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The map label for this gene is vpr [H]

Identifier: 52787696

GI number: 52787696

Start: 3843061

End: 3845469

Strand: Direct

Name: vpr [H]

Synonym: BLi04019

Alternate gene names: 52787696

Gene position: 3843061-3845469 (Clockwise)

Preceding gene: 52787691

Following gene: 52787697

Centisome position: 91.01

GC content: 49.44

Gene sequence:

>2409_bases
TTGAGAAAAAGTATCGTGCGCTATTTTGTTATGGCTTTTATTCTATTATTTGCGTTATCCACATTCCTCACCGGAGTGCA
GGCAACTTCCGTTCCCGATAAAAAGTCGCCTGAGCTTGAGAAAGCTGAAATCTACGGTGATATTGATGTGACGTCTGATA
AACAGACGACGGTTATCGTGGAACTGAAAGAAAAGTCGCTTGCCGAAGCAAAAGCGGACGGAGAAAAACAAACGAAGGCT
TCTCTAAAAACAGCTCGAAGCAAAGCGCTGAAAACACTTAAAAAAGCGAAAGTAAACCGCGAATACGACCGTGTATTTTC
GGGCTTTTCTATGAAACTGCCGGCCAGTGAAATTCCAAAGCTGCTCGCCGTCAAGGAAGTTAAAGCGGTTTATCCAAACG
CAACTTACAAACCTGACAGCGTAAAAGGAAAAGACGTGACACTTGCAGCAGACGCCATTTATCCACAGATGGATAAAAGT
GCCCCGTTCATCGGAGCGGATCAGGCATGGAAATCGGGCTATACCGGTAAAGGCATTAAGGTAGCCGTTATTGATACGGG
CGTGGATTACACCCATCCCGACTTAAAGAATAATTTCGGCCCATATAAGGGCTATGACTTTGTGGATAATGATTATGATC
CACAGGAAACACCGACAGGCGACCCGCGCGGCGGAGCGACTGATCACGGCACTCATGTTGCAGGAACAATCGCCGCGAAC
GGACAGATTAAAGGCGTGGCGCCTGAAGCAACGCTTCTTGCTTACCGCGTGCTCGGCCCCGGCGGCTCAGGCACAACCGA
GAATGTGATTGCGGGCATTGAAAAAGCCGTTGCAGACGGAGCAAAAGTGATGAACCTCTCATTGGGAAATTCGCTGAACA
GCCCTGATTATGCAACAAGCATCGCACTGGACTGGGCGATGGCTGAAGGGGTTGTCGCCGTTACGTCAAACGGTAACAGC
GGACCGGAAAACTGGACGGTCGGCTCGCCGGGAACATCAAGGGTTGCGATTTCCGTCGGCGCATCACAGCTTCCGTATAA
TGAGTATTCGGTGACGCTTCCTTCGTATTCATCAGCAAAGGTGATGGGATACCAAGAGGAAAAGGATCTTGAAGCATTGA
ACGGTCAAGAGGTGGAACTCGTTGAAGCCGGCCTCGGACAAGCTGACGATTTCTCAGGCAAAGATGTGAAAGGAAAAGTT
GCGGTTATCCAGAGAGGCGTCATACCATTTGTTGATAAGGCTGAAAATGCCAAAAACGCCGGCGCTATCGGAGCCGTGAT
TTACAATAATGCAACAGGGGAAATCGAGGCAAACGTCATGGGGATGGCCGTACCGACCGTCAAATTGTCAAAAGAAGAGG
GCGAAAAGCTTGTTCAACAGATCAAAGAAGGGAAACACTCCGTTGTCTTTTCTTTCAAATTGGACAAAAAGCTGGGGGAA
ACAATTGCCTCATTCTCGTCCCGCGGGCCTGTCATGGATACATGGATGATTAAACCTGACGTTTCAGCGCCAGGCGTCAA
CATCGTCAGCACCATTCCGACCCACGATCCGAAAAACCCGTACGGTTACGGTTCAAAACAGGGAACAAGCATGGCTTCCC
CGCATGTCGCGGGAACGGCAGCCATATTAAAGCAGGCCAAACCGGATTGGACGCCTGAGCAAATCAAAGGCGTACTGATG
AATACGGCGGAAAAACTGACGGATGAAAATGGAAAGCCTCTCCCTCACAATACGCAAGGAGCGGGCAGCATCCGCATCAT
GGAGGCCCTTAAAGCTTCATCCATTGTAACGCCGGGCAGCCATTCATACGGAACATTCCTGAAAGACAAAGGGAAACAGA
CGAAAAAACAAGCGTTCACGATTGAAAACCTTTCTTCACACAGAAAAGCCTATCAGCTCGAATACTCCTTTAAAGGAACG
GGCATCACGGTATCAGGAACGGAACGAGTCGTGGTACCGGCCAATCAAACAGGTAAAGCAGCGGCAAAAGTAACCGTCAA
TTCCGCGAAAACGAAAGCAGGCACATATGAAGGCACGGTTTACATCCGTGAAGACGGAAGAAAAGTCGCCGAAATCCCGC
TCCTATTGATCGTCAAAGAGCCAGACTACCCGCGCGTCACATCCGTAACAGTTGAACCGGGAGCAAAGCAGGGCGCTTAC
ACGATCGAAGCCTACCTGCCGGGCGGGGCTGAAGAGCTCGCATTTCTCGTCTATGATGAAAACCTGAACCTTCTCGGCCA
GGCCGGCGTTTACAAAAACCAGGGCAAAGGCTATCAATCTTATCAATGGAACGGCAAAATCAATGACGCCGCATCCCTTA
AGTCCGGAAAATACTATATGCTTGCCTATGCATCCGCCAAAGGGAAATCAAGCTACGTATTGACGGAAGACCCTTTTATC
GTCGAATAA

