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The map label for this gene is mreB

Identifier: 52841047

GI number: 52841047

Start: 889884

End: 890927

Strand: Direct

Name: mreB

Synonym: lpg0811

Alternate gene names: 52841047

Gene position: 889884-890927 (Clockwise)

Preceding gene: 52841046

Following gene: 52841048

Centisome position: 26.19

GC content: 45.11

Gene sequence:

>1044_bases
CTGCGTATGTTCAGGAAATTAAGAGGCGTGTTTTCTAGCGATTTGTCAATCGATTTGGGAACAGCTAATACATTGATTTA
CGTAAGAGATAAGGGGATTGTTCTCAATGAACCTTCTGTAGTGGCATTGCGTAATGAATCAGGCCAGAAGCGTGTCGCCG
CTGTAGGTCTTGAAGCCAAACGCATGTTGGGAAGAACCCCTGGCAATATTAATGCGATAAGACCCATGAAAGATGGGGTT
ATTGCTGACTTTTTTGTCACCGAGAAAATGTTGCAGCACTTTATACACAAAGTGCATGAAAATAAATTTTTACGACCCAG
TCCACGAGTTTTGGTCTGTGTTCCTTGTGGTTCTACACAAGTGGAACGCAGAGCAATTCGTGAATCTGCAATGGGCGCTG
GTGCTCGAGAAGTTTTCCTTATTGAGGAGCCTATGGCTGCGGCATTAGGTTCCGGAATGCCTGTTGAGGAAGCCAGTGGT
TCTATGGTGGTTGATATAGGCGGTGGTACCACAGAAGTCGCAATTATTTCACTAAGTGGAATAGTTTATCATCAATCAGT
ACGTATTGGTGGCGATAAATTTGATGACGCAATCGTATCCTACGTACGCCGTAATTATGGTACTCTCATCGGAGAAACAA
CCGCTGAACGCATTAAACATGAAATTGGTTCGGCTTTCCCAAGCCGGGATTTATTTGAGATCGAGGTACGAGGTAGAAAT
CTTGCGGAAGGTGTACCACGTAGCTTTACTTTAACAAGCGCTGAAATCCTGGAAGCACTACAGGAACCTCTATCGGGGAT
AGTTGGTGCGGTTCGAGCTGCTTTGGAGCTTGCTCCGCCTGAGTTGGCTGCAGATATTGCTGAAAGAGGTATGGTTTTAA
CAGGCGGAGGCGCTCTGTTGAAAAATATAGACACCTTGTTGATGGAAGAAACTGGATTACCCGTATTAATAGCTGAAGAT
CCATTAACCTGCGTTGCGCGTGGTGGTGGTAAAGCTTTAGAAACCATGGATTTGCGCGGCGGTGATTTCCTCTCAACAGA
ATAA

Upstream 100 bases:

>100_bases
TTAAAAGCAGTTGTCTGGTGTATAAAATTCTTATGCGGCAACTGTCGATTTTTATCCAAATATAGGATAAAGTAGCAATC
AAAAAAACAACGGGGTAGTA

Downstream 100 bases:

>100_bases
TAAACACAATAGATTATTTGCAAAGGGCGGACACAGTTCTCTGGGATTTGTGTTTGCCCTTGCTTTTTCTATTCTCCTGA
TGTTTTCTGATTATCATTAC

Product: rod shape-determining protein MreB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 347; Mature: 347

Protein sequence:

>347_residues
MRMFRKLRGVFSSDLSIDLGTANTLIYVRDKGIVLNEPSVVALRNESGQKRVAAVGLEAKRMLGRTPGNINAIRPMKDGV
IADFFVTEKMLQHFIHKVHENKFLRPSPRVLVCVPCGSTQVERRAIRESAMGAGAREVFLIEEPMAAALGSGMPVEEASG
SMVVDIGGGTTEVAIISLSGIVYHQSVRIGGDKFDDAIVSYVRRNYGTLIGETTAERIKHEIGSAFPSRDLFEIEVRGRN
LAEGVPRSFTLTSAEILEALQEPLSGIVGAVRAALELAPPELAADIAERGMVLTGGGALLKNIDTLLMEETGLPVLIAED
PLTCVARGGGKALETMDLRGGDFLSTE

Sequences:

>Translated_347_residues
MRMFRKLRGVFSSDLSIDLGTANTLIYVRDKGIVLNEPSVVALRNESGQKRVAAVGLEAKRMLGRTPGNINAIRPMKDGV
IADFFVTEKMLQHFIHKVHENKFLRPSPRVLVCVPCGSTQVERRAIRESAMGAGAREVFLIEEPMAAALGSGMPVEEASG
SMVVDIGGGTTEVAIISLSGIVYHQSVRIGGDKFDDAIVSYVRRNYGTLIGETTAERIKHEIGSAFPSRDLFEIEVRGRN
LAEGVPRSFTLTSAEILEALQEPLSGIVGAVRAALELAPPELAADIAERGMVLTGGGALLKNIDTLLMEETGLPVLIAED
PLTCVARGGGKALETMDLRGGDFLSTE
>Mature_347_residues
MRMFRKLRGVFSSDLSIDLGTANTLIYVRDKGIVLNEPSVVALRNESGQKRVAAVGLEAKRMLGRTPGNINAIRPMKDGV
IADFFVTEKMLQHFIHKVHENKFLRPSPRVLVCVPCGSTQVERRAIRESAMGAGAREVFLIEEPMAAALGSGMPVEEASG
SMVVDIGGGTTEVAIISLSGIVYHQSVRIGGDKFDDAIVSYVRRNYGTLIGETTAERIKHEIGSAFPSRDLFEIEVRGRN
LAEGVPRSFTLTSAEILEALQEPLSGIVGAVRAALELAPPELAADIAERGMVLTGGGALLKNIDTLLMEETGLPVLIAED
PLTCVARGGGKALETMDLRGGDFLSTE

Specific function: Involved in formation of the rod shape of the cell. May act as a negative regulator of ftsI [H]

COG id: COG1077

COG function: function code D; Actin-like ATPase involved in cell morphogenesis

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsA/mreB family [H]

Homologues:

Organism=Escherichia coli, GI87082236, Length=347, Percent_Identity=78.3861671469741, Blast_Score=555, Evalue=1e-159,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001023
- InterPro:   IPR004753 [H]

Pfam domain/function: PF06723 MreB_Mbl [H]

EC number: NA

Molecular weight: Translated: 37242; Mature: 37242

Theoretical pI: Translated: 5.51; Mature: 5.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRMFRKLRGVFSSDLSIDLGTANTLIYVRDKGIVLNEPSVVALRNESGQKRVAAVGLEAK
CCHHHHHHHHHCCCCEEEECCCCEEEEEECCCEEECCCCEEEEECCCCCCEEEECCHHHH
RMLGRTPGNINAIRPMKDGVIADFFVTEKMLQHFIHKVHENKFLRPSPRVLVCVPCGSTQ
HHHCCCCCCCCEECCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCHH
VERRAIRESAMGAGAREVFLIEEPMAAALGSGMPVEEASGSMVVDIGGGTTEVAIISLSG
HHHHHHHHHHCCCCCEEEEEECCCHHHHHCCCCCCCCCCCCEEEEECCCCEEEEEEEEEC
IVYHQSVRIGGDKFDDAIVSYVRRNYGTLIGETTAERIKHEIGSAFPSRDLFEIEVRGRN
EEEEEEEEECCCHHHHHHHHHHHHHHCHHHCHHHHHHHHHHHHCCCCCCCEEEEEECCCH
LAEGVPRSFTLTSAEILEALQEPLSGIVGAVRAALELAPPELAADIAERGMVLTGGGALL
HHCCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCEEEECCCHHH
KNIDTLLMEETGLPVLIAEDPLTCVARGGGKALETMDLRGGDFLSTE
HHHHHHHHHCCCCEEEEECCCCEEEECCCCCEEEEEECCCCCCCCCC
>Mature Secondary Structure
MRMFRKLRGVFSSDLSIDLGTANTLIYVRDKGIVLNEPSVVALRNESGQKRVAAVGLEAK
CCHHHHHHHHHCCCCEEEECCCCEEEEEECCCEEECCCCEEEEECCCCCCEEEECCHHHH
RMLGRTPGNINAIRPMKDGVIADFFVTEKMLQHFIHKVHENKFLRPSPRVLVCVPCGSTQ
HHHCCCCCCCCEECCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCHH
VERRAIRESAMGAGAREVFLIEEPMAAALGSGMPVEEASGSMVVDIGGGTTEVAIISLSG
HHHHHHHHHHCCCCCEEEEEECCCHHHHHCCCCCCCCCCCCEEEEECCCCEEEEEEEEEC
IVYHQSVRIGGDKFDDAIVSYVRRNYGTLIGETTAERIKHEIGSAFPSRDLFEIEVRGRN
EEEEEEEEECCCHHHHHHHHHHHHHHCHHHCHHHHHHHHHHHHCCCCCCCEEEEEECCCH
LAEGVPRSFTLTSAEILEALQEPLSGIVGAVRAALELAPPELAADIAERGMVLTGGGALL
HHCCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCEEEECCCHHH
KNIDTLLMEETGLPVLIAEDPLTCVARGGGKALETMDLRGGDFLSTE
HHHHHHHHHCCCCEEEEECCCCEEEECCCCCEEEEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]