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The map label for this gene is 52841206

Identifier: 52841206

GI number: 52841206

Start: 1065913

End: 1067058

Strand: Direct

Name: 52841206

Synonym: lpg0971

Alternate gene names: NA

Gene position: 1065913-1067058 (Clockwise)

Preceding gene: 52841204

Following gene: 52841207

Centisome position: 31.37

GC content: 39.97

Gene sequence:

>1146_bases
ATGTTGCGATGGATCGTGTTAATTTGTATCTCTTTGTTTTTGCCTTTATCTGCTTATGCGGACAAATCCGATTGTATCAA
TCATCATTGCATTGCGGTAATTGATGCTGGAAGTTCCAGTTCACGATTACATATTTATGCCTATGATTTGGATGAAACAA
ACACACCCATTGCAATTAGAGAGATTTGGAACCGAAAAGCCGTTCCCGGATTGCCTACAATTGAGCATGAAAACAAATCG
GTTTCAGCCTACATGGAGAAGCTATTTTCAGATGCTCCAGCTGTTTTAATGCCAGTTTATTTTTACTCCACAGCAGGCAT
GAGATTGTTGCCTAAAACTCACCACAGAAACGTCAATCAATTGGTAGCTGAGTGGTTTGACAGGCAGTATTACTGGCGAC
TTGTAACTGCAAGAACGATTTCTGGTACAGAGGAGGGTATTTTTGCCTGGCTCGCAACCAATTATCAATTAAACCTGTTT
CAACAAGAACCCCAAACTTTAGCTGGTGTGATGGATATTGGCGGAGCATCTGTTCAGATTGTTATTCCTGTTGTAAATCC
ATCTTTTATGGATCATGAGCATACAACCACAATTCGCCTCTACGGCAAGGAATTTACGGTTTTCTCTCATAGTTTTCTTG
GTCTTGGTCAGAATGAGATGGGGCATCAGTTTTTTGATTTAAAATTCTGCTTTCCAGAGGAATACGAACTGCCAAGCGGG
CGCCAAGCTCGAGGCGATGCCTATGCTTGCAAAGATGAAATTGCCATTTTAGTCAATAGCGTTCATTCTGTGAGCCGAAA
GATTAAATCGGTTTTAGCCGCTAACCCTATTGAGAAATGGTATATTTTGGGCGGCATTACCTTTATGCTGAATGACAAAC
TGTTTTCTCTGGACAATCAATATTTTACCAATCGTGATCTTATTTCCTATGCAGATCAAAATATTTGCCATCAAAAATGG
TCAACTCTTGAAGTGCTCTATCCTGATAACCTCATGGTGTTCAACTACTGCATGTTACCTTCCTACCTTTATGCTTTGTT
AGTTCACGGCTATGGACTTAAGAGTTACCAGAAAGTTAATTTCATGCCAAATAGCAAGAATATCGATTGGACCTTAGGAG
TGGTATTGCAACATAAGCAATCTTAA

Upstream 100 bases:

>100_bases
AGGTGTCTCGCTTTTATTCGCAAATTCAGTTCCTGTTTTGACCAAAAAAAACAATTAATGTAGGATAAATGCGTTATTTG
AGGTGAATTAAGGAAAGACT

Downstream 100 bases:

>100_bases
GTATACTTTTCTTTATGCCGTTGTAGCTCAGTTGGTAGAGCAATTGATTCGTAATCAAGAGGTCGGAGGTTCGACTCCTC
TCAGCGGCATAGTAAAATCA

Product: ecto-ATP diphosphohydrolase II

Products: AMP; phosphate

Alternate protein names: Ectonucleoside Triphosphate Diphosphohydrolase I

Number of amino acids: Translated: 381; Mature: 381

Protein sequence:

>381_residues
MLRWIVLICISLFLPLSAYADKSDCINHHCIAVIDAGSSSSRLHIYAYDLDETNTPIAIREIWNRKAVPGLPTIEHENKS
VSAYMEKLFSDAPAVLMPVYFYSTAGMRLLPKTHHRNVNQLVAEWFDRQYYWRLVTARTISGTEEGIFAWLATNYQLNLF
QQEPQTLAGVMDIGGASVQIVIPVVNPSFMDHEHTTTIRLYGKEFTVFSHSFLGLGQNEMGHQFFDLKFCFPEEYELPSG
RQARGDAYACKDEIAILVNSVHSVSRKIKSVLAANPIEKWYILGGITFMLNDKLFSLDNQYFTNRDLISYADQNICHQKW
STLEVLYPDNLMVFNYCMLPSYLYALLVHGYGLKSYQKVNFMPNSKNIDWTLGVVLQHKQS

Sequences:

>Translated_381_residues
MLRWIVLICISLFLPLSAYADKSDCINHHCIAVIDAGSSSSRLHIYAYDLDETNTPIAIREIWNRKAVPGLPTIEHENKS
VSAYMEKLFSDAPAVLMPVYFYSTAGMRLLPKTHHRNVNQLVAEWFDRQYYWRLVTARTISGTEEGIFAWLATNYQLNLF
QQEPQTLAGVMDIGGASVQIVIPVVNPSFMDHEHTTTIRLYGKEFTVFSHSFLGLGQNEMGHQFFDLKFCFPEEYELPSG
RQARGDAYACKDEIAILVNSVHSVSRKIKSVLAANPIEKWYILGGITFMLNDKLFSLDNQYFTNRDLISYADQNICHQKW
STLEVLYPDNLMVFNYCMLPSYLYALLVHGYGLKSYQKVNFMPNSKNIDWTLGVVLQHKQS
>Mature_381_residues
MLRWIVLICISLFLPLSAYADKSDCINHHCIAVIDAGSSSSRLHIYAYDLDETNTPIAIREIWNRKAVPGLPTIEHENKS
VSAYMEKLFSDAPAVLMPVYFYSTAGMRLLPKTHHRNVNQLVAEWFDRQYYWRLVTARTISGTEEGIFAWLATNYQLNLF
QQEPQTLAGVMDIGGASVQIVIPVVNPSFMDHEHTTTIRLYGKEFTVFSHSFLGLGQNEMGHQFFDLKFCFPEEYELPSG
RQARGDAYACKDEIAILVNSVHSVSRKIKSVLAANPIEKWYILGGITFMLNDKLFSLDNQYFTNRDLISYADQNICHQKW
STLEVLYPDNLMVFNYCMLPSYLYALLVHGYGLKSYQKVNFMPNSKNIDWTLGVVLQHKQS

Specific function: Unknown

COG id: COG5371

COG function: function code GO; Golgi nucleoside diphosphatase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI256355124, Length=374, Percent_Identity=25.4010695187166, Blast_Score=108, Evalue=8e-24,
Organism=Homo sapiens, GI166197702, Length=410, Percent_Identity=23.4146341463415, Blast_Score=105, Evalue=9e-23,
Organism=Homo sapiens, GI45827718, Length=403, Percent_Identity=25.3101736972705, Blast_Score=102, Evalue=5e-22,
Organism=Homo sapiens, GI147905700, Length=408, Percent_Identity=24.2647058823529, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI256355121, Length=408, Percent_Identity=24.2647058823529, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI45580700, Length=408, Percent_Identity=24.2647058823529, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI110431368, Length=416, Percent_Identity=23.0769230769231, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI4557421, Length=209, Percent_Identity=31.1004784688995, Blast_Score=87, Evalue=3e-17,
Organism=Homo sapiens, GI256355127, Length=335, Percent_Identity=24.7761194029851, Blast_Score=83, Evalue=4e-16,
Organism=Homo sapiens, GI110431366, Length=211, Percent_Identity=27.9620853080569, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI166235893, Length=197, Percent_Identity=27.4111675126904, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI166235895, Length=197, Percent_Identity=27.4111675126904, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI4557427, Length=397, Percent_Identity=22.9219143576826, Blast_Score=77, Evalue=4e-14,
Organism=Homo sapiens, GI9966821, Length=441, Percent_Identity=21.9954648526077, Blast_Score=76, Evalue=5e-14,
Organism=Homo sapiens, GI256355134, Length=294, Percent_Identity=23.8095238095238, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI256355130, Length=294, Percent_Identity=23.8095238095238, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17569319, Length=423, Percent_Identity=23.4042553191489, Blast_Score=86, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI17539006, Length=208, Percent_Identity=29.8076923076923, Blast_Score=82, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI17562396, Length=280, Percent_Identity=26.4285714285714, Blast_Score=75, Evalue=5e-14,
Organism=Saccharomyces cerevisiae, GI6320793, Length=234, Percent_Identity=29.9145299145299, Blast_Score=94, Evalue=4e-20,
Organism=Drosophila melanogaster, GI17137562, Length=209, Percent_Identity=28.7081339712919, Blast_Score=89, Evalue=4e-18,
Organism=Drosophila melanogaster, GI24581283, Length=209, Percent_Identity=28.7081339712919, Blast_Score=89, Evalue=4e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 3.6.1.5

Molecular weight: Translated: 43644; Mature: 43644

Theoretical pI: Translated: 6.74; Mature: 6.74

Prosite motif: PS01238 GDA1_CD39_NTPASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLRWIVLICISLFLPLSAYADKSDCINHHCIAVIDAGSSSSRLHIYAYDLDETNTPIAIR
CHHHHHHHHHHHHHHHHHCCCHHHCCCCEEEEEEECCCCCCEEEEEEEECCCCCCCCHHH
EIWNRKAVPGLPTIEHENKSVSAYMEKLFSDAPAVLMPVYFYSTAGMRLLPKTHHRNVNQ
HHHCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHCCCCCEECCCHHCCCHHH
LVAEWFDRQYYWRLVTARTISGTEEGIFAWLATNYQLNLFQQEPQTLAGVMDIGGASVQI
HHHHHHCCCEEEEEEEEEEECCCCCCEEEEEEECEEEEEEECCCHHHHHHHHCCCCEEEE
VIPVVNPSFMDHEHTTTIRLYGKEFTVFSHSFLGLGQNEMGHQFFDLKFCFPEEYELPSG
EEEECCCCCCCCCCCEEEEEECCEEEEEECHHHCCCCCCCCCEEEEEEEECCCCCCCCCC
RQARGDAYACKDEIAILVNSVHSVSRKIKSVLAANPIEKWYILGGITFMLNDKLFSLDNQ
CCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHEEEEEEEEEEECCEEEECCCC
YFTNRDLISYADQNICHQKWSTLEVLYPDNLMVFNYCMLPSYLYALLVHGYGLKSYQKVN
CCCCCCHHHHHHHHHHHHCCCEEEEEECCCEEEEHHHHHHHHHHHHHHHCCCCCCEEEEE
FMPNSKNIDWTLGVVLQHKQS
ECCCCCCCCEEEEEEEEECCC
>Mature Secondary Structure
MLRWIVLICISLFLPLSAYADKSDCINHHCIAVIDAGSSSSRLHIYAYDLDETNTPIAIR
CHHHHHHHHHHHHHHHHHCCCHHHCCCCEEEEEEECCCCCCEEEEEEEECCCCCCCCHHH
EIWNRKAVPGLPTIEHENKSVSAYMEKLFSDAPAVLMPVYFYSTAGMRLLPKTHHRNVNQ
HHHCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHCCCCCEECCCHHCCCHHH
LVAEWFDRQYYWRLVTARTISGTEEGIFAWLATNYQLNLFQQEPQTLAGVMDIGGASVQI
HHHHHHCCCEEEEEEEEEEECCCCCCEEEEEEECEEEEEEECCCHHHHHHHHCCCCEEEE
VIPVVNPSFMDHEHTTTIRLYGKEFTVFSHSFLGLGQNEMGHQFFDLKFCFPEEYELPSG
EEEECCCCCCCCCCCEEEEEECCEEEEEECHHHCCCCCCCCCEEEEEEEECCCCCCCCCC
RQARGDAYACKDEIAILVNSVHSVSRKIKSVLAANPIEKWYILGGITFMLNDKLFSLDNQ
CCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHEEEEEEEEEEECCEEEECCCC
YFTNRDLISYADQNICHQKWSTLEVLYPDNLMVFNYCMLPSYLYALLVHGYGLKSYQKVN
CCCCCCHHHHHHHHHHHHCCCEEEEEECCCEEEEHHHHHHHHHHHHHHHCCCCCCEEEEE
FMPNSKNIDWTLGVVLQHKQS
ECCCCCCCCEEEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; H2O

Specific reaction: ATP + 2 H2O = AMP + 2 phosphate

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA