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The map label for this gene is yqhB [H]

Identifier: 52787565

GI number: 52787565

Start: 3708258

End: 3709547

Strand: Direct

Name: yqhB [H]

Synonym: BLi03887

Alternate gene names: 52787565

Gene position: 3708258-3709547 (Clockwise)

Preceding gene: 52787562

Following gene: 52787566

Centisome position: 87.82

GC content: 45.04

Gene sequence:

>1290_bases
TTGAAGCTGATTGCAGTAGCAGGATTAATCGCATTTACGGGCTTTTTCGTCGCGGTCGAATTCGCCATCGTCAAAGTAAG
GCGGACAAAGATCGACCAATTGATCATTCAGAAAAAAAAGGGCGCTCTTGCCGCAAAAGAAGTGACCTCGCACCTTGACG
AATACTTGTCAGCCTGCCAGCTTGGAATCACCGTGACGGCATTGGGCTTGGGCTGGCTTGGTGAACCGACGATGCAGACC
TTGCTGCATCCCCTTTTCTCAAAAATCGGCTTGAACGAGTCGATTACACATATTCTTTCATTTTTGGCCGCTTTTTTATC
AGTTACTTATCTCAATGTTGTCGTCGGAGAGCTGGCGCCAAAAACGATCGCCATTCAAAAAGCGGAGACCGTTACGCTGC
TTTTTGCACAGCCGATGATCTGGTTTTATAGAATCATGTTTCCTTTTATATGGCTGCTCAATCATTCAGCCCGCATGATC
ACAAGTCTGTTCGGCCTGAAGCCGACCGGTGAACACGAATTGGCCTATTCGGAGGAAGAACTGCGAACGCTTTTATCTGA
AAGCTATCGAAGCGGGGAGATTAACCAAAATGAATTGAAATATGTAAACAATATTTTTAAATTCGACGAACGTACGGCAA
AAGAAATTATGGTGCCGCGCAATGAAATGACCGTCTTATCTCTTGACGACAGTTTAAAAAAAGCGAAGCAGCTTATCAAA
GAAACGAAGCACACCCGCTTCCCCGTCATGGAGGAAGACAAAGATCACATCACCGGAATGATCAATATAAAAGAACTGCT
GCTGGCGGAGCTTGCAGGGGAATTTTCTTTAGAAACAAAATCGCTAAAGCCATATATCCATCCGGTTATCCATGTGATTG
AAACGATTCCCGTCTACCAGCTGTTCGTCAAAATGCAGAAAGAGCATACACATATGGCGATTCTCGTAGATGAGTATGGC
GGAACATCGGGTCTTGTGACGGTTGAGGATATTGTCGAGGAAATCGTCGGCGACATTCGCGATGAATTCGATACTGAAGA
AGTATCTGCTGTTCAGAAACTCGAAGATGACCATTACATCCTAAACGCGAAAGTACTGGTCAGCGACGTAAACGACCTGC
TTGGAATTCATTTATCAGATGAGGAGATTGATACAATCGGCGGCTGGATGCTGACGCAGAATATTGAGAGCAAGCCCGGA
ACGACGATCGAAAGTGAAGGATACCGTTTTAAAGTAAAAGAAATGGACGGACATCGAATCGTTGCAGTTGAGGTTGAAAA
AACCGCTTAA

Upstream 100 bases:

>100_bases
ATGTTTGCCGCGCTGCGGCACGTGGTATGAAGCTAGTATGAGTTTTTCATAGAAAAGGAGGTGGCGCCTTCTTTACTGAG
AAGGCGGGGCATTGGAGTTA

Downstream 100 bases:

>100_bases
TCCCCCTTCTGTCGGATATTTCAGCCTCTCCCTGTCCGCTTTTCTCCCCAAAAACCATGTAAGGAAATCTGACATGTTCA
TCATGATATCTCCCTTTTGT

Product: YqhB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 429; Mature: 429

Protein sequence:

>429_residues
MKLIAVAGLIAFTGFFVAVEFAIVKVRRTKIDQLIIQKKKGALAAKEVTSHLDEYLSACQLGITVTALGLGWLGEPTMQT
LLHPLFSKIGLNESITHILSFLAAFLSVTYLNVVVGELAPKTIAIQKAETVTLLFAQPMIWFYRIMFPFIWLLNHSARMI
TSLFGLKPTGEHELAYSEEELRTLLSESYRSGEINQNELKYVNNIFKFDERTAKEIMVPRNEMTVLSLDDSLKKAKQLIK
ETKHTRFPVMEEDKDHITGMINIKELLLAELAGEFSLETKSLKPYIHPVIHVIETIPVYQLFVKMQKEHTHMAILVDEYG
GTSGLVTVEDIVEEIVGDIRDEFDTEEVSAVQKLEDDHYILNAKVLVSDVNDLLGIHLSDEEIDTIGGWMLTQNIESKPG
TTIESEGYRFKVKEMDGHRIVAVEVEKTA

Sequences:

>Translated_429_residues
MKLIAVAGLIAFTGFFVAVEFAIVKVRRTKIDQLIIQKKKGALAAKEVTSHLDEYLSACQLGITVTALGLGWLGEPTMQT
LLHPLFSKIGLNESITHILSFLAAFLSVTYLNVVVGELAPKTIAIQKAETVTLLFAQPMIWFYRIMFPFIWLLNHSARMI
TSLFGLKPTGEHELAYSEEELRTLLSESYRSGEINQNELKYVNNIFKFDERTAKEIMVPRNEMTVLSLDDSLKKAKQLIK
ETKHTRFPVMEEDKDHITGMINIKELLLAELAGEFSLETKSLKPYIHPVIHVIETIPVYQLFVKMQKEHTHMAILVDEYG
GTSGLVTVEDIVEEIVGDIRDEFDTEEVSAVQKLEDDHYILNAKVLVSDVNDLLGIHLSDEEIDTIGGWMLTQNIESKPG
TTIESEGYRFKVKEMDGHRIVAVEVEKTA
>Mature_429_residues
MKLIAVAGLIAFTGFFVAVEFAIVKVRRTKIDQLIIQKKKGALAAKEVTSHLDEYLSACQLGITVTALGLGWLGEPTMQT
LLHPLFSKIGLNESITHILSFLAAFLSVTYLNVVVGELAPKTIAIQKAETVTLLFAQPMIWFYRIMFPFIWLLNHSARMI
TSLFGLKPTGEHELAYSEEELRTLLSESYRSGEINQNELKYVNNIFKFDERTAKEIMVPRNEMTVLSLDDSLKKAKQLIK
ETKHTRFPVMEEDKDHITGMINIKELLLAELAGEFSLETKSLKPYIHPVIHVIETIPVYQLFVKMQKEHTHMAILVDEYG
GTSGLVTVEDIVEEIVGDIRDEFDTEEVSAVQKLEDDHYILNAKVLVSDVNDLLGIHLSDEEIDTIGGWMLTQNIESKPG
TTIESEGYRFKVKEMDGHRIVAVEVEKTA

Specific function: Unknown

COG id: COG1253

COG function: function code R; Hemolysins and related proteins containing CBS domains

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 CBS domains [H]

Homologues:

Organism=Homo sapiens, GI310128564, Length=393, Percent_Identity=49.3638676844784, Blast_Score=389, Evalue=1e-108,
Organism=Escherichia coli, GI1786879, Length=259, Percent_Identity=35.1351351351351, Blast_Score=142, Evalue=4e-35,
Organism=Escherichia coli, GI1790664, Length=426, Percent_Identity=24.1784037558685, Blast_Score=140, Evalue=2e-34,
Organism=Escherichia coli, GI145693175, Length=322, Percent_Identity=28.2608695652174, Blast_Score=121, Evalue=8e-29,
Organism=Escherichia coli, GI87082033, Length=265, Percent_Identity=26.4150943396226, Blast_Score=102, Evalue=5e-23,
Organism=Escherichia coli, GI1788119, Length=240, Percent_Identity=23.3333333333333, Blast_Score=68, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17539402, Length=254, Percent_Identity=27.9527559055118, Blast_Score=75, Evalue=9e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR000644
- InterPro:   IPR002550
- InterPro:   IPR005170 [H]

Pfam domain/function: PF00571 CBS; PF03471 CorC_HlyC; PF01595 DUF21 [H]

EC number: NA

Molecular weight: Translated: 48409; Mature: 48409

Theoretical pI: Translated: 5.06; Mature: 5.06

Prosite motif: PS00189 LIPOYL

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLIAVAGLIAFTGFFVAVEFAIVKVRRTKIDQLIIQKKKGALAAKEVTSHLDEYLSACQ
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
LGITVTALGLGWLGEPTMQTLLHPLFSