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The map label for this gene is corA

Identifier: 52840522

GI number: 52840522

Start: 314892

End: 315944

Strand: Reverse

Name: corA

Synonym: lpg0267

Alternate gene names: 52840522

Gene position: 315944-314892 (Counterclockwise)

Preceding gene: 52840527

Following gene: 52840520

Centisome position: 9.3

GC content: 33.52

Gene sequence:

>1053_bases
TTGTCAATATCATTTAAGTCTCCTATTCTTAAACTATATGAGGAAATTAATCGAATAAGGATGAGCATTGAAATGCATTC
GTTTGATTCAATCGCTGTTGAATTTGATTTAAAAAATCATAGTATGCAAAAAATTGCGATTGAGGATTTAAACATCGATT
ACCAGGATAAAGATAAAATTTATTGGATACATAGCGATTTAAACCAGAAAAACATCTTTAAAAAATTGCGAGAAAAATTA
CGATTACCTGAAGAAGTGATTCAATTGTGTGGAGAAAAAGACAATAGATCCACAACCATAGAGATCGATGAAGCGCTCAC
TTTGCAAATTCAAGGCTTGTGCTCAATGAAGTTGAATGACAATTATGATGCTGATTTTGGCAATTTGATTATTCATCTCA
CACCAAATTATTGCTTTACAGCTTCTAAAACACTTTCTTCAGTTTTGTTTGACCTGTTAAAAAGCTGCCCAAAATCCTTA
CCCTATGCCAAAACATCTTGTTTTTTGTTATTTTTGCTTCTGGAAGGAGTAATTAATGATTATGCCAAGATTCATTTAGC
TTATGAAGAATTGGCCGATCAATTGGACGCGCAAGCTCGTACCACCAATAAAAATACCTATTCGCAAGTTTTGGAATTAA
AACATGGTGTAATGAAAATTAAGCGTTATACCATAGCAATAAGAGAAATATTAATGCGTCTCACTAGCCGAAATATTTTA
GTCATCTCAGAGCAGTGTCGAAACTCCTTATATAATTTATCGAATCACTGCCATCTTATTGTCAATGAAATAGACTCTCT
TCGCGATATATTAAATGGCTTATTAGGACAAATCGACAATCAGTTGATGCAAAACATGAATGAGACTATGAGAGTATTAA
CTGCCTTCGCAGCCATATTCTTACCTTTAAGTTTAATTACCGGAATTTATGGGATGAATTTCTACTGGATGCCGGAATTA
GGTTGGAAATATGGCTACTTTTGGGCACTTGGATTAATCGTGCTGTGTGCTCTGCTACTGTTTTTAATTTTCAGAAAAAA
GAAGTGGTTTTAG

Upstream 100 bases:

>100_bases
AGAGTCTGAATTATATAAACAAGACGAAAGCCAAACTGGAGATTAACTCTCCACGATACACTCACAGTCTATTGGAAAAC
CCGGACTATTTAAAAATAGT

Downstream 100 bases:

>100_bases
GCTACTTCATAGAGCTAACCGACACTAAAATTTTCCCCTACTCCTTTAACTACCCGCCATAAGCATTCAGCCCCATGATA
GCTAAGCGCCTGAATATCCG

Product: hypothetical protein

Products: Ni2; [Cytoplasm]; Co; 2 [Cytoplasm]; Mg (II) [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 350; Mature: 349

Protein sequence:

>350_residues
MSISFKSPILKLYEEINRIRMSIEMHSFDSIAVEFDLKNHSMQKIAIEDLNIDYQDKDKIYWIHSDLNQKNIFKKLREKL
RLPEEVIQLCGEKDNRSTTIEIDEALTLQIQGLCSMKLNDNYDADFGNLIIHLTPNYCFTASKTLSSVLFDLLKSCPKSL
PYAKTSCFLLFLLLEGVINDYAKIHLAYEELADQLDAQARTTNKNTYSQVLELKHGVMKIKRYTIAIREILMRLTSRNIL
VISEQCRNSLYNLSNHCHLIVNEIDSLRDILNGLLGQIDNQLMQNMNETMRVLTAFAAIFLPLSLITGIYGMNFYWMPEL
GWKYGYFWALGLIVLCALLLFLIFRKKKWF

Sequences:

>Translated_350_residues
MSISFKSPILKLYEEINRIRMSIEMHSFDSIAVEFDLKNHSMQKIAIEDLNIDYQDKDKIYWIHSDLNQKNIFKKLREKL
RLPEEVIQLCGEKDNRSTTIEIDEALTLQIQGLCSMKLNDNYDADFGNLIIHLTPNYCFTASKTLSSVLFDLLKSCPKSL
PYAKTSCFLLFLLLEGVINDYAKIHLAYEELADQLDAQARTTNKNTYSQVLELKHGVMKIKRYTIAIREILMRLTSRNIL
VISEQCRNSLYNLSNHCHLIVNEIDSLRDILNGLLGQIDNQLMQNMNETMRVLTAFAAIFLPLSLITGIYGMNFYWMPEL
GWKYGYFWALGLIVLCALLLFLIFRKKKWF
>Mature_349_residues
SISFKSPILKLYEEINRIRMSIEMHSFDSIAVEFDLKNHSMQKIAIEDLNIDYQDKDKIYWIHSDLNQKNIFKKLREKLR
LPEEVIQLCGEKDNRSTTIEIDEALTLQIQGLCSMKLNDNYDADFGNLIIHLTPNYCFTASKTLSSVLFDLLKSCPKSLP
YAKTSCFLLFLLLEGVINDYAKIHLAYEELADQLDAQARTTNKNTYSQVLELKHGVMKIKRYTIAIREILMRLTSRNILV
ISEQCRNSLYNLSNHCHLIVNEIDSLRDILNGLLGQIDNQLMQNMNETMRVLTAFAAIFLPLSLITGIYGMNFYWMPELG
WKYGYFWALGLIVLCALLLFLIFRKKKWF

Specific function: Mediates influx of magnesium ions [H]

COG id: COG0598

COG function: function code P; Mg2+ and Co2+ transporters

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family [H]

Homologues:

Organism=Escherichia coli, GI2367297, Length=63, Percent_Identity=38.0952380952381, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004488
- InterPro:   IPR002523 [H]

Pfam domain/function: PF01544 CorA [H]

EC number: NA

Molecular weight: Translated: 40740; Mature: 40609

Theoretical pI: Translated: 7.47; Mature: 7.47

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSISFKSPILKLYEEINRIRMSIEMHSFDSIAVEFDLKNHSMQKIAIEDLNIDYQDKDKI
CCCCCCCHHHHHHHHHHHHHHHHEEECCCCEEEEEEECCCCHHEEEHHHCCCCCCCCCCE
YWIHSDLNQKNIFKKLREKLRLPEEVIQLCGEKDNRSTTIEIDEALTLQIQGLCSMKLND
EEEECCCCHHHHHHHHHHHHCCHHHHHHHCCCCCCCCCEEEECCEEEEEEECEEEEEECC
NYDADFGNLIIHLTPNYCFTASKTLSSVLFDLLKSCPKSLPYAKTSCFLLFLLLEGVIND
CCCCCCCCEEEEECCCCEEHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
YAKIHLAYEELADQLDAQARTTNKNTYSQVLELKHGVMKIKRYTIAIREILMRLTSRNIL
HHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEE
VISEQCRNSLYNLSNHCHLIVNEIDSLRDILNGLLGQIDNQLMQNMNETMRVLTAFAAIF
EEHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LPLSLITGIYGMNFYWMPELGWKYGYFWALGLIVLCALLLFLIFRKKKWF
HHHHHHHHHHCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SISFKSPILKLYEEINRIRMSIEMHSFDSIAVEFDLKNHSMQKIAIEDLNIDYQDKDKI
CCCCCCHHHHHHHHHHHHHHHHEEECCCCEEEEEEECCCCHHEEEHHHCCCCCCCCCCE
YWIHSDLNQKNIFKKLREKLRLPEEVIQLCGEKDNRSTTIEIDEALTLQIQGLCSMKLND
EEEECCCCHHHHHHHHHHHHCCHHHHHHHCCCCCCCCCEEEECCEEEEEEECEEEEEECC
NYDADFGNLIIHLTPNYCFTASKTLSSVLFDLLKSCPKSLPYAKTSCFLLFLLLEGVIND
CCCCCCCCEEEEECCCCEEHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
YAKIHLAYEELADQLDAQARTTNKNTYSQVLELKHGVMKIKRYTIAIREILMRLTSRNIL
HHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEE
VISEQCRNSLYNLSNHCHLIVNEIDSLRDILNGLLGQIDNQLMQNMNETMRVLTAFAAIF
EEHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LPLSLITGIYGMNFYWMPELGWKYGYFWALGLIVLCALLLFLIFRKKKWF
HHHHHHHHHHCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Ni2; [Periplasm]; Co; 2 [Periplasm]; Mg (II) [Periplasm] [C]

Specific reaction: Ni2+ [Periplasm] = Ni2+ [Cytoplasm] Co+2 [Periplasm] = Co+2 [Cytoplasm] Mg (II) [Periplasm] = Mg (II) [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]