Upstream 100 bases:

>100_bases
TCTATATATAGAAGGATTTTTTTGAAACTGAGAGAATATTTTAAAAGTTCGAAACTCTAATAATTACAAAGAAACATTTA
TCCAGAAGGGGGAAAACAGA

Downstream 100 bases:

>100_bases
TGACAAGCCTTGTTGAGAACCACTCAACAAGGCTTTTTTATGTTAAAATACGGATAATGCGTTCAGGAGAAGCTCCCCCT
TCTCTTCAAAACGTGAAAAA

Product: Vpr

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 802; Mature: 802

Protein sequence:

>802_residues
MRKSIVRYFVMAFILLFALSTFLTGVQATSVPDKKSPELEKAEIYGDIDVTSDKQTTVIVELKEKSLAEAKADGEKQTKA
SLKTARSKALKTLKKAKVNREYDRVFSGFSMKLPASEIPKLLAVKEVKAVYPNATYKPDSVKGKDVTLAADAIYPQMDKS
APFIGADQAWKSGYTGKGIKVAVIDTGVDYTHPDLKNNFGPYKGYDFVDNDYDPQETPTGDPRGGATDHGTHVAGTIAAN
GQIKGVAPEATLLAYRVLGPGGSGTTENVIAGIEKAVADGAKVMNLSLGNSLNSPDYATSIALDWAMAEGVVAVTSNGNS
GPENWTVGSPGTSRVAISVGASQLPYNEYSVTLPSYSSAKVMGYQEEKDLEALNGQEVELVEAGLGQADDFSGKDVKGKV
AVIQRGVIPFVDKAENAKNAGAIGAVIYNNATGEIEANVMGMAVPTVKLSKEEGEKLVQQIKEGKHSVVFSFKLDKKLGE
TIASFSSRGPVMDTWMIKPDVSAPGVNIVSTIPTHDPKNPYGYGSKQGTSMASPHVAGTAAILKQAKPDWTPEQIKGVLM
NTAEKLTDENGKPLPHNTQGAGSIRIMEALKASSIVTPGSHSYGTFLKDKGKQTKKQAFTIENLSSHRKAYQLEYSFKGT
GITVSGTERVVVPANQTGKAAAKVTVNSAKTKAGTYEGTVYIREDGRKVAEIPLLLIVKEPDYPRVTSVTVEPGAKQGAY
TIEAYLPGGAEELAFLVYDENLNLLGQAGVYKNQGKGYQSYQWNGKINDAASLKSGKYYMLAYASAKGKSSYVLTEDPFI
VE

Sequences:

>Translated_802_residues
MRKSIVRYFVMAFILLFALSTFLTGVQATSVPDKKSPELEKAEIYGDIDVTSDKQTTVIVELKEKSLAEAKADGEKQTKA
SLKTARSKALKTLKKAKVNREYDRVFSGFSMKLPASEIPKLLAVKEVKAVYPNATYKPDSVKGKDVTLAADAIYPQMDKS
APFIGADQAWKSGYTGKGIKVAVIDTGVDYTHPDLKNNFGPYKGYDFVDNDYDPQETPTGDPRGGATDHGTHVAGTIAAN
GQIKGVAPEATLLAYRVLGPGGSGTTENVIAGIEKAVADGAKVMNLSLGNSLNSPDYATSIALDWAMAEGVVAVTSNGNS
GPENWTVGSPGTSRVAISVGASQLPYNEYSVTLPSYSSAKVMGYQEEKDLEALNGQEVELVEAGLGQADDFSGKDVKGKV
AVIQRGVIPFVDKAENAKNAGAIGAVIYNNATGEIEANVMGMAVPTVKLSKEEGEKLVQQIKEGKHSVVFSFKLDKKLGE
TIASFSSRGPVMDTWMIKPDVSAPGVNIVSTIPTHDPKNPYGYGSKQGTSMASPHVAGTAAILKQAKPDWTPEQIKGVLM
NTAEKLTDENGKPLPHNTQGAGSIRIMEALKASSIVTPGSHSYGTFLKDKGKQTKKQAFTIENLSSHRKAYQLEYSFKGT
GITVSGTERVVVPANQTGKAAAKVTVNSAKTKAGTYEGTVYIREDGRKVAEIPLLLIVKEPDYPRVTSVTVEPGAKQGAY
TIEAYLPGGAEELAFLVYDENLNLLGQAGVYKNQGKGYQSYQWNGKINDAASLKSGKYYMLAYASAKGKSSYVLTEDPFI
VE
>Mature_802_residues
MRKSIVRYFVMAFILLFALSTFLTGVQATSVPDKKSPELEKAEIYGDIDVTSDKQTTVIVELKEKSLAEAKADGEKQTKA
SLKTARSKALKTLKKAKVNREYDRVFSGFSMKLPASEIPKLLAVKEVKAVYPNATYKPDSVKGKDVTLAADAIYPQMDKS
APFIGADQAWKSGYTGKGIKVAVIDTGVDYTHPDLKNNFGPYKGYDFVDNDYDPQETPTGDPRGGATDHGTHVAGTIAAN
GQIKGVAPEATLLAYRVLGPGGSGTTENVIAGIEKAVADGAKVMNLSLGNSLNSPDYATSIALDWAMAEGVVAVTSNGNS
GPENWTVGSPGTSRVAISVGASQLPYNEYSVTLPSYSSAKVMGYQEEKDLEALNGQEVELVEAGLGQADDFSGKDVKGKV
AVIQRGVIPFVDKAENAKNAGAIGAVIYNNATGEIEANVMGMAVPTVKLSKEEGEKLVQQIKEGKHSVVFSFKLDKKLGE
TIASFSSRGPVMDTWMIKPDVSAPGVNIVSTIPTHDPKNPYGYGSKQGTSMASPHVAGTAAILKQAKPDWTPEQIKGVLM
NTAEKLTDENGKPLPHNTQGAGSIRIMEALKASSIVTPGSHSYGTFLKDKGKQTKKQAFTIENLSSHRKAYQLEYSFKGT
GITVSGTERVVVPANQTGKAAAKVTVNSAKTKAGTYEGTVYIREDGRKVAEIPLLLIVKEPDYPRVTSVTVEPGAKQGAY
TIEAYLPGGAEELAFLVYDENLNLLGQAGVYKNQGKGYQSYQWNGKINDAASLKSGKYYMLAYASAKGKSSYVLTEDPFI
VE

Specific function: Not required for growth or sporulation [H]

COG id: COG1404

COG function: function code O; Subtilisin-like serine proteases

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S8 family [H]

Homologues:

Organism=Homo sapiens, GI4506775, Length=180, Percent_Identity=32.7777777777778, Blast_Score=80, Evalue=9e-15,
Organism=Homo sapiens, GI4505577, Length=97, Percent_Identity=41.2371134020619, Blast_Score=72, Evalue=2e-12,
Organism=Homo sapiens, GI20336180, Length=97, Percent_Identity=41.2371134020619, Blast_Score=72, Evalue=2e-12,
Organism=Homo sapiens, GI20336182, Length=97, Percent_Identity=41.2371134020619, Blast_Score=72, Evalue=3e-12,
Organism=Homo sapiens, GI27894285, Length=97, Percent_Identity=41.2371134020619, Blast_Score=71, Evalue=3e-12,
Organism=Homo sapiens, GI20336190, Length=97, Percent_Identity=41.2371134020619, Blast_Score=71, Evalue=3e-12,
Organism=Homo sapiens, GI20336184, Length=97, Percent_Identity=41.2371134020619, Blast_Score=71, Evalue=4e-12,
Organism=Homo sapiens, GI20336188, Length=97, Percent_Identity=41.2371134020619, Blast_Score=71, Evalue=4e-12,
Organism=Homo sapiens, GI76443679, Length=118, Percent_Identity=40.6779661016949, Blast_Score=70, Evalue=6e-12,
Organism=Homo sapiens, GI20336186, Length=97, Percent_Identity=41.2371134020619, Blast_Score=70, Evalue=8e-12,
Organism=Homo sapiens, GI20336244, Length=81, Percent_Identity=44.4444444444444, Blast_Score=70, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI71987206, Length=99, Percent_Identity=42.4242424242424, Blast_Score=70, Evalue=4e-12,
Organism=Saccharomyces cerevisiae, GI6319893, Length=244, Percent_Identity=29.5081967213115, Blast_Score=74, Evalue=6e-14,
Organism=Saccharomyces cerevisiae, GI6320775, Length=181, Percent_Identity=33.1491712707182, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI45550681, Length=184, Percent_Identity=29.8913043478261, Blast_Score=83, Evalue=6e-16,
Organism=Drosophila melanogaster, GI281360987, Length=94, Percent_Identity=40.4255319148936, Blast_Score=70, Evalue=6e-12,
Organism=Drosophila melanogaster, GI24642488, Length=94, Percent_Identity=40.4255319148936, Blast_Score=70, Evalue=6e-12,
Organism=Drosophila melanogaster, GI24642484, Length=94, Percent_Identity=40.4255319148936, Blast_Score=70, Evalue=6e-12,
Organism=Drosophila melanogaster, GI24642486, Length=94, Percent_Identity=40.4255319148936, Blast_Score=70, Evalue=6e-12,
Organism=Drosophila melanogaster, GI24642494, Length=94, Percent_Identity=40.4255319148936, Blast_Score=70, Evalue=6e-12,
Organism=Drosophila melanogaster, GI24642490, Length=94, Percent_Identity=40.4255319148936, Blast_Score=70, Evalue=6e-12,
Organism=Drosophila melanogaster, GI45555723, Length=94, Percent_Identity=40.4255319148936, Blast_Score=70, Evalue=6e-12,
Organism=Drosophila melanogaster, GI24642492, Length=94, Percent_Identity=40.4255319148936, Blast_Score=70, Evalue=6e-12,
Organism=Drosophila melanogaster, GI281360985, Length=94, Percent_Identity=40.4255319148936, Blast_Score=69, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000209
- InterPro:   IPR022398
- InterPro:   IPR015500
- InterPro:   IPR010259
- InterPro:   IPR003137 [H]

Pfam domain/function: PF05922 Inhibitor_I9; PF02225 PA; PF00082 Peptidase_S8 [H]

EC number: NA

Molecular weight: Translated: 85627; Mature: 85627

Theoretical pI: Translated: 8.94; Mature: 8.94

Prosite motif: PS00136 SUBTILASE_ASP ; PS00137 SUBTILASE_HIS ; PS00138 SUBTILASE_SER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKSIVRYFVMAFILLFALSTFLTGVQATSVPDKKSPELEKAEIYGDIDVTSDKQTTVIV
CCHHHHHHHHHHHHHHHHHHHHHHCCEECCCCCCCCCCCCCEEEEECEEECCCCCEEEEE
ELKEKSLAEAKADGEKQTKASLKTARSKALKTLKKAKVNREYDRVFSGFSMKLPASEIPK
EECCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCEEECCHHHCCH
LLAVKEVKAVYPNATYKPDSVKGKDVTLAADAIYPQMDKSAPFIGADQAWKSGYTGKGIK
HHHHHHHHHHCCCCCCCCCCCCCCEEEEEEHHHCCCCCCCCCCCCCCHHHHCCCCCCCEE
VAVIDTGVDYTHPDLKNNFGPYKGYDFVDNDYDPQETPTGDPRGGATDHGTHVAGTIAAN
EEEEECCCCCCCCCHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEEC
GQIKGVAPEATLLAYRVLGPGGSGTTENVIAGIEKAVADGAKVMNLSLGNSLNSPDYATS
CEEEECCCCCEEEEEEEECCCCCCCHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCEE
IALDWAMAEGVVAVTSNGNSGPENWTVGSPGTSRVAISVGASQLPYNEYSVTLPSYSSAK
EEEEEHHHCCEEEEECCCCCCCCCEECCCCCCCEEEEEECCCCCCCCCEEEECCCCCCCE
VMGYQEEKDLEALNGQEVELVEAGLGQADDFSGKDVKGKVAVIQRGVIPFVDKAENAKNA
EECCCCHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCC
GAIGAVIYNNATGEIEANVMGMAVPTVKLSKEEGEKLVQQIKEGKHSVVFSFKLDKKLGE
CCEEEEEEECCCCEEEEEEEEEEECEEEECHHHHHHHHHHHHCCCCEEEEEEEECHHHHH
TIASFSSRGPVMDTWMIKPDVSAPGVNIVSTIPTHDPKNPYGYGSKQGTSMASPHVAGTA
HHHHHHCCCCCEEEEEECCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCHHHH
AILKQAKPDWTPEQIKGVLMNTAEKLTDENGKPLPHNTQGAGSIRIMEALKASSIVTPGS
HHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHCCEECCCC
HSYGTFLKDKGKQTKKQAFTIENLSSHRKAYQLEYSFKGTGITVSGTERVVVPANQTGKA
CCCCCHHHHCCCHHHHHHEEHHHHHCCCEEEEEEEEECCCCEEECCCCEEEECCCCCCCE
AAKVTVNSAKTKAGTYEGTVYIREDGRKVAEIPLLLIVKEPDYPRVTSVTVEPGAKQGAY
EEEEEECCCCCCCCCEEEEEEEECCCCEEEECCEEEEEECCCCCCEEEEEECCCCCCCCE
TIEAYLPGGAEELAFLVYDENLNLLGQAGVYKNQGKGYQSYQWNGKINDAASLKSGKYYM
EEEEECCCCHHHEEEEEEECCCCEEECCCCCCCCCCCCCEEECCCCCCCHHHCCCCCEEE
LAYASAKGKSSYVLTEDPFIVE
EEEEECCCCCCEEEECCCEEEC
>Mature Secondary Structure
MRKSIVRYFVMAFILLFALSTFLTGVQATSVPDKKSPELEKAEIYGDIDVTSDKQTTVIV
CCHHHHHHHHHHHHHHHHHHHHHHCCEECCCCCCCCCCCCCEEEEECEEECCCCCEEEEE
ELKEKSLAEAKADGEKQTKASLKTARSKALKTLKKAKVNREYDRVFSGFSMKLPASEIPK
EECCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCEEECCHHHCCH
LLAVKEVKAVYPNATYKPDSVKGKDVTLAADAIYPQMDKSAPFIGADQAWKSGYTGKGIK
HHHHHHHHHHCCCCCCCCCCCCCCEEEEEEHHHCCCCCCCCCCCCCCHHHHCCCCCCCEE
VAVIDTGVDYTHPDLKNNFGPYKGYDFVDNDYDPQETPTGDPRGGATDHGTHVAGTIAAN
EEEEECCCCCCCCCHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEEC
GQIKGVAPEATLLAYRVLGPGGSGTTENVIAGIEKAVADGAKVMNLSLGNSLNSPDYATS
CEEEECCCCCEEEEEEEECCCCCCCHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCEE
IALDWAMAEGVVAVTSNGNSGPENWTVGSPGTSRVAISVGASQLPYNEYSVTLPSYSSAK
EEEEEHHHCCEEEEECCCCCCCCCEECCCCCCCEEEEEECCCCCCCCCEEEECCCCCCCE
VMGYQEEKDLEALNGQEVELVEAGLGQADDFSGKDVKGKVAVIQRGVIPFVDKAENAKNA
EECCCCHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCC
GAIGAVIYNNATGEIEANVMGMAVPTVKLSKEEGEKLVQQIKEGKHSVVFSFKLDKKLGE
CCEEEEEEECCCCEEEEEEEEEEECEEEECHHHHHHHHHHHHCCCCEEEEEEEECHHHHH
TIASFSSRGPVMDTWMIKPDVSAPGVNIVSTIPTHDPKNPYGYGSKQGTSMASPHVAGTA
HHHHHHCCCCCEEEEEECCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCHHHH
AILKQAKPDWTPEQIKGVLMNTAEKLTDENGKPLPHNTQGAGSIRIMEALKASSIVTPGS
HHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHCCEECCCC
HSYGTFLKDKGKQTKKQAFTIENLSSHRKAYQLEYSFKGTGITVSGTERVVVPANQTGKA
CCCCCHHHHCCCHHHHHHEEHHHHHCCCEEEEEEEEECCCCEEECCCCEEEECCCCCCCE
AAKVTVNSAKTKAGTYEGTVYIREDGRKVAEIPLLLIVKEPDYPRVTSVTVEPGAKQGAY
EEEEEECCCCCCCCCEEEEEEEECCCCEEEECCEEEEEECCCCCCEEEEEECCCCCCCCE
TIEAYLPGGAEELAFLVYDENLNLLGQAGVYKNQGKGYQSYQWNGKINDAASLKSGKYYM
EEEEECCCCHHHEEEEEEECCCCEEECCCCCCCCCCCCCEEECCCCCCCHHHCCCCCEEE
LAYASAKGKSSYVLTEDPFIVE
EEEEECCCCCCEEEECCCEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1938892; 7934828; 9384377; 10658653 [H]