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The map label for this gene is murAA

Identifier: 52787600

GI number: 52787600

Start: 3749143

End: 3750453

Strand: Reverse

Name: murAA

Synonym: BLi03922

Alternate gene names: 52787600

Gene position: 3750453-3749143 (Counterclockwise)

Preceding gene: 52787601

Following gene: 52787599

Centisome position: 88.82

GC content: 46.38

Gene sequence:

>1311_bases
TTGGAAAAAATCATCGTCCGCGGCGGTCGAAAGTTAAACGGCACAGTCAAAGTTGAAGGAGCAAAAAATGCCGTTTTACC
AGTTATCGCTGCATCTTTATTAGCCAGTGAAGAAAAAAGCGTAATATGTGATGTGCCTACGCTCTCCGATGTATATACGA
TTAACGAAGTGTTACGTCATTTAGGCGCAAGTGTACATTTTGAAAATAATACAGTAACGGTTGATGCATCTCGCACTTTG
TCTACGGAAGCTCCGTTCGAATATGTTCGTAAAATGCGCGCATCCGTATTGGTGATGGGTCCGCTTCTTGCTCGCACAGG
CCATTCGAGAGTGGCTTTGCCTGGAGGATGTGCAATCGGTTCAAGACCGATCGATCAGCATCTGAAAGGCTTTGAAGCAA
TGGGGGCAAAAATTAAGGTCGGAAACGGCTTTATTGAAGCGACTGTAGAAGGCCGCCTTCAAGGAGCGAAAATTTACCTT
GATTTCCCTAGTGTCGGAGCAACTGAAAACCTGATTATGGCTGCAGCTTTGGCTGAGGGCACGACAACTCTCGAAAATGC
TGCTAAAGAGCCTGAAATCGTTGATCTGGCTAACTATATCAATGCAATGGGCGGTAAAATTCGGGGTGCCGGTACAGGCA
CCATTAAAATTGAAGGCGTTAAGGCGCTTCATGGGGCAAAACATACGATTATTCCTGACCGGATAGAGGCGGGAACGTTC
ATGGTTGCCGCGGCGATTACCGAAGGGAACGTACTGGTAAAGGGAGCGGTTCCTGAGCACTTAACATCTTTAATTGCGAA
AATGGAAGAAATGGGCGTTCAAATCTTGGAAGAAGGAGACGGTCTTCGGATCATCGGTCCTTCTGAATTGAAGCCTATTG
ATTTAAAAACAATGCCACATCCAGGTTTCCCGACTGATATGCAGTCACAGATGATGGCTCTTTTGATGCGCGCAAATGGA
ACCAGCATGATCACAGAAACCGTCTTTGAGAACCGCTTCATGCACGCGGAAGAATTCCGCCGTATGAACGGAGATATTAA
AATCGAAGGCCGTTCTGTCATCATTAATGGTCCTGTGCAGCTTCAAGGCGCTGAAGTTGCCGCAACGGATCTTCGCGCCG
GCGCAGCTCTTATCCTTGCTGGCCTTGTTGCTGACGGTCATACACGCGTAACCGAATTAAAACATTTAGACCGTGGATAT
GTCAACTTCCACCAAAAACTTGCCGGTCTCGGCGCTGATATTGAGCGCGTTAACGATGAAGAAGCAGTTCATATTGAAAA
TAAAGAAGTTGTATCCGATTTAAATGCATAA

Upstream 100 bases:

>100_bases
GAAATGCGGGAATGGGCGAAAAACTTACCGTCACGGTTGGCACACCAATCGTCACGACTGAATATTAATATAGAGAAATT
GGGACGCGGAGGGGAATACC

Downstream 100 bases:

>100_bases
ATCAACTTGAAATCAGTATGTCATACGGCATACTGATTTTTGCGTTTCAAGTATTCTATATCAGTATGCCTCCCATATCT
ATCATTATGCACAAGAATTG

Product: UDP-N-acetylglucosamine 1-carboxyvinyltransferase

Products: NA

Alternate protein names: Enoylpyruvate transferase 1; UDP-N-acetylglucosamine enolpyruvyl transferase 1; EPT 1

Number of amino acids: Translated: 436; Mature: 436

Protein sequence:

>436_residues
MEKIIVRGGRKLNGTVKVEGAKNAVLPVIAASLLASEEKSVICDVPTLSDVYTINEVLRHLGASVHFENNTVTVDASRTL
STEAPFEYVRKMRASVLVMGPLLARTGHSRVALPGGCAIGSRPIDQHLKGFEAMGAKIKVGNGFIEATVEGRLQGAKIYL
DFPSVGATENLIMAAALAEGTTTLENAAKEPEIVDLANYINAMGGKIRGAGTGTIKIEGVKALHGAKHTIIPDRIEAGTF
MVAAAITEGNVLVKGAVPEHLTSLIAKMEEMGVQILEEGDGLRIIGPSELKPIDLKTMPHPGFPTDMQSQMMALLMRANG
TSMITETVFENRFMHAEEFRRMNGDIKIEGRSVIINGPVQLQGAEVAATDLRAGAALILAGLVADGHTRVTELKHLDRGY
VNFHQKLAGLGADIERVNDEEAVHIENKEVVSDLNA

Sequences:

>Translated_436_residues
MEKIIVRGGRKLNGTVKVEGAKNAVLPVIAASLLASEEKSVICDVPTLSDVYTINEVLRHLGASVHFENNTVTVDASRTL
STEAPFEYVRKMRASVLVMGPLLARTGHSRVALPGGCAIGSRPIDQHLKGFEAMGAKIKVGNGFIEATVEGRLQGAKIYL
DFPSVGATENLIMAAALAEGTTTLENAAKEPEIVDLANYINAMGGKIRGAGTGTIKIEGVKALHGAKHTIIPDRIEAGTF
MVAAAITEGNVLVKGAVPEHLTSLIAKMEEMGVQILEEGDGLRIIGPSELKPIDLKTMPHPGFPTDMQSQMMALLMRANG
TSMITETVFENRFMHAEEFRRMNGDIKIEGRSVIINGPVQLQGAEVAATDLRAGAALILAGLVADGHTRVTELKHLDRGY
VNFHQKLAGLGADIERVNDEEAVHIENKEVVSDLNA
>Mature_436_residues
MEKIIVRGGRKLNGTVKVEGAKNAVLPVIAASLLASEEKSVICDVPTLSDVYTINEVLRHLGASVHFENNTVTVDASRTL
STEAPFEYVRKMRASVLVMGPLLARTGHSRVALPGGCAIGSRPIDQHLKGFEAMGAKIKVGNGFIEATVEGRLQGAKIYL
DFPSVGATENLIMAAALAEGTTTLENAAKEPEIVDLANYINAMGGKIRGAGTGTIKIEGVKALHGAKHTIIPDRIEAGTF
MVAAAITEGNVLVKGAVPEHLTSLIAKMEEMGVQILEEGDGLRIIGPSELKPIDLKTMPHPGFPTDMQSQMMALLMRANG
TSMITETVFENRFMHAEEFRRMNGDIKIEGRSVIINGPVQLQGAEVAATDLRAGAALILAGLVADGHTRVTELKHLDRGY
VNFHQKLAGLGADIERVNDEEAVHIENKEVVSDLNA

Specific function: Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine

COG id: COG0766

COG function: function code M; UDP-N-acetylglucosamine enolpyruvyl transferase

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EPSP synthase family. MurA subfamily

Homologues:

Organism=Escherichia coli, GI1789580, Length=422, Percent_Identity=49.5260663507109, Blast_Score=395, Evalue=1e-111,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MURA1_BACLD (Q65DX8)

Other databases:

- EMBL:   AE017333
- EMBL:   CP000002
- RefSeq:   YP_081000.1
- RefSeq:   YP_093429.1
- ProteinModelPortal:   Q65DX8
- SMR:   Q65DX8
- STRING:   Q65DX8
- EnsemblBacteria:   EBBACT00000057464
- EnsemblBacteria:   EBBACT00000060924
- GeneID:   3028118
- GeneID:   3101237
- GenomeReviews:   AE017333_GR
- GenomeReviews:   CP000002_GR
- KEGG:   bld:BLi03922
- KEGG:   bli:BL04004
- NMPDR:   fig|279010.5.peg.4007
- eggNOG:   COG0766
- GeneTree:   EBGT00050000001036
- HOGENOM:   HBG482701
- OMA:   NRFMHLE
- ProtClustDB:   PRK09369
- BioCyc:   BLIC279010-1:BLI03922-MONOMER
- BioCyc:   BLIC279010:BL04004-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00111
- InterPro:   IPR001986
- InterPro:   IPR013792
- InterPro:   IPR005750
- Gene3D:   G3DSA:3.65.10.10
- PANTHER:   PTHR21090:SF4
- TIGRFAMs:   TIGR01072

Pfam domain/function: PF00275 EPSP_synthase; SSF55205 RNA3'_cycl/enolpyr_transf_A/B

EC number: =2.5.1.7

Molecular weight: Translated: 46556; Mature: 46556

Theoretical pI: Translated: 6.20; Mature: 6.20

Prosite motif: PS00430 TONB_DEPENDENT_REC_1

Important sites: ACT_SITE 117-117

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEKIIVRGGRKLNGTVKVEGAKNAVLPVIAASLLASEEKSVICDVPTLSDVYTINEVLRH
CCCEEEECCCEECCEEEECCCCCCHHHHHHHHHHHCCCCCEEECCCCCHHHHHHHHHHHH
LGASVHFENNTVTVDASRTLSTEAPFEYVRKMRASVLVMGPLLARTGHSRVALPGGCAIG
CCCEEEECCCEEEEECCCCCCCCCCHHHHHHHHHHEEEECHHHHCCCCCEEECCCCCCCC
SRPIDQHLKGFEAMGAKIKVGNGFIEATVEGRLQGAKIYLDFPSVGATENLIMAAALAEG
CCCHHHHHHHHHHCCCEEEECCCEEEEEEECCCCCEEEEEECCCCCCCHHHHEEEHHHCC
TTTLENAAKEPEIVDLANYINAMGGKIRGAGTGTIKIEGVKALHGAKHTIIPDRIEAGTF
CHHHHHHCCCCCHHHHHHHHHHCCCCEECCCCCEEEEECCHHHCCCCCCCCCCCCCCCEE
MVAAAITEGNVLVKGAVPEHLTSLIAKMEEMGVQILEEGDGLRIIGPSELKPIDLKTMPH
EEEEEEECCCEEEECCCHHHHHHHHHHHHHCCHHEEECCCCEEEECCCCCCCEEEECCCC
PGFPTDMQSQMMALLMRANGTSMITETVFENRFMHAEEFRRMNGDIKIEGRSVIINGPVQ
CCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHCCCCHHHHHHCCCCEEECCCEEEEECCEE
LQGAEVAATDLRAGAALILAGLVADGHTRVTELKHLDRGYVNFHQKLAGLGADIERVNDE
ECCCEEEEHHHHCCHHHHHHHHHCCCCHHHHHHHHHCCHHHHHHHHHHHCCCCHHHCCCC
EAVHIENKEVVSDLNA
CEEEECCHHHHHHCCC
>Mature Secondary Structure
MEKIIVRGGRKLNGTVKVEGAKNAVLPVIAASLLASEEKSVICDVPTLSDVYTINEVLRH
CCCEEEECCCEECCEEEECCCCCCHHHHHHHHHHHCCCCCEEECCCCCHHHHHHHHHHHH
LGASVHFENNTVTVDASRTLSTEAPFEYVRKMRASVLVMGPLLARTGHSRVALPGGCAIG
CCCEEEECCCEEEEECCCCCCCCCCHHHHHHHHHHEEEECHHHHCCCCCEEECCCCCCCC
SRPIDQHLKGFEAMGAKIKVGNGFIEATVEGRLQGAKIYLDFPSVGATENLIMAAALAEG
CCCHHHHHHHHHHCCCEEEECCCEEEEEEECCCCCEEEEEECCCCCCCHHHHEEEHHHCC
TTTLENAAKEPEIVDLANYINAMGGKIRGAGTGTIKIEGVKALHGAKHTIIPDRIEAGTF
CHHHHHHCCCCCHHHHHHHHHHCCCCEECCCCCEEEEECCHHHCCCCCCCCCCCCCCCEE
MVAAAITEGNVLVKGAVPEHLTSLIAKMEEMGVQILEEGDGLRIIGPSELKPIDLKTMPH
EEEEEEECCCEEEECCCHHHHHHHHHHHHHCCHHEEECCCCEEEECCCCCCCEEEECCCC
PGFPTDMQSQMMALLMRANGTSMITETVFENRFMHAEEFRRMNGDIKIEGRSVIINGPVQ
CCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHCCCCHHHHHHCCCCEEECCCEEEEECCEE
LQGAEVAATDLRAGAALILAGLVADGHTRVTELKHLDRGYVNFHQKLAGLGADIERVNDE
ECCCEEEEHHHHCCHHHHHHHHHCCCCHHHHHHHHHCCHHHHHHHHHHHCCCCHHHCCCC
EAVHIENKEVVSDLNA
CEEEECCHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA