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The map label for this gene is comM

Identifier: 52840827

GI number: 52840827

Start: 623078

End: 624589

Strand: Reverse

Name: comM

Synonym: lpg0590

Alternate gene names: 52840827

Gene position: 624589-623078 (Counterclockwise)

Preceding gene: 52840828

Following gene: 52840826

Centisome position: 18.38

GC content: 41.47

Gene sequence:

>1512_bases
ATGAATCTCGCATTTACCAAAACGCGAAGCACTATTGGTATTGTCGCACAACCAGTATCTGTGGAAGTCCATTTATCAAA
TGGATTACCAGGTTTTACTATGGTAGGACTTGCTGAAACAGCAGTGAAAGAAAGTAAAGACCGAGTGCGCAGCGCTATTA
TAAATAGCCAATTCGAATTTCCATGCCGTAAAATTACCGTTAATCTTGGCCCTGCCAATTTACCTAAAACGGGAAGTGGC
TTTGACTTGCCTATTGCACTAGGGATACTCGCAGCATCGGAACAAATTCCTCTCACCAACCTTGCAAACCACGAATTTAT
TGGAGAATTGGCTTTAAGCGGCGAGCTTAGAGGGGTTTCTGCCATTATACCTGCTGTTCTTGCCGCTCATAAAGACAATC
AACATCTGATTATAGCGAATGCAAATGCTGCCGAAGCTTCTTTAACCGGCCATCCAAAAGTCTTTACTGCCAATAACTTA
CGCGAAGTTTGTGATTATCTATGCCAGGGTACTTCTTTACAGAACTTACCTCCCAAACCAGATCTTTTATTAAATAACCA
TGAATTGGATTGGTCTGATATTAAGGGGCAACATCATGCCAAAAATGCTATGGTCATTGCTGCCTGTGGGGGACACAGTA
TTCTCCTAAGTGGCGCACCAGGCAGTGGAAAAACGATGATGGCAAAAAGATTTAGTACCTTGCTACCTGAACTATCCGAA
ACACAAGCTCTCGAATGCGCAGCCATTAATTCAATTCGAGGCAAATTACCTGATTTCAGGGAATGGCGTTTGCCTCCTTT
TCGTGCACCACATCATACTGCTTCACCTGTCGCTTTAGTCGGAGGAGGCAACCCGCCGAAACCCGGTGAAATTTCATTAG
CCCATCACGGCGTATTATTTTTAGATGAATTACCTGAATTTAATCGGCAAGTATTAGAGACACTTAGAGAACCTTTGGAG
TCAGGGCATATTTGCATTTCCAGGGCAGCTGCACAAATAGAGTTTCCTGCCAAATTTCAATTAATTGCAGCAATGAATCC
TTGCCCTTGTGGCCAATGGGGTAATTCACAAGCCAATTGCTTATGTACTCCTGATAGAATCAGCCGCTATTTGGCAAAAC
TTTCTGCTCCATTATTAGATAGAATCGATATGCAGGTTACAATTCACGCATTATCTCAAGAGGAGTTAATTAAACCCAAT
ACCCATTTAGAAAAACAAAGTCCTGCTATTAGAGAAAAGGTAACAAAGATGCATGAAATACAAATGGCACGACAAGATAG
TCTCAATGCCAATTTAAATTCCAAAACATGCGAAATGGTTTGCGAATTGGGATCAGAAGAACAATTGTTTCTCCGAGAGG
TGATGAGTAAACTGAAACTGTCTGCTCGTGGTTACCATCGCTTACTAAAAGTAAGCAGGACAATTGCTGATATGAGTGAA
TGTAATAAGGTCATGCTAAACCATCTGCAACAGGCGTTATCCTATAAACAAATCTTGCATTTGCCTAAATAA

Upstream 100 bases:

>100_bases
TTCATTAAACGGCAAGAAGTTAAAAATAATAAATAATAACTATTAGTCGTCCATAGGAAATGGGATCGACTTAAGTCCAA
CATAATAAGGAAAAAATCTT

Downstream 100 bases:

>100_bases
AATTTCTTCTCAAGTATTGGGGTGTATAAAAAATCAATTCCGTATTAATCATATATACCTAAGTTGTCCTATAATTATAC
ATAAATATAAATTACGGGGC

Product: competence related protein ComM

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 503; Mature: 503

Protein sequence:

>503_residues
MNLAFTKTRSTIGIVAQPVSVEVHLSNGLPGFTMVGLAETAVKESKDRVRSAIINSQFEFPCRKITVNLGPANLPKTGSG
FDLPIALGILAASEQIPLTNLANHEFIGELALSGELRGVSAIIPAVLAAHKDNQHLIIANANAAEASLTGHPKVFTANNL
REVCDYLCQGTSLQNLPPKPDLLLNNHELDWSDIKGQHHAKNAMVIAACGGHSILLSGAPGSGKTMMAKRFSTLLPELSE
TQALECAAINSIRGKLPDFREWRLPPFRAPHHTASPVALVGGGNPPKPGEISLAHHGVLFLDELPEFNRQVLETLREPLE
SGHICISRAAAQIEFPAKFQLIAAMNPCPCGQWGNSQANCLCTPDRISRYLAKLSAPLLDRIDMQVTIHALSQEELIKPN
THLEKQSPAIREKVTKMHEIQMARQDSLNANLNSKTCEMVCELGSEEQLFLREVMSKLKLSARGYHRLLKVSRTIADMSE
CNKVMLNHLQQALSYKQILHLPK

Sequences:

>Translated_503_residues
MNLAFTKTRSTIGIVAQPVSVEVHLSNGLPGFTMVGLAETAVKESKDRVRSAIINSQFEFPCRKITVNLGPANLPKTGSG
FDLPIALGILAASEQIPLTNLANHEFIGELALSGELRGVSAIIPAVLAAHKDNQHLIIANANAAEASLTGHPKVFTANNL
REVCDYLCQGTSLQNLPPKPDLLLNNHELDWSDIKGQHHAKNAMVIAACGGHSILLSGAPGSGKTMMAKRFSTLLPELSE
TQALECAAINSIRGKLPDFREWRLPPFRAPHHTASPVALVGGGNPPKPGEISLAHHGVLFLDELPEFNRQVLETLREPLE
SGHICISRAAAQIEFPAKFQLIAAMNPCPCGQWGNSQANCLCTPDRISRYLAKLSAPLLDRIDMQVTIHALSQEELIKPN
THLEKQSPAIREKVTKMHEIQMARQDSLNANLNSKTCEMVCELGSEEQLFLREVMSKLKLSARGYHRLLKVSRTIADMSE
CNKVMLNHLQQALSYKQILHLPK
>Mature_503_residues
MNLAFTKTRSTIGIVAQPVSVEVHLSNGLPGFTMVGLAETAVKESKDRVRSAIINSQFEFPCRKITVNLGPANLPKTGSG
FDLPIALGILAASEQIPLTNLANHEFIGELALSGELRGVSAIIPAVLAAHKDNQHLIIANANAAEASLTGHPKVFTANNL
REVCDYLCQGTSLQNLPPKPDLLLNNHELDWSDIKGQHHAKNAMVIAACGGHSILLSGAPGSGKTMMAKRFSTLLPELSE
TQALECAAINSIRGKLPDFREWRLPPFRAPHHTASPVALVGGGNPPKPGEISLAHHGVLFLDELPEFNRQVLETLREPLE
SGHICISRAAAQIEFPAKFQLIAAMNPCPCGQWGNSQANCLCTPDRISRYLAKLSAPLLDRIDMQVTIHALSQEELIKPN
THLEKQSPAIREKVTKMHEIQMARQDSLNANLNSKTCEMVCELGSEEQLFLREVMSKLKLSARGYHRLLKVSRTIADMSE
CNKVMLNHLQQALSYKQILHLPK

Specific function: Induced during competence development. Not needed for DNA uptake. May be involved in a recombination step [H]

COG id: COG0606

COG function: function code O; Predicted ATPase with chaperone activity

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily [H]

Homologues:

Organism=Escherichia coli, GI145693202, Length=508, Percent_Identity=47.244094488189, Blast_Score=458, Evalue=1e-130,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR001208
- InterPro:   IPR004482
- InterPro:   IPR000523
- InterPro:   IPR020568 [H]

Pfam domain/function: PF01078 Mg_chelatase [H]

EC number: NA

Molecular weight: Translated: 54928; Mature: 54928

Theoretical pI: Translated: 8.03; Mature: 8.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLAFTKTRSTIGIVAQPVSVEVHLSNGLPGFTMVGLAETAVKESKDRVRSAIINSQFEF
CCCEEECCCCCEEEEECCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
PCRKITVNLGPANLPKTGSGFDLPIALGILAASEQIPLTNLANHEFIGELALSGELRGVS
CEEEEEEEECCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCCCCHHH
AIIPAVLAAHKDNQHLIIANANAAEASLTGHPKVFTANNLREVCDYLCQGTSLQNLPPKP
HHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCEEECCCHHHHHHHHHCCCCCCCCCCCC
DLLLNNHELDWSDIKGQHHAKNAMVIAACGGHSILLSGAPGSGKTMMAKRFSTLLPELSE
CEEECCCCCCHHHCCCCCCCCCEEEEEEECCCEEEEECCCCCCCHHHHHHHHHHCCCCHH
TQALECAAINSIRGKLPDFREWRLPPFRAPHHTASPVALVGGGNPPKPGEISLAHHGVLF
HHHHHHHHHHHHHCCCCCCHHCCCCCCCCCCCCCCCEEEEECCCCCCCCEEEEECCCEEE
LDELPEFNRQVLETLREPLESGHICISRAAAQIEFPAKFQLIAAMNPCPCGQWGNSQANC
EHHCCHHHHHHHHHHHHHHHCCCEEEEEHHHEEECCCCEEEEEECCCCCCCCCCCCCCCE
LCTPDRISRYLAKLSAPLLDRIDMQVTIHALSQEELIKPNTHLEKQSPAIREKVTKMHEI
EECHHHHHHHHHHHCCHHHHHCCCEEEEEECCHHHHCCCCCCCCCCCCHHHHHHHHHHHH
QMARQDSLNANLNSKTCEMVCELGSEEQLFLREVMSKLKLSARGYHRLLKVSRTIADMSE
HHHHHHCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
CNKVMLNHLQQALSYKQILHLPK
HHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MNLAFTKTRSTIGIVAQPVSVEVHLSNGLPGFTMVGLAETAVKESKDRVRSAIINSQFEF
CCCEEECCCCCEEEEECCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
PCRKITVNLGPANLPKTGSGFDLPIALGILAASEQIPLTNLANHEFIGELALSGELRGVS
CEEEEEEEECCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCCCCHHH
AIIPAVLAAHKDNQHLIIANANAAEASLTGHPKVFTANNLREVCDYLCQGTSLQNLPPKP
HHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCEEECCCHHHHHHHHHCCCCCCCCCCCC
DLLLNNHELDWSDIKGQHHAKNAMVIAACGGHSILLSGAPGSGKTMMAKRFSTLLPELSE
CEEECCCCCCHHHCCCCCCCCCEEEEEEECCCEEEEECCCCCCCHHHHHHHHHHCCCCHH
TQALECAAINSIRGKLPDFREWRLPPFRAPHHTASPVALVGGGNPPKPGEISLAHHGVLF
HHHHHHHHHHHHHCCCCCCHHCCCCCCCCCCCCCCCEEEEECCCCCCCCEEEEECCCEEE
LDELPEFNRQVLETLREPLESGHICISRAAAQIEFPAKFQLIAAMNPCPCGQWGNSQANC
EHHCCHHHHHHHHHHHHHHHCCCEEEEEHHHEEECCCCEEEEEECCCCCCCCCCCCCCCE
LCTPDRISRYLAKLSAPLLDRIDMQVTIHALSQEELIKPNTHLEKQSPAIREKVTKMHEI
EECHHHHHHHHHHHCCHHHHHCCCEEEEEECCHHHHCCCCCCCCCCCCHHHHHHHHHHHH
QMARQDSLNANLNSKTCEMVCELGSEEQLFLREVMSKLKLSARGYHRLLKVSRTIADMSE
HHHHHHCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
CNKVMLNHLQQALSYKQILHLPK
HHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800; 9457884 [H]