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The map label for this gene is coaE

Identifier: 52841697

GI number: 52841697

Start: 1619956

End: 1620579

Strand: Reverse

Name: coaE

Synonym: lpg1467

Alternate gene names: 52841697

Gene position: 1620579-1619956 (Counterclockwise)

Preceding gene: 52841698

Following gene: 52841696

Centisome position: 47.7

GC content: 36.06

Gene sequence:

>624_bases
ATGAAGGAGCCCACTCAGATGGTTTATTCAGTGGGACTAACTGGTAATATTGCCAGTGGCAAAAGTACAGTCGCAGAATT
TTTTTCCGAACTGGGTATAAATGTTATTTATGCAGATAAAATTGCCAAAGAATTAACTTCTAAAAATACACCCTGCTACC
AGGATATTATTTCACATTTTGGTTCTTCAGTGGTTCTTAATAATGGTGAGCTTGATCGGAAGCGTATAAGAGATATTATA
TTTTCCAATTCAAATGAGCGCTTATGGCTTGAAAGTCTATTACATCCAGTCATCCGTAAAAAAATTGAAGAGCAACTCAT
CGTCTGCACTTCGCCATATTGCCTTATTGAAATTCCTTTGCTGTTTAATAAACATCACTACCCCTATCTTCAAAAAGTTC
TATTGGTTATTGCTCCCCTAGAATCTCAGCTAGACAGAATTGTTAAAAGAGATCATTGCACAAAAAAGCAAGCATTAGCT
ATTTTAGCCACACAACCTAATTTAGAGCAACGCTTGGAAGCAGCGGATGATGTGCTGATCAATGAATCTGGATTGAGTGA
ATTAAAAGCTAAGGTGAATAAGCTTCATCAAAAATATCTTAGGGAAGCAAAAATCAAACAGTAA

Upstream 100 bases:

>100_bases
AATCGGGATGATGCAGCCTTAGCTGCCCAGGCCTATTGTAAAGAAAACAGTACACTACCTGCTACTTGTTATATTAATAT
GGTAACTTGCGCAAACAAAA

Downstream 100 bases:

>100_bases
CAATAAATTTCTAGCAAAAGACCAGTTAATATATGGATTTTAAAGATTTTTTTATTTTCAACAACTTTTATGTTAGTCTT
AACACAAAATTCACCTTAAT

Product: dephospho-CoA kinase

Products: NA

Alternate protein names: Dephosphocoenzyme A kinase [H]

Number of amino acids: Translated: 207; Mature: 207

Protein sequence:

>207_residues
MKEPTQMVYSVGLTGNIASGKSTVAEFFSELGINVIYADKIAKELTSKNTPCYQDIISHFGSSVVLNNGELDRKRIRDII
FSNSNERLWLESLLHPVIRKKIEEQLIVCTSPYCLIEIPLLFNKHHYPYLQKVLLVIAPLESQLDRIVKRDHCTKKQALA
ILATQPNLEQRLEAADDVLINESGLSELKAKVNKLHQKYLREAKIKQ

Sequences:

>Translated_207_residues
MKEPTQMVYSVGLTGNIASGKSTVAEFFSELGINVIYADKIAKELTSKNTPCYQDIISHFGSSVVLNNGELDRKRIRDII
FSNSNERLWLESLLHPVIRKKIEEQLIVCTSPYCLIEIPLLFNKHHYPYLQKVLLVIAPLESQLDRIVKRDHCTKKQALA
ILATQPNLEQRLEAADDVLINESGLSELKAKVNKLHQKYLREAKIKQ
>Mature_207_residues
MKEPTQMVYSVGLTGNIASGKSTVAEFFSELGINVIYADKIAKELTSKNTPCYQDIISHFGSSVVLNNGELDRKRIRDII
FSNSNERLWLESLLHPVIRKKIEEQLIVCTSPYCLIEIPLLFNKHHYPYLQKVLLVIAPLESQLDRIVKRDHCTKKQALA
ILATQPNLEQRLEAADDVLINESGLSELKAKVNKLHQKYLREAKIKQ

Specific function: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A [H]

COG id: COG0237

COG function: function code H; Dephospho-CoA kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 DPCK (dephospho-CoA kinase) domain [H]

Homologues:

Organism=Homo sapiens, GI191252797, Length=193, Percent_Identity=34.1968911917098, Blast_Score=112, Evalue=3e-25,
Organism=Homo sapiens, GI191252795, Length=193, Percent_Identity=34.1968911917098, Blast_Score=112, Evalue=3e-25,
Organism=Homo sapiens, GI110227607, Length=204, Percent_Identity=25.4901960784314, Blast_Score=79, Evalue=3e-15,
Organism=Homo sapiens, GI110227605, Length=204, Percent_Identity=25.4901960784314, Blast_Score=77, Evalue=9e-15,
Organism=Homo sapiens, GI110227603, Length=204, Percent_Identity=25.4901960784314, Blast_Score=77, Evalue=9e-15,
Organism=Homo sapiens, GI110227601, Length=204, Percent_Identity=25.4901960784314, Blast_Score=77, Evalue=9e-15,
Organism=Homo sapiens, GI205277394, Length=204, Percent_Identity=25.4901960784314, Blast_Score=77, Evalue=1e-14,
Organism=Escherichia coli, GI1786292, Length=197, Percent_Identity=42.1319796954315, Blast_Score=158, Evalue=3e-40,
Organism=Caenorhabditis elegans, GI17554944, Length=194, Percent_Identity=29.8969072164948, Blast_Score=104, Evalue=4e-23,
Organism=Caenorhabditis elegans, GI25143409, Length=198, Percent_Identity=27.2727272727273, Blast_Score=69, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6320402, Length=196, Percent_Identity=28.0612244897959, Blast_Score=77, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24644728, Length=201, Percent_Identity=29.8507462686567, Blast_Score=102, Evalue=2e-22,
Organism=Drosophila melanogaster, GI24658602, Length=167, Percent_Identity=28.7425149700599, Blast_Score=83, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001977 [H]

Pfam domain/function: PF01121 CoaE [H]

EC number: =2.7.1.24 [H]

Molecular weight: Translated: 23583; Mature: 23583

Theoretical pI: Translated: 8.86; Mature: 8.86

Prosite motif: PS01294 COAE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKEPTQMVYSVGLTGNIASGKSTVAEFFSELGINVIYADKIAKELTSKNTPCYQDIISHF
CCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCEEEEHHHHHHHHHCCCCCHHHHHHHHC
GSSVVLNNGELDRKRIRDIIFSNSNERLWLESLLHPVIRKKIEEQLIVCTSPYCLIEIPL
CCEEEEECCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHEEEECCCCEEEEEHH
LFNKHHYPYLQKVLLVIAPLESQLDRIVKRDHCTKKQALAILATQPNLEQRLEAADDVLI
HHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHEEEECCCCHHHHHHHHHHHHC
NESGLSELKAKVNKLHQKYLREAKIKQ
CCCCHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MKEPTQMVYSVGLTGNIASGKSTVAEFFSELGINVIYADKIAKELTSKNTPCYQDIISHF
CCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCEEEEHHHHHHHHHCCCCCHHHHHHHHC
GSSVVLNNGELDRKRIRDIIFSNSNERLWLESLLHPVIRKKIEEQLIVCTSPYCLIEIPL
CCEEEEECCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHEEEECCCCEEEEEHH
LFNKHHYPYLQKVLLVIAPLESQLDRIVKRDHCTKKQALAILATQPNLEQRLEAADDVLI
HHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHEEEECCCCHHHHHHHHHHHHC
NESGLSELKAKVNKLHQKYLREAKIKQ
CCCCHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA