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The map label for this gene is xseA

Identifier: 52841062

GI number: 52841062

Start: 904094

End: 905425

Strand: Reverse

Name: xseA

Synonym: lpg0826

Alternate gene names: 52841062

Gene position: 905425-904094 (Counterclockwise)

Preceding gene: 52841068

Following gene: 52841061

Centisome position: 26.65

GC content: 40.24

Gene sequence:

>1332_bases
ATGAGTAGTCAATTGCCAATACTGACCGTGAGTCAGCTGAATAGACAAGTGAAAGGTTTTCTCGAGAATGAAATAGGCCT
TGTGCATGTCGAAGGCGAAATCTCTAACTTAAGCAAACCTTCTTCAGGACATTACTATTTCACCCTGAAAGACAGCACAG
CGCAAATTCGTTGCGCTTTTTTTAAAAATCGACATTCCAATTCTCTGCTTAGAAATTTTAATGATGGTCAACAAATTGTT
GCCACTGGCAAATTAAGTCTGTATGAAGCCCGGGGAGAATATCAGCTTATTGTCGAAGAGATAGTTAAAGCAGGAATGGG
GATTCTCTATCAACGATTTGAAGAGTTAAAAATCAAACTGGCCAGCGAAGGCTTATTCAATCCTGAGAGAAAAAAACCGC
TGCCCAGAATACCCGAAACGATTGGCATCATTACATCACCCACCGGAGCAGCTATCCAGGACATTCTCTCAACTCTGGCC
CGTCGATTCCCAATAGCCAGAATTATTATTTATCCAAGTGAAGTTCAGGGGCAAACCGCCCCTCAACAACTAGTCAAGGC
CTTAAAACTGGCTAATGCCCATAAACGATGCCAGGTTCTCATCCTGGCGCGCGGCGGTGGCAGCATTGAAGACTTGTGGG
CCTTTAATGATGAATACCTTGCTCGACAAATTGCAATCAGCGAAATTCCTGTTGTTTCCGGTATTGGTCATGAAACAGAT
TTCACAATTGCTGATTTTGTAGCAGATTATCGTGCAGAAACGCCTACTGCTGCCGCTACGGCTGTTACTCCAAACTGCAT
CGAATTATTCAATATTCTTGATACGGCTATTTATCGATTGCATGATGCCATCATCAGACTAGTTAAAGGGTTGCAATTAA
AGCTCAATCATTTGATAGATAAAATTGCCTCACCCAGGCAAACTATCTCAACATATTGGCAAACCCTGGATTATCTGGAG
AGACAGTTAATATCTGCTATGACTCAATTTATTAACTTAAATATTAATAAGGTGAATATTTTTTCAACACAATTGCAAGC
TAACAATCCCAAAACACAAATTGAACGAACTAAAACCCAACTACGACAATTAATAATGCAATTAAACCAAGAGATCCGGA
TACAAGTAAACCAATTAAAAAATCAACTATCCACTAATCTTTCCACTTTGCATGCTGTAAGCCCCTTGGCTACACTAGAT
AGAGGTTATGCTATTGTGAGTAAAAACCAAAGAATACTCTTTGCTGCCCAACAGGCACAAATTGGAGATACTATCGATGT
CCGTTTAGCAAAAGGAAGTCTTGCTTGTGAGGTTACTCAAATTAAGGATTGA

Upstream 100 bases:

>100_bases
ATAACCTTAAATGAAATAACATCTCACTACAATATAATTTTATTTCTTTAATTAGTTATTGTTGTTAACAACCTTTTGAT
TTGATGGGATTTTTACCACC

Downstream 100 bases:

>100_bases
CTAAAATCATGAAGAATCTATTACATTCACTTGCCTGTCTATTGATATTAATAAGCTCAGCAAAACTATCCTATGGTCTG
GCTCTACCAGAAAATCATTC

Product: exodeoxyribonuclease VII large subunit

Products: NA

Alternate protein names: Exodeoxyribonuclease VII large subunit; Exonuclease VII large subunit

Number of amino acids: Translated: 443; Mature: 442

Protein sequence:

>443_residues
MSSQLPILTVSQLNRQVKGFLENEIGLVHVEGEISNLSKPSSGHYYFTLKDSTAQIRCAFFKNRHSNSLLRNFNDGQQIV
ATGKLSLYEARGEYQLIVEEIVKAGMGILYQRFEELKIKLASEGLFNPERKKPLPRIPETIGIITSPTGAAIQDILSTLA
RRFPIARIIIYPSEVQGQTAPQQLVKALKLANAHKRCQVLILARGGGSIEDLWAFNDEYLARQIAISEIPVVSGIGHETD
FTIADFVADYRAETPTAAATAVTPNCIELFNILDTAIYRLHDAIIRLVKGLQLKLNHLIDKIASPRQTISTYWQTLDYLE
RQLISAMTQFINLNINKVNIFSTQLQANNPKTQIERTKTQLRQLIMQLNQEIRIQVNQLKNQLSTNLSTLHAVSPLATLD
RGYAIVSKNQRILFAAQQAQIGDTIDVRLAKGSLACEVTQIKD

Sequences:

>Translated_443_residues
MSSQLPILTVSQLNRQVKGFLENEIGLVHVEGEISNLSKPSSGHYYFTLKDSTAQIRCAFFKNRHSNSLLRNFNDGQQIV
ATGKLSLYEARGEYQLIVEEIVKAGMGILYQRFEELKIKLASEGLFNPERKKPLPRIPETIGIITSPTGAAIQDILSTLA
RRFPIARIIIYPSEVQGQTAPQQLVKALKLANAHKRCQVLILARGGGSIEDLWAFNDEYLARQIAISEIPVVSGIGHETD
FTIADFVADYRAETPTAAATAVTPNCIELFNILDTAIYRLHDAIIRLVKGLQLKLNHLIDKIASPRQTISTYWQTLDYLE
RQLISAMTQFINLNINKVNIFSTQLQANNPKTQIERTKTQLRQLIMQLNQEIRIQVNQLKNQLSTNLSTLHAVSPLATLD
RGYAIVSKNQRILFAAQQAQIGDTIDVRLAKGSLACEVTQIKD
>Mature_442_residues
SSQLPILTVSQLNRQVKGFLENEIGLVHVEGEISNLSKPSSGHYYFTLKDSTAQIRCAFFKNRHSNSLLRNFNDGQQIVA
TGKLSLYEARGEYQLIVEEIVKAGMGILYQRFEELKIKLASEGLFNPERKKPLPRIPETIGIITSPTGAAIQDILSTLAR
RFPIARIIIYPSEVQGQTAPQQLVKALKLANAHKRCQVLILARGGGSIEDLWAFNDEYLARQIAISEIPVVSGIGHETDF
TIADFVADYRAETPTAAATAVTPNCIELFNILDTAIYRLHDAIIRLVKGLQLKLNHLIDKIASPRQTISTYWQTLDYLER
QLISAMTQFINLNINKVNIFSTQLQANNPKTQIERTKTQLRQLIMQLNQEIRIQVNQLKNQLSTNLSTLHAVSPLATLDR
GYAIVSKNQRILFAAQQAQIGDTIDVRLAKGSLACEVTQIKD

Specific function: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides

COG id: COG1570

COG function: function code L; Exonuclease VII, large subunit

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xseA family

Homologues:

Organism=Escherichia coli, GI1788856, Length=446, Percent_Identity=42.3766816143498, Blast_Score=356, Evalue=1e-99,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): EX7L_LEGPA (Q5X6S7)

Other databases:

- EMBL:   CR628336
- RefSeq:   YP_123216.1
- STRING:   Q5X6S7
- GeneID:   3117632
- GenomeReviews:   CR628336_GR
- KEGG:   lpp:lpp0888
- LegioList:   lpp0888
- eggNOG:   COG1570
- HOGENOM:   HBG634411
- OMA:   ANERREC
- ProtClustDB:   PRK00286
- BioCyc:   LPNE297246:LPP0888-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00378
- InterPro:   IPR003753
- InterPro:   IPR020579
- InterPro:   IPR004365
- TIGRFAMs:   TIGR00237

Pfam domain/function: PF02601 Exonuc_VII_L; PF01336 tRNA_anti

EC number: =3.1.11.6

Molecular weight: Translated: 49572; Mature: 49441

Theoretical pI: Translated: 9.49; Mature: 9.49

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSQLPILTVSQLNRQVKGFLENEIGLVHVEGEISNLSKPSSGHYYFTLKDSTAQIRCAF
CCCCCCEEEHHHHHHHHHHHHCCCCEEEEEECCHHCCCCCCCCEEEEEEECCCCEEEEEE
FKNRHSNSLLRNFNDGQQIVATGKLSLYEARGEYQLIVEEIVKAGMGILYQRFEELKIKL
HHCCCCCHHHHCCCCCCEEEEECCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
ASEGLFNPERKKPLPRIPETIGIITSPTGAAIQDILSTLARRFPIARIIIYPSEVQGQTA
HCCCCCCCHHCCCCCCCCHHHCEEECCCCHHHHHHHHHHHHHCCEEEEEEECCCCCCCCC
PQQLVKALKLANAHKRCQVLILARGGGSIEDLWAFNDEYLARQIAISEIPVVSGIGHETD
HHHHHHHHHHHCCCCCEEEEEEECCCCCHHHHHCCCHHHHHHHHHHHHCCEECCCCCCCC
FTIADFVADYRAETPTAAATAVTPNCIELFNILDTAIYRLHDAIIRLVKGLQLKLNHLID
CHHHHHHHHHCCCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KIASPRQTISTYWQTLDYLERQLISAMTQFINLNINKVNIFSTQLQANNPKTQIERTKTQ
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEEEECCCCHHHHHHHHHH
LRQLIMQLNQEIRIQVNQLKNQLSTNLSTLHAVSPLATLDRGYAIVSKNQRILFAAQQAQ
HHHHHHHHCHHHHHHHHHHHHHHHHCHHHHHHHCHHHHHCCCEEEEECCCEEEEEECCCC
IGDTIDVRLAKGSLACEVTQIKD
CCCCEEEEEECCCEEEEEEECCC
>Mature Secondary Structure 
SSQLPILTVSQLNRQVKGFLENEIGLVHVEGEISNLSKPSSGHYYFTLKDSTAQIRCAF
CCCCCEEEHHHHHHHHHHHHCCCCEEEEEECCHHCCCCCCCCEEEEEEECCCCEEEEEE
FKNRHSNSLLRNFNDGQQIVATGKLSLYEARGEYQLIVEEIVKAGMGILYQRFEELKIKL
HHCCCCCHHHHCCCCCCEEEEECCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
ASEGLFNPERKKPLPRIPETIGIITSPTGAAIQDILSTLARRFPIARIIIYPSEVQGQTA
HCCCCCCCHHCCCCCCCCHHHCEEECCCCHHHHHHHHHHHHHCCEEEEEEECCCCCCCCC
PQQLVKALKLANAHKRCQVLILARGGGSIEDLWAFNDEYLARQIAISEIPVVSGIGHETD
HHHHHHHHHHHCCCCCEEEEEEECCCCCHHHHHCCCHHHHHHHHHHHHCCEECCCCCCCC
FTIADFVADYRAETPTAAATAVTPNCIELFNILDTAIYRLHDAIIRLVKGLQLKLNHLID
CHHHHHHHHHCCCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KIASPRQTISTYWQTLDYLERQLISAMTQFINLNINKVNIFSTQLQANNPKTQIERTKTQ
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEEEECCCCHHHHHHHHHH
LRQLIMQLNQEIRIQVNQLKNQLSTNLSTLHAVSPLATLDRGYAIVSKNQRILFAAQQAQ
HHHHHHHHCHHHHHHHHHHHHHHHHCHHHHHHHCHHHHHCCCEEEEECCCEEEEEECCCC
IGDTIDVRLAKGSLACEVTQIKD
CCCCEEEEEECCCEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA