAGTTTATTTTTACCTTCGGCAATATTATTTAGCAGATAAGCGAGT
CGACACCCAGCCAGAAGTAT

Product: sulfurylase ThiF

Products: NA

Alternate protein names: Sulfur carrier protein CysO adenylyltransferase; Sulfur carrier protein CysO sulfurtransferase [H]

Number of amino acids: Translated: 379; Mature: 379

Protein sequence:

>379_residues
MNHIMNKSNLAMNKLTRYSQQIKMEEIGLDGQEKLKNSRVLCIGLGGLGSPLLLYLAAAGVGVLGIVDDDIIELSNLHRQ
ILYNHTHINKKKAVTAKKQLLAINPLIQVESYSSRLTEENAAELITQYDIIADGTDNFYTRYLIHSICFELEKPYVYASA
SGFQGYCSIFHGKQDPCLHCIFPVSVSDINIPNCEGAGVIGTLPGMLGIIQATEIIKWILQIGNPLKKRLLTINLLTMTF
KNIIISRNPDCEFCIQNQSIRQLINPVNCSAQIEPCHHRITLDEFYQLFTNNKNIHLIDVRSTKEHQIQNIGGIVLPLDE
LPQRLHELNPNRLIILYCQSGTRSKMALDILLKAGFASVKYIENGLKGVTDNYNKDMPQ

Sequences:

>Translated_379_residues
MNHIMNKSNLAMNKLTRYSQQIKMEEIGLDGQEKLKNSRVLCIGLGGLGSPLLLYLAAAGVGVLGIVDDDIIELSNLHRQ
ILYNHTHINKKKAVTAKKQLLAINPLIQVESYSSRLTEENAAELITQYDIIADGTDNFYTRYLIHSICFELEKPYVYASA
SGFQGYCSIFHGKQDPCLHCIFPVSVSDINIPNCEGAGVIGTLPGMLGIIQATEIIKWILQIGNPLKKRLLTINLLTMTF
KNIIISRNPDCEFCIQNQSIRQLINPVNCSAQIEPCHHRITLDEFYQLFTNNKNIHLIDVRSTKEHQIQNIGGIVLPLDE
LPQRLHELNPNRLIILYCQSGTRSKMALDILLKAGFASVKYIENGLKGVTDNYNKDMPQ
>Mature_379_residues
MNHIMNKSNLAMNKLTRYSQQIKMEEIGLDGQEKLKNSRVLCIGLGGLGSPLLLYLAAAGVGVLGIVDDDIIELSNLHRQ
ILYNHTHINKKKAVTAKKQLLAINPLIQVESYSSRLTEENAAELITQYDIIADGTDNFYTRYLIHSICFELEKPYVYASA
SGFQGYCSIFHGKQDPCLHCIFPVSVSDINIPNCEGAGVIGTLPGMLGIIQATEIIKWILQIGNPLKKRLLTINLLTMTF
KNIIISRNPDCEFCIQNQSIRQLINPVNCSAQIEPCHHRITLDEFYQLFTNNKNIHLIDVRSTKEHQIQNIGGIVLPLDE
LPQRLHELNPNRLIILYCQSGTRSKMALDILLKAGFASVKYIENGLKGVTDNYNKDMPQ

Specific function: Catalyzes the conversion of the sulfur carrier protein CysO to CysO-thiocarboxylate. The reaction is thought to proceed in two steps:first, ATP-dependent activation of CysO as acyl- adenylate (CysO-COOAMP), followed by sulfur transfer to give CysO- thioca

COG id: COG0476

COG function: function code H; Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2

Gene ontology:

Cell location: Membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 rhodanese domain [H]

Homologues:

Organism=Homo sapiens, GI7657339, Length=333, Percent_Identity=34.2342342342342, Blast_Score=174, Evalue=9e-44,
Organism=Homo sapiens, GI4885649, Length=149, Percent_Identity=27.5167785234899, Blast_Score=78, Evalue=2e-14,
Organism=Homo sapiens, GI38045948, Length=164, Percent_Identity=32.3170731707317, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI150417996, Length=147, Percent_Identity=29.2517006802721, Blast_Score=72, Evalue=8e-13,
Organism=Homo sapiens, GI23510338, Length=182, Percent_Identity=27.4725274725275, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI23510340, Length=182, Percent_Identity=27.4725274725275, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI38045942, Length=197, Percent_Identity=26.3959390862944, Blast_Score=68, Evalue=2e-11,
Organism=Homo sapiens, GI38045944, Length=197, Percent_Identity=26.3959390862944, Blast_Score=68, Evalue=2e-11,
Organism=Escherichia coli, GI1787048, Length=250, Percent_Identity=35.6, Blast_Score=163, Evalue=2e-41,
Organism=Escherichia coli, GI87082356, Length=241, Percent_Identity=39.4190871369295, Blast_Score=156, Evalue=2e-39,
Organism=Caenorhabditis elegans, GI17540406, Length=383, Percent_Identity=32.3759791122715, Blast_Score=184, Evalue=5e-47,
Organism=Caenorhabditis elegans, GI193203301, Length=163, Percent_Identity=29.4478527607362, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI71984476, Length=180, Percent_Identity=28.3333333333333, Blast_Score=79, Evalue=3e-15,
Organism=Saccharomyces cerevisiae, GI6321903, Length=404, Percent_Identity=30.6930693069307, Blast_Score=181, Evalue=2e-46,
Organism=Saccharomyces cerevisiae, GI6320598, Length=168, Percent_Identity=34.5238095238095, Blast_Score=83, Evalue=6e-17,
Organism=Saccharomyces cerevisiae, GI6322639, Length=165, Percent_Identity=27.2727272727273, Blast_Score=69, Evalue=9e-13,
Organism=Drosophila melanogaster, GI24582879, Length=392, Percent_Identity=35.969387755102, Blast_Score=214, Evalue=8e-56,
Organism=Drosophila melanogaster, GI24660640, Length=150, Percent_Identity=29.3333333333333, Blast_Score=89, Evalue=3e-18,
Organism=Drosophila melanogaster, GI20129973, Length=204, Percent_Identity=28.4313725490196, Blast_Score=75, Evalue=1e-13,
Organism=Drosophila melanogaster, GI28573937, Length=177, Percent_Identity=28.2485875706215, Blast_Score=70, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007901
- InterPro:   IPR009036
- InterPro:   IPR016040
- InterPro:   IPR001763
- InterPro:   IPR000594 [H]

Pfam domain/function: PF05237 MoeZ_MoeB; PF00581 Rhodanese; PF00899 ThiF [H]

EC number: NA

Molecular weight: Translated: 42558; Mature: 42558

Theoretical pI: Translated: 7.71; Mature: 7.71

Prosite motif: PS50206 RHODANESE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.9 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
2.9 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNHIMNKSNLAMNKLTRYSQQIKMEEIGLDGQEKLKNSRVLCIGLGGLGSPLLLYLAAAG
CCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCEEEEECCCCCHHHHHHHHHHC
VGVLGIVDDDIIELSNLHRQILYNHTHINKKKAVTAKKQLLAINPLIQVESYSSRLTEEN
CCEEEECCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHEEECCEEEEECHHHHHCHHH
AAELITQYDIIADGTDNFYTRYLIHSICFELEKPYVYASASGFQGYCSIFHGKQDPCLHC
HHHHHHHHHEEECCCCHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHCCCCCCCEEE
IFPVSVSDINIPNCEGAGVIGTLPGMLGIIQATEIIKWILQIGNPLKKRLLTINLLTMTF
EEECEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
KNIIISRNPDCEFCIQNQSIRQLINPVNCSAQIEPCHHRITLDEFYQLFTNNKNIHLIDV
HHHHCCCCCCCCEEECCHHHHHHCCCCCCCEEECCCHHCCCHHHHHHHHCCCCCEEEEEE
RSTKEHQIQNIGGIVLPLDELPQRLHELNPNRLIILYCQSGTRSKMALDILLKAGFASVK
CCCCHHHHHHCCCEEEEHHHHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHHHHCCHHHH
YIENGLKGVTDNYNKDMPQ
HHHHCCCCCCCCCCCCCCC
>Mature Secondary Structure
MNHIMNKSNLAMNKLTRYSQQIKMEEIGLDGQEKLKNSRVLCIGLGGLGSPLLLYLAAAG
CCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCEEEEECCCCCHHHHHHHHHHC
VGVLGIVDDDIIELSNLHRQILYNHTHINKKKAVTAKKQLLAINPLIQVESYSSRLTEEN
CCEEEECCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHEEECCEEEEECHHHHHCHHH
AAELITQYDIIADGTDNFYTRYLIHSICFELEKPYVYASASGFQGYCSIFHGKQDPCLHC
HHHHHHHHHEEECCCCHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHCCCCCCCEEE
IFPVSVSDINIPNCEGAGVIGTLPGMLGIIQATEIIKWILQIGNPLKKRLLTINLLTMTF
EEECEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
KNIIISRNPDCEFCIQNQSIRQLINPVNCSAQIEPCHHRITLDEFYQLFTNNKNIHLIDV
HHHHCCCCCCCCEEECCHHHHHHCCCCCCCEEECCCHHCCCHHHHHHHHCCCCCEEEEEE
RSTKEHQIQNIGGIVLPLDELPQRLHELNPNRLIILYCQSGTRSKMALDILLKAGFASVK
CCCCHHHHHHCCCEEEEHHHHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHHHHCCHHHH
YIENGLKGVTDNYNKDMPQ
HHHHCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]