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The map label for this gene is ribF

Identifier: 52841171

GI number: 52841171

Start: 1011773

End: 1012759

Strand: Direct

Name: ribF

Synonym: lpg0936

Alternate gene names: 52841171

Gene position: 1011773-1012759 (Clockwise)

Preceding gene: 52841170

Following gene: 52841172

Centisome position: 29.78

GC content: 38.8

Gene sequence:

>987_bases
ATGAAATTGTTACGCGGTTCTACTCATTTTGCTATATTTGATAAGGGTGCAGTTGCCACTATTGGCAATTTTGATGGCGT
GCATTTAGGGCATCAGCATTTGATTAAGACCCTAAGAGCAAAGGCTGATGAAATGAACTTGCCTTTAGTTATTTTATTGT
TTGAGCCTCAGCCTAAAGAGTATTTTCACAGAGAGAAAGCACCAGCACGACTTTCTACCTTGAGAGAAAAAATAGATGTC
TTAAACTTATGTCAGGTGGATTACATCTATTGCATCAAGTTTGATGCAAGGCTGGCTCAAACTCCCGCTTTGTATTTTGC
TCAGTTTTATTTATTTGAAGCATTGAAAATACGCTACCTTCTGGTTGGCCAGGATTTTCGTTTTGGCAAAAGCAGAGAAG
GTGATGTTAATTTACTCAAAACACTAGGTGCTAATTATTCCTGTGAAGTGACAGTGCAATCTGATTTTCTTATAGAAAAT
GAAAAAATCAGTTCGACGAGAATCAGAGAAGCCTTGCAACAGGGAAATTTACGTTTCGCAGCCAAGTTGTTGGGAAGACC
ATACAGCATGTGTGGACGTGTTATCAAAGGGGATGGTCGTGGTCGTCAATGGGGGATACCGACAGCCAATTTAGGCATGC
ATCGTTTATCGATCCCTTTGCAAGGTGTATATGCTGTACAAGTCCATATTAATTCGAATGTTTTTTATGGGGTTGCAAAT
ATTGGAAAGCGGCCAACTGTAGCTGGAACCAAAAATATTTTGGAGGTCCATTTATTTGATTTTCACGGATCTCTGTATGG
TCAGCTAGTGCAGGTAATTTTCTTGCACAAACTTCGAGATGAAGTTAAATTCTCAAGTGTGGAAGCGTTAATTACGCAGA
TTAATAGTGACATCATATTGGCAAAGGCCTATTTAAAACAGAATTGGCTTGATAGTGTGATTGATTCATCGAATGATGTT
GCGAATGGAATCAATAATACCGTTTAA

Upstream 100 bases:

>100_bases
TCCGTACTACTTGGTAGTACGGATAATGCTTTATAGATTTCTCAATATCTCAGAAAACCAGTATACTATGTGTTTTTTAT
TCTGCTGATTAAAACGATTC

Downstream 100 bases:

>100_bases
TTTACCCTTAATCCGGGTATTTTTTGTAAGCTCCCTTTGGGCTGTGCAGACGAAACAGAACAAGGGCATTTAAAATTATC
AAAAACTTAATGATTTGGCA

Product: riboflavin biosynthesis RibF

Products: NA

Alternate protein names: Riboflavin kinase; Flavokinase; FMN adenylyltransferase; FAD pyrophosphorylase; FAD synthase [H]

Number of amino acids: Translated: 328; Mature: 328

Protein sequence:

>328_residues
MKLLRGSTHFAIFDKGAVATIGNFDGVHLGHQHLIKTLRAKADEMNLPLVILLFEPQPKEYFHREKAPARLSTLREKIDV
LNLCQVDYIYCIKFDARLAQTPALYFAQFYLFEALKIRYLLVGQDFRFGKSREGDVNLLKTLGANYSCEVTVQSDFLIEN
EKISSTRIREALQQGNLRFAAKLLGRPYSMCGRVIKGDGRGRQWGIPTANLGMHRLSIPLQGVYAVQVHINSNVFYGVAN
IGKRPTVAGTKNILEVHLFDFHGSLYGQLVQVIFLHKLRDEVKFSSVEALITQINSDIILAKAYLKQNWLDSVIDSSNDV
ANGINNTV

Sequences:

>Translated_328_residues
MKLLRGSTHFAIFDKGAVATIGNFDGVHLGHQHLIKTLRAKADEMNLPLVILLFEPQPKEYFHREKAPARLSTLREKIDV
LNLCQVDYIYCIKFDARLAQTPALYFAQFYLFEALKIRYLLVGQDFRFGKSREGDVNLLKTLGANYSCEVTVQSDFLIEN
EKISSTRIREALQQGNLRFAAKLLGRPYSMCGRVIKGDGRGRQWGIPTANLGMHRLSIPLQGVYAVQVHINSNVFYGVAN
IGKRPTVAGTKNILEVHLFDFHGSLYGQLVQVIFLHKLRDEVKFSSVEALITQINSDIILAKAYLKQNWLDSVIDSSNDV
ANGINNTV
>Mature_328_residues
MKLLRGSTHFAIFDKGAVATIGNFDGVHLGHQHLIKTLRAKADEMNLPLVILLFEPQPKEYFHREKAPARLSTLREKIDV
LNLCQVDYIYCIKFDARLAQTPALYFAQFYLFEALKIRYLLVGQDFRFGKSREGDVNLLKTLGANYSCEVTVQSDFLIEN
EKISSTRIREALQQGNLRFAAKLLGRPYSMCGRVIKGDGRGRQWGIPTANLGMHRLSIPLQGVYAVQVHINSNVFYGVAN
IGKRPTVAGTKNILEVHLFDFHGSLYGQLVQVIFLHKLRDEVKFSSVEALITQINSDIILAKAYLKQNWLDSVIDSSNDV
ANGINNTV

Specific function: Unknown

COG id: COG0196

COG function: function code H; FAD synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ribF family [H]

Homologues:

Organism=Homo sapiens, GI269973877, Length=134, Percent_Identity=35.0746268656716, Blast_Score=67, Evalue=2e-11,
Organism=Escherichia coli, GI1786208, Length=306, Percent_Identity=45.7516339869281, Blast_Score=270, Evalue=1e-73,
Organism=Drosophila melanogaster, GI24644927, Length=135, Percent_Identity=33.3333333333333, Blast_Score=69, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004821
- InterPro:   IPR015864
- InterPro:   IPR015865
- InterPro:   IPR002606
- InterPro:   IPR014729 [H]

Pfam domain/function: PF06574 FAD_syn; PF01687 Flavokinase [H]

EC number: =2.7.1.26; =2.7.7.2 [H]

Molecular weight: Translated: 36956; Mature: 36956

Theoretical pI: Translated: 9.63; Mature: 9.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLLRGSTHFAIFDKGAVATIGNFDGVHLGHQHLIKTLRAKADEMNLPLVILLFEPQPKE
CCCCCCCCEEEEEECCCEEEECCCCCEECCHHHHHHHHHHCCCCCCCCEEEEEECCCCHH
YFHREKAPARLSTLREKIDVLNLCQVDYIYCIKFDARLAQTPALYFAQFYLFEALKIRYL
HHHHCCCCHHHHHHHHHHHHHHHHCCCEEEEEEECCHHHCCHHHHHHHHHHHHHHHEEEE
LVGQDFRFGKSREGDVNLLKTLGANYSCEVTVQSDFLIENEKISSTRIREALQQGNLRFA
EEECCCCCCCCCCCCHHHHHHHCCCCEEEEEEECCEEEECCCCHHHHHHHHHHHCCHHHH
AKLLGRPYSMCGRVIKGDGRGRQWGIPTANLGMHRLSIPLQGVYAVQVHINSNVFYGVAN
HHHHCCCHHHCCCEEECCCCCCCCCCCCCCCCCEEEECCCCEEEEEEEEECCCEEEEECC
IGKRPTVAGTKNILEVHLFDFHGSLYGQLVQVIFLHKLRDEVKFSSVEALITQINSDIIL
CCCCCCCCCCCCEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEE
AKAYLKQNWLDSVIDSSNDVANGINNTV
HHHHHHHHHHHHHHCCCCHHHCCCCCCC
>Mature Secondary Structure
MKLLRGSTHFAIFDKGAVATIGNFDGVHLGHQHLIKTLRAKADEMNLPLVILLFEPQPKE
CCCCCCCCEEEEEECCCEEEECCCCCEECCHHHHHHHHHHCCCCCCCCEEEEEECCCCHH
YFHREKAPARLSTLREKIDVLNLCQVDYIYCIKFDARLAQTPALYFAQFYLFEALKIRYL
HHHHCCCCHHHHHHHHHHHHHHHHCCCEEEEEEECCHHHCCHHHHHHHHHHHHHHHEEEE
LVGQDFRFGKSREGDVNLLKTLGANYSCEVTVQSDFLIENEKISSTRIREALQQGNLRFA
EEECCCCCCCCCCCCHHHHHHHCCCCEEEEEEECCEEEECCCCHHHHHHHHHHHCCHHHH
AKLLGRPYSMCGRVIKGDGRGRQWGIPTANLGMHRLSIPLQGVYAVQVHINSNVFYGVAN
HHHHCCCHHHCCCEEECCCCCCCCCCCCCCCCCEEEECCCCEEEEEEEEECCCEEEEECC
IGKRPTVAGTKNILEVHLFDFHGSLYGQLVQVIFLHKLRDEVKFSSVEALITQINSDIIL
CCCCCCCCCCCCEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEE
AKAYLKQNWLDSVIDSSNDVANGINNTV
HHHHHHHHHHHHHHCCCCHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]