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The map label for this gene is ybeC [H]

Identifier: 52840483

GI number: 52840483

Start: 262200

End: 263765

Strand: Reverse

Name: ybeC [H]

Synonym: lpg0228

Alternate gene names: 52840483

Gene position: 263765-262200 (Counterclockwise)

Preceding gene: 52840484

Following gene: 52840477

Centisome position: 7.76

GC content: 38.51

Gene sequence:

>1566_bases
ATGTTAAAACGGGATATTTCAACCCTGAATATATTAGTTGCATCAGCTGGTGGAATGATTGGTTCAGGTTGGCTGTTCAG
CCCATTTATTAGTGCCCAAATGGCAGGCAGTAATTCTCTGATAAGCTGGGTTATTGCAGCAATATTTATGTTGTTTATTG
CCCTACCGCTTTGTGAACTGGGAACGATGTTTCCAGTTTCCGGGGGTATGTCTAATTATCCTACTTACACACACGGTCGA
GAAGTGGGTTTTTTATTCGCATGGACATCCTGGTTATCTTATGTTGTTATGACACCTATTGAGATACAAGCAATTTTGCA
ATATTCAAGTCATTTTTTTCCAATATTAATCGACAATCATAGCGAATCACTCACACTGTCCAATTATGGTTATCTTGCTG
CAGTTGGGATTATGTTTTTCGTAGTTATTTTGAATTCTTATGGGATTAAGTTTTTAGCCGAGTGTAACAAGTATGCCAGC
GTCATTAAATTTGTTTTGCCGAGTATCGCTATTATCTCACTGTTAAAGCAATCACCCTCTCTTGCTAATGTTAATATTAA
TCTGTCAAGCAAAGAACACTGGGTAGAGATATTTACCGCTCTTTCTGCAGGCGGGGTAGCTTTTGCTTTTACAGGGTTTC
AAAATGGTTTAATCCTGGCAGGAGAAGTTAAAAATCCACAACGAAATATTCCTATTGCCATACTTGGCGCGGTATTGGTT
GGCTTTATTCTTTATTTTATGTTGCAGTTCAGTTTTATAGCGGCGGTACCACAAAAGTATTTGGCTCAAGGTTGGCACGC
ATTGAGTTACCCCGGTGATGAAGGTCCATTGGTTGGATTAACTCTTTTGTTAGGACTTGGCATTGTTGCTACTCTGTTAT
TGTTTGACGCCGCTTTTTCTCCTTTTGGCACGACTTTAGTTTATACCGCAGCTACATCTCGTATTTTGTATGGCATGGCA
TTAAACCAACATTTGCCCAAGTTTTTCTTAAAGGTCAACCGCCATAACATACCTTACGTAACACTTTATGCAAATCTTTT
GGTTGGTTCTTTTGCATTCTTACCCTTTCCGGGATGGCAAAAACTAGTGGCATTCCTTTCATCAGCAAGTATTTTATCCT
ACGGAATTGGCCCGATTTGTCTCTTGGCCATGCGTAAAATGCACCCCCATATGAATAGACCCTTCAAGCTCGCAAATAGT
ATTTTCTTGTCACATATCGCCTTTTATATATGTAATCTCATGTTGTACTGGTGTGGTTTTTCTATTATTTGGAAGCTAAA
CTTAGCATTGCTTATGGGGCTTGGTATTTACTTTTTTTACCATCGCTATATTTCTTTGAGAAATGGCTCGCCTCTGGTGT
GGTTTATCATGTACATGGGATCATTTTCTATTATTTCTTATTTAGGATCTTTTGGCGGCATTGGTTTACTGAAATTCCCT
TTCGATTTAATCTGCTTCTTGCCTTATAGTATTTTAATACTTTACATGTCTCAAGTTTTAGCGACACCCCGTCATGACAA
TGACATGATTGGTAATGTTACAGAATTGCCAGTATACAATTCTTGA

Upstream 100 bases:

>100_bases
TGATTTATTTCTTTATATATAATCATTACCCACTTTTATAGAAATTTGAACAATATCGAACAGATAGTGTTGTTTTGATA
AACAAATGGAACAGTAACAG

Downstream 100 bases:

>100_bases
GGTAGCAAAGCGACAAAGTAAAAACGCTTCCTGATTATCCTTGTCTGTTTTGTAGTTCACTGTCATGACTTCTTATGGGT
AAAATGCATCAAGGGTAACT

Product: amino acid permease family protein

Products: D-glycine [Cytoplasm]; D-alanine [Cytoplasm]; Proton [Cytoplasm]; D-serine [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 521; Mature: 521

Protein sequence:

>521_residues
MLKRDISTLNILVASAGGMIGSGWLFSPFISAQMAGSNSLISWVIAAIFMLFIALPLCELGTMFPVSGGMSNYPTYTHGR
EVGFLFAWTSWLSYVVMTPIEIQAILQYSSHFFPILIDNHSESLTLSNYGYLAAVGIMFFVVILNSYGIKFLAECNKYAS
VIKFVLPSIAIISLLKQSPSLANVNINLSSKEHWVEIFTALSAGGVAFAFTGFQNGLILAGEVKNPQRNIPIAILGAVLV
GFILYFMLQFSFIAAVPQKYLAQGWHALSYPGDEGPLVGLTLLLGLGIVATLLLFDAAFSPFGTTLVYTAATSRILYGMA
LNQHLPKFFLKVNRHNIPYVTLYANLLVGSFAFLPFPGWQKLVAFLSSASILSYGIGPICLLAMRKMHPHMNRPFKLANS
IFLSHIAFYICNLMLYWCGFSIIWKLNLALLMGLGIYFFYHRYISLRNGSPLVWFIMYMGSFSIISYLGSFGGIGLLKFP
FDLICFLPYSILILYMSQVLATPRHDNDMIGNVTELPVYNS

Sequences:

>Translated_521_residues
MLKRDISTLNILVASAGGMIGSGWLFSPFISAQMAGSNSLISWVIAAIFMLFIALPLCELGTMFPVSGGMSNYPTYTHGR
EVGFLFAWTSWLSYVVMTPIEIQAILQYSSHFFPILIDNHSESLTLSNYGYLAAVGIMFFVVILNSYGIKFLAECNKYAS
VIKFVLPSIAIISLLKQSPSLANVNINLSSKEHWVEIFTALSAGGVAFAFTGFQNGLILAGEVKNPQRNIPIAILGAVLV
GFILYFMLQFSFIAAVPQKYLAQGWHALSYPGDEGPLVGLTLLLGLGIVATLLLFDAAFSPFGTTLVYTAATSRILYGMA
LNQHLPKFFLKVNRHNIPYVTLYANLLVGSFAFLPFPGWQKLVAFLSSASILSYGIGPICLLAMRKMHPHMNRPFKLANS
IFLSHIAFYICNLMLYWCGFSIIWKLNLALLMGLGIYFFYHRYISLRNGSPLVWFIMYMGSFSIISYLGSFGGIGLLKFP
FDLICFLPYSILILYMSQVLATPRHDNDMIGNVTELPVYNS
>Mature_521_residues
MLKRDISTLNILVASAGGMIGSGWLFSPFISAQMAGSNSLISWVIAAIFMLFIALPLCELGTMFPVSGGMSNYPTYTHGR
EVGFLFAWTSWLSYVVMTPIEIQAILQYSSHFFPILIDNHSESLTLSNYGYLAAVGIMFFVVILNSYGIKFLAECNKYAS
VIKFVLPSIAIISLLKQSPSLANVNINLSSKEHWVEIFTALSAGGVAFAFTGFQNGLILAGEVKNPQRNIPIAILGAVLV
GFILYFMLQFSFIAAVPQKYLAQGWHALSYPGDEGPLVGLTLLLGLGIVATLLLFDAAFSPFGTTLVYTAATSRILYGMA
LNQHLPKFFLKVNRHNIPYVTLYANLLVGSFAFLPFPGWQKLVAFLSSASILSYGIGPICLLAMRKMHPHMNRPFKLANS
IFLSHIAFYICNLMLYWCGFSIIWKLNLALLMGLGIYFFYHRYISLRNGSPLVWFIMYMGSFSIISYLGSFGGIGLLKFP
FDLICFLPYSILILYMSQVLATPRHDNDMIGNVTELPVYNS

Specific function: Uptake of an yet unknown amino-acid with the concomitant import of a proton [H]

COG id: COG0531

COG function: function code E; Amino acid transporters

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid-polyamine-organocation (APC) superfamily. AGT (TC 2.A.3.11) family [H]

Homologues:

Organism=Homo sapiens, GI4507047, Length=445, Percent_Identity=24.9438202247191, Blast_Score=77, Evalue=5e-14,
Organism=Homo sapiens, GI258645169, Length=431, Percent_Identity=25.5220417633411, Blast_Score=76, Evalue=6e-14,
Organism=Homo sapiens, GI258614003, Length=432, Percent_Identity=24.7685185185185, Blast_Score=70, Evalue=5e-12,
Organism=Homo sapiens, GI258614005, Length=432, Percent_Identity=24.7685185185185, Blast_Score=70, Evalue=5e-12,
Organism=Homo sapiens, GI187423910, Length=413, Percent_Identity=24.9394673123487, Blast_Score=69, Evalue=8e-12,
Organism=Homo sapiens, GI7657591, Length=413, Percent_Identity=24.9394673123487, Blast_Score=69, Evalue=8e-12,
Organism=Homo sapiens, GI186910308, Length=428, Percent_Identity=25, Blast_Score=68, Evalue=2e-11,
Organism=Homo sapiens, GI186910306, Length=428, Percent_Identity=25, Blast_Score=68, Evalue=2e-11,
Organism=Homo sapiens, GI186910304, Length=428, Percent_Identity=25, Blast_Score=68, Evalue=2e-11,
Organism=Escherichia coli, GI1790653, Length=417, Percent_Identity=22.3021582733813, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI48994972, Length=444, Percent_Identity=25.4504504504505, Blast_Score=76, Evalue=6e-15,
Organism=Escherichia coli, GI87081708, Length=372, Percent_Identity=23.6559139784946, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1786302, Length=407, Percent_Identity=24.0786240786241, Blast_Score=73, Evalue=5e-14,
Organism=Escherichia coli, GI87081915, Length=429, Percent_Identity=22.6107226107226, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI1788480, Length=371, Percent_Identity=23.1805929919137, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1786789, Length=401, Percent_Identity=23.6907730673317, Blast_Score=70, Evalue=4e-13,
Organism=Escherichia coli, GI1786602, Length=352, Percent_Identity=23.0113636363636, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI2367353, Length=333, Percent_Identity=24.024024024024, Blast_Score=66, Evalue=5e-12,
Organism=Escherichia coli, GI1786908, Length=327, Percent_Identity=24.7706422018349, Blast_Score=64, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17533459, Length=405, Percent_Identity=23.7037037037037, Blast_Score=66, Evalue=5e-11,
Organism=Drosophila melanogaster, GI24651635, Length=414, Percent_Identity=25.3623188405797, Blast_Score=78, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24651633, Length=414, Percent_Identity=25.3623188405797, Blast_Score=78, Evalue=2e-14,
Organism=Drosophila melanogaster, GI221331183, Length=414, Percent_Identity=26.8115942028986, Blast_Score=70, Evalue=3e-12,
Organism=Drosophila melanogaster, GI17647653, Length=414, Percent_Identity=26.8115942028986, Blast_Score=70, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24664379, Length=414, Percent_Identity=26.8115942028986, Blast_Score=70, Evalue=3e-12,
Organism=Drosophila melanogaster, GI45550968, Length=475, Percent_Identity=26.1052631578947, Blast_Score=67, Evalue=4e-11,
Organism=Drosophila melanogaster, GI19921172, Length=475, Percent_Identity=26.1052631578947, Blast_Score=67, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004841
- InterPro:   IPR002293 [H]

Pfam domain/function: PF00324 AA_permease [H]

EC number: NA

Molecular weight: Translated: 57688; Mature: 57688

Theoretical pI: Translated: 9.08; Mature: 9.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKRDISTLNILVASAGGMIGSGWLFSPFISAQMAGSNSLISWVIAAIFMLFIALPLCEL
CCCCHHHHHHHHEEECCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
GTMFPVSGGMSNYPTYTHGREVGFLFAWTSWLSYVVMTPIEIQAILQYSSHFFPILIDNH
CCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCEEEEEECC
SESLTLSNYGYLAAVGIMFFVVILNSYGIKFLAECNKYASVIKFVLPSIAIISLLKQSPS
CCEEEECCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
LANVNINLSSKEHWVEIFTALSAGGVAFAFTGFQNGLILAGEVKNPQRNIPIAILGAVLV
EEEEEEEECCHHHHHHHHHHHHCCCEEEEEECCCCCEEEEECCCCCCCCCCHHHHHHHHH
GFILYFMLQFSFIAAVPQKYLAQGWHALSYPGDEGPLVGLTLLLGLGIVATLLLFDAAFS
HHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCC
PFGTTLVYTAATSRILYGMALNQHLPKFFLKVNRHNIPYVTLYANLLVGSFAFLPFPGWQ
CCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCHH
KLVAFLSSASILSYGIGPICLLAMRKMHPHMNRPFKLANSIFLSHIAFYICNLMLYWCGF
HHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
SIIWKLNLALLMGLGIYFFYHRYISLRNGSPLVWFIMYMGSFSIISYLGSFGGIGLLKFP
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHH
FDLICFLPYSILILYMSQVLATPRHDNDMIGNVTELPVYNS
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MLKRDISTLNILVASAGGMIGSGWLFSPFISAQMAGSNSLISWVIAAIFMLFIALPLCEL
CCCCHHHHHHHHEEECCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
GTMFPVSGGMSNYPTYTHGREVGFLFAWTSWLSYVVMTPIEIQAILQYSSHFFPILIDNH
CCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCEEEEEECC
SESLTLSNYGYLAAVGIMFFVVILNSYGIKFLAECNKYASVIKFVLPSIAIISLLKQSPS
CCEEEECCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
LANVNINLSSKEHWVEIFTALSAGGVAFAFTGFQNGLILAGEVKNPQRNIPIAILGAVLV
EEEEEEEECCHHHHHHHHHHHHCCCEEEEEECCCCCEEEEECCCCCCCCCCHHHHHHHHH
GFILYFMLQFSFIAAVPQKYLAQGWHALSYPGDEGPLVGLTLLLGLGIVATLLLFDAAFS
HHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCC
PFGTTLVYTAATSRILYGMALNQHLPKFFLKVNRHNIPYVTLYANLLVGSFAFLPFPGWQ
CCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCHH
KLVAFLSSASILSYGIGPICLLAMRKMHPHMNRPFKLANSIFLSHIAFYICNLMLYWCGF
HHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
SIIWKLNLALLMGLGIYFFYHRYISLRNGSPLVWFIMYMGSFSIISYLGSFGGIGLLKFP
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHH
FDLICFLPYSILILYMSQVLATPRHDNDMIGNVTELPVYNS
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: D-glycine [Periplasm]; D-alanine [Periplasm]; Proton [Periplasm]; D-serine [Periplasm] [C]

Specific reaction: Proton [Periplasm] + D-glycine [Periplasm] = Proton [Cytoplasm] + D-glycine [Cytoplasm] Proton [Periplasm] + D-alanine [Periplasm] = Proton [Cytoplasm] + D-alanine [Cytoplasm] Proton [Periplasm] + D-serine [Periplasm] = Proton [Cytoplasm] + D-serine [Cyto

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377; 12730183 [H]