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The map label for this gene is cutE

Identifier: 52841579

GI number: 52841579

Start: 1488183

End: 1489718

Strand: Reverse

Name: cutE

Synonym: lpg1349

Alternate gene names: 52841579

Gene position: 1489718-1488183 (Counterclockwise)

Preceding gene: 52841584

Following gene: 52841578

Centisome position: 43.84

GC content: 37.5

Gene sequence:

>1536_bases
ATGAAGCAGGCCGCTTTGATACATTCGACAATAATAAACACATCAACACTAAACCAATATTCGAAGTTCGTTGTTGTATT
TTTAGCAGGTTTATTAGCCCCCTTGGGGTTTGCACCTTTCCATCTGCCAGGATTAACTATTTTGAGTCTGGCCATTTTAT
TTTCTGAATTTCTTCAATGCACGGTTAAGCAGGGATTTTCCCTTGGTTTCCTATACGGGTTAGGATACTTTGGCTTCGGA
GTATCATGGGTGATTATCAGCATCCACGACTATGGACAACTTGATTACTTTCTTGCTGGCGTTATCACCTTATTGTTTAT
CATGTATCTTTCTCTGTTTCCTGGAATAGTCGGTTATTCCTTTAAACTCCTTTCAACCAAGTGTAATTTATTAACATGCA
TGCTTTTGTTTAGCACTCTTTGGTGTATAGCTGAGCTTATCCGTTCCAAGCTTTTTACTGGGTTCCCCTGGCTATTAGCA
GGTATAACCCAAATCGATACACCATTGAGATATATTGCACCAGTAGTTGGTGTTTATGGGCTTGGATTAATATGTTCTTT
TTTGGGTACCCTACTGGTTCTGATAATTAAAGACAATACGATTAAACGATATTACTACCTTAGCGTTTTTATCTTGATTC
TTATTGCACCATCACTGGGGAAAAATATCCATTGGACAGAAATCAAGAAAGAACCTATTTCTGTCGGTGCAATCCAGCCT
AATCTCTCAATGAGAGACAAGTGGGACGAAACTCTCTTTTGGGATTTATTAAAATACTATGAAAACAAAACAGATAAACT
GTTAGGAAAAAATTTAATTGTTTTACCCGAATCAGCCATACCCCTACCAGCAAGTTATGTTGAAGATTACCTACAGAAAC
TGCATGAAAAAGCATTAAAAGCCAAAAGCAGTTTAATTTTGGGAATCTTGCAACCTACAGATAATGATGAAACCAATTTT
TACAATTCCATCATTAGCTTGGGGGAAGCTACAGGAGCCTATGTGAAACGCCAATTGGTACCATTTGGAGAATATATACC
AAAACCCTTTATCCCCATCAATCGTTGGTTAAATCTTCCAGAACCTAATGTTGTTCCCGGCAGATCGAATCAGCCATTAA
TTAACATAGCTAATCATCCCATTGCCAGTCTAATTTGCTATGAAATTGCTTACCCAAATATCTTGAGATCACAAATGCCT
GCAGCTCAATGGATAGTCTCTATCAGTGATAATGGCTGGTTTGGCCATTCCCTGGCAAGCTACCAGCAATTACAAATGGC
TCAAATGCTCTCTTTGCTTACAGGACGATACCAAATTCTGGTGAATAATGATGGACTCTCCTCAGTAATTAACCACCAAG
GAACTATTGTCGAAGGGCTACCAGCTTTTAATTCAGGAATGCTCCAAACAGATATTTTTCCTGCAAATGGCATCACTCCC
TGGATAATTTGGAGTGACTATCCTACTTTTGTTTTTTGTTTCATATTTGTTCTTTTTGTTTTGTTTTTTAATATTAAACG
ATTTACAGAAAAATAA

Upstream 100 bases:

>100_bases
GATAGATCCAAAACATGATCAATACAGCAATTCTTGATATCACTTGACCAATTAGTCTTACTCATTTATCTTGACCACTT
TAATTTAGTCTAGTTGTGAC

Downstream 100 bases:

>100_bases
TCTATTGCTGGCAAAGGCAAGAGGGGTTATCCTTAGCAGTTCCGTGTTATTAAATTTATTGGCCTATGGATAATACCTAT
AACCCCCAAGAAGTTGAAGA

Product: apolipoprotein N-acyltransferase

Products: NA

Alternate protein names: ALP N-acyltransferase [H]

Number of amino acids: Translated: 511; Mature: 511

Protein sequence:

>511_residues
MKQAALIHSTIINTSTLNQYSKFVVVFLAGLLAPLGFAPFHLPGLTILSLAILFSEFLQCTVKQGFSLGFLYGLGYFGFG
VSWVIISIHDYGQLDYFLAGVITLLFIMYLSLFPGIVGYSFKLLSTKCNLLTCMLLFSTLWCIAELIRSKLFTGFPWLLA
GITQIDTPLRYIAPVVGVYGLGLICSFLGTLLVLIIKDNTIKRYYYLSVFILILIAPSLGKNIHWTEIKKEPISVGAIQP
NLSMRDKWDETLFWDLLKYYENKTDKLLGKNLIVLPESAIPLPASYVEDYLQKLHEKALKAKSSLILGILQPTDNDETNF
YNSIISLGEATGAYVKRQLVPFGEYIPKPFIPINRWLNLPEPNVVPGRSNQPLINIANHPIASLICYEIAYPNILRSQMP
AAQWIVSISDNGWFGHSLASYQQLQMAQMLSLLTGRYQILVNNDGLSSVINHQGTIVEGLPAFNSGMLQTDIFPANGITP
WIIWSDYPTFVFCFIFVLFVLFFNIKRFTEK

Sequences:

>Translated_511_residues
MKQAALIHSTIINTSTLNQYSKFVVVFLAGLLAPLGFAPFHLPGLTILSLAILFSEFLQCTVKQGFSLGFLYGLGYFGFG
VSWVIISIHDYGQLDYFLAGVITLLFIMYLSLFPGIVGYSFKLLSTKCNLLTCMLLFSTLWCIAELIRSKLFTGFPWLLA
GITQIDTPLRYIAPVVGVYGLGLICSFLGTLLVLIIKDNTIKRYYYLSVFILILIAPSLGKNIHWTEIKKEPISVGAIQP
NLSMRDKWDETLFWDLLKYYENKTDKLLGKNLIVLPESAIPLPASYVEDYLQKLHEKALKAKSSLILGILQPTDNDETNF
YNSIISLGEATGAYVKRQLVPFGEYIPKPFIPINRWLNLPEPNVVPGRSNQPLINIANHPIASLICYEIAYPNILRSQMP
AAQWIVSISDNGWFGHSLASYQQLQMAQMLSLLTGRYQILVNNDGLSSVINHQGTIVEGLPAFNSGMLQTDIFPANGITP
WIIWSDYPTFVFCFIFVLFVLFFNIKRFTEK
>Mature_511_residues
MKQAALIHSTIINTSTLNQYSKFVVVFLAGLLAPLGFAPFHLPGLTILSLAILFSEFLQCTVKQGFSLGFLYGLGYFGFG
VSWVIISIHDYGQLDYFLAGVITLLFIMYLSLFPGIVGYSFKLLSTKCNLLTCMLLFSTLWCIAELIRSKLFTGFPWLLA
GITQIDTPLRYIAPVVGVYGLGLICSFLGTLLVLIIKDNTIKRYYYLSVFILILIAPSLGKNIHWTEIKKEPISVGAIQP
NLSMRDKWDETLFWDLLKYYENKTDKLLGKNLIVLPESAIPLPASYVEDYLQKLHEKALKAKSSLILGILQPTDNDETNF
YNSIISLGEATGAYVKRQLVPFGEYIPKPFIPINRWLNLPEPNVVPGRSNQPLINIANHPIASLICYEIAYPNILRSQMP
AAQWIVSISDNGWFGHSLASYQQLQMAQMLSLLTGRYQILVNNDGLSSVINHQGTIVEGLPAFNSGMLQTDIFPANGITP
WIIWSDYPTFVFCFIFVLFVLFFNIKRFTEK

Specific function: Transfers the fatty acyl group on membrane lipoproteins [H]

COG id: COG0815

COG function: function code M; Apolipoprotein N-acyltransferase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 CN hydrolase domain [H]

Homologues:

Organism=Escherichia coli, GI1786878, Length=505, Percent_Identity=30.6930693069307, Blast_Score=230, Evalue=2e-61,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004563
- InterPro:   IPR003010 [H]

Pfam domain/function: PF00795 CN_hydrolase [H]

EC number: 2.3.1.- [C]

Molecular weight: Translated: 57471; Mature: 57471

Theoretical pI: Translated: 8.23; Mature: 8.23

Prosite motif: PS50263 CN_HYDROLASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKQAALIHSTIINTSTLNQYSKFVVVFLAGLLAPLGFAPFHLPGLTILSLAILFSEFLQC
CCCHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHH
TVKQGFSLGFLYGLGYFGFGVSWVIISIHDYGQLDYFLAGVITLLFIMYLSLFPGIVGYS
HHHCCCCHHHHHHHHHHHHCEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
FKLLSTKCNLLTCMLLFSTLWCIAELIRSKLFTGFPWLLAGITQIDTPLRYIAPVVGVYG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCHHHHHHHHHHHH
LGLICSFLGTLLVLIIKDNTIKRYYYLSVFILILIAPSLGKNIHWTEIKKEPISVGAIQP
HHHHHHHHHHHHEEHCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEHHHCCCCCEEEEECC
NLSMRDKWDETLFWDLLKYYENKTDKLLGKNLIVLPESAIPLPASYVEDYLQKLHEKALK
CCCCCCCHHHHHHHHHHHHHHCCHHHHHCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHH
AKSSLILGILQPTDNDETNFYNSIISLGEATGAYVKRQLVPFGEYIPKPFIPINRWLNLP
HHHHEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCCHHHCCCCC
EPNVVPGRSNQPLINIANHPIASLICYEIAYPNILRSQMPAAQWIVSISDNGWFGHSLAS
CCCCCCCCCCCCEEEECCCHHHHHHHHHHHCHHHHHHHCCHHHEEEEECCCCCCCHHHHH
YQQLQMAQMLSLLTGRYQILVNNDGLSSVINHQGTIVEGLPAFNSGMLQTDIFPANGITP
HHHHHHHHHHHHHCCCEEEEECCCCHHHHHCCCCCEEECCCCCCCCCEEECCCCCCCCCC
WIIWSDYPTFVFCFIFVLFVLFFNIKRFTEK
EEEECCCHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKQAALIHSTIINTSTLNQYSKFVVVFLAGLLAPLGFAPFHLPGLTILSLAILFSEFLQC
CCCHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHH
TVKQGFSLGFLYGLGYFGFGVSWVIISIHDYGQLDYFLAGVITLLFIMYLSLFPGIVGYS
HHHCCCCHHHHHHHHHHHHCEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
FKLLSTKCNLLTCMLLFSTLWCIAELIRSKLFTGFPWLLAGITQIDTPLRYIAPVVGVYG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCHHHHHHHHHHHH
LGLICSFLGTLLVLIIKDNTIKRYYYLSVFILILIAPSLGKNIHWTEIKKEPISVGAIQP
HHHHHHHHHHHHEEHCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEHHHCCCCCEEEEECC
NLSMRDKWDETLFWDLLKYYENKTDKLLGKNLIVLPESAIPLPASYVEDYLQKLHEKALK
CCCCCCCHHHHHHHHHHHHHHCCHHHHHCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHH
AKSSLILGILQPTDNDETNFYNSIISLGEATGAYVKRQLVPFGEYIPKPFIPINRWLNLP
HHHHEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCCHHHCCCCC
EPNVVPGRSNQPLINIANHPIASLICYEIAYPNILRSQMPAAQWIVSISDNGWFGHSLAS
CCCCCCCCCCCCEEEECCCHHHHHHHHHHHCHHHHHHHCCHHHEEEEECCCCCCCHHHHH
YQQLQMAQMLSLLTGRYQILVNNDGLSSVINHQGTIVEGLPAFNSGMLQTDIFPANGITP
HHHHHHHHHHHHHCCCEEEEECCCCHHHHHCCCCCEEECCCCCCCCCEEECCCCCCCCCC
WIIWSDYPTFVFCFIFVLFVLFFNIKRFTEK
EEEECCCHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Transferases; Acyltransferases; Transferring groups other than amino-acyl groups [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12704232 [H]