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The map label for this gene is lanA1

Identifier: 52787804

GI number: 52787804

Start: 3949652

End: 3949876

Strand: Direct

Name: lanA1

Synonym: BLi04127

Alternate gene names: 52787804

Gene position: 3949652-3949876 (Clockwise)

Preceding gene: 52787792

Following gene: 52787805

Centisome position: 93.54

GC content: 43.56

Gene sequence:

>225_bases
ATGTCAAAAAAGGAAATGATTCTTTCATGGAAAAATCCTATGTATCGCACTGAATCTTCTTATCATCCAGCAGGGAACAT
CCTTAAAGAACTCCAGGAAGAGGAACAGCACAGCATCGCCGGAGGCACAATCACGCTCAGCACTTGTGCCATCTTGAGCA
AGCCGTTAGGAAATAACGGATACCTGTGTACAGTGACAAAAGAATGCATGCCAAGCTGTAACTAA

Upstream 100 bases:

>100_bases
TTCCTATAATTTAGAATTGACTCGCCGTTCCAGTCAAATTATACTATAAGTACATCAAGAAATCGACAAAAAATTATAAA
TTTTCTAGGAGGTGGAATAT

Downstream 100 bases:

>100_bases
GTTCCCAACGCGGGGGCCCTGCTCCCGCGTTGGCATATTGATAGAAAAAGAGGTCGATAGAATGAATGAAAAATCCGCCG
GATATCACGAACGGCTTCCC

Product: hypothetical protein

Products: NA

Alternate protein names: LchA1; BliA1

Number of amino acids: Translated: 74; Mature: 73

Protein sequence:

>74_residues
MSKKEMILSWKNPMYRTESSYHPAGNILKELQEEEQHSIAGGTITLSTCAILSKPLGNNGYLCTVTKECMPSCN

Sequences:

>Translated_74_residues
MSKKEMILSWKNPMYRTESSYHPAGNILKELQEEEQHSIAGGTITLSTCAILSKPLGNNGYLCTVTKECMPSCN
>Mature_73_residues
SKKEMILSWKNPMYRTESSYHPAGNILKELQEEEQHSIAGGTITLSTCAILSKPLGNNGYLCTVTKECMPSCN

Specific function: Lanthionine-containing peptide antibiotic (lantibiotic) active on Gram-positive bacteria. The bactericidal activity of lantibiotics is based on depolarization of energized bacterial cytoplasmic membranes, initiated by the formation of aqueous transmembran

COG id: NA

COG function: NA

Gene ontology:

Cell location: Secreted, cell wall

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): LANLA_BACLD (Q65DC4)

Other databases:

- EMBL:   CP000002
- EMBL:   AE017333
- RefSeq:   YP_081204.1
- RefSeq:   YP_093633.1
- PDB:   2KTN
- PDBsum:   2KTN
- STRING:   Q65DC4
- EnsemblBacteria:   EBBACT00000057972
- EnsemblBacteria:   EBBACT00000059693
- GeneID:   3028214
- GeneID:   3098606
- GenomeReviews:   AE017333_GR
- GenomeReviews:   CP000002_GR
- KEGG:   bld:BLi04127
- KEGG:   bli:BL05375
- NMPDR:   fig|279010.5.peg.3936
- GeneTree:   EBGT00050000006282
- HOGENOM:   HBG033180
- OMA:   ECMPSCN
- ProtClustDB:   CLSK237184
- BioCyc:   BLIC279010-1:BLI04127-MONOMER
- BioCyc:   BLIC279010:BL05375-MONOMER
- GO:   GO:0019835

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 8209; Mature: 8077

Theoretical pI: Translated: 7.29; Mature: 7.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

5.4 %Cys     (Translated Protein)
5.4 %Met     (Translated Protein)
10.8 %Cys+Met (Translated Protein)
5.5 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
9.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKKEMILSWKNPMYRTESSYHPAGNILKELQEEEQHSIAGGTITLSTCAILSKPLGNNG
CCCCCEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHCCCCCCC
YLCTVTKECMPSCN
EEEEEEHHCCCCCC
>Mature Secondary Structure 
SKKEMILSWKNPMYRTESSYHPAGNILKELQEEEQHSIAGGTITLSTCAILSKPLGNNG
CCCCEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHCCCCCCC
YLCTVTKECMPSCN
EEEEEEHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA