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The map label for this gene is dtpA [H]

Identifier: 52841496

GI number: 52841496

Start: 1390448

End: 1391935

Strand: Reverse

Name: dtpA [H]

Synonym: lpg1264

Alternate gene names: 52841496

Gene position: 1391935-1390448 (Counterclockwise)

Preceding gene: 52841498

Following gene: 52841493

Centisome position: 40.97

GC content: 34.01

Gene sequence:

>1488_bases
ATGAGTACTGTAGAGCAAAGAATGCCTAAAGGTATAATGTCTCTTTATTTAATACAAATGTTTTCCACATTCTCATTTGC
AGTGCTTTATTCCTCATTGTCCTTGTACATCACTAACCAACTAGGTTTATCAAACCACATATCCAATAGTATTGTTGGGT
TATTTTTAGCATTTAATTTCGTTTTGCATCTATTTGGCGGGCTAATAGGCGGCAATTGGTTAAGTAATCGATTTCTTTTC
TTATTCACTACTATTTTGCAAACCTTTGGCATTCTATGCCTAGTATTTCCAGAAACCCCCTCACTTTATCTAGGATTGAG
TTTGTTTTTAATCGGCTGCGGATTAAATACAACGTGTTATAACACGATTCTCACCCAACGTTTTTCATCTTCCGATCCAA
GACGAGACAAAGCTTTTTTTATGAGCTATTCCACTATGAATATAGGCTTTTGGGCTGGTTTTATTTGTAGTGGCTTTTAT
GATGCCTCCAATCACTACGAAGAAATTTTCTACGCTAGTATAGCAACTAACATAATTACCACATTATTAGTTCTCTATTG
CTGGAAAAACATAACTGACATAAATACCGCCCTAGCCTTAAACCCTGCGCAAAAACAAAGAATAAAAGGTATTGGAGGTA
TTTTATTTATATTACTTCTCATACCTGTCTTGAATATTTGCTTTAAGTTACCTGATTTTAGTAATGGCTTAGTAATAACG
ATTAGTGTGCTAATGTTCTTCGTTATTTTATTTATCAGAAACAATCAAAAAATACTCTCAGACAGACAAAAAATTACTGC
CTTTTTAATTTTAACCATTACATCAACTGTGTTTTGGATGATTTATTATACGGGTCCAATGGGTATTACTTTGTTTATTA
AAAATAATGTTGATAAACAACTTTTAGGTTTTGAAATTCCCACACAATGGATTCTAAATATTAACTCCGTAGTTATCATT
ATTGGCAGCCCGTTGATCGCGTTACTAATTAGCAAACTACAGAATAAAGGTTACACGTTTTCTGTTTCAACCCAATTCAT
TTGGGCATTTCTTTTCTTAACGATATCATTCTTTTCTTTATCATGTGGAATTCATTTTGCTAATGAAGCAGGCTATACGG
CTTTTAGCTGGATTATTTTGCATTTAGTGACCCAAGCAGTAGCGGAATTATTTATAGGACCTGTGGGCTATGCAATGATT
GGCCGTATAGCTCCAAACCATTTACAAGGGCTTCTAATGGGAAGCTGGATGCTTGTTTCAGGTGTATCTGCATCCTTATC
TCATTATTTTTCGAATTCAATGATTCAATCTGAATCATCAGATCCTTTGTTAAGTAATTCAGATTATTATCACGTATTTA
ATGAGCTCGCAGTGTGGGGATTAGCAGGCGCACTATTTTTGTATTTAATTGCAGGAAAATTACGTTTATTCATGAATGAA
AGGTCAAATAAAAATGATTCCGCATCTCCTGAGTTACTTCATCAATAG

Upstream 100 bases:

>100_bases
ACTTGTTCCACTCGTGAACAGTATTACATCAAAAATTAAAAAAACACTTAATCTTAACTAATTCTAATGTTAGAGTCACG
GCTCACGGATAGGAGGTCAA

Downstream 100 bases:

>100_bases
AAATAATTTTTTTAAGATGATTACAATTAAAACAAAATTACATTTTACCTCTATCATTTTCCAAGCAAAAAACATAATTT
TATTCTCTGACTCGCTATGT

Product: proton/peptide symporter family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 495; Mature: 494

Protein sequence:

>495_residues
MSTVEQRMPKGIMSLYLIQMFSTFSFAVLYSSLSLYITNQLGLSNHISNSIVGLFLAFNFVLHLFGGLIGGNWLSNRFLF
LFTTILQTFGILCLVFPETPSLYLGLSLFLIGCGLNTTCYNTILTQRFSSSDPRRDKAFFMSYSTMNIGFWAGFICSGFY
DASNHYEEIFYASIATNIITTLLVLYCWKNITDINTALALNPAQKQRIKGIGGILFILLLIPVLNICFKLPDFSNGLVIT
ISVLMFFVILFIRNNQKILSDRQKITAFLILTITSTVFWMIYYTGPMGITLFIKNNVDKQLLGFEIPTQWILNINSVVII
IGSPLIALLISKLQNKGYTFSVSTQFIWAFLFLTISFFSLSCGIHFANEAGYTAFSWIILHLVTQAVAELFIGPVGYAMI
GRIAPNHLQGLLMGSWMLVSGVSASLSHYFSNSMIQSESSDPLLSNSDYYHVFNELAVWGLAGALFLYLIAGKLRLFMNE
RSNKNDSASPELLHQ

Sequences:

>Translated_495_residues
MSTVEQRMPKGIMSLYLIQMFSTFSFAVLYSSLSLYITNQLGLSNHISNSIVGLFLAFNFVLHLFGGLIGGNWLSNRFLF
LFTTILQTFGILCLVFPETPSLYLGLSLFLIGCGLNTTCYNTILTQRFSSSDPRRDKAFFMSYSTMNIGFWAGFICSGFY
DASNHYEEIFYASIATNIITTLLVLYCWKNITDINTALALNPAQKQRIKGIGGILFILLLIPVLNICFKLPDFSNGLVIT
ISVLMFFVILFIRNNQKILSDRQKITAFLILTITSTVFWMIYYTGPMGITLFIKNNVDKQLLGFEIPTQWILNINSVVII
IGSPLIALLISKLQNKGYTFSVSTQFIWAFLFLTISFFSLSCGIHFANEAGYTAFSWIILHLVTQAVAELFIGPVGYAMI
GRIAPNHLQGLLMGSWMLVSGVSASLSHYFSNSMIQSESSDPLLSNSDYYHVFNELAVWGLAGALFLYLIAGKLRLFMNE
RSNKNDSASPELLHQ
>Mature_494_residues
STVEQRMPKGIMSLYLIQMFSTFSFAVLYSSLSLYITNQLGLSNHISNSIVGLFLAFNFVLHLFGGLIGGNWLSNRFLFL
FTTILQTFGILCLVFPETPSLYLGLSLFLIGCGLNTTCYNTILTQRFSSSDPRRDKAFFMSYSTMNIGFWAGFICSGFYD
ASNHYEEIFYASIATNIITTLLVLYCWKNITDINTALALNPAQKQRIKGIGGILFILLLIPVLNICFKLPDFSNGLVITI
SVLMFFVILFIRNNQKILSDRQKITAFLILTITSTVFWMIYYTGPMGITLFIKNNVDKQLLGFEIPTQWILNINSVVIII
GSPLIALLISKLQNKGYTFSVSTQFIWAFLFLTISFFSLSCGIHFANEAGYTAFSWIILHLVTQAVAELFIGPVGYAMIG
RIAPNHLQGLLMGSWMLVSGVSASLSHYFSNSMIQSESSDPLLSNSDYYHVFNELAVWGLAGALFLYLIAGKLRLFMNER
SNKNDSASPELLHQ

Specific function: Proton-dependent permease that transports di- and tripeptides [H]

COG id: COG3104

COG function: function code E; Dipeptide/tripeptide permease

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PTR2/POT transporter (TC 2.A.17) family. DtpA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787922, Length=475, Percent_Identity=25.2631578947368, Blast_Score=156, Evalue=3e-39,
Organism=Escherichia coli, GI1789911, Length=480, Percent_Identity=23.9583333333333, Blast_Score=139, Evalue=4e-34,
Organism=Escherichia coli, GI1790572, Length=492, Percent_Identity=24.7967479674797, Blast_Score=128, Evalue=9e-31,
Organism=Escherichia coli, GI1786927, Length=462, Percent_Identity=24.025974025974, Blast_Score=125, Evalue=5e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR016196
- InterPro:   IPR000109
- InterPro:   IPR005279
- InterPro:   IPR018456 [H]

Pfam domain/function: PF00854 PTR2 [H]

EC number: NA

Molecular weight: Translated: 55489; Mature: 55358

Theoretical pI: Translated: 8.43; Mature: 8.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTVEQRMPKGIMSLYLIQMFSTFSFAVLYSSLSLYITNQLGLSNHISNSIVGLFLAFNF
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCHHHHHHHHHHHHHHHHH
VLHLFGGLIGGNWLSNRFLFLFTTILQTFGILCLVFPETPSLYLGLSLFLIGCGLNTTCY
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHCEEEEEECCCCCHHHHHHHHHHHCCCCHHHH
NTILTQRFSSSDPRRDKAFFMSYSTMNIGFWAGFICSGFYDASNHYEEIFYASIATNIIT
HHHHHHHHCCCCCCCCCEEEEEEECCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHH
TLLVLYCWKNITDINTALALNPAQKQRIKGIGGILFILLLIPVLNICFKLPDFSNGLVIT
HHHHHHHHCCCCCCCHHEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHH
ISVLMFFVILFIRNNQKILSDRQKITAFLILTITSTVFWMIYYTGPMGITLFIKNNVDKQ
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCEEEEEEECCCCHH
LLGFEIPTQWILNINSVVIIIGSPLIALLISKLQNKGYTFSVSTQFIWAFLFLTISFFSL
HHCCCCCHHHHEECCEEEEEECCHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHH
SCGIHFANEAGYTAFSWIILHLVTQAVAELFIGPVGYAMIGRIAPNHLQGLLMGSWMLVS
HCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHCHHHHHHHHCCCHHHHHHHHHHHHHHHH
GVSASLSHYFSNSMIQSESSDPLLSNSDYYHVFNELAVWGLAGALFLYLIAGKLRLFMNE
HHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
RSNKNDSASPELLHQ
CCCCCCCCCCHHHCC
>Mature Secondary Structure 
STVEQRMPKGIMSLYLIQMFSTFSFAVLYSSLSLYITNQLGLSNHISNSIVGLFLAFNF
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCHHHHHHHHHHHHHHHHH
VLHLFGGLIGGNWLSNRFLFLFTTILQTFGILCLVFPETPSLYLGLSLFLIGCGLNTTCY
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHCEEEEEECCCCCHHHHHHHHHHHCCCCHHHH
NTILTQRFSSSDPRRDKAFFMSYSTMNIGFWAGFICSGFYDASNHYEEIFYASIATNIIT
HHHHHHHHCCCCCCCCCEEEEEEECCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHH
TLLVLYCWKNITDINTALALNPAQKQRIKGIGGILFILLLIPVLNICFKLPDFSNGLVIT
HHHHHHHHCCCCCCCHHEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHH
ISVLMFFVILFIRNNQKILSDRQKITAFLILTITSTVFWMIYYTGPMGITLFIKNNVDKQ
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCEEEEEEECCCCHH
LLGFEIPTQWILNINSVVIIIGSPLIALLISKLQNKGYTFSVSTQFIWAFLFLTISFFSL
HHCCCCCHHHHEECCEEEEEECCHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHH
SCGIHFANEAGYTAFSWIILHLVTQAVAELFIGPVGYAMIGRIAPNHLQGLLMGSWMLVS
HCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHCHHHHHHHHCCCHHHHHHHHHHHHHHHH
GVSASLSHYFSNSMIQSESSDPLLSNSDYYHVFNELAVWGLAGALFLYLIAGKLRLFMNE
HHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
RSNKNDSASPELLHQ
CCCCCCCCCCHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA