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The map label for this gene is hpcB [H]

Identifier: 52787668

GI number: 52787668

Start: 3815812

End: 3816663

Strand: Reverse

Name: hpcB [H]

Synonym: BLi03991

Alternate gene names: 52787668

Gene position: 3816663-3815812 (Counterclockwise)

Preceding gene: 52787669

Following gene: 52787667

Centisome position: 90.39

GC content: 51.76

Gene sequence:

>852_bases
ATGTCAATCGAATTGGCGGCGCTTGTTCCGCATACACCGAGGATGTGTTTTGAAGATAAAACCCCTGACTTCCAAAGAGA
GCTGGTCAAGGGCATGAAGAGGCTCTCCAGGATTATTGAAAGAATTGAGCCCGATGCCGTTGTCCTGATTTCCTGTCACT
GGACGTCAAGCTTTGACCATCTGATCGATGCAGCTCCCGACCATCAAGGCGTTTTAACGGCTTTGGAGTGTCCGAATTTA
ATTTCCGATGTTCCGTATTCTTACCCCGGGGACACTGAATTGGCGCTGCAATTGGCTGAAGCCGGCAGAGAAGGGGGGCT
TTCCGTCATTCCTGTCAATGATCCAGCTTACTGCTGGGATTACGGGACGGTCGTTCCGCTGCGCTACCTCGTTCCAAAGG
GAGATATTCCGGTTATCGATTTATCGGTTACATTGGCCGCGAACCTGGAAGAAACGCATTTGTGGGGCCGGCTTGCCGGA
AGAGTGCTGAAAGAAAGCAGAAAGAAAACCGTGTTCATCAGCAGCGGGGCGCTAAGCCATCATTTGGTGAGGGGGCCGGA
ATGTATGCCGACATTGGCCGAACAGGCCCTCGATGCACAATTTTTGACCTACTTAACAGACAACGATCTTTTATCAGCTC
AGCAGATGCTGCCTCAATATGCTAAAAACGCCGGGCTTGAAGCCGGCGGCCGCCACATTGCAATGCTATTGGGCGTGCTG
GAGGACGGATGTAAAAGCACGTTTTACGGATACGGTCAGTCTTCCGGGAGCTCCAATGTCGTCATGGCATTCGAGCCGGC
GGGACAAAAAGCTCGCACGCACGCTTTCAATGAAAAAGATACCGTGCGTTAA

Upstream 100 bases:

>100_bases
TCCGCGTTCTTGTCACCGAAGTTTCTAAAAGCCACTGGGGCATAGGCGGCACACCGGTCTCAAAATTAAGACCTTAAAGA
AGGCGATGGGAGGAATCTAC

Downstream 100 bases:

>100_bases
GCTGCTTTCATAATACGATAAGAATCGTGGAGGGGAACATGAAAAATCGTTCAGTTCATCCAGCGGAAGTCATGGCGGCC
AGCAAATTTAACAAAGTGCA

Product: hypothetical protein

Products: NA

Alternate protein names: Homoprotocatechuate 2,3-dioxygenase; HPC dioxygenase [H]

Number of amino acids: Translated: 283; Mature: 282

Protein sequence:

>283_residues
MSIELAALVPHTPRMCFEDKTPDFQRELVKGMKRLSRIIERIEPDAVVLISCHWTSSFDHLIDAAPDHQGVLTALECPNL
ISDVPYSYPGDTELALQLAEAGREGGLSVIPVNDPAYCWDYGTVVPLRYLVPKGDIPVIDLSVTLAANLEETHLWGRLAG
RVLKESRKKTVFISSGALSHHLVRGPECMPTLAEQALDAQFLTYLTDNDLLSAQQMLPQYAKNAGLEAGGRHIAMLLGVL
EDGCKSTFYGYGQSSGSSNVVMAFEPAGQKARTHAFNEKDTVR

Sequences:

>Translated_283_residues
MSIELAALVPHTPRMCFEDKTPDFQRELVKGMKRLSRIIERIEPDAVVLISCHWTSSFDHLIDAAPDHQGVLTALECPNL
ISDVPYSYPGDTELALQLAEAGREGGLSVIPVNDPAYCWDYGTVVPLRYLVPKGDIPVIDLSVTLAANLEETHLWGRLAG
RVLKESRKKTVFISSGALSHHLVRGPECMPTLAEQALDAQFLTYLTDNDLLSAQQMLPQYAKNAGLEAGGRHIAMLLGVL
EDGCKSTFYGYGQSSGSSNVVMAFEPAGQKARTHAFNEKDTVR
>Mature_282_residues
SIELAALVPHTPRMCFEDKTPDFQRELVKGMKRLSRIIERIEPDAVVLISCHWTSSFDHLIDAAPDHQGVLTALECPNLI
SDVPYSYPGDTELALQLAEAGREGGLSVIPVNDPAYCWDYGTVVPLRYLVPKGDIPVIDLSVTLAANLEETHLWGRLAGR
VLKESRKKTVFISSGALSHHLVRGPECMPTLAEQALDAQFLTYLTDNDLLSAQQMLPQYAKNAGLEAGGRHIAMLLGVLE
DGCKSTFYGYGQSSGSSNVVMAFEPAGQKARTHAFNEKDTVR

Specific function: Transforms homoprotocatechuic acid (HPC) into 5- carboxymethyl-2-hydroxy-muconic semialdehyde (CHMS) [H]

COG id: COG3384

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011984
- InterPro:   IPR004183 [H]

Pfam domain/function: PF02900 LigB [H]

EC number: =1.13.11.15 [H]

Molecular weight: Translated: 31008; Mature: 30877

Theoretical pI: Translated: 5.34; Mature: 5.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIELAALVPHTPRMCFEDKTPDFQRELVKGMKRLSRIIERIEPDAVVLISCHWTSSFDH
CCEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCHHH
LIDAAPDHQGVLTALECPNLISDVPYSYPGDTELALQLAEAGREGGLSVIPVNDPAYCWD
HHHCCCCCCCCEEEHHCCHHHHHCCCCCCCCHHHHHHHHHCCCCCCEEEEECCCCCEEEC
YGTVVPLRYLVPKGDIPVIDLSVTLAANLEETHLWGRLAGRVLKESRKKTVFISSGALSH
CCCCCCHHEECCCCCCCEEEEEEEEECCCHHHHHHHHHHHHHHHHCCCCEEEEECCCHHH
HLVRGPECMPTLAEQALDAQFLTYLTDNDLLSAQQMLPQYAKNAGLEAGGRHIAMLLGVL
HHHCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHH
EDGCKSTFYGYGQSSGSSNVVMAFEPAGQKARTHAFNEKDTVR
HHHHHHHCCCCCCCCCCCCEEEEECCCCCCHHHHCCCCCCCCC
>Mature Secondary Structure 
SIELAALVPHTPRMCFEDKTPDFQRELVKGMKRLSRIIERIEPDAVVLISCHWTSSFDH
CEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCHHH
LIDAAPDHQGVLTALECPNLISDVPYSYPGDTELALQLAEAGREGGLSVIPVNDPAYCWD
HHHCCCCCCCCEEEHHCCHHHHHCCCCCCCCHHHHHHHHHCCCCCCEEEEECCCCCEEEC
YGTVVPLRYLVPKGDIPVIDLSVTLAANLEETHLWGRLAGRVLKESRKKTVFISSGALSH
CCCCCCHHEECCCCCCCEEEEEEEEECCCHHHHHHHHHHHHHHHHCCCCEEEEECCCHHH
HLVRGPECMPTLAEQALDAQFLTYLTDNDLLSAQQMLPQYAKNAGLEAGGRHIAMLLGVL
HHHCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHH
EDGCKSTFYGYGQSSGSSNVVMAFEPAGQKARTHAFNEKDTVR
HHHHHHHCCCCCCCCCCCCEEEEECCCCCCHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2261999 [H]