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The map label for this gene is oxlT [H]

Identifier: 52787595

GI number: 52787595

Start: 3742167

End: 3743429

Strand: Direct

Name: oxlT [H]

Synonym: BLi03917

Alternate gene names: 52787595

Gene position: 3742167-3743429 (Clockwise)

Preceding gene: 52787591

Following gene: 52787596

Centisome position: 88.62

GC content: 51.78

Gene sequence:

>1263_bases
ATGAAAAAAGCGAAAAACAGGTGGCTCATTGCTTTATGTGCTGTAGGCATTCATTTGTCAATCGGGTCGGTATACGCATG
GAGCGTCTTTACAAACCCGCTCGCTGAAACCTTCGGCTGGAGCCTCAGCCAGATCAGTCTGACGTTCAGCATCGCTATTT
TATTTCTCGGGCTTTCAGCCGCATTTTTGGGACACTTCGTCGAAAAACACGGCCCCAAAAAAGCAGGCATGCTCGCCGCA
CTTTTCTTCGGAGCTGGCGTGACGTTTTCCGGCTTCGCCGTTCAGATCGGCTCCCTTCCCCTGCTTTATTTGTTTTATGG
AGTCTTCGGAGGGATCGGACTCGGCGTCGGCTATATTACACCCGTATCTTCGCTTGTTAAATGGTTTCCTGACCGCCGCG
GCTTGGCCACAGGGCTTGCCATTATGGGCTTCGGATTTGCGGCTTTGATCAGCAGCCCGATCATGCAAAAGCTGATCTCA
GCGGTCGGTATAGCCAACACCTTTTTTATTCTCGGCATCTGCTACTTTCTTGTGATGATGCTCTCTTCGCTTTACCTCGC
CCCGCCTGAAGAAGGCTGGCAGCCTGAAGGATTTTCAACCGGAAAAAGCGGAAGAGCACAAAGCGCTGATATTTCCCAGC
TGACGGCAAATGAAGCGATTAAAACGAAACGCTTTTATTATTTATGGCTGATGCTTTTTATTAATGTTACGTGCGGAATC
GCCATCATATCAATCGCTTCACCGCTGGCGCAGGAAAGTGCGGGCATGTCCGCCGCCGCGGCCGCCGCGCTCGTCGGCGT
TTTGGGCGCATTTAACGGTTTAGGGCGCATCGGCTGGGCCTCTGTATCTGATTACATCGGACGGCCGAATACGTATACCG
TCTTTTTCGCCATACAGCTGATCGCCTTCCCGCTTTTGCCGTTCATTTCCGACAAGGCCGCCTTCTCTGTTTTGATGGCA
TTGATCTATACGTGCTATGGCGGAGGGTTTGCCGCAATTCCGGCTTATATCGGGGATTTGTTCGGAACAAAGCAGCTCGG
TGCGATCCACGGATACATTTTAACGGCTTGGGCGGCGGCAGGGCTTGCAGGCCCGATGTTCTCTTCTTGGGTACGCGATG
CAACAGGGAGCTACAGCCAAAGCCTGACGGTGTTTGCGGCACTGTTCGCCATCGCCCTGTTCATTTCGATATTCATTAGA
ACGGACATTAAACAGTTGCGGAAAAAAGCGGCGGTTCATGTCTCAAACTCGCTAAAAGGATGA

Upstream 100 bases:

>100_bases
ACTGCCCTTCTTCGCAGCAACTTCGGAAACCGCTTTCAAACAATCGCTCCCCGGCAGCCTTCTGTCTTTATTACAGCCTT
TTTCCACAGGGGGTTCTCAC

Downstream 100 bases:

>100_bases
TCTGCAGTATCCGCTGGAAAGGAGAGAAGGGAATGGGAAAAACAAAGCATCAAGGTCCGATGAAGCTGAATAAAAAGCCC
GCGCCAAAACTGTGGGCGTC

Product: hypothetical protein

Products: NA

Alternate protein names: OFA; Oxalate:formate antiport protein; Oxalate:formate exchange protein [H]

Number of amino acids: Translated: 420; Mature: 420

Protein sequence:

>420_residues
MKKAKNRWLIALCAVGIHLSIGSVYAWSVFTNPLAETFGWSLSQISLTFSIAILFLGLSAAFLGHFVEKHGPKKAGMLAA
LFFGAGVTFSGFAVQIGSLPLLYLFYGVFGGIGLGVGYITPVSSLVKWFPDRRGLATGLAIMGFGFAALISSPIMQKLIS
AVGIANTFFILGICYFLVMMLSSLYLAPPEEGWQPEGFSTGKSGRAQSADISQLTANEAIKTKRFYYLWLMLFINVTCGI
AIISIASPLAQESAGMSAAAAAALVGVLGAFNGLGRIGWASVSDYIGRPNTYTVFFAIQLIAFPLLPFISDKAAFSVLMA
LIYTCYGGGFAAIPAYIGDLFGTKQLGAIHGYILTAWAAAGLAGPMFSSWVRDATGSYSQSLTVFAALFAIALFISIFIR
TDIKQLRKKAAVHVSNSLKG

Sequences:

>Translated_420_residues
MKKAKNRWLIALCAVGIHLSIGSVYAWSVFTNPLAETFGWSLSQISLTFSIAILFLGLSAAFLGHFVEKHGPKKAGMLAA
LFFGAGVTFSGFAVQIGSLPLLYLFYGVFGGIGLGVGYITPVSSLVKWFPDRRGLATGLAIMGFGFAALISSPIMQKLIS
AVGIANTFFILGICYFLVMMLSSLYLAPPEEGWQPEGFSTGKSGRAQSADISQLTANEAIKTKRFYYLWLMLFINVTCGI
AIISIASPLAQESAGMSAAAAAALVGVLGAFNGLGRIGWASVSDYIGRPNTYTVFFAIQLIAFPLLPFISDKAAFSVLMA
LIYTCYGGGFAAIPAYIGDLFGTKQLGAIHGYILTAWAAAGLAGPMFSSWVRDATGSYSQSLTVFAALFAIALFISIFIR
TDIKQLRKKAAVHVSNSLKG
>Mature_420_residues
MKKAKNRWLIALCAVGIHLSIGSVYAWSVFTNPLAETFGWSLSQISLTFSIAILFLGLSAAFLGHFVEKHGPKKAGMLAA
LFFGAGVTFSGFAVQIGSLPLLYLFYGVFGGIGLGVGYITPVSSLVKWFPDRRGLATGLAIMGFGFAALISSPIMQKLIS
AVGIANTFFILGICYFLVMMLSSLYLAPPEEGWQPEGFSTGKSGRAQSADISQLTANEAIKTKRFYYLWLMLFINVTCGI
AIISIASPLAQESAGMSAAAAAALVGVLGAFNGLGRIGWASVSDYIGRPNTYTVFFAIQLIAFPLLPFISDKAAFSVLMA
LIYTCYGGGFAAIPAYIGDLFGTKQLGAIHGYILTAWAAAGLAGPMFSSWVRDATGSYSQSLTVFAALFAIALFISIFIR
TDIKQLRKKAAVHVSNSLKG

Specific function: Anion transporter that carries out the exchange of divalent oxalate with monovalent formate, the product of oxalate decarboxylation, at the plasma membrane, and in doing so catalyzes the vectorial portion of a proton-motive metabolic cycle that drives ATP

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. OFA (TC 2.A.1.11) family [H]

Homologues:

Organism=Homo sapiens, GI291621700, Length=437, Percent_Identity=25.858123569794, Blast_Score=77, Evalue=3e-14,
Organism=Escherichia coli, GI1789969, Length=368, Percent_Identity=26.3586956521739, Blast_Score=132, Evalue=3e-32,
Organism=Caenorhabditis elegans, GI193209150, Length=406, Percent_Identity=21.4285714285714, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI115532488, Length=450, Percent_Identity=20.6666666666667, Blast_Score=65, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI115532490, Length=450, Percent_Identity=20.6666666666667, Blast_Score=65, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR004741 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 44630; Mature: 44630

Theoretical pI: Translated: 9.94; Mature: 9.94

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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>Mature Secondary Structure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PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8636101; 9651403; 11919184; 11113128; 11274108; 11500368 [H]