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The map label for this gene is dtpA [H]

Identifier: 52841608

GI number: 52841608

Start: 1524359

End: 1525801

Strand: Reverse

Name: dtpA [H]

Synonym: lpg1378

Alternate gene names: 52841608

Gene position: 1525801-1524359 (Counterclockwise)

Preceding gene: 52841615

Following gene: 52841607

Centisome position: 44.91

GC content: 36.66

Gene sequence:

>1443_bases
ATGGAAAAACACCCAAAATCTCTCCGCATCTACTTTACAACCGAAATGTGGGAACGTTATGGTTTTTACGCAGTTCAATC
CTTATTAGCACTTTATTTGGCCTTACACTTTAAATGGCCGGACAAAGAAATCTATTCTTTAGTAGGATCGTTCACAGCAC
TCACCTACCTCTCACCATTAGTAGGAGGCTGGATTGCTGATAAATTAATAGGCCAAAAACGCGCTATATTGCTGGGTGCT
ATTGTTCTGTTTTTAAGTTATTGCATGTTGTCATTGATTGATAATTCGCTGGCATTAACCTCTTCACTTGCAGGAGTAGC
TGTAGGAACAGGTTTATTAAAACCTAATATTTCTTCATTACTAGGTAATGAATATCCAGTAGGATCAACAAAAAGAGAAA
GTGGTTTTACTATTTTTTACATGGGCATCACGACAGGAATAATCCTCGGAACAACACTACCAAGCAAGTTTAATGAGTAT
TTTGGCTGGTCTGCTTCCTTCACCAGTGCATCAATCGGACTAATCATCGCATTTGTAGTGTTTTTATTTGGAATACATCA
GTACAAAATTAAGGATTATAATCCTTTTGTTTTACAACCAGGTAAAATCATTTCAGCTTTTGTGTTATTGGTTTTGCTGT
GGTCATTGTCATTTTATATTTTAAGTTCACCTCAGCTGGCGAATATCATGTTTGGACTTGTGGTTCTTTTTTCAGCCAGT
TACATTTTATATTCAGTAAATCGTGAAAGTGCAAATCAGTCCAGGCAAACATTAGTTATCGGGTTATTGTGCATCATCTC
TGTTATTTTCTGGGCATTTTATTTTCAGATGTTCATGTCCTTAACATTATTTATTGCGCGAGTAGTCGAGCCAAGCTTTT
TAGGTATCGATTTTCCCCCACCATACTACATCACAGTGCAAAGTATTGGTATGTTAATAATTGGTTATTTTCTTGCCAAA
AAGCACCGTAGTCTTACAATGATTGAAAGAGGCTTAAGTACCGGGAAAAAATTTGTACTTGCTATGGTATTCATGACACT
CGCCTACTCAATTATTGCCTTTGTAAGTACTGTAGTTGATAAATCCATTTTGATTTCACCTCTTCTTATCATCCCTGCCT
ACCTGATGATTTCTTTGGCTGAATTACTGCTTTCACCAGTAGGGTTGTCAGCAATAACTGTACTTGCTGACAAAAACAAG
GTAAGCACCATGATGGGTATCTTTTTCGTTTCATTAGGAATAGGAGGATTCCTTTCAGGAAAATTAGCCGATCTGACTGC
CATTCCTACTGGAGAGACAAATATAATCGTTTTAAAAACGCTCTACGCTACAGCATTCACCCAACAACTCAGTATATTAT
TCATTGCTACGTTAGGCTGCCTGGTATTGTTTGCTGTAATTAAATTTTTATTGACTCATATTCAGATATGCGAAAAACAA
TAA

Upstream 100 bases:

>100_bases
GAGAAAAACCAGATAAAATGACCAATCAATATTCATACTGTTTTTTATATGATATAATTTTTATTTAATAAATTAATTTA
ATCGTAGTTACTTAAATAAT

Downstream 100 bases:

>100_bases
TTAGATTTTTACGTTTTAGTTTTCCAGACTTGAAAACTAAAACCCTTTTTATACAAATCAATTGTTGATATTATTCAACC
CTTTTGACGGAATATATCTT

Product: proton/peptide symporter, POT family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 480; Mature: 480

Protein sequence:

>480_residues
MEKHPKSLRIYFTTEMWERYGFYAVQSLLALYLALHFKWPDKEIYSLVGSFTALTYLSPLVGGWIADKLIGQKRAILLGA
IVLFLSYCMLSLIDNSLALTSSLAGVAVGTGLLKPNISSLLGNEYPVGSTKRESGFTIFYMGITTGIILGTTLPSKFNEY
FGWSASFTSASIGLIIAFVVFLFGIHQYKIKDYNPFVLQPGKIISAFVLLVLLWSLSFYILSSPQLANIMFGLVVLFSAS
YILYSVNRESANQSRQTLVIGLLCIISVIFWAFYFQMFMSLTLFIARVVEPSFLGIDFPPPYYITVQSIGMLIIGYFLAK
KHRSLTMIERGLSTGKKFVLAMVFMTLAYSIIAFVSTVVDKSILISPLLIIPAYLMISLAELLLSPVGLSAITVLADKNK
VSTMMGIFFVSLGIGGFLSGKLADLTAIPTGETNIIVLKTLYATAFTQQLSILFIATLGCLVLFAVIKFLLTHIQICEKQ

Sequences:

>Translated_480_residues
MEKHPKSLRIYFTTEMWERYGFYAVQSLLALYLALHFKWPDKEIYSLVGSFTALTYLSPLVGGWIADKLIGQKRAILLGA
IVLFLSYCMLSLIDNSLALTSSLAGVAVGTGLLKPNISSLLGNEYPVGSTKRESGFTIFYMGITTGIILGTTLPSKFNEY
FGWSASFTSASIGLIIAFVVFLFGIHQYKIKDYNPFVLQPGKIISAFVLLVLLWSLSFYILSSPQLANIMFGLVVLFSAS
YILYSVNRESANQSRQTLVIGLLCIISVIFWAFYFQMFMSLTLFIARVVEPSFLGIDFPPPYYITVQSIGMLIIGYFLAK
KHRSLTMIERGLSTGKKFVLAMVFMTLAYSIIAFVSTVVDKSILISPLLIIPAYLMISLAELLLSPVGLSAITVLADKNK
VSTMMGIFFVSLGIGGFLSGKLADLTAIPTGETNIIVLKTLYATAFTQQLSILFIATLGCLVLFAVIKFLLTHIQICEKQ
>Mature_480_residues
MEKHPKSLRIYFTTEMWERYGFYAVQSLLALYLALHFKWPDKEIYSLVGSFTALTYLSPLVGGWIADKLIGQKRAILLGA
IVLFLSYCMLSLIDNSLALTSSLAGVAVGTGLLKPNISSLLGNEYPVGSTKRESGFTIFYMGITTGIILGTTLPSKFNEY
FGWSASFTSASIGLIIAFVVFLFGIHQYKIKDYNPFVLQPGKIISAFVLLVLLWSLSFYILSSPQLANIMFGLVVLFSAS
YILYSVNRESANQSRQTLVIGLLCIISVIFWAFYFQMFMSLTLFIARVVEPSFLGIDFPPPYYITVQSIGMLIIGYFLAK
KHRSLTMIERGLSTGKKFVLAMVFMTLAYSIIAFVSTVVDKSILISPLLIIPAYLMISLAELLLSPVGLSAITVLADKNK
VSTMMGIFFVSLGIGGFLSGKLADLTAIPTGETNIIVLKTLYATAFTQQLSILFIATLGCLVLFAVIKFLLTHIQICEKQ

Specific function: Proton-dependent permease that transports di- and tripeptides [H]

COG id: COG3104

COG function: function code E; Dipeptide/tripeptide permease

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PTR2/POT transporter (TC 2.A.17) family. DtpA subfamily [H]

Homologues:

Organism=Homo sapiens, GI4827008, Length=167, Percent_Identity=29.940119760479, Blast_Score=74, Evalue=3e-13,
Organism=Homo sapiens, GI226371746, Length=199, Percent_Identity=25.6281407035176, Blast_Score=69, Evalue=9e-12,
Organism=Escherichia coli, GI1787922, Length=457, Percent_Identity=28.0087527352298, Blast_Score=183, Evalue=2e-47,
Organism=Escherichia coli, GI1786927, Length=448, Percent_Identity=29.6875, Blast_Score=167, Evalue=1e-42,
Organism=Escherichia coli, GI1789911, Length=456, Percent_Identity=27.6315789473684, Blast_Score=167, Evalue=1e-42,
Organism=Escherichia coli, GI1790572, Length=474, Percent_Identity=25.9493670886076, Blast_Score=156, Evalue=3e-39,
Organism=Drosophila melanogaster, GI24639585, Length=204, Percent_Identity=27.9411764705882, Blast_Score=79, Evalue=7e-15,
Organism=Drosophila melanogaster, GI24639583, Length=204, Percent_Identity=27.9411764705882, Blast_Score=79, Evalue=7e-15,
Organism=Drosophila melanogaster, GI24639581, Length=204, Percent_Identity=27.9411764705882, Blast_Score=78, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR016196
- InterPro:   IPR000109
- InterPro:   IPR005279
- InterPro:   IPR018456 [H]

Pfam domain/function: PF00854 PTR2 [H]

EC number: NA

Molecular weight: Translated: 53011; Mature: 53011

Theoretical pI: Translated: 9.58; Mature: 9.58

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEKHPKSLRIYFTTEMWERYGFYAVQSLLALYLALHFKWPDKEIYSLVGSFTALTYLSPL
CCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHH
VGGWIADKLIGQKRAILLGAIVLFLSYCMLSLIDNSLALTSSLAGVAVGTGLLKPNISSL
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCHHHH
LGNEYPVGSTKRESGFTIFYMGITTGIILGTTLPSKFNEYFGWSASFTSASIGLIIAFVV
CCCCCCCCCCCCCCCCEEEEHHHHHHHHHCCCCCHHHHHHCCCCCCCCHHHHHHHHHHHH
FLFGIHQYKIKDYNPFVLQPGKIISAFVLLVLLWSLSFYILSSPQLANIMFGLVVLFSAS
HHHCCHHEEECCCCCCEECCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCH
YILYSVNRESANQSRQTLVIGLLCIISVIFWAFYFQMFMSLTLFIARVVEPSFLGIDFPP
HHEEECCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCCCC
PYYITVQSIGMLIIGYFLAKKHRSLTMIERGLSTGKKFVLAMVFMTLAYSIIAFVSTVVD
CCEEEHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KSILISPLLIIPAYLMISLAELLLSPVGLSAITVLADKNKVSTMMGIFFVSLGIGGFLSG
HHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHEEEEECCHHHHHHHHHHHHHHCCCHHCCC
KLADLTAIPTGETNIIVLKTLYATAFTQQLSILFIATLGCLVLFAVIKFLLTHIQICEKQ
CHHHEEECCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MEKHPKSLRIYFTTEMWERYGFYAVQSLLALYLALHFKWPDKEIYSLVGSFTALTYLSPL
CCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHH
VGGWIADKLIGQKRAILLGAIVLFLSYCMLSLIDNSLALTSSLAGVAVGTGLLKPNISSL
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCHHHH
LGNEYPVGSTKRESGFTIFYMGITTGIILGTTLPSKFNEYFGWSASFTSASIGLIIAFVV
CCCCCCCCCCCCCCCCEEEEHHHHHHHHHCCCCCHHHHHHCCCCCCCCHHHHHHHHHHHH
FLFGIHQYKIKDYNPFVLQPGKIISAFVLLVLLWSLSFYILSSPQLANIMFGLVVLFSAS
HHHCCHHEEECCCCCCEECCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCH
YILYSVNRESANQSRQTLVIGLLCIISVIFWAFYFQMFMSLTLFIARVVEPSFLGIDFPP
HHEEECCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCCCC
PYYITVQSIGMLIIGYFLAKKHRSLTMIERGLSTGKKFVLAMVFMTLAYSIIAFVSTVVD
CCEEEHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KSILISPLLIIPAYLMISLAELLLSPVGLSAITVLADKNKVSTMMGIFFVSLGIGGFLSG
HHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHEEEEECCHHHHHHHHHHHHHHCCCHHCCC
KLADLTAIPTGETNIIVLKTLYATAFTQQLSILFIATLGCLVLFAVIKFLLTHIQICEKQ
CHHHEEECCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA