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The map label for this gene is argE

Identifier: 52841398

GI number: 52841398

Start: 1283991

End: 1285145

Strand: Direct

Name: argE

Synonym: lpg1164

Alternate gene names: 52841398

Gene position: 1283991-1285145 (Clockwise)

Preceding gene: 52841397

Following gene: 52841399

Centisome position: 37.79

GC content: 38.35

Gene sequence:

>1155_bases
ATGACAACTTTAGATTGGTTAAAACAACTCATTTCTTTTGATACTACTTCGCGGAACTCTAATTTATCATTGATTGAATA
TTTGGCGAATGGGTTAAATGATTTCAAGATTAATCCTATCCTAATTCACGATAGTAAAGAGCAGAAAGCTAATCTGTTAG
CTACTTTGCCAGGAAAACAAGGGCGTTTGGAAGGGGGTATTATTCTGTCTGGTCATACTGATGTTGTTCCTGTTGACGGT
CAAATTTGGGATAGTGATCCTTTTCAAGCCACTGTTAAAAATAACAAAGTGTATGGTCGTGGCGCGTGTGACATGAAAGG
ATTTATTGCAGTCGTGATGGCTTTAGTCCCACAATTGAAAGAAATGAACCTGGATTTTCCAGTTCATTTTGCATTTTCTT
ATGATGAGGAAATTGGTTGTCTTGGTGTGCCTTCTCTCATCGATAAAATAGTGGAGCTTAATTATCAACCGCGTGCTTGC
ATTGTAGGTGAGCCAACCTTAATGAAGCCTGTTGTGGGTCATAAAGGCAAATATTCTTATCGCTGCCAAATACATGGTGT
AGCTGCCCATTCTTCATTAACGAATCAAGGATGTAATGCGATCGAACATGCCGCGTCTTTTATAAGCTATCTTCGAGGGA
TGGCTAATGAATTTAAAAAATATGGAAATCGAGATTTTTCTTATGATGTTCCATATACAACACTTACCACTAATCTCATC
AAAGGAGGTAATGCTTATAATACTATTCCAAACTTGTGTGAGTTTGTTTTTGAATTTAGAAATCTGTCTACTGACAGCTC
AGAGGATTTAAATCAGAAAATTATGTCTTATGTTAAGGAAGAGCTTGCTCCTAGCCTGCATCAGGACCATCCTGACTCTA
ATGTTAACCTTGATACGATAGCAAAAGCTCCTGGTTTGGATATGCCGATTACAGATCCTTTTGTCAGAGCAGCTCAAACA
GTTTGCCAGAGCGATAAGCTGATGAAAGTAGCTTACGCTACAGAAGCCGGGCTATTTCAACAGGCAGAAATTCCTACTAT
TGTGTGTGGTCCAGGTAGTATCGAACAAGCCCATAGAGCAAATGAATATGTTGAAGTAGAGCAATTACGATTATGTGAGG
AATTTATAATCAATATGCTGCGCTCTCATTTTTGA

Upstream 100 bases:

>100_bases
CGGTCTTTATCAGTTTGCTAGCAGTCCTTGCTTATCAGGAGGAAAGGAAGCTATCTGAGAATCAGCCAGAACATCTCGTT
GCAATTTAAAAGGTAGGAAT

Downstream 100 bases:

>100_bases
GCTTTATCAGATTGGTAAGTAAAAAATCATCGGTATTTGATGCTGATTTTACTAGCACTTTTATAAGGTATTCACAAAGA
TATACACAGTTTTTGTGGAT

Product: acetylornithine deacetylase

Products: NA

Alternate protein names: AO; Acetylornithinase; N-acetylornithinase; NAO [H]

Number of amino acids: Translated: 384; Mature: 383

Protein sequence:

>384_residues
MTTLDWLKQLISFDTTSRNSNLSLIEYLANGLNDFKINPILIHDSKEQKANLLATLPGKQGRLEGGIILSGHTDVVPVDG
QIWDSDPFQATVKNNKVYGRGACDMKGFIAVVMALVPQLKEMNLDFPVHFAFSYDEEIGCLGVPSLIDKIVELNYQPRAC
IVGEPTLMKPVVGHKGKYSYRCQIHGVAAHSSLTNQGCNAIEHAASFISYLRGMANEFKKYGNRDFSYDVPYTTLTTNLI
KGGNAYNTIPNLCEFVFEFRNLSTDSSEDLNQKIMSYVKEELAPSLHQDHPDSNVNLDTIAKAPGLDMPITDPFVRAAQT
VCQSDKLMKVAYATEAGLFQQAEIPTIVCGPGSIEQAHRANEYVEVEQLRLCEEFIINMLRSHF

Sequences:

>Translated_384_residues
MTTLDWLKQLISFDTTSRNSNLSLIEYLANGLNDFKINPILIHDSKEQKANLLATLPGKQGRLEGGIILSGHTDVVPVDG
QIWDSDPFQATVKNNKVYGRGACDMKGFIAVVMALVPQLKEMNLDFPVHFAFSYDEEIGCLGVPSLIDKIVELNYQPRAC
IVGEPTLMKPVVGHKGKYSYRCQIHGVAAHSSLTNQGCNAIEHAASFISYLRGMANEFKKYGNRDFSYDVPYTTLTTNLI
KGGNAYNTIPNLCEFVFEFRNLSTDSSEDLNQKIMSYVKEELAPSLHQDHPDSNVNLDTIAKAPGLDMPITDPFVRAAQT
VCQSDKLMKVAYATEAGLFQQAEIPTIVCGPGSIEQAHRANEYVEVEQLRLCEEFIINMLRSHF
>Mature_383_residues
TTLDWLKQLISFDTTSRNSNLSLIEYLANGLNDFKINPILIHDSKEQKANLLATLPGKQGRLEGGIILSGHTDVVPVDGQ
IWDSDPFQATVKNNKVYGRGACDMKGFIAVVMALVPQLKEMNLDFPVHFAFSYDEEIGCLGVPSLIDKIVELNYQPRACI
VGEPTLMKPVVGHKGKYSYRCQIHGVAAHSSLTNQGCNAIEHAASFISYLRGMANEFKKYGNRDFSYDVPYTTLTTNLIK
GGNAYNTIPNLCEFVFEFRNLSTDSSEDLNQKIMSYVKEELAPSLHQDHPDSNVNLDTIAKAPGLDMPITDPFVRAAQTV
CQSDKLMKVAYATEAGLFQQAEIPTIVCGPGSIEQAHRANEYVEVEQLRLCEEFIINMLRSHF

Specific function: Displays A Broad Specificity And Can Also Deacylate Substrates Such As Acetylarginine, Acetylhistidine Or Acetylglutamate Semialdehyde. [C]

COG id: COG0624

COG function: function code E; Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M20A family. ArgE subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790395, Length=369, Percent_Identity=32.520325203252, Blast_Score=168, Evalue=5e-43,
Organism=Escherichia coli, GI1788816, Length=227, Percent_Identity=28.6343612334802, Blast_Score=85, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24649206, Length=296, Percent_Identity=22.6351351351351, Blast_Score=66, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010169
- InterPro:   IPR001261
- InterPro:   IPR002933
- InterPro:   IPR011650 [H]

Pfam domain/function: PF07687 M20_dimer; PF01546 Peptidase_M20 [H]

EC number: =3.5.1.16 [H]

Molecular weight: Translated: 42707; Mature: 42576

Theoretical pI: Translated: 5.39; Mature: 5.39

Prosite motif: PS00759 ARGE_DAPE_CPG2_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTLDWLKQLISFDTTSRNSNLSLIEYLANGLNDFKINPILIHDSKEQKANLLATLPGKQ
CCHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCCCCCCCEEEEECCCHHHCCEEEECCCCC
GRLEGGIILSGHTDVVPVDGQIWDSDPFQATVKNNKVYGRGACDMKGFIAVVMALVPQLK
CCCCCCEEEECCCCEEECCCEECCCCCCEEEECCCEEECCCCCCHHHHHHHHHHHHHHHH
EMNLDFPVHFAFSYDEEIGCLGVPSLIDKIVELNYQPRACIVGEPTLMKPVVGHKGKYSY
HCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHCCCCCCEEEECCCHHHHHHCCCCCCEEE
RCQIHGVAAHSSLTNQGCNAIEHAASFISYLRGMANEFKKYGNRDFSYDVPYTTLTTNLI
EEEEEEEEHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHH
KGGNAYNTIPNLCEFVFEFRNLSTDSSEDLNQKIMSYVKEELAPSLHQDHPDSNVNLDTI
CCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCHHHHCCCCCCCCCHHHH
AKAPGLDMPITDPFVRAAQTVCQSDKLMKVAYATEAGLFQQAEIPTIVCGPGSIEQAHRA
CCCCCCCCCCCCHHHHHHHHHHCCCCCEEEEHHHHCCCCCCCCCCEEEECCCCHHHHHHH
NEYVEVEQLRLCEEFIINMLRSHF
HHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TTLDWLKQLISFDTTSRNSNLSLIEYLANGLNDFKINPILIHDSKEQKANLLATLPGKQ
CHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCCCCCCCEEEEECCCHHHCCEEEECCCCC
GRLEGGIILSGHTDVVPVDGQIWDSDPFQATVKNNKVYGRGACDMKGFIAVVMALVPQLK
CCCCCCEEEECCCCEEECCCEECCCCCCEEEECCCEEECCCCCCHHHHHHHHHHHHHHHH
EMNLDFPVHFAFSYDEEIGCLGVPSLIDKIVELNYQPRACIVGEPTLMKPVVGHKGKYSY
HCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHCCCCCCEEEECCCHHHHHHCCCCCCEEE
RCQIHGVAAHSSLTNQGCNAIEHAASFISYLRGMANEFKKYGNRDFSYDVPYTTLTTNLI
EEEEEEEEHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHH
KGGNAYNTIPNLCEFVFEFRNLSTDSSEDLNQKIMSYVKEELAPSLHQDHPDSNVNLDTI
CCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCHHHHCCCCCCCCCHHHH
AKAPGLDMPITDPFVRAAQTVCQSDKLMKVAYATEAGLFQQAEIPTIVCGPGSIEQAHRA
CCCCCCCCCCCCHHHHHHHHHHCCCCCEEEEHHHHCCCCCCCCCCEEEECCCCHHHHHHH
NEYVEVEQLRLCEEFIINMLRSHF
HHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11248100 [H]