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The map label for this gene is yybO [H]

Identifier: 52841634

GI number: 52841634

Start: 1548437

End: 1549729

Strand: Direct

Name: yybO [H]

Synonym: lpg1404

Alternate gene names: 52841634

Gene position: 1548437-1549729 (Clockwise)

Preceding gene: 52841633

Following gene: 52841636

Centisome position: 45.57

GC content: 40.76

Gene sequence:

>1293_bases
TTGACCGCACATTACAACGTCGCTTCAAACAGTGGAGCAAGAAATACACTTGCAACGTCTTATTTTATTTTTTTTCTAGC
CGCTTCATTTTACTTGTATGAATTCATACTACAAGTAGCACCAAGCGTTATGGCAGAGTCGATGATGAAAACCTTTGGGG
TGACGGGTCAAGGCTTTGGTGTCATTTCAGCTTTTTATTTTTATGCTTATGCCCCTACACAATTGCCAGCAGGAGTATTA
TACGATAGATATGGACCACGCAAGTTAATGACTTTTGCAATCGTTTTGTGTGCATTTGGTTCTGCCTTTTTTGCTTCCAC
TGACAGTGTATTTACAGCTTGCATAGGCCGATTTTTGATCGGAATAGGCTCTGCGTTTTCTTTTATCGGTGTTTTGGTCC
TTATTTCACGCTGGTTTCCCCCTTATTATTTTGCAATTCTAGCAGGGGTAGCGCAGTTGATGAGTTCAGTCGGCGCTATG
TTTGGTGAAATGCCGTTGGCAGCTTTAATTGATCTGGTTGGATGGAGAAGTGCGAGTTTTATTTTAGCGGGTGTTGGATT
TCTCTTGGCTATTTTATTTTGGGTATTTATTCGAGATTATCCTCATCAGCAAAATCAGACAATCCCTGATCATTATTTAA
GAGATGAATGGAAGCGCTTAGTTGCTGTCTGTAAACATGCTTATACATGGATTATCGGTGGTTATGCTTTTGCAATTTGG
ACTCCTATTGCAGTATTTGCTGCACTTTGGGGGGTTCCTTTTTTACAGGAAAAATTTCAAGTAAGCGTAGTGGCTGCATC
AGGCTTATGCAGTATGATTTGGCTAGGCATTGGTGTTGGTAGTCCCTTATTAGGTTGGTTGAGTGATAAATTGGAGAGTC
GCCGTATTGCATTGATTATCAGTGCGGTTTTAGGACTGATTGCAACTCTGATTATCCTTTATTGGTCTGAGTTATCTTAT
AATTGGGCTTATTTTGTCTTGTTCGTTTTAGGATTAGGTGCTGGAGGACAGACGGTAAGTTTTGCAGTAGTTAAAGAAAA
TAATACACCGGAATTAGTTGGCACAGCATCTGGTTTTAATAATTTGTCTGTATTAATTGGTGGGGCCATTTTCCAGCCCC
TCGTTGGTTATATCTTGCAACAGACGGGATCATGGCGAATTGTCAATGGTGCTCATGTATACAGTATATCGAGTTATCAG
ACTGCGTTGCTTGTTATGCCAGTATGCTTCCTGGCCAGTTTGCTTATTGCCACTTTTTTGCTTAAGGAATCGCATCCTGC
GCGCAGAGATTAA

Upstream 100 bases:

>100_bases
ATTGCAATTTTAGGTGCAGTGTATCCTATAATAAAATCATATTGACAAACTAAAGAATCATAAGGTTTAATTTCATAAAA
ATTAACAGAGTGATTTTAAA

Downstream 100 bases:

>100_bases
TAACAGATTTATCAATTCAATTTTGCGTTATTGACCAAAAACAAAGGAATCAGATTATGTAAATGTGGCCTGTTCTTATG
AGTTAGCCACATTACTATTT

Product: major facilitator family transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 430; Mature: 429

Protein sequence:

>430_residues
MTAHYNVASNSGARNTLATSYFIFFLAASFYLYEFILQVAPSVMAESMMKTFGVTGQGFGVISAFYFYAYAPTQLPAGVL
YDRYGPRKLMTFAIVLCAFGSAFFASTDSVFTACIGRFLIGIGSAFSFIGVLVLISRWFPPYYFAILAGVAQLMSSVGAM
FGEMPLAALIDLVGWRSASFILAGVGFLLAILFWVFIRDYPHQQNQTIPDHYLRDEWKRLVAVCKHAYTWIIGGYAFAIW
TPIAVFAALWGVPFLQEKFQVSVVAASGLCSMIWLGIGVGSPLLGWLSDKLESRRIALIISAVLGLIATLIILYWSELSY
NWAYFVLFVLGLGAGGQTVSFAVVKENNTPELVGTASGFNNLSVLIGGAIFQPLVGYILQQTGSWRIVNGAHVYSISSYQ
TALLVMPVCFLASLLIATFLLKESHPARRD

Sequences:

>Translated_430_residues
MTAHYNVASNSGARNTLATSYFIFFLAASFYLYEFILQVAPSVMAESMMKTFGVTGQGFGVISAFYFYAYAPTQLPAGVL
YDRYGPRKLMTFAIVLCAFGSAFFASTDSVFTACIGRFLIGIGSAFSFIGVLVLISRWFPPYYFAILAGVAQLMSSVGAM
FGEMPLAALIDLVGWRSASFILAGVGFLLAILFWVFIRDYPHQQNQTIPDHYLRDEWKRLVAVCKHAYTWIIGGYAFAIW
TPIAVFAALWGVPFLQEKFQVSVVAASGLCSMIWLGIGVGSPLLGWLSDKLESRRIALIISAVLGLIATLIILYWSELSY
NWAYFVLFVLGLGAGGQTVSFAVVKENNTPELVGTASGFNNLSVLIGGAIFQPLVGYILQQTGSWRIVNGAHVYSISSYQ
TALLVMPVCFLASLLIATFLLKESHPARRD
>Mature_429_residues
TAHYNVASNSGARNTLATSYFIFFLAASFYLYEFILQVAPSVMAESMMKTFGVTGQGFGVISAFYFYAYAPTQLPAGVLY
DRYGPRKLMTFAIVLCAFGSAFFASTDSVFTACIGRFLIGIGSAFSFIGVLVLISRWFPPYYFAILAGVAQLMSSVGAMF
GEMPLAALIDLVGWRSASFILAGVGFLLAILFWVFIRDYPHQQNQTIPDHYLRDEWKRLVAVCKHAYTWIIGGYAFAIWT
PIAVFAALWGVPFLQEKFQVSVVAASGLCSMIWLGIGVGSPLLGWLSDKLESRRIALIISAVLGLIATLIILYWSELSYN
WAYFVLFVLGLGAGGQTVSFAVVKENNTPELVGTASGFNNLSVLIGGAIFQPLVGYILQQTGSWRIVNGAHVYSISSYQT
ALLVMPVCFLASLLIATFLLKESHPARRD

Specific function: Uptake Of D-Glucarate. [C]

COG id: COG0477

COG function: function code GEPR; Permeases of the major facilitator superfamily

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Phthalate permease family [H]

Homologues:

Organism=Escherichia coli, GI1789152, Length=402, Percent_Identity=23.6318407960199, Blast_Score=74, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17561500, Length=274, Percent_Identity=24.4525547445255, Blast_Score=66, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI115534562, Length=274, Percent_Identity=24.4525547445255, Blast_Score=66, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 47088; Mature: 46957

Theoretical pI: Translated: 8.61; Mature: 8.61

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHCCCCCCCC
>Mature Secondary Structure 
TAHYNVASNSGARNTLATSYFIFFLAASFYLYEFILQVAPSVMAESMMKTFGVTGQGFG
CCEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHH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HHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377 [H]