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The map label for this gene is plsC

Identifier: 52840794

GI number: 52840794

Start: 592083

End: 592856

Strand: Reverse

Name: plsC

Synonym: lpg0551

Alternate gene names: 52840794

Gene position: 592856-592083 (Counterclockwise)

Preceding gene: 52840795

Following gene: 52840793

Centisome position: 17.45

GC content: 39.28

Gene sequence:

>774_bases
TTGTTGTATGATGGCCCTCTCATAATCCCATGCGCTCTAACGATGAAAATAAGTCGATTAAAAACTTTTTGGATAATTAC
CCGCCTATTTTATTACACAGGTGTTGCTTGCACTCGCTCCATATTTAAGTATCTTTTTAGCACCCCTACGAGGCCATGGG
TTGATAAAGTCATCCACCATTGGGTTGATCAACTCTTAAATGCTGTGAAAGTAGAATATAAAGTAATCAATCCACATAAT
GTCCAGCCTCAGCCTGGCAAGGCAACGATCCTTATGTGCAATCATTCCAGTGCTTATGATATTCCTTTAGGCTTCAAAGC
ATTCCCTAATAACTCTATTCGCATGCTTGCCAAACGAGAACTCTCCAAAATTCCACTTTTAGGGAAGGGAATGGCTGCAG
CAGAATTCCCTTTTATTGACAGAAAAAACAGATTTCAAGCCATAAAGGATTTGGAATTTGCCCAGCAACTGATGGAGAGT
GGCATTATTCTATGGATTGCACCAGAAGGAACTCGCTCAAAAGATGGCAAACTAGCCCCATTTAAAAAAGGTGGTTTTAT
CACTGCTATTCAAGCCAAGGCTACTATAATTCCCATAGGAATTCGCGGAGCTTTTGATATTCTCCCTGCCCGCACCTTTA
ATATACATTTGAATCAAAAAGCAGAAATTCATATTGGCGAGCCTATTGATGCAGCTCAATATTCAATTGAAAATAAAGAG
GAATTAATCGAAAAAACCCATCAATCAATAAAAAAGCTGGTTGGGGAGAATTGA

Upstream 100 bases:

>100_bases
ATCTATCTGTCTTCCGATTGCTATACCTTGTATTAATGCTGATATCTATCTTTGGTTTAAAATACACGGCTTGATTTGAA
TCGTTCCAGTATTCCTCAAC

Downstream 100 bases:

>100_bases
AAAAACTCACATCCCGGTTTGCTGAAAAAGATGACTAAAAATACCTACAATAACTAATAAAAAAAAGACCACGTTATACA
AAAAATAAAATTGATTCCTA

Product: 1-acyl-sn-glycerol-3-phosphate acetyltransferase

Products: NA

Alternate protein names: 1-AGP acyltransferase; 1-AGPAT; Lysophosphatidic acid acyltransferase; LPAAT [H]

Number of amino acids: Translated: 257; Mature: 257

Protein sequence:

>257_residues
MLYDGPLIIPCALTMKISRLKTFWIITRLFYYTGVACTRSIFKYLFSTPTRPWVDKVIHHWVDQLLNAVKVEYKVINPHN
VQPQPGKATILMCNHSSAYDIPLGFKAFPNNSIRMLAKRELSKIPLLGKGMAAAEFPFIDRKNRFQAIKDLEFAQQLMES
GIILWIAPEGTRSKDGKLAPFKKGGFITAIQAKATIIPIGIRGAFDILPARTFNIHLNQKAEIHIGEPIDAAQYSIENKE
ELIEKTHQSIKKLVGEN

Sequences:

>Translated_257_residues
MLYDGPLIIPCALTMKISRLKTFWIITRLFYYTGVACTRSIFKYLFSTPTRPWVDKVIHHWVDQLLNAVKVEYKVINPHN
VQPQPGKATILMCNHSSAYDIPLGFKAFPNNSIRMLAKRELSKIPLLGKGMAAAEFPFIDRKNRFQAIKDLEFAQQLMES
GIILWIAPEGTRSKDGKLAPFKKGGFITAIQAKATIIPIGIRGAFDILPARTFNIHLNQKAEIHIGEPIDAAQYSIENKE
ELIEKTHQSIKKLVGEN
>Mature_257_residues
MLYDGPLIIPCALTMKISRLKTFWIITRLFYYTGVACTRSIFKYLFSTPTRPWVDKVIHHWVDQLLNAVKVEYKVINPHN
VQPQPGKATILMCNHSSAYDIPLGFKAFPNNSIRMLAKRELSKIPLLGKGMAAAEFPFIDRKNRFQAIKDLEFAQQLMES
GIILWIAPEGTRSKDGKLAPFKKGGFITAIQAKATIIPIGIRGAFDILPARTFNIHLNQKAEIHIGEPIDAAQYSIENKE
ELIEKTHQSIKKLVGEN

Specific function: Converts lysophosphatidic acid (LPA) into phosphatidic acid by incorporating acyl moiety at the 2 position [H]

COG id: COG0204

COG function: function code I; 1-acyl-sn-glycerol-3-phosphate acyltransferase

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family [H]

Homologues:

Organism=Homo sapiens, GI5453718, Length=167, Percent_Identity=26.9461077844311, Blast_Score=75, Evalue=8e-14,
Organism=Homo sapiens, GI15100175, Length=167, Percent_Identity=26.9461077844311, Blast_Score=75, Evalue=8e-14,
Organism=Homo sapiens, GI6041665, Length=182, Percent_Identity=24.1758241758242, Blast_Score=74, Evalue=2e-13,
Organism=Escherichia coli, GI1789395, Length=240, Percent_Identity=27.5, Blast_Score=65, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17564032, Length=127, Percent_Identity=35.4330708661417, Blast_Score=85, Evalue=5e-17,
Organism=Saccharomyces cerevisiae, GI6320151, Length=201, Percent_Identity=28.3582089552239, Blast_Score=73, Evalue=4e-14,
Organism=Drosophila melanogaster, GI281364648, Length=204, Percent_Identity=29.9019607843137, Blast_Score=69, Evalue=4e-12,
Organism=Drosophila melanogaster, GI24582856, Length=204, Percent_Identity=29.9019607843137, Blast_Score=69, Evalue=4e-12,
Organism=Drosophila melanogaster, GI24582854, Length=204, Percent_Identity=29.9019607843137, Blast_Score=69, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002123
- InterPro:   IPR004552 [H]

Pfam domain/function: PF01553 Acyltransferase [H]

EC number: =2.3.1.51 [H]

Molecular weight: Translated: 29075; Mature: 29075

Theoretical pI: Translated: 10.16; Mature: 10.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLYDGPLIIPCALTMKISRLKTFWIITRLFYYTGVACTRSIFKYLFSTPTRPWVDKVIHH
CCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
WVDQLLNAVKVEYKVINPHNVQPQPGKATILMCNHSSAYDIPLGFKAFPNNSIRMLAKRE
HHHHHHHHHEEEEEEECCCCCCCCCCCEEEEEECCCCCCCCCCCCEECCCCHHHHHHHHH
LSKIPLLGKGMAAAEFPFIDRKNRFQAIKDLEFAQQLMESGIILWIAPEGTRSKDGKLAP
HHHCCCCCCCCCHHCCCCCCCCHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCCCCCCCC
FKKGGFITAIQAKATIIPIGIRGAFDILPARTFNIHLNQKAEIHIGEPIDAAQYSIENKE
CCCCCEEEEEECCEEEEEEECCCHHHCCCCEEEEEEECCCEEEEECCCCCHHHHCCCCHH
ELIEKTHQSIKKLVGEN
HHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MLYDGPLIIPCALTMKISRLKTFWIITRLFYYTGVACTRSIFKYLFSTPTRPWVDKVIHH
CCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
WVDQLLNAVKVEYKVINPHNVQPQPGKATILMCNHSSAYDIPLGFKAFPNNSIRMLAKRE
HHHHHHHHHEEEEEEECCCCCCCCCCCEEEEEECCCCCCCCCCCCEECCCCHHHHHHHHH
LSKIPLLGKGMAAAEFPFIDRKNRFQAIKDLEFAQQLMESGIILWIAPEGTRSKDGKLAP
HHHCCCCCCCCCHHCCCCCCCCHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCCCCCCCC
FKKGGFITAIQAKATIIPIGIRGAFDILPARTFNIHLNQKAEIHIGEPIDAAQYSIENKE
CCCCCEEEEEECCEEEEEEECCCHHHCCCCEEEEEEECCCEEEEECCCCCHHHHCCCCHH
ELIEKTHQSIKKLVGEN
HHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]