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The map label for this gene is fabH

Identifier: 52841623

GI number: 52841623

Start: 1539042

End: 1539995

Strand: Direct

Name: fabH

Synonym: lpg1393

Alternate gene names: 52841623

Gene position: 1539042-1539995 (Clockwise)

Preceding gene: 52841622

Following gene: 52841624

Centisome position: 45.3

GC content: 39.41

Gene sequence:

>954_bases
ATGAAAAATGCTGTTATTAATGGCACTGGAAGTTACTCTCCAGAGAGACAAATGACTAATGCTGAACTGGAAACCATGCT
TGATACTAGCGATGAATGGATTGTTACCAGGACTGGTATTAGTAGCCGTAGTGTTGCTCAAGAACATGAAACAACATCTT
ATATGGCTTCCAGAGCAGCAGAGCAAGCACTAGAGGCATCAGGCCTTGATGCTGAAGAAATTGATTTGATATTAGTAGCA
ACATGTACCCCAGATTATTTTTTTCCTAGCGTTGCCTGTCACGTACAACATGCTTTAGGAATCAAAAGACCTATTCCGGC
TTTTGACATTGGAGCTGCATGCAGCGGTTTTGTTTATGCGATGGATGTAGCGAAACAATACATTGCTACAGGGGCTGCCA
AACACGTTCTTGTCGTAGGCAGCGAGAGCATGTCAAGAGCGGTAGATTGGACTGATCGTTCTATTTGTGTCTTATTCGGA
GATGGCGCAGGCGCTGTTGTTTTAAGCGCAAGTGATCGCCAAGGGATTATGGGTAGTGTTTTACATTCTGCCTATGACTC
TGATAAATTACTAGTCCTTCGTAATTCAACTTTTGAACAAGATCGTGCAACGATTGGAATGCGAGGTAATGAGGTATTCA
AAATTGCTGTTAATATTATGGGTAATATTGTTGATGAAGTATTAGAAGCAAGTCATTTAAAAAAATCTGATATTGATTGG
CTGATACCTCATCAAGCCAATATACGCATCATACAAGCCATAGCTAAAAAATTATCTCTTCCTATGTCACATGTTATTGT
TACAATTGGTAACCAAGGTAACACATCGGCTGCTTCTATTCCCTTAGCACTTGATTATTCTATTAAAAATAATCAGATTA
AAAGGGATGAAATATTATTAATTGAATCCTTTGGTGGTGGAATGACCTGGGGCGCTATGGTTATTCGTTACTAA

Upstream 100 bases:

>100_bases
TTCAACATGCTATTGAACAGGCTGTTCTTGAAGTAAAAAATAATGTTGTCGATTTAGTGCGTGATCAAATAAATGATTTT
ATAAATCAAGGATTGTTGTT

Downstream 100 bases:

>100_bases
ATTAACTAATAAGGATTAATTCTATTATGGTAAAATCAGCATTTGTATTTCCTGGACAGGGATCGCAGTCTATCGGCATG
TTGTCTGACTTTATGCCACA

Product: 3-oxoacyl-(acyl carrier protein) synthase II FabH

Products: NA

Alternate protein names: 3-oxoacyl-[acyl-carrier-protein] synthase III; Beta-ketoacyl-ACP synthase III; KAS III [H]

Number of amino acids: Translated: 317; Mature: 317

Protein sequence:

>317_residues
MKNAVINGTGSYSPERQMTNAELETMLDTSDEWIVTRTGISSRSVAQEHETTSYMASRAAEQALEASGLDAEEIDLILVA
TCTPDYFFPSVACHVQHALGIKRPIPAFDIGAACSGFVYAMDVAKQYIATGAAKHVLVVGSESMSRAVDWTDRSICVLFG
DGAGAVVLSASDRQGIMGSVLHSAYDSDKLLVLRNSTFEQDRATIGMRGNEVFKIAVNIMGNIVDEVLEASHLKKSDIDW
LIPHQANIRIIQAIAKKLSLPMSHVIVTIGNQGNTSAASIPLALDYSIKNNQIKRDEILLIESFGGGMTWGAMVIRY

Sequences:

>Translated_317_residues
MKNAVINGTGSYSPERQMTNAELETMLDTSDEWIVTRTGISSRSVAQEHETTSYMASRAAEQALEASGLDAEEIDLILVA
TCTPDYFFPSVACHVQHALGIKRPIPAFDIGAACSGFVYAMDVAKQYIATGAAKHVLVVGSESMSRAVDWTDRSICVLFG
DGAGAVVLSASDRQGIMGSVLHSAYDSDKLLVLRNSTFEQDRATIGMRGNEVFKIAVNIMGNIVDEVLEASHLKKSDIDW
LIPHQANIRIIQAIAKKLSLPMSHVIVTIGNQGNTSAASIPLALDYSIKNNQIKRDEILLIESFGGGMTWGAMVIRY
>Mature_317_residues
MKNAVINGTGSYSPERQMTNAELETMLDTSDEWIVTRTGISSRSVAQEHETTSYMASRAAEQALEASGLDAEEIDLILVA
TCTPDYFFPSVACHVQHALGIKRPIPAFDIGAACSGFVYAMDVAKQYIATGAAKHVLVVGSESMSRAVDWTDRSICVLFG
DGAGAVVLSASDRQGIMGSVLHSAYDSDKLLVLRNSTFEQDRATIGMRGNEVFKIAVNIMGNIVDEVLEASHLKKSDIDW
LIPHQANIRIIQAIAKKLSLPMSHVIVTIGNQGNTSAASIPLALDYSIKNNQIKRDEILLIESFGGGMTWGAMVIRY

Specific function: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the

COG id: COG0332

COG function: function code I; 3-oxoacyl-[acyl-carrier-protein] synthase III

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabH family [H]

Homologues:

Organism=Escherichia coli, GI1787333, Length=314, Percent_Identity=51.2738853503185, Blast_Score=332, Evalue=3e-92,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013751
- InterPro:   IPR013747
- InterPro:   IPR004655
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF08545 ACP_syn_III; PF08541 ACP_syn_III_C [H]

EC number: =2.3.1.180 [H]

Molecular weight: Translated: 34300; Mature: 34300

Theoretical pI: Translated: 5.16; Mature: 5.16

Prosite motif: PS00687 ALDEHYDE_DEHYDR_GLU

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNAVINGTGSYSPERQMTNAELETMLDTSDEWIVTRTGISSRSVAQEHETTSYMASRAA
CCCCEECCCCCCCCCHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHH
EQALEASGLDAEEIDLILVATCTPDYFFPSVACHVQHALGIKRPIPAFDIGAACSGFVYA
HHHHHHCCCCHHHEEEEEEEECCCCHHCHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHH
MDVAKQYIATGAAKHVLVVGSESMSRAVDWTDRSICVLFGDGAGAVVLSASDRQGIMGSV
HHHHHHHHHCCCCCEEEEECCCHHHHHCCCCCCEEEEEEECCCCEEEEECCCCCCHHHHH
LHSAYDSDKLLVLRNSTFEQDRATIGMRGNEVFKIAVNIMGNIVDEVLEASHLKKSDIDW
HHHHCCCCCEEEEECCCCCCCCCEEECCCCEEEEEHHHHHHHHHHHHHHHHCCCCCCCCE
LIPHQANIRIIQAIAKKLSLPMSHVIVTIGNQGNTSAASIPLALDYSIKNNQIKRDEILL
ECCCCCCHHHHHHHHHHHCCCCEEEEEEECCCCCCCCEEEEEEEEEEECCCCCCCCEEEE
IESFGGGMTWGAMVIRY
EECCCCCCEEEEEEEEC
>Mature Secondary Structure
MKNAVINGTGSYSPERQMTNAELETMLDTSDEWIVTRTGISSRSVAQEHETTSYMASRAA
CCCCEECCCCCCCCCHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHH
EQALEASGLDAEEIDLILVATCTPDYFFPSVACHVQHALGIKRPIPAFDIGAACSGFVYA
HHHHHHCCCCHHHEEEEEEEECCCCHHCHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHH
MDVAKQYIATGAAKHVLVVGSESMSRAVDWTDRSICVLFGDGAGAVVLSASDRQGIMGSV
HHHHHHHHHCCCCCEEEEECCCHHHHHCCCCCCEEEEEEECCCCEEEEECCCCCCHHHHH
LHSAYDSDKLLVLRNSTFEQDRATIGMRGNEVFKIAVNIMGNIVDEVLEASHLKKSDIDW
HHHHCCCCCEEEEECCCCCCCCCEEECCCCEEEEEHHHHHHHHHHHHHHHHCCCCCCCCE
LIPHQANIRIIQAIAKKLSLPMSHVIVTIGNQGNTSAASIPLALDYSIKNNQIKRDEILL
ECCCCCCHHHHHHHHHHHCCCCEEEEEEECCCCCCCCEEEEEEEEEEECCCCCCCCEEEE
IESFGGGMTWGAMVIRY
EECCCCCCEEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA