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The map label for this gene is murAB

Identifier: 52787636

GI number: 52787636

Start: 3782785

End: 3784074

Strand: Reverse

Name: murAB

Synonym: BLi03958

Alternate gene names: 52787636

Gene position: 3784074-3782785 (Counterclockwise)

Preceding gene: 52787637

Following gene: 52787635

Centisome position: 89.61

GC content: 51.24

Gene sequence:

>1290_bases
ATGGAAAAGTTAAATATAGCTGGCGGCGATCCTCTCAATGGCACAGTACATATAAGCGGAGCGAAAAACAGCGCTGTCGC
TCTCATACCTGCGACGATTTTGGCTGATTCGACGGTTACGCTTGAAGGCCTTCCCCATATTTCAGACATTTTGACGCTTC
GCGATCTGCTGAGAGAGATCGGCGGAAACGTTCACTTTGAAAAGGGAGAAATGGTCGTTGATCCTGCGCCGATGATCAGC
ATGCCTTTGCCGAATGGAAAAGTGAAACAGCTTCGGGCTTCTTATTACTTAATGGGCGCGATGCTAGGACGCTTTAAGAA
AGCGGTCATCGGCCTTCCAGGCGGCTGCCACCTTGGTCCGAGACCGATTGATCAGCATATCAAAGGTTTTGAGGCGCTCG
GAGCCGAAGTGACAAACGAACAGGGTGCGATCTATCTGCGTGCGGAGGAATTAAAAGGCGCGCGCATTTATCTTGATGTC
GTCAGTGTTGGAGCAACGATCAACATCATGCTTGCCGCCGTGCTTGCCAAAGGCAGAACCGTAATTGAAAACGCTGCGAA
AGAACCTGAGATTATCGATGTTGCCACTCTTTTAACAAGCATGGGAGCAAAAATAAAAGGCGCCGGTACGGACGTCATCC
GCATCGAAGGCGTTGAATCGCTTCACGGGTGCAGACACTCGATTATTCCGGACCGGATCGAAGCCGGCACTTTCATGATT
GCAGCTGCTTCCATGGGACAAGAAGTGCTGATTGATAATGTAATTCCGACGCATTTGGAATCGTTAATCGCCAAGCTCCG
CGAAATGGGGGTTCGAATCGAAGAAAGCAGCGAGCAGATTTTAATGGTCGGCGGACAGAAAGAGCTGAAACCGGTCGATT
TGAAAACGCTCGTATACCCCGGCTTTCCGACCGATCTGCAGCAGCCGATGACATCGCTTTTAACGAAGGCAAACGGGACG
AGCGTTGTCACTGACACCATTTACTCCGCTCGCTTCAAACATATTGACGAGCTGAGACGCATGGGTGCGTCGATGAAGGT
TGAAGGAAGATCGGCGATCATTACCGGGCCAGCTCCTTTGCAGGGCGCCAAGGTGAAAGCGAGTGATCTTCGGGCGGGAG
CATGTCTCGTTGTTGCCGGTCTAATGGCGGAAGGTGTCACGGAAATCACCGGTTTGGAGCACCTTGACAGAGGCTACAGT
CAGCTTGAAGAAAAGCTGACAAAGCTCGGGGCCACTGTCTGGCGCGAAAAATTGACAGACCAGGAAATTGAACAGCTGCA
AAACTCGTGA

Upstream 100 bases:

>100_bases
TAATTGGATAGATTTTGAAATGAACCATTTATTTTGAGTTTGAAGGAAATCTCATTATGAAGCGCTCCATTAGCTATCTT
CTTTAAGGAAGGAGACGATC

Downstream 100 bases:

>100_bases
TCGACAAATGCTGTTATAGATAAAACATAAAACGATTTCATATGGGTGAGAGGAGATTAGATAGGAATGGAAAGAAGCTT
ATCGATGGAACTTGTTCGTG

Product: UDP-N-acetylglucosamine 1-carboxyvinyltransferase

Products: NA

Alternate protein names: Enoylpyruvate transferase 2; UDP-N-acetylglucosamine enolpyruvyl transferase 2; EPT 2

Number of amino acids: Translated: 429; Mature: 429

Protein sequence:

>429_residues
MEKLNIAGGDPLNGTVHISGAKNSAVALIPATILADSTVTLEGLPHISDILTLRDLLREIGGNVHFEKGEMVVDPAPMIS
MPLPNGKVKQLRASYYLMGAMLGRFKKAVIGLPGGCHLGPRPIDQHIKGFEALGAEVTNEQGAIYLRAEELKGARIYLDV
VSVGATINIMLAAVLAKGRTVIENAAKEPEIIDVATLLTSMGAKIKGAGTDVIRIEGVESLHGCRHSIIPDRIEAGTFMI
AAASMGQEVLIDNVIPTHLESLIAKLREMGVRIEESSEQILMVGGQKELKPVDLKTLVYPGFPTDLQQPMTSLLTKANGT
SVVTDTIYSARFKHIDELRRMGASMKVEGRSAIITGPAPLQGAKVKASDLRAGACLVVAGLMAEGVTEITGLEHLDRGYS
QLEEKLTKLGATVWREKLTDQEIEQLQNS

Sequences:

>Translated_429_residues
MEKLNIAGGDPLNGTVHISGAKNSAVALIPATILADSTVTLEGLPHISDILTLRDLLREIGGNVHFEKGEMVVDPAPMIS
MPLPNGKVKQLRASYYLMGAMLGRFKKAVIGLPGGCHLGPRPIDQHIKGFEALGAEVTNEQGAIYLRAEELKGARIYLDV
VSVGATINIMLAAVLAKGRTVIENAAKEPEIIDVATLLTSMGAKIKGAGTDVIRIEGVESLHGCRHSIIPDRIEAGTFMI
AAASMGQEVLIDNVIPTHLESLIAKLREMGVRIEESSEQILMVGGQKELKPVDLKTLVYPGFPTDLQQPMTSLLTKANGT
SVVTDTIYSARFKHIDELRRMGASMKVEGRSAIITGPAPLQGAKVKASDLRAGACLVVAGLMAEGVTEITGLEHLDRGYS
QLEEKLTKLGATVWREKLTDQEIEQLQNS
>Mature_429_residues
MEKLNIAGGDPLNGTVHISGAKNSAVALIPATILADSTVTLEGLPHISDILTLRDLLREIGGNVHFEKGEMVVDPAPMIS
MPLPNGKVKQLRASYYLMGAMLGRFKKAVIGLPGGCHLGPRPIDQHIKGFEALGAEVTNEQGAIYLRAEELKGARIYLDV
VSVGATINIMLAAVLAKGRTVIENAAKEPEIIDVATLLTSMGAKIKGAGTDVIRIEGVESLHGCRHSIIPDRIEAGTFMI
AAASMGQEVLIDNVIPTHLESLIAKLREMGVRIEESSEQILMVGGQKELKPVDLKTLVYPGFPTDLQQPMTSLLTKANGT
SVVTDTIYSARFKHIDELRRMGASMKVEGRSAIITGPAPLQGAKVKASDLRAGACLVVAGLMAEGVTEITGLEHLDRGYS
QLEEKLTKLGATVWREKLTDQEIEQLQNS

Specific function: Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine

COG id: COG0766

COG function: function code M; UDP-N-acetylglucosamine enolpyruvyl transferase

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EPSP synthase family. MurA subfamily

Homologues:

Organism=Escherichia coli, GI1789580, Length=420, Percent_Identity=44.047619047619, Blast_Score=340, Evalue=8e-95,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MURA2_BACLD (Q65DU2)

Other databases:

- EMBL:   AE017333
- EMBL:   CP000002
- RefSeq:   YP_081035.1
- RefSeq:   YP_093465.1
- ProteinModelPortal:   Q65DU2
- SMR:   Q65DU2
- STRING:   Q65DU2
- EnsemblBacteria:   EBBACT00000057554
- EnsemblBacteria:   EBBACT00000058654
- GeneID:   3027647
- GeneID:   3101351
- GenomeReviews:   AE017333_GR
- GenomeReviews:   CP000002_GR
- KEGG:   bld:BLi03958
- KEGG:   bli:BL03971
- NMPDR:   fig|279010.5.peg.4095
- eggNOG:   COG0766
- GeneTree:   EBGT00050000001036
- HOGENOM:   HBG482701
- OMA:   IGGKVTY
- ProtClustDB:   PRK12830
- BioCyc:   BLIC279010-1:BLI03958-MONOMER
- BioCyc:   BLIC279010:BL03971-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00111
- InterPro:   IPR001986
- InterPro:   IPR013792
- InterPro:   IPR005750
- Gene3D:   G3DSA:3.65.10.10
- PANTHER:   PTHR21090:SF4
- TIGRFAMs:   TIGR01072

Pfam domain/function: PF00275 EPSP_synthase; SSF55205 RNA3'_cycl/enolpyr_transf_A/B

EC number: =2.5.1.7

Molecular weight: Translated: 45927; Mature: 45927

Theoretical pI: Translated: 6.36; Mature: 6.36

Prosite motif: NA

Important sites: ACT_SITE 116-116

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEKLNIAGGDPLNGTVHISGAKNSAVALIPATILADSTVTLEGLPHISDILTLRDLLREI
CCCCCCCCCCCCCCEEEEECCCCCEEEEEEHHHHCCCEEEECCCCHHHHHHHHHHHHHHH
GGNVHFEKGEMVVDPAPMISMPLPNGKVKQLRASYYLMGAMLGRFKKAVIGLPGGCHLGP
CCCEEEECCCEEECCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
RPIDQHIKGFEALGAEVTNEQGAIYLRAEELKGARIYLDVVSVGATINIMLAAVLAKGRT
CCHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCCEEEEEEEHHCCHHHHHHHHHHHCCCH
VIENAAKEPEIIDVATLLTSMGAKIKGAGTDVIRIEGVESLHGCRHSIIPDRIEAGTFMI
HHHHCCCCCCHHHHHHHHHHCCCEEECCCCCEEEECCCHHHHHHHHHCCCCCCCCCEEEE
AAASMGQEVLIDNVIPTHLESLIAKLREMGVRIEESSEQILMVGGQKELKPVDLKTLVYP
EEHHCCCHHHHHCCCHHHHHHHHHHHHHHCCEEECCCCEEEEECCCCCCCCCCEEEEEEC
GFPTDLQQPMTSLLTKANGTSVVTDTIYSARFKHIDELRRMGASMKVEGRSAIITGPAPL
CCCHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHCCCCEEECCCEEEEECCCCC
QGAKVKASDLRAGACLVVAGLMAEGVTEITGLEHLDRGYSQLEEKLTKLGATVWREKLTD
CCCEEEHHHCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
QEIEQLQNS
HHHHHHHCC
>Mature Secondary Structure
MEKLNIAGGDPLNGTVHISGAKNSAVALIPATILADSTVTLEGLPHISDILTLRDLLREI
CCCCCCCCCCCCCCEEEEECCCCCEEEEEEHHHHCCCEEEECCCCHHHHHHHHHHHHHHH
GGNVHFEKGEMVVDPAPMISMPLPNGKVKQLRASYYLMGAMLGRFKKAVIGLPGGCHLGP
CCCEEEECCCEEECCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
RPIDQHIKGFEALGAEVTNEQGAIYLRAEELKGARIYLDVVSVGATINIMLAAVLAKGRT
CCHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCCEEEEEEEHHCCHHHHHHHHHHHCCCH
VIENAAKEPEIIDVATLLTSMGAKIKGAGTDVIRIEGVESLHGCRHSIIPDRIEAGTFMI
HHHHCCCCCCHHHHHHHHHHCCCEEECCCCCEEEECCCHHHHHHHHHCCCCCCCCCEEEE
AAASMGQEVLIDNVIPTHLESLIAKLREMGVRIEESSEQILMVGGQKELKPVDLKTLVYP
EEHHCCCHHHHHCCCHHHHHHHHHHHHHHCCEEECCCCEEEEECCCCCCCCCCEEEEEEC
GFPTDLQQPMTSLLTKANGTSVVTDTIYSARFKHIDELRRMGASMKVEGRSAIITGPAPL
CCCHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHCCCCEEECCCEEEEECCCCC
QGAKVKASDLRAGACLVVAGLMAEGVTEITGLEHLDRGYSQLEEKLTKLGATVWREKLTD
CCCEEEHHHCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
QEIEQLQNS
HHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA