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The map label for this gene is ycfH [H]

Identifier: 52841632

GI number: 52841632

Start: 1546357

End: 1547169

Strand: Direct

Name: ycfH [H]

Synonym: lpg1402

Alternate gene names: 52841632

Gene position: 1546357-1547169 (Clockwise)

Preceding gene: 52841631

Following gene: 52841633

Centisome position: 45.51

GC content: 38.99

Gene sequence:

>813_bases
TTGATATTATTTTGGGGTATAAAGGTGCTGGTCGACTCTCATTGTCATTTAAATTTTATCGATTTGACTCATTTTAATCA
TGATCTTGCTCAGGTAATCAATCAGGCTCGCGAGAATGGGGTGGAGTATTTCTTGTCTGTTTGTGTTGAGTTGAGCGATT
ATCCTCAATTAGAGCGTTTAGCTAAGGATTATCCTGATATTAGCATTTCTGTTGGAGTGCATCCGAATAGTGAAATGAAT
TATCCTGTTACGGCACAGATGTTATGTGAATTGGCTCAAAATCCTGCCTGTATTGCCATAGGAGAAACAGGGCTTGATTA
TTATCGTAATCCCACTGAGGAAGCTCAATCTTTGCAACGAGATCGCTTCAGGGAACATATCAAGGCGGCACTTATAACTT
CCAAGCCGTTAATTATTCATACCAGGCAAGCTGCTGAAGATACTTTGTTGATGATGGCTAAGGAGGGGGCTAGTCAGATA
GGCGGAGTCATGCACTGTTTTGCTGAAGACTTTGATATTGCGCAAAGAGCAATTGATTTAAATTTTTATATATCATTTTC
CGGGATAGTTACTTTTAAAAATGCTGTTTCATTGCAAGATGTAGCCAGACAGATACCTTTAGAGAGGATATTGATAGAGA
CAGATTCACCTTATTTGGCTCCGGTTCCACACAGAGGAAAGCAAAATCATCCCGCTTTGGTGAAACACGTTGCAGAAACT
ATCGCACAACTCAGAGGGATGGATTTCCAAGAGATAGCAGAAATCACTACAAACAATTTTTATAATTGTTTTAATATCAA
ACGACAAGGATAA

Upstream 100 bases:

>100_bases
CTATGTAACAAGATAGAAACTTATTTGGCAGGAATGCTAAAATCATGTCAGGTTACAGATACTATATAGAGTTTTCATTT
ATTCATGAACAATATATTCA

Downstream 100 bases:

>100_bases
ATCATTGGTAAATCGTAGTTCTCAACTTCAAAGCAGAAGCAGTAATTTTTTTGCCTGTGAATAAAGGTTTTAGTAGTATT
GATATATCCTATTGCAAATT

Product: deoxyribonuclease TatD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 270; Mature: 270

Protein sequence:

>270_residues
MILFWGIKVLVDSHCHLNFIDLTHFNHDLAQVINQARENGVEYFLSVCVELSDYPQLERLAKDYPDISISVGVHPNSEMN
YPVTAQMLCELAQNPACIAIGETGLDYYRNPTEEAQSLQRDRFREHIKAALITSKPLIIHTRQAAEDTLLMMAKEGASQI
GGVMHCFAEDFDIAQRAIDLNFYISFSGIVTFKNAVSLQDVARQIPLERILIETDSPYLAPVPHRGKQNHPALVKHVAET
IAQLRGMDFQEIAEITTNNFYNCFNIKRQG

Sequences:

>Translated_270_residues
MILFWGIKVLVDSHCHLNFIDLTHFNHDLAQVINQARENGVEYFLSVCVELSDYPQLERLAKDYPDISISVGVHPNSEMN
YPVTAQMLCELAQNPACIAIGETGLDYYRNPTEEAQSLQRDRFREHIKAALITSKPLIIHTRQAAEDTLLMMAKEGASQI
GGVMHCFAEDFDIAQRAIDLNFYISFSGIVTFKNAVSLQDVARQIPLERILIETDSPYLAPVPHRGKQNHPALVKHVAET
IAQLRGMDFQEIAEITTNNFYNCFNIKRQG
>Mature_270_residues
MILFWGIKVLVDSHCHLNFIDLTHFNHDLAQVINQARENGVEYFLSVCVELSDYPQLERLAKDYPDISISVGVHPNSEMN
YPVTAQMLCELAQNPACIAIGETGLDYYRNPTEEAQSLQRDRFREHIKAALITSKPLIIHTRQAAEDTLLMMAKEGASQI
GGVMHCFAEDFDIAQRAIDLNFYISFSGIVTFKNAVSLQDVARQIPLERILIETDSPYLAPVPHRGKQNHPALVKHVAET
IAQLRGMDFQEIAEITTNNFYNCFNIKRQG

Specific function: Unknown

COG id: COG0084

COG function: function code L; Mg-dependent DNase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tatD DNase family [H]

Homologues:

Organism=Homo sapiens, GI226061853, Length=272, Percent_Identity=29.0441176470588, Blast_Score=95, Evalue=8e-20,
Organism=Homo sapiens, GI225903424, Length=251, Percent_Identity=29.0836653386454, Blast_Score=94, Evalue=1e-19,
Organism=Homo sapiens, GI110349734, Length=267, Percent_Identity=28.4644194756554, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI110349730, Length=267, Percent_Identity=28.4644194756554, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI226061614, Length=258, Percent_Identity=27.1317829457364, Blast_Score=88, Evalue=1e-17,
Organism=Homo sapiens, GI14042943, Length=269, Percent_Identity=28.6245353159851, Blast_Score=86, Evalue=2e-17,
Organism=Homo sapiens, GI225903439, Length=227, Percent_Identity=28.1938325991189, Blast_Score=75, Evalue=7e-14,
Organism=Homo sapiens, GI226061595, Length=229, Percent_Identity=28.3842794759825, Blast_Score=73, Evalue=3e-13,
Organism=Escherichia coli, GI1787342, Length=257, Percent_Identity=46.3035019455253, Blast_Score=240, Evalue=6e-65,
Organism=Escherichia coli, GI48994985, Length=253, Percent_Identity=30.4347826086957, Blast_Score=115, Evalue=4e-27,
Organism=Escherichia coli, GI87082439, Length=261, Percent_Identity=29.8850574712644, Blast_Score=112, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI17559024, Length=271, Percent_Identity=28.0442804428044, Blast_Score=124, Evalue=7e-29,
Organism=Caenorhabditis elegans, GI71980746, Length=266, Percent_Identity=26.3157894736842, Blast_Score=87, Evalue=8e-18,
Organism=Caenorhabditis elegans, GI17543026, Length=289, Percent_Identity=25.6055363321799, Blast_Score=84, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17565396, Length=294, Percent_Identity=24.4897959183673, Blast_Score=72, Evalue=4e-13,
Organism=Drosophila melanogaster, GI24648690, Length=294, Percent_Identity=28.2312925170068, Blast_Score=93, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24586117, Length=216, Percent_Identity=30.0925925925926, Blast_Score=75, Evalue=4e-14,
Organism=Drosophila melanogaster, GI221330018, Length=216, Percent_Identity=30.0925925925926, Blast_Score=75, Evalue=5e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015992
- InterPro:   IPR001130
- InterPro:   IPR018228
- InterPro:   IPR012278
- InterPro:   IPR015991 [H]

Pfam domain/function: PF01026 TatD_DNase [H]

EC number: 3.1.21.- [C]

Molecular weight: Translated: 30547; Mature: 30547

Theoretical pI: Translated: 5.51; Mature: 5.51

Prosite motif: PS01137 TATD_1 ; PS01090 TATD_2 ; PS01091 TATD_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MILFWGIKVLVDSHCHLNFIDLTHFNHDLAQVINQARENGVEYFLSVCVELSDYPQLERL
CEEEEEEEHHHCCCCCEEEEEHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
AKDYPDISISVGVHPNSEMNYPVTAQMLCELAQNPACIAIGETGLDYYRNPTEEAQSLQR
HHHCCCCEEEEECCCCCCCCCCHHHHHHHHHHCCCCEEEECCCCCHHHCCCHHHHHHHHH
DRFREHIKAALITSKPLIIHTRQAAEDTLLMMAKEGASQIGGVMHCFAEDFDIAQRAIDL
HHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHEEE
NFYISFSGIVTFKNAVSLQDVARQIPLERILIETDSPYLAPVPHRGKQNHPALVKHVAET
EEEEEEECEEEEHHHHHHHHHHHHCCHHHEEEECCCCEECCCCCCCCCCCHHHHHHHHHH
IAQLRGMDFQEIAEITTNNFYNCFNIKRQG
HHHHHCCCHHHHHHHHHCCCEEEEEEEECC
>Mature Secondary Structure
MILFWGIKVLVDSHCHLNFIDLTHFNHDLAQVINQARENGVEYFLSVCVELSDYPQLERL
CEEEEEEEHHHCCCCCEEEEEHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
AKDYPDISISVGVHPNSEMNYPVTAQMLCELAQNPACIAIGETGLDYYRNPTEEAQSLQR
HHHCCCCEEEEECCCCCCCCCCHHHHHHHHHHCCCCEEEECCCCCHHHCCCHHHHHHHHH
DRFREHIKAALITSKPLIIHTRQAAEDTLLMMAKEGASQIGGVMHCFAEDFDIAQRAIDL
HHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHEEE
NFYISFSGIVTFKNAVSLQDVARQIPLERILIETDSPYLAPVPHRGKQNHPALVKHVAET
EEEEEEECEEEEHHHHHHHHHHHHCCHHHEEEECCCCEECCCCCCCCCCCHHHHHHHHHH
IAQLRGMDFQEIAEITTNNFYNCFNIKRQG
HHHHHCCCHHHHHHHHHCCCEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]