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The map label for this gene is nagB [H]

Identifier: 52788021

GI number: 52788021

Start: 4195087

End: 4195833

Strand: Direct

Name: nagB [H]

Synonym: BLi04349

Alternate gene names: 52788021

Gene position: 4195087-4195833 (Clockwise)

Preceding gene: 52788020

Following gene: 52788022

Centisome position: 99.35

GC content: 49.0

Gene sequence:

>747_bases
ATGAAGATCATTGAAGCTAAAGATTATCAGGACATGAGCCAATCAGCCGCCCGATTCATCATCGAGCAAGTGAATCGCTT
ATCTGCACCTGTTCTCGGCCTTGCAACCGGAGGAACGCCTCTCGGCACATATCAGGTTTTAAGGGAAGATCATGCGCGTA
ATAAAACGACTTACAAGCACGTCTATACTGTTAACTTAGACGAGTATGTCGGCGTTTCCCCGGATCATGAAAACAGCTAT
ACATTCTATATGAAAAAACAGCTTTTCGATCACATTGACATCCCGCTCAGCCACACCCATCTTCCGAACGGGATGGCTTG
TGACCTGGATGCCGAATGCAGCCGCTATGAAGCGCTGATCGAGCGGCTTGGAGGCATTGATCTTCAAGTGCTCGGCCTCG
GCTTGAACGGCCACATCGGATTTAACGAGCCGGGCACCCCATTTTCATCGAAAACGCATACGGTTGAACTGACACAATCA
ACGAAAGAAGCCAATGCCCGCTATTTTGATTCCTATGACGCCGTCCCGTCGCAAGCAATAACGATGGGCATTTCCACGAT
CATGAAAAGCAAGCAGATCCTGCTGCTCGTTTCAGGAGAGAAAAAAGCCGGCATCTTGGCGAAGCTGCTCACTGAAGAAC
CAAATGAAGACACCCCCGCTTCCGTCTTAAAAACGCACCAAGACGTCGTCATCATAGCGGACAGCGATGCTTTATCAATC
GTGAAAGAAAGGGGTATGGCCTTTTGA

Upstream 100 bases:

>100_bases
GCGGGAAAGATGCCGATTTGATCATTTTAAATGAAAAAAATGAAGTTGTGATGACGCTTTGCAAAGGCGTGATTGCTTTC
AGCAAAAGGGAGGTTTCACC

Downstream 100 bases:

>100_bases
TCAAAAAAGATTCCCACATTCCGATTTACTATCAGATTGAGACCGAAATTAAAAAGCTTGCCGAAACAAAAGATTTGAAA
CCCGGCGACCTCATTCCTTC

Product: hypothetical protein

Products: NA

Alternate protein names: GlcN6P deaminase; GNPDA; Glucosamine-6-phosphate isomerase [H]

Number of amino acids: Translated: 248; Mature: 248

Protein sequence:

>248_residues
MKIIEAKDYQDMSQSAARFIIEQVNRLSAPVLGLATGGTPLGTYQVLREDHARNKTTYKHVYTVNLDEYVGVSPDHENSY
TFYMKKQLFDHIDIPLSHTHLPNGMACDLDAECSRYEALIERLGGIDLQVLGLGLNGHIGFNEPGTPFSSKTHTVELTQS
TKEANARYFDSYDAVPSQAITMGISTIMKSKQILLLVSGEKKAGILAKLLTEEPNEDTPASVLKTHQDVVIIADSDALSI
VKERGMAF

Sequences:

>Translated_248_residues
MKIIEAKDYQDMSQSAARFIIEQVNRLSAPVLGLATGGTPLGTYQVLREDHARNKTTYKHVYTVNLDEYVGVSPDHENSY
TFYMKKQLFDHIDIPLSHTHLPNGMACDLDAECSRYEALIERLGGIDLQVLGLGLNGHIGFNEPGTPFSSKTHTVELTQS
TKEANARYFDSYDAVPSQAITMGISTIMKSKQILLLVSGEKKAGILAKLLTEEPNEDTPASVLKTHQDVVIIADSDALSI
VKERGMAF
>Mature_248_residues
MKIIEAKDYQDMSQSAARFIIEQVNRLSAPVLGLATGGTPLGTYQVLREDHARNKTTYKHVYTVNLDEYVGVSPDHENSY
TFYMKKQLFDHIDIPLSHTHLPNGMACDLDAECSRYEALIERLGGIDLQVLGLGLNGHIGFNEPGTPFSSKTHTVELTQS
TKEANARYFDSYDAVPSQAITMGISTIMKSKQILLLVSGEKKAGILAKLLTEEPNEDTPASVLKTHQDVVIIADSDALSI
VKERGMAF

Specific function: Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion [H]

COG id: COG0363

COG function: function code G; 6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily [H]

Homologues:

Organism=Homo sapiens, GI19923881, Length=243, Percent_Identity=38.6831275720165, Blast_Score=180, Evalue=1e-45,
Organism=Homo sapiens, GI13027378, Length=243, Percent_Identity=39.917695473251, Blast_Score=179, Evalue=1e-45,
Organism=Escherichia coli, GI1786893, Length=254, Percent_Identity=36.6141732283465, Blast_Score=181, Evalue=3e-47,
Organism=Escherichia coli, GI1789530, Length=234, Percent_Identity=29.4871794871795, Blast_Score=108, Evalue=3e-25,
Organism=Escherichia coli, GI48994958, Length=235, Percent_Identity=30.2127659574468, Blast_Score=92, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI17554876, Length=242, Percent_Identity=37.1900826446281, Blast_Score=170, Evalue=7e-43,
Organism=Drosophila melanogaster, GI24581960, Length=243, Percent_Identity=39.5061728395062, Blast_Score=196, Evalue=8e-51,
Organism=Drosophila melanogaster, GI19920764, Length=243, Percent_Identity=39.5061728395062, Blast_Score=196, Evalue=8e-51,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006148
- InterPro:   IPR004547
- InterPro:   IPR018321 [H]

Pfam domain/function: PF01182 Glucosamine_iso [H]

EC number: =3.5.99.6 [H]

Molecular weight: Translated: 27345; Mature: 27345

Theoretical pI: Translated: 5.55; Mature: 5.55

Prosite motif: PS01161 GLC_GALNAC_ISOMERASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIIEAKDYQDMSQSAARFIIEQVNRLSAPVLGLATGGTPLGTYQVLREDHARNKTTYKH
CCCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHHCCCCEEEE
VYTVNLDEYVGVSPDHENSYTFYMKKQLFDHIDIPLSHTHLPNGMACDLDAECSRYEALI
EEEEEHHHHCCCCCCCCCCEEEEEHHHHHHHCCCCCCCCCCCCCEEECCCCHHHHHHHHH
ERLGGIDLQVLGLGLNGHIGFNEPGTPFSSKTHTVELTQSTKEANARYFDSYDAVPSQAI
HHHCCCEEEEEEECCCCCCCCCCCCCCCCCCCEEEEEECCCHHCCCEECCCCCCCCHHHH
TMGISTIMKSKQILLLVSGEKKAGILAKLLTEEPNEDTPASVLKTHQDVVIIADSDALSI
HHHHHHHHCCCEEEEEEECCCCHHHHHHHHHCCCCCCCCHHHHHCCCCEEEEECCCHHHH
VKERGMAF
HHHCCCCC
>Mature Secondary Structure
MKIIEAKDYQDMSQSAARFIIEQVNRLSAPVLGLATGGTPLGTYQVLREDHARNKTTYKH
CCCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHHCCCCEEEE
VYTVNLDEYVGVSPDHENSYTFYMKKQLFDHIDIPLSHTHLPNGMACDLDAECSRYEALI
EEEEEHHHHCCCCCCCCCCEEEEEHHHHHHHCCCCCCCCCCCCCEEECCCCHHHHHHHHH
ERLGGIDLQVLGLGLNGHIGFNEPGTPFSSKTHTVELTQSTKEANARYFDSYDAVPSQAI
HHHCCCEEEEEEECCCCCCCCCCCCCCCCCCCEEEEEECCCHHCCCEECCCCCCCCHHHH
TMGISTIMKSKQILLLVSGEKKAGILAKLLTEEPNEDTPASVLKTHQDVVIIADSDALSI
HHHHHHHHCCCEEEEEEECCCCHHHHHHHHHCCCCCCCCHHHHHCCCCEEEEECCCHHHH
VKERGMAF
HHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA