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The map label for this gene is dapB

Identifier: 52840386

GI number: 52840386

Start: 154334

End: 155065

Strand: Reverse

Name: dapB

Synonym: lpg0131

Alternate gene names: 52840386

Gene position: 155065-154334 (Counterclockwise)

Preceding gene: 52840387

Following gene: 52840384

Centisome position: 4.56

GC content: 40.85

Gene sequence:

>732_bases
ATGCGAACACGTATCATTGTTAATGGTGCCAATGGAAAAATGGGGATACTAGCCTGTGAAACATTGGAAAACCATGAACA
GTTTGAAATAGTAGCCAAACTAAGCAGACAGGACAATCTTGGGCAAAGTATACTGGACACCAAAGCACAAATAGTTGTTG
ATTTGACAAGAGCAGACTGTGTCTATGAAAACTCTTTAACCATTATTAATCACGGCGCTCGACCGGTTATTGGGACATCG
GGGTTGGTTGAAACACAAATCGATGAGCTCACCAAACTGTGTGAAATAAAACAAATAGGTGGAATTATTGCACCTAATTT
TTCTCTCGGTGCCATTTTAATGATGATTCTCGCCACAAAAGCTTCTGAATATTTTTCAGAGGTTGAAATTATTGAAGGCC
ATCATCAACAAAAATTGGATGCGCCATCAGGGACTGCTTTAAAAACTGCAGAAATGATAGCCGCGGCGCGCAAAAAACCC
AAAAACAAACTTCCATTAAAAGAATTAACCCCTGGGGCCCGAGGCGGCTCTCATCATGATATTAATATTCATTCCCTTAG
ACTGCCTGGGTTGCTTGCTCGACAAGAAGTCCTCTTTGGCAACATAGGCGAGACACTCTCCATTACACATAACAGTATAG
ATCGCCGTTGTTTTATGCCGGGAATTGTGCTGGCCTGTCAAAAAGTATTGAATTTAAATAACCTGGTTTATGGTCTGGAA
CATTTGCTTTAA

Upstream 100 bases:

>100_bases
TTAATGAGAGAGTTTAGATAGGCTCAATGACCGAATTAAAAATTTTTTTATAAAGAGATTGGGGTTTTTCGGAAATCATG
TAAATAATTCGGAGTGATAA

Downstream 100 bases:

>100_bases
ATTGCAAAAACCAGGTTGACCCGTATTACTGTCGGGCATACGGGTCTCCTTTTCACATATCACCCCTTGATATGGAACGT
TTCCCAACTCAATTTTTTAA

Product: dihydrodipicolinate reductase

Products: NA

Alternate protein names: DHPR [H]

Number of amino acids: Translated: 243; Mature: 243

Protein sequence:

>243_residues
MRTRIIVNGANGKMGILACETLENHEQFEIVAKLSRQDNLGQSILDTKAQIVVDLTRADCVYENSLTIINHGARPVIGTS
GLVETQIDELTKLCEIKQIGGIIAPNFSLGAILMMILATKASEYFSEVEIIEGHHQQKLDAPSGTALKTAEMIAAARKKP
KNKLPLKELTPGARGGSHHDINIHSLRLPGLLARQEVLFGNIGETLSITHNSIDRRCFMPGIVLACQKVLNLNNLVYGLE
HLL

Sequences:

>Translated_243_residues
MRTRIIVNGANGKMGILACETLENHEQFEIVAKLSRQDNLGQSILDTKAQIVVDLTRADCVYENSLTIINHGARPVIGTS
GLVETQIDELTKLCEIKQIGGIIAPNFSLGAILMMILATKASEYFSEVEIIEGHHQQKLDAPSGTALKTAEMIAAARKKP
KNKLPLKELTPGARGGSHHDINIHSLRLPGLLARQEVLFGNIGETLSITHNSIDRRCFMPGIVLACQKVLNLNNLVYGLE
HLL
>Mature_243_residues
MRTRIIVNGANGKMGILACETLENHEQFEIVAKLSRQDNLGQSILDTKAQIVVDLTRADCVYENSLTIINHGARPVIGTS
GLVETQIDELTKLCEIKQIGGIIAPNFSLGAILMMILATKASEYFSEVEIIEGHHQQKLDAPSGTALKTAEMIAAARKKP
KNKLPLKELTPGARGGSHHDINIHSLRLPGLLARQEVLFGNIGETLSITHNSIDRRCFMPGIVLACQKVLNLNNLVYGLE
HLL

Specific function: Biosynthesis of diaminopimelate and lysine from aspartate semialdehyde; second step. [C]

COG id: COG0289

COG function: function code E; Dihydrodipicolinate reductase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dihydrodipicolinate reductase family [H]

Homologues:

Organism=Escherichia coli, GI1786214, Length=274, Percent_Identity=29.5620437956204, Blast_Score=88, Evalue=5e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022663
- InterPro:   IPR000846
- InterPro:   IPR022664
- InterPro:   IPR011770
- InterPro:   IPR016040 [H]

Pfam domain/function: PF05173 DapB_C; PF01113 DapB_N [H]

EC number: =1.3.1.26 [H]

Molecular weight: Translated: 26543; Mature: 26543

Theoretical pI: Translated: 7.60; Mature: 7.60

Prosite motif: PS01298 DAPB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRTRIIVNGANGKMGILACETLENHEQFEIVAKLSRQDNLGQSILDTKAQIVVDLTRADC
CCCEEEEECCCCCEEEEEECCCCCCHHHHHHHHHHHCCCCCHHHHHCCCEEEEEEHHHCE
VYENSLTIINHGARPVIGTSGLVETQIDELTKLCEIKQIGGIIAPNFSLGAILMMILATK
EECCCEEEEECCCCCEECCCCCHHHHHHHHHHHHHHHHHCCEECCCCCHHHHHHHHHHHH
ASEYFSEVEIIEGHHQQKLDAPSGTALKTAEMIAAARKKPKNKLPLKELTPGARGGSHHD
HHHHHHHHHHHCCCCHHHCCCCCCCHHHHHHHHHHHHHCCCCCCCHHHCCCCCCCCCCCC
INIHSLRLPGLLARQEVLFGNIGETLSITHNSIDRRCFMPGIVLACQKVLNLNNLVYGLE
EEEEEEECCCHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
HLL
HCC
>Mature Secondary Structure
MRTRIIVNGANGKMGILACETLENHEQFEIVAKLSRQDNLGQSILDTKAQIVVDLTRADC
CCCEEEEECCCCCEEEEEECCCCCCHHHHHHHHHHHCCCCCHHHHHCCCEEEEEEHHHCE
VYENSLTIINHGARPVIGTSGLVETQIDELTKLCEIKQIGGIIAPNFSLGAILMMILATK
EECCCEEEEECCCCCEECCCCCHHHHHHHHHHHHHHHHHCCEECCCCCHHHHHHHHHHHH
ASEYFSEVEIIEGHHQQKLDAPSGTALKTAEMIAAARKKPKNKLPLKELTPGARGGSHHD
HHHHHHHHHHHCCCCHHHCCCCCCCHHHHHHHHHHHHHCCCCCCCHHHCCCCCCCCCCCC
INIHSLRLPGLLARQEVLFGNIGETLSITHNSIDRRCFMPGIVLACQKVLNLNNLVYGLE
EEEEEEECCCHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
HLL
HCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA