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The map label for this gene is pabB [H]

Identifier: 52841787

GI number: 52841787

Start: 1720057

End: 1721379

Strand: Reverse

Name: pabB [H]

Synonym: lpg1557

Alternate gene names: 52841787

Gene position: 1721379-1720057 (Counterclockwise)

Preceding gene: 52841793

Following gene: 52841786

Centisome position: 50.66

GC content: 37.19

Gene sequence:

>1323_bases
TTGATTGATAGTACTCTTATTACACTTGACTACCATGATTTTTCATCTGAATCCTATGAAAAATTCAGTCGTTTACCTGG
ATTTGTCCTGCTTCAGAGTACAGACAAGTCAACGGGGCGTTATGATATTTTAAGTGCTTATCCATATGAGAGGATGGTTA
TTGAGAATAATGTACATGATAAAGATTTAGTATTAACAGAATTAAAAAATAAACTAAAAATAGAGGAGTCAGAATTTGAT
CTTCCTTTTCAGGGCGGGGCCATAGGCTACGTTTCTTACGACTTTGGTTCACTCTTACATAATCATGAACAATATTCACA
AAAAGATCTGGCGCATATACCTGTTTTAAATTTCGGATTTTATGATTGGGCTATCATAGTTGATCACCATTTAAAAAAGG
CCACTTTATTTGCGAGAAATAGCCATTCTTCAACAAAAAGCGTTGTAGATAAAATAAAGAATATATTGAATGATCAACCC
ATGAAATCGGTACAATTTTCAGTTCAAGCTGAATTTTTGCCTTTAATATCAAAAGAGAACTACAGGAGCTCATTCAATGC
CATTCAACAAGCCCTGAGAGCAGGACGCTCTTATCAGGTTAATTTCACGCAACCGTTTCAAACAAAATTCACCGGGGATC
TCTGGGATATGTACCAAAGGGTTAACAAAAATAACCCTGTCCCCTATGCTGCTTTTATCAGAACTGAGGAAGCTGACATA
TTGAGCTTTTCTCCTGAGCGATTTTTACTTTATGACAACGGTGAAATGTTAACTTCGCCCATAAAAGGCACTATCCACCG
ATCGAAAGATCCTGTTGTAGATAAAAAATTAAAAGAACAGTTATTGAAATGCCCTAAAAACAAGGCTGAAAATGTCATGA
TTGTCGATTTGCTAAGAAACGATCTAGGGAAACTTGCCAAGGCTGGCAGTGTAAAGGTAATGAATCTTTGCCACATCCAG
AGCTTCAATGCAGTACATCATTTGGTTTCCGACATAAGAGCTCTATGCAAAGAGGATATTCATCCAATTGAAGCATTTTT
CTCCTGTTTTCCAGGTGGTTCAATTACCGGGGCGCCTAAATTAGAGACGATGAAAATTATCAGTGAACAGGAAACCTATA
AAAGAGGGGTCTATTGCGGTTGCATAGCCTATTTTTCACAACATGGCCGTTTCGATGCCAATATCGCGATACGTACGGTG
ACAGCCAAAGATAATGTTTTATATTTGGCAGCAGGAGGGGGAATAGTTATTGACTCCGATTGGGAAGATGAATATCGTGA
ATGTTTCACAAAAATTACTGCAATTATCAATGGAATCAAATAA

Upstream 100 bases:

>100_bases
AAGATAAAAATATACGTTTTTTATTGATAAGTTAGGTTAAAATGACCAAATGAAAAACACTGCATTTTTTCACAGCACAT
CCTTATCTTGAGGTGATAAT

Downstream 100 bases:

>100_bases
TACCCAACAGTCAATCAAAATACATTCATCAGTTATCGTTTTACATGATCTTTCCAAAGACTCGTTAATTCTCACCAGGC
GAAGTCAGATGCTTAAAAAA

Product: para-aminobenzoate synthase, component I

Products: NA

Alternate protein names: ADC synthase; Para-aminobenzoate synthase component I [H]

Number of amino acids: Translated: 440; Mature: 440

Protein sequence:

>440_residues
MIDSTLITLDYHDFSSESYEKFSRLPGFVLLQSTDKSTGRYDILSAYPYERMVIENNVHDKDLVLTELKNKLKIEESEFD
LPFQGGAIGYVSYDFGSLLHNHEQYSQKDLAHIPVLNFGFYDWAIIVDHHLKKATLFARNSHSSTKSVVDKIKNILNDQP
MKSVQFSVQAEFLPLISKENYRSSFNAIQQALRAGRSYQVNFTQPFQTKFTGDLWDMYQRVNKNNPVPYAAFIRTEEADI
LSFSPERFLLYDNGEMLTSPIKGTIHRSKDPVVDKKLKEQLLKCPKNKAENVMIVDLLRNDLGKLAKAGSVKVMNLCHIQ
SFNAVHHLVSDIRALCKEDIHPIEAFFSCFPGGSITGAPKLETMKIISEQETYKRGVYCGCIAYFSQHGRFDANIAIRTV
TAKDNVLYLAAGGGIVIDSDWEDEYRECFTKITAIINGIK

Sequences:

>Translated_440_residues
MIDSTLITLDYHDFSSESYEKFSRLPGFVLLQSTDKSTGRYDILSAYPYERMVIENNVHDKDLVLTELKNKLKIEESEFD
LPFQGGAIGYVSYDFGSLLHNHEQYSQKDLAHIPVLNFGFYDWAIIVDHHLKKATLFARNSHSSTKSVVDKIKNILNDQP
MKSVQFSVQAEFLPLISKENYRSSFNAIQQALRAGRSYQVNFTQPFQTKFTGDLWDMYQRVNKNNPVPYAAFIRTEEADI
LSFSPERFLLYDNGEMLTSPIKGTIHRSKDPVVDKKLKEQLLKCPKNKAENVMIVDLLRNDLGKLAKAGSVKVMNLCHIQ
SFNAVHHLVSDIRALCKEDIHPIEAFFSCFPGGSITGAPKLETMKIISEQETYKRGVYCGCIAYFSQHGRFDANIAIRTV
TAKDNVLYLAAGGGIVIDSDWEDEYRECFTKITAIINGIK
>Mature_440_residues
MIDSTLITLDYHDFSSESYEKFSRLPGFVLLQSTDKSTGRYDILSAYPYERMVIENNVHDKDLVLTELKNKLKIEESEFD
LPFQGGAIGYVSYDFGSLLHNHEQYSQKDLAHIPVLNFGFYDWAIIVDHHLKKATLFARNSHSSTKSVVDKIKNILNDQP
MKSVQFSVQAEFLPLISKENYRSSFNAIQQALRAGRSYQVNFTQPFQTKFTGDLWDMYQRVNKNNPVPYAAFIRTEEADI
LSFSPERFLLYDNGEMLTSPIKGTIHRSKDPVVDKKLKEQLLKCPKNKAENVMIVDLLRNDLGKLAKAGSVKVMNLCHIQ
SFNAVHHLVSDIRALCKEDIHPIEAFFSCFPGGSITGAPKLETMKIISEQETYKRGVYCGCIAYFSQHGRFDANIAIRTV
TAKDNVLYLAAGGGIVIDSDWEDEYRECFTKITAIINGIK

Specific function: Catalyzes the biosynthesis of 4-amino-4-deoxychorismate (ADC) from chorismate and glutamine [H]

COG id: COG0147

COG function: function code EH; Anthranilate/para-aminobenzoate synthases component I

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anthranilate synthase component I family [H]

Homologues:

Organism=Escherichia coli, GI1788114, Length=456, Percent_Identity=38.3771929824561, Blast_Score=316, Evalue=2e-87,
Organism=Escherichia coli, GI1787518, Length=395, Percent_Identity=28.8607594936709, Blast_Score=162, Evalue=4e-41,
Organism=Escherichia coli, GI1786809, Length=222, Percent_Identity=22.0720720720721, Blast_Score=78, Evalue=1e-15,
Organism=Saccharomyces cerevisiae, GI6320935, Length=388, Percent_Identity=30.4123711340206, Blast_Score=183, Evalue=4e-47,
Organism=Saccharomyces cerevisiae, GI6324361, Length=402, Percent_Identity=27.1144278606965, Blast_Score=124, Evalue=2e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005801
- InterPro:   IPR019999
- InterPro:   IPR006805
- InterPro:   IPR015890
- InterPro:   IPR005802 [H]

Pfam domain/function: PF04715 Anth_synt_I_N; PF00425 Chorismate_bind [H]

EC number: =2.6.1.85 [H]

Molecular weight: Translated: 50036; Mature: 50036

Theoretical pI: Translated: 7.02; Mature: 7.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIDSTLITLDYHDFSSESYEKFSRLPGFVLLQSTDKSTGRYDILSAYPYERMVIENNVHD
CCCCEEEEEEECCCCCHHHHHHHCCCCEEEEECCCCCCCCEEEEECCCCCEEEEECCCCC
KDLVLTELKNKLKIEESEFDLPFQGGAIGYVSYDFGSLLHNHEQYSQKDLAHIPVLNFGF
HHHHHHHHHHHHEECCCCCCCCCCCCEEEEEEECHHHHHHHHHHHHHCCCCCCCEEECCC
YDWAIIVDHHLKKATLFARNSHSSTKSVVDKIKNILNDQPMKSVQFSVQAEFLPLISKEN
HHEEEEEHHHHHHHHEEECCCCCHHHHHHHHHHHHHCCCCCHHHEEEEEEHHHHHHCCCH
YRSSFNAIQQALRAGRSYQVNFTQPFQTKFTGDLWDMYQRVNKNNPVPYAAFIRTEEADI
HHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCHHHHHHHHHCCCCCCCEEEEEECCCCCE
LSFSPERFLLYDNGEMLTSPIKGTIHRSKDPVVDKKLKEQLLKCPKNKAENVMIVDLLRN
EEECCCEEEEEECCCEEECCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCEEEHHHHHH
DLGKLAKAGSVKVMNLCHIQSFNAVHHLVSDIRALCKEDIHPIEAFFSCFPGGSITGAPK
HHHHHHCCCCEEEEEEEHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCCC
LETMKIISEQETYKRGVYCGCIAYFSQHGRFDANIAIRTVTAKDNVLYLAAGGGIVIDSD
HHHHHHHHHHHHHHCCCHHHHHHHHHHCCCEECEEEEEEEEECCCEEEEEECCCEEECCC
WEDEYRECFTKITAIINGIK
CCHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MIDSTLITLDYHDFSSESYEKFSRLPGFVLLQSTDKSTGRYDILSAYPYERMVIENNVHD
CCCCEEEEEEECCCCCHHHHHHHCCCCEEEEECCCCCCCCEEEEECCCCCEEEEECCCCC
KDLVLTELKNKLKIEESEFDLPFQGGAIGYVSYDFGSLLHNHEQYSQKDLAHIPVLNFGF
HHHHHHHHHHHHEECCCCCCCCCCCCEEEEEEECHHHHHHHHHHHHHCCCCCCCEEECCC
YDWAIIVDHHLKKATLFARNSHSSTKSVVDKIKNILNDQPMKSVQFSVQAEFLPLISKEN
HHEEEEEHHHHHHHHEEECCCCCHHHHHHHHHHHHHCCCCCHHHEEEEEEHHHHHHCCCH
YRSSFNAIQQALRAGRSYQVNFTQPFQTKFTGDLWDMYQRVNKNNPVPYAAFIRTEEADI
HHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCHHHHHHHHHCCCCCCCEEEEEECCCCCE
LSFSPERFLLYDNGEMLTSPIKGTIHRSKDPVVDKKLKEQLLKCPKNKAENVMIVDLLRN
EEECCCEEEEEECCCEEECCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCEEEHHHHHH
DLGKLAKAGSVKVMNLCHIQSFNAVHHLVSDIRALCKEDIHPIEAFFSCFPGGSITGAPK
HHHHHHCCCCEEEEEEEHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCCC
LETMKIISEQETYKRGVYCGCIAYFSQHGRFDANIAIRTVTAKDNVLYLAAGGGIVIDSD
HHHHHHHHHHHHHHCCCHHHHHHHHHHCCCEECEEEEEEEEECCCEEEEEECCCEEECCC
WEDEYRECFTKITAIINGIK
CCHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 6330050; 9097040; 9278503; 7896119; 2251281; 7592344 [H]