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The map label for this gene is galE [H]

Identifier: 52787960

GI number: 52787960

Start: 4128258

End: 4129259

Strand: Direct

Name: galE [H]

Synonym: BLi04283

Alternate gene names: 52787960

Gene position: 4128258-4129259 (Clockwise)

Preceding gene: 52787959

Following gene: 52787961

Centisome position: 97.76

GC content: 51.0

Gene sequence:

>1002_bases
ATGAGCGTGTTGGTTTTGGGCGGTGCCGGCTATATCGGTTCACACGCCGTGTACCAATTAATAGACAGAGGCGAAAACGT
CGTTGTCGTTGACAACCTCGAGACCGGCCAAAGACAGGCAGTACATCCTGATGCGATCTTTTATGAAGGGGATGTGCGCG
ATCGCGATTTCCTCCGCACGGTTTTCGAAAAGGAACGTATTGAAGAAGTGATCCATTTTGCCGCCAGTTCACTTGTCGGC
GAATCGATGAAAGATCCGCTCAAATATTACGACAACAATGTATCCGGAACACAGGTTTTGCTTCAGGCGATGCTCGAGCA
CGATGTAAAAAAAATCGTATTCTCCTCGACGGCGGCCGTCTACGGAGAGCCTGAATCGTTGCCGATTACAGAAGACATGC
CGACAATGCCGACAAGCACCTACGGGGAAACGAAACTGATCATGGAAAAGCTCATGAAGCGGACTGAAGAAGCCCATGGG
ATCAGCTTTGTGTCTCTCAGGTACTTCAATGTTGCAGGGGCAAGGGAGACGGGAGAAATCGGAGAAGACCACCGTCCGGA
AACACACCTAGTCCCCCTCATCCTGCAGACCGCTCTCGGCCAAAGACCGCATATAACGATTTTCGGCGATGACTATGATA
CGCCCGACGGCACATGCATCCGCGACTATGTTCATGTTGAAGACCTCATTGACGCTCATCTGTCGGCATTAGACTATTTA
AGAAAAGGCGGCAAAAGCGATATATTCAATCTCGGCAGCAGCGAAGGATTTTCGGTGAAAGAAATGATTGATGCGGCCAG
AAAGGCAACCGGGAAAGACATTACCGCCGAGATCGGCAAGCGCAGAGCCGGCGACCCGAGCATCCTGATTGCCGGCTCTC
ACAAGGCAAAGCAAGTTCTGGGCTGGAGGCCTTCGCGCACATCTGTAGCAAAGATTATTGAAGATGCATGGAAGTGGCAT
TCCTCGCATCCAAACGGTTACAGGAAGGAAGTGTCAACATGA

Upstream 100 bases:

>100_bases
GCGTGAATGCCGTCTACCGCGAAACGGTTGGCTATGATGCCGCTTTTTATACTGCGGCAATAGGCGACGGCGCCAAAGAA
ATATAGAAAGGGGAATGGAT

Downstream 100 bases:

>100_bases
TTGAACAAGACATAGCCGGACTCATTCAAAAAGCGCTTGAAGCAGGGTTTATCGAACCGGCTGACGTGAACTACGCGCGC
AACCAAGTGATGAATCTGCT

Product: hypothetical protein

Products: NA

Alternate protein names: Galactowaldenase; UDP-galactose 4-epimerase [H]

Number of amino acids: Translated: 333; Mature: 332

Protein sequence:

>333_residues
MSVLVLGGAGYIGSHAVYQLIDRGENVVVVDNLETGQRQAVHPDAIFYEGDVRDRDFLRTVFEKERIEEVIHFAASSLVG
ESMKDPLKYYDNNVSGTQVLLQAMLEHDVKKIVFSSTAAVYGEPESLPITEDMPTMPTSTYGETKLIMEKLMKRTEEAHG
ISFVSLRYFNVAGARETGEIGEDHRPETHLVPLILQTALGQRPHITIFGDDYDTPDGTCIRDYVHVEDLIDAHLSALDYL
RKGGKSDIFNLGSSEGFSVKEMIDAARKATGKDITAEIGKRRAGDPSILIAGSHKAKQVLGWRPSRTSVAKIIEDAWKWH
SSHPNGYRKEVST

Sequences:

>Translated_333_residues
MSVLVLGGAGYIGSHAVYQLIDRGENVVVVDNLETGQRQAVHPDAIFYEGDVRDRDFLRTVFEKERIEEVIHFAASSLVG
ESMKDPLKYYDNNVSGTQVLLQAMLEHDVKKIVFSSTAAVYGEPESLPITEDMPTMPTSTYGETKLIMEKLMKRTEEAHG
ISFVSLRYFNVAGARETGEIGEDHRPETHLVPLILQTALGQRPHITIFGDDYDTPDGTCIRDYVHVEDLIDAHLSALDYL
RKGGKSDIFNLGSSEGFSVKEMIDAARKATGKDITAEIGKRRAGDPSILIAGSHKAKQVLGWRPSRTSVAKIIEDAWKWH
SSHPNGYRKEVST
>Mature_332_residues
SVLVLGGAGYIGSHAVYQLIDRGENVVVVDNLETGQRQAVHPDAIFYEGDVRDRDFLRTVFEKERIEEVIHFAASSLVGE
SMKDPLKYYDNNVSGTQVLLQAMLEHDVKKIVFSSTAAVYGEPESLPITEDMPTMPTSTYGETKLIMEKLMKRTEEAHGI
SFVSLRYFNVAGARETGEIGEDHRPETHLVPLILQTALGQRPHITIFGDDYDTPDGTCIRDYVHVEDLIDAHLSALDYLR
KGGKSDIFNLGSSEGFSVKEMIDAARKATGKDITAEIGKRRAGDPSILIAGSHKAKQVLGWRPSRTSVAKIIEDAWKWHS
SHPNGYRKEVST

Specific function: Galactose metabolism; third step. [C]

COG id: COG1087

COG function: function code M; UDP-glucose 4-epimerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sugar epimerase family [H]

Homologues:

Organism=Homo sapiens, GI56237023, Length=341, Percent_Identity=40.4692082111437, Blast_Score=250, Evalue=1e-66,
Organism=Homo sapiens, GI56118217, Length=341, Percent_Identity=40.4692082111437, Blast_Score=250, Evalue=1e-66,
Organism=Homo sapiens, GI189083684, Length=341, Percent_Identity=40.4692082111437, Blast_Score=250, Evalue=1e-66,
Organism=Homo sapiens, GI7657641, Length=332, Percent_Identity=27.4096385542169, Blast_Score=111, Evalue=8e-25,
Organism=Homo sapiens, GI42516563, Length=307, Percent_Identity=25.4071661237785, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI193211614, Length=250, Percent_Identity=25.6, Blast_Score=67, Evalue=3e-11,
Organism=Homo sapiens, GI8393516, Length=250, Percent_Identity=25.6, Blast_Score=67, Evalue=3e-11,
Organism=Escherichia coli, GI1786974, Length=339, Percent_Identity=41.8879056047198, Blast_Score=267, Evalue=6e-73,
Organism=Escherichia coli, GI1788353, Length=348, Percent_Identity=28.735632183908, Blast_Score=92, Evalue=4e-20,
Organism=Escherichia coli, GI1790049, Length=270, Percent_Identity=30.3703703703704, Blast_Score=92, Evalue=7e-20,
Organism=Escherichia coli, GI48994969, Length=337, Percent_Identity=29.673590504451, Blast_Score=90, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI71982035, Length=346, Percent_Identity=39.8843930635838, Blast_Score=255, Evalue=2e-68,
Organism=Caenorhabditis elegans, GI71982038, Length=348, Percent_Identity=39.6551724137931, Blast_Score=254, Evalue=4e-68,
Organism=Caenorhabditis elegans, GI17539532, Length=314, Percent_Identity=27.0700636942675, Blast_Score=88, Evalue=6e-18,
Organism=Caenorhabditis elegans, GI17568069, Length=351, Percent_Identity=26.4957264957265, Blast_Score=82, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI115532424, Length=332, Percent_Identity=25.3012048192771, Blast_Score=65, Evalue=5e-11,
Organism=Saccharomyces cerevisiae, GI6319493, Length=344, Percent_Identity=43.3139534883721, Blast_Score=258, Evalue=1e-69,
Organism=Saccharomyces cerevisiae, GI6321437, Length=342, Percent_Identity=24.2690058479532, Blast_Score=63, Evalue=6e-11,
Organism=Drosophila melanogaster, GI19923002, Length=344, Percent_Identity=44.1860465116279, Blast_Score=288, Evalue=3e-78,
Organism=Drosophila melanogaster, GI21356223, Length=312, Percent_Identity=26.2820512820513, Blast_Score=94, Evalue=1e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001509
- InterPro:   IPR005886
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: =5.1.3.2 [H]

Molecular weight: Translated: 36975; Mature: 36844

Theoretical pI: Translated: 5.74; Mature: 5.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVLVLGGAGYIGSHAVYQLIDRGENVVVVDNLETGQRQAVHPDAIFYEGDVRDRDFLRT
CEEEEEECCCCHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCEEEECCCCHHHHHHH
VFEKERIEEVIHFAASSLVGESMKDPLKYYDNNVSGTQVLLQAMLEHDVKKIVFSSTAAV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCHHC
YGEPESLPITEDMPTMPTSTYGETKLIMEKLMKRTEEAHGISFVSLRYFNVAGARETGEI
CCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEEEEECCCCCCCCCC
GEDHRPETHLVPLILQTALGQRPHITIFGDDYDTPDGTCIRDYVHVEDLIDAHLSALDYL
CCCCCCCHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
RKGGKSDIFNLGSSEGFSVKEMIDAARKATGKDITAEIGKRRAGDPSILIAGSHKAKQVL
HCCCCCCHHCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHCCCCCCCCEEEECCCHHHHHH
GWRPSRTSVAKIIEDAWKWHSSHPNGYRKEVST
CCCCCHHHHHHHHHHHHHHCCCCCCCCHHCCCC
>Mature Secondary Structure 
SVLVLGGAGYIGSHAVYQLIDRGENVVVVDNLETGQRQAVHPDAIFYEGDVRDRDFLRT
EEEEEECCCCHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCEEEECCCCHHHHHHH
VFEKERIEEVIHFAASSLVGESMKDPLKYYDNNVSGTQVLLQAMLEHDVKKIVFSSTAAV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCHHC
YGEPESLPITEDMPTMPTSTYGETKLIMEKLMKRTEEAHGISFVSLRYFNVAGARETGEI
CCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEEEEECCCCCCCCCC
GEDHRPETHLVPLILQTALGQRPHITIFGDDYDTPDGTCIRDYVHVEDLIDAHLSALDYL
CCCCCCCHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
RKGGKSDIFNLGSSEGFSVKEMIDAARKATGKDITAEIGKRRAGDPSILIAGSHKAKQVL
HCCCCCCHHCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHCCCCCCCCEEEECCCHHHHHH
GWRPSRTSVAKIIEDAWKWHSSHPNGYRKEVST
CCCCCHHHHHHHHHHHHHHCCCCCCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9603808 [H]