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The map label for this gene is cysS

Identifier: 52841538

GI number: 52841538

Start: 1436305

End: 1437675

Strand: Direct

Name: cysS

Synonym: lpg1307

Alternate gene names: 52841538

Gene position: 1436305-1437675 (Clockwise)

Preceding gene: 52841537

Following gene: 52841539

Centisome position: 42.27

GC content: 40.92

Gene sequence:

>1371_bases
ATGTTACATTTATATAATTCTTTGACCAGAAAAAAAGAACCATTTGTTTCCTTAAAGCCCGGAACGATAGGTATGTATGT
ATGCGGAATTACTGTGTATGACCACTGCCACTTAGGGCATGCCCGTTCAATGGTTGCCTTTGATGTAATGGTTCGTTATC
TGCGCTCACAAGGATTCGATGTAACTTATGTACGCAATATAACTGACATAGATGATAAAATCATCGCAAGAGCCTCGGAG
AGAGGTGTATCTATTGATGAATTGACCGCACAATATATTGATGCAATGAATAATGATACTCATGCATTAAATATTTTGCC
ACCTGACCATGAGCCAAGGGCAACCGGGCACATTGAAACTATCATTCGCTTGATTCAACGTTTGCTTGAAAAAGGTAACG
CGTATGTCAGTGAGAATGGCGATGTGTGCTATGAAGTAGATACCTTTCCCGAATATGGGAAATTATCGCATAAAGATATT
GAAGGCTTGGTTTCGGGTTCTCGCGTAGAGATTGTAAAAGAGAAACGTTCACCGCTTGATTTTGTGCTATGGAAAAAAGC
AAAACCGGGTGAACCCAGTTGGCCTTCACCGTGGGGGGAAGGGCGGCCTGGATGGCACATTGAGTGTTCAGCTATGGCTA
TGCATGAATTAGGTGAACAATTTGATATTCATGGAGGTGGATTGGATTTGCAATTCCCACATCATGAAAATGAAATTGCT
CAAAGTGAAGCGGCTACGGGTAAACCTTTTGCTAATTATTGGCTGCATGTCGGAATGTTGCAGGTTAATGGCGAAAAAAT
GGCAAAATCAATAGGGAACTTTTACACTATTGCCGATGTTTTAAAAGAGCATCATCCGGAAGTCATCCGCTATTTTCTAT
TAAGTAGTCATTATCGCAGTCCTTTGAATTATTCAGAAGAAAATTTGTTAAATGCCAAAAAAGCCCTTATCAGGCTTTAT
CAAGCGGTTAAAGATGTTCCGCCACAAACCGAAGATAGTAAACTGGATGAGTATTGGCAAGTGCAATTTAATCAGGCAAT
GAATGATGATTTCAATACTCCTGTTGCATTATCGGTTCTTTTCCAATTGGCTCATGAGGTAAACAAAAGTAATTCACCTG
CATTGGCTCATACCCTGAAAAACCTTGCTGGTATTCTTGGATTTTTACAAAAAGATCCCGAATCATTCTTGCAATCCGGT
TTGGCAGAGGAAGAAAAATTGGTTATAGAACAACTCATTGCCGAGCGTCTTCAGGCGCGAGCGGAACGCAATTGGGCAAA
GGCAGATCAGATTAGAGCTGATTTATTGAGCAAAGGCATAGAGCTGGAAGATGGTGCAACAGGAACAACATGGCGGAGGA
TTGCTGAATAA

Upstream 100 bases:

>100_bases
TTATTATTGCGTCAATTCAGTGGCTGAGGGCTGTGTTCAAGCCTTTCATCGGGTAGTGGATTTGAAGGACACTTGGGGTA
AAGTGAGTTGAGAGGCAGAC

Downstream 100 bases:

>100_bases
TTGTTCCTTCTATGCGCTTCTCTTGAATCAGAATGGACTTCTATCTCATACTTAATATAGACTGCGATTACCTTTTCAGA
AATTTTAAATCAGGTATATT

Product: cysteinyl-tRNA synthetase

Products: NA

Alternate protein names: Cysteine--tRNA ligase; CysRS [H]

Number of amino acids: Translated: 456; Mature: 456

Protein sequence:

>456_residues
MLHLYNSLTRKKEPFVSLKPGTIGMYVCGITVYDHCHLGHARSMVAFDVMVRYLRSQGFDVTYVRNITDIDDKIIARASE
RGVSIDELTAQYIDAMNNDTHALNILPPDHEPRATGHIETIIRLIQRLLEKGNAYVSENGDVCYEVDTFPEYGKLSHKDI
EGLVSGSRVEIVKEKRSPLDFVLWKKAKPGEPSWPSPWGEGRPGWHIECSAMAMHELGEQFDIHGGGLDLQFPHHENEIA
QSEAATGKPFANYWLHVGMLQVNGEKMAKSIGNFYTIADVLKEHHPEVIRYFLLSSHYRSPLNYSEENLLNAKKALIRLY
QAVKDVPPQTEDSKLDEYWQVQFNQAMNDDFNTPVALSVLFQLAHEVNKSNSPALAHTLKNLAGILGFLQKDPESFLQSG
LAEEEKLVIEQLIAERLQARAERNWAKADQIRADLLSKGIELEDGATGTTWRRIAE

Sequences:

>Translated_456_residues
MLHLYNSLTRKKEPFVSLKPGTIGMYVCGITVYDHCHLGHARSMVAFDVMVRYLRSQGFDVTYVRNITDIDDKIIARASE
RGVSIDELTAQYIDAMNNDTHALNILPPDHEPRATGHIETIIRLIQRLLEKGNAYVSENGDVCYEVDTFPEYGKLSHKDI
EGLVSGSRVEIVKEKRSPLDFVLWKKAKPGEPSWPSPWGEGRPGWHIECSAMAMHELGEQFDIHGGGLDLQFPHHENEIA
QSEAATGKPFANYWLHVGMLQVNGEKMAKSIGNFYTIADVLKEHHPEVIRYFLLSSHYRSPLNYSEENLLNAKKALIRLY
QAVKDVPPQTEDSKLDEYWQVQFNQAMNDDFNTPVALSVLFQLAHEVNKSNSPALAHTLKNLAGILGFLQKDPESFLQSG
LAEEEKLVIEQLIAERLQARAERNWAKADQIRADLLSKGIELEDGATGTTWRRIAE
>Mature_456_residues
MLHLYNSLTRKKEPFVSLKPGTIGMYVCGITVYDHCHLGHARSMVAFDVMVRYLRSQGFDVTYVRNITDIDDKIIARASE
RGVSIDELTAQYIDAMNNDTHALNILPPDHEPRATGHIETIIRLIQRLLEKGNAYVSENGDVCYEVDTFPEYGKLSHKDI
EGLVSGSRVEIVKEKRSPLDFVLWKKAKPGEPSWPSPWGEGRPGWHIECSAMAMHELGEQFDIHGGGLDLQFPHHENEIA
QSEAATGKPFANYWLHVGMLQVNGEKMAKSIGNFYTIADVLKEHHPEVIRYFLLSSHYRSPLNYSEENLLNAKKALIRLY
QAVKDVPPQTEDSKLDEYWQVQFNQAMNDDFNTPVALSVLFQLAHEVNKSNSPALAHTLKNLAGILGFLQKDPESFLQSG
LAEEEKLVIEQLIAERLQARAERNWAKADQIRADLLSKGIELEDGATGTTWRRIAE

Specific function: Unknown

COG id: COG0215

COG function: function code J; Cysteinyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI13375695, Length=386, Percent_Identity=41.7098445595855, Blast_Score=276, Evalue=2e-74,
Organism=Homo sapiens, GI10835051, Length=249, Percent_Identity=44.9799196787149, Blast_Score=207, Evalue=2e-53,
Organism=Homo sapiens, GI21269877, Length=249, Percent_Identity=44.9799196787149, Blast_Score=207, Evalue=2e-53,
Organism=Homo sapiens, GI62240992, Length=249, Percent_Identity=44.9799196787149, Blast_Score=207, Evalue=2e-53,
Organism=Homo sapiens, GI303304987, Length=249, Percent_Identity=44.9799196787149, Blast_Score=207, Evalue=2e-53,
Organism=Escherichia coli, GI1786737, Length=461, Percent_Identity=55.9652928416486, Blast_Score=514, Evalue=1e-147,
Organism=Caenorhabditis elegans, GI17509795, Length=264, Percent_Identity=39.3939393939394, Blast_Score=189, Evalue=2e-48,
Organism=Caenorhabditis elegans, GI17509797, Length=264, Percent_Identity=39.3939393939394, Blast_Score=189, Evalue=2e-48,
Organism=Saccharomyces cerevisiae, GI6324082, Length=339, Percent_Identity=34.2182890855457, Blast_Score=188, Evalue=1e-48,
Organism=Drosophila melanogaster, GI19922218, Length=501, Percent_Identity=34.1317365269461, Blast_Score=261, Evalue=7e-70,
Organism=Drosophila melanogaster, GI19922364, Length=309, Percent_Identity=38.5113268608414, Blast_Score=198, Evalue=7e-51,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015803
- InterPro:   IPR015273
- InterPro:   IPR014729
- InterPro:   IPR009080 [H]

Pfam domain/function: PF09190 DALR_2; PF01406 tRNA-synt_1e [H]

EC number: =6.1.1.16 [H]

Molecular weight: Translated: 51558; Mature: 51558

Theoretical pI: Translated: 5.90; Mature: 5.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLHLYNSLTRKKEPFVSLKPGTIGMYVCGITVYDHCHLGHARSMVAFDVMVRYLRSQGFD
CCCHHHHHHHCCCCCEEECCCCEEEEEEEEHHHHHHCCCHHHHHHHHHHHHHHHHHCCCC
VTYVRNITDIDDKIIARASERGVSIDELTAQYIDAMNNDTHALNILPPDHEPRATGHIET
EEEECCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCHHHH
IIRLIQRLLEKGNAYVSENGDVCYEVDTFPEYGKLSHKDIEGLVSGSRVEIVKEKRSPLD
HHHHHHHHHHCCCEEEECCCCEEEEECCCCCCCCCCHHHHHHHHCCCHHHHHHHCCCCCC
FVLWKKAKPGEPSWPSPWGEGRPGWHIECSAMAMHELGEQFDIHGGGLDLQFPHHENEIA
EEEECCCCCCCCCCCCCCCCCCCCCEEEHHHHHHHHCCHHEECCCCCEEEECCCCHHHHH
QSEAATGKPFANYWLHVGMLQVNGEKMAKSIGNFYTIADVLKEHHPEVIRYFLLSSHYRS
HHHCCCCCCHHHHHHEEEEEEECHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCC
PLNYSEENLLNAKKALIRLYQAVKDVPPQTEDSKLDEYWQVQFNQAMNDDFNTPVALSVL
CCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHH
FQLAHEVNKSNSPALAHTLKNLAGILGFLQKDPESFLQSGLAEEEKLVIEQLIAERLQAR
HHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHCCCCHHHHHHHHHHHHHHHHHH
AERNWAKADQIRADLLSKGIELEDGATGTTWRRIAE
HHHCHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHCC
>Mature Secondary Structure
MLHLYNSLTRKKEPFVSLKPGTIGMYVCGITVYDHCHLGHARSMVAFDVMVRYLRSQGFD
CCCHHHHHHHCCCCCEEECCCCEEEEEEEEHHHHHHCCCHHHHHHHHHHHHHHHHHCCCC
VTYVRNITDIDDKIIARASERGVSIDELTAQYIDAMNNDTHALNILPPDHEPRATGHIET
EEEECCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCHHHH
IIRLIQRLLEKGNAYVSENGDVCYEVDTFPEYGKLSHKDIEGLVSGSRVEIVKEKRSPLD
HHHHHHHHHHCCCEEEECCCCEEEEECCCCCCCCCCHHHHHHHHCCCHHHHHHHCCCCCC
FVLWKKAKPGEPSWPSPWGEGRPGWHIECSAMAMHELGEQFDIHGGGLDLQFPHHENEIA
EEEECCCCCCCCCCCCCCCCCCCCCEEEHHHHHHHHCCHHEECCCCCEEEECCCCHHHHH
QSEAATGKPFANYWLHVGMLQVNGEKMAKSIGNFYTIADVLKEHHPEVIRYFLLSSHYRS
HHHCCCCCCHHHHHHEEEEEEECHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCC
PLNYSEENLLNAKKALIRLYQAVKDVPPQTEDSKLDEYWQVQFNQAMNDDFNTPVALSVL
CCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHH
FQLAHEVNKSNSPALAHTLKNLAGILGFLQKDPESFLQSGLAEEEKLVIEQLIAERLQAR
HHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHCCCCHHHHHHHHHHHHHHHHHH
AERNWAKADQIRADLLSKGIELEDGATGTTWRRIAE
HHHCHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA