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The map label for this gene is katA [H]

Identifier: 52787790

GI number: 52787790

Start: 3934924

End: 3936381

Strand: Direct

Name: katA [H]

Synonym: BLi04113

Alternate gene names: 52787790

Gene position: 3934924-3936381 (Clockwise)

Preceding gene: 52787787

Following gene: 52787791

Centisome position: 93.19

GC content: 49.66

Gene sequence:

>1458_bases
ATGACGACAAATAAAAACAACCTAACAACCAGCTGGGGCGCTCCAGTTGGAGACAACCAAAACTCAATGACAGCTGGTTC
ACGCGGACCGACGCTGATTCAGGACGTCCACTTGCTCGAAAAGCTCGCCCACTTCAATAGAGAGCGTGTGCCTGAACGGG
TTGTGCATGCAAAAGGCGCCGGTGCGCACGGTTATTTTGAAGTCACAAATGACGTTTCCAAATATACAAAAGCCAAATTT
TTATCAGAAGTCGGAAAACGCACGCCGTTATTTGTCCGTTTTTCAACTGTTGCCGGCGAAAACGGTTCAGCCGATTCCGT
CCGCGACCCGCGCGGTTTCGCTGTTAAATTTTATACAGAGGAAGGGAACTATGATCTCGTTGGAAACAATACACCTGTTT
TCTTTATCCGCGATGCGATTAAATTCCCTGACTTCATTCATACACAAAAGCGCCATCCGGTCACACATTTGAAAAACCCG
GATGCCGTATGGGATTTTTGGTCATTGTCTCCTGAATCCCTGCACCAGGTAACCATCCTGATGTCTGACAGGGGCATCCC
TGCGACTTACCGGCACATGCACGGCTTCGGCTCCCACACATTCAAATGGGTGAATGCCGAAGGAGAAGGCGTCTGGATCA
AATACCACTTCAAAACAGAACAAGGCATTAAAAACCTGACCGAAGAAGTGGGGACAAAGATTGCAGGTGAAAACCCCGAT
TATCACACACAGGACTTGTATGAGGCGATTGAAAAAGGCGACTTCCCGGCATGGAAGCTGTACGTTCAAATAATGCCGCT
GGAGGATGCGGATACGTACCGTTTTGATCCGTTCGATGTGACAAAAGTATGGTCGCAAAAAGATTATCCGCTGATTGAAG
TCGGCCGCATGGTTCTAAACCGGAATCCGGAAAACTATTTCGCAGAGGTTGAACAAGCTACATTCTCCCCTGGAACATTG
GTGCCCGGCATTGAACCGTCTCCCGACAAAATGCTTCAGGGACGCCTGTTCGCATATGCGGATGCACACCGCTACCGCGT
CGGCGCAAACCATAACAGCCTGCCGATCAACCGTCCGAAAGCGGAAGTTCATAATTATCAAAGAGACGGACAAATGCGCT
TTGATTCAAACGGCGGCGGCTCTGTCTACTATGAGCCGAACAGCTTCGGAGGCCCTCAGGAAACTCCGGAAAACAAAACA
ACGGCTTATCCGGTGTCAGGTTCGGCGGACAGCACGGCCTACGACCATAACGACCACTATACACAGGCCGGAGATCTTTA
CCGCCTCTTGAGCGAAGAAGAGCGGACCCGCCTTGTCAGCAATATCGTAGGTTCGATGAAGCAGGTGACAAAAGACGAAA
TTAAGCTTCGTCAAATTCAGCATTTCTATAAAGCAGATCCGGAGTACGGCACACGAGTTGCCGAAGGATTGGGCTTGTCT
GTTCCGCAGGAAGTTTAA

Upstream 100 bases:

>100_bases
AATAAATTTTTCTTTATAATAATTATAAATAAATATTGTTTTTTTCTTGAGAAATGTTATCATTGTTTTGTAATTAAAAT
TTACGCGAGGTGATCCTTTG

Downstream 100 bases:

>100_bases
GGCTAATATCATTTCAATCATTCTCAATGAAATTCTCATTTTCTCAGGTACAGGCACCCGTCCTCTTAAGCATGCGGGTG
CCTGCCCTTAATCAAAGAAC

Product: KatA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 485; Mature: 484

Protein sequence:

>485_residues
MTTNKNNLTTSWGAPVGDNQNSMTAGSRGPTLIQDVHLLEKLAHFNRERVPERVVHAKGAGAHGYFEVTNDVSKYTKAKF
LSEVGKRTPLFVRFSTVAGENGSADSVRDPRGFAVKFYTEEGNYDLVGNNTPVFFIRDAIKFPDFIHTQKRHPVTHLKNP
DAVWDFWSLSPESLHQVTILMSDRGIPATYRHMHGFGSHTFKWVNAEGEGVWIKYHFKTEQGIKNLTEEVGTKIAGENPD
YHTQDLYEAIEKGDFPAWKLYVQIMPLEDADTYRFDPFDVTKVWSQKDYPLIEVGRMVLNRNPENYFAEVEQATFSPGTL
VPGIEPSPDKMLQGRLFAYADAHRYRVGANHNSLPINRPKAEVHNYQRDGQMRFDSNGGGSVYYEPNSFGGPQETPENKT
TAYPVSGSADSTAYDHNDHYTQAGDLYRLLSEEERTRLVSNIVGSMKQVTKDEIKLRQIQHFYKADPEYGTRVAEGLGLS
VPQEV

Sequences:

>Translated_485_residues
MTTNKNNLTTSWGAPVGDNQNSMTAGSRGPTLIQDVHLLEKLAHFNRERVPERVVHAKGAGAHGYFEVTNDVSKYTKAKF
LSEVGKRTPLFVRFSTVAGENGSADSVRDPRGFAVKFYTEEGNYDLVGNNTPVFFIRDAIKFPDFIHTQKRHPVTHLKNP
DAVWDFWSLSPESLHQVTILMSDRGIPATYRHMHGFGSHTFKWVNAEGEGVWIKYHFKTEQGIKNLTEEVGTKIAGENPD
YHTQDLYEAIEKGDFPAWKLYVQIMPLEDADTYRFDPFDVTKVWSQKDYPLIEVGRMVLNRNPENYFAEVEQATFSPGTL
VPGIEPSPDKMLQGRLFAYADAHRYRVGANHNSLPINRPKAEVHNYQRDGQMRFDSNGGGSVYYEPNSFGGPQETPENKT
TAYPVSGSADSTAYDHNDHYTQAGDLYRLLSEEERTRLVSNIVGSMKQVTKDEIKLRQIQHFYKADPEYGTRVAEGLGLS
VPQEV
>Mature_484_residues
TTNKNNLTTSWGAPVGDNQNSMTAGSRGPTLIQDVHLLEKLAHFNRERVPERVVHAKGAGAHGYFEVTNDVSKYTKAKFL
SEVGKRTPLFVRFSTVAGENGSADSVRDPRGFAVKFYTEEGNYDLVGNNTPVFFIRDAIKFPDFIHTQKRHPVTHLKNPD
AVWDFWSLSPESLHQVTILMSDRGIPATYRHMHGFGSHTFKWVNAEGEGVWIKYHFKTEQGIKNLTEEVGTKIAGENPDY
HTQDLYEAIEKGDFPAWKLYVQIMPLEDADTYRFDPFDVTKVWSQKDYPLIEVGRMVLNRNPENYFAEVEQATFSPGTLV
PGIEPSPDKMLQGRLFAYADAHRYRVGANHNSLPINRPKAEVHNYQRDGQMRFDSNGGGSVYYEPNSFGGPQETPENKTT
AYPVSGSADSTAYDHNDHYTQAGDLYRLLSEEERTRLVSNIVGSMKQVTKDEIKLRQIQHFYKADPEYGTRVAEGLGLSV
PQEV

Specific function: Decomposes hydrogen peroxide into water and oxygen; serves to protect cells from the toxic effects of hydrogen peroxide [H]

COG id: COG0753

COG function: function code P; Catalase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the catalase family [H]

Homologues:

Organism=Homo sapiens, GI4557014, Length=472, Percent_Identity=58.0508474576271, Blast_Score=578, Evalue=1e-165,
Organism=Escherichia coli, GI48994891, Length=492, Percent_Identity=45.5284552845528, Blast_Score=417, Evalue=1e-118,
Organism=Caenorhabditis elegans, GI71998444, Length=468, Percent_Identity=55.982905982906, Blast_Score=558, Evalue=1e-159,
Organism=Caenorhabditis elegans, GI25147792, Length=474, Percent_Identity=54.8523206751055, Blast_Score=535, Evalue=1e-152,
Organism=Caenorhabditis elegans, GI25151141, Length=474, Percent_Identity=54.6413502109705, Blast_Score=534, Evalue=1e-152,
Organism=Saccharomyces cerevisiae, GI6320462, Length=385, Percent_Identity=54.2857142857143, Blast_Score=426, Evalue=1e-120,
Organism=Saccharomyces cerevisiae, GI6321525, Length=511, Percent_Identity=38.3561643835616, Blast_Score=357, Evalue=2e-99,
Organism=Drosophila melanogaster, GI17981717, Length=484, Percent_Identity=54.7520661157025, Blast_Score=559, Evalue=1e-159,
Organism=Drosophila melanogaster, GI19920968, Length=478, Percent_Identity=48.5355648535565, Blast_Score=494, Evalue=1e-140,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002226
- InterPro:   IPR020835
- InterPro:   IPR010582
- InterPro:   IPR018028
- InterPro:   IPR011614 [H]

Pfam domain/function: PF00199 Catalase; PF06628 Catalase-rel [H]

EC number: =1.11.1.6 [H]

Molecular weight: Translated: 54836; Mature: 54704

Theoretical pI: Translated: 6.47; Mature: 6.47

Prosite motif: PS00437 CATALASE_1 ; PS00438 CATALASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTNKNNLTTSWGAPVGDNQNSMTAGSRGPTLIQDVHLLEKLAHFNRERVPERVVHAKGA
CCCCCCCEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCHHHHHHHHHHCCCC
GAHGYFEVTNDVSKYTKAKFLSEVGKRTPLFVRFSTVAGENGSADSVRDPRGFAVKFYTE
CCCCEEEEHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCCCCCCCCCCEEEEEEEE
EGNYDLVGNNTPVFFIRDAIKFPDFIHTQKRHPVTHLKNPDAVWDFWSLSPESLHQVTIL
CCCEEEECCCCCEEEEECCCCCCHHHHCCCCCCCCCCCCCCCEEHHHCCCHHHHEEEEEE
MSDRGIPATYRHMHGFGSHTFKWVNAEGEGVWIKYHFKTEQGIKNLTEEVGTKIAGENPD
EECCCCCHHHHHHHCCCCCEEEEEECCCCEEEEEEEECCHHHHHHHHHHHCCEECCCCCC
YHTQDLYEAIEKGDFPAWKLYVQIMPLEDADTYRFDPFDVTKVWSQKDYPLIEVGRMVLN
CCHHHHHHHHHHCCCCEEEEEEEEEECCCCCCEECCCCCHHHHHCCCCCCHHHHHHHHHC
RNPENYFAEVEQATFSPGTLVPGIEPSPDKMLQGRLFAYADAHRYRVGANHNSLPINRPK
CCCHHHHHHHHHHCCCCCCCCCCCCCCHHHHHCCEEEEEECCCEEEECCCCCCCCCCCCH
AEVHNYQRDGQMRFDSNGGGSVYYEPNSFGGPQETPENKTTAYPVSGSADSTAYDHNDHY
HHHHCCCCCCCEEEECCCCCEEEECCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCC
TQAGDLYRLLSEEERTRLVSNIVGSMKQVTKDEIKLRQIQHFYKADPEYGTRVAEGLGLS
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCC
VPQEV
CCCCC
>Mature Secondary Structure 
TTNKNNLTTSWGAPVGDNQNSMTAGSRGPTLIQDVHLLEKLAHFNRERVPERVVHAKGA
CCCCCCEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCHHHHHHHHHHCCCC
GAHGYFEVTNDVSKYTKAKFLSEVGKRTPLFVRFSTVAGENGSADSVRDPRGFAVKFYTE
CCCCEEEEHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCCCCCCCCCCEEEEEEEE
EGNYDLVGNNTPVFFIRDAIKFPDFIHTQKRHPVTHLKNPDAVWDFWSLSPESLHQVTIL
CCCEEEECCCCCEEEEECCCCCCHHHHCCCCCCCCCCCCCCCEEHHHCCCHHHHEEEEEE
MSDRGIPATYRHMHGFGSHTFKWVNAEGEGVWIKYHFKTEQGIKNLTEEVGTKIAGENPD
EECCCCCHHHHHHHCCCCCEEEEEECCCCEEEEEEEECCHHHHHHHHHHHCCEECCCCCC
YHTQDLYEAIEKGDFPAWKLYVQIMPLEDADTYRFDPFDVTKVWSQKDYPLIEVGRMVLN
CCHHHHHHHHHHCCCCEEEEEEEEEECCCCCCEECCCCCHHHHHCCCCCCHHHHHHHHHC
RNPENYFAEVEQATFSPGTLVPGIEPSPDKMLQGRLFAYADAHRYRVGANHNSLPINRPK
CCCHHHHHHHHHHCCCCCCCCCCCCCCHHHHHCCEEEEEECCCEEEECCCCCCCCCCCCH
AEVHNYQRDGQMRFDSNGGGSVYYEPNSFGGPQETPENKTTAYPVSGSADSTAYDHNDHY
HHHHCCCCCCCEEEECCCCCEEEECCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCC
TQAGDLYRLLSEEERTRLVSNIVGSMKQVTKDEIKLRQIQHFYKADPEYGTRVAEGLGLS
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCC
VPQEV
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1756979; 9202460; 9384377; 8180695; 10658653 [H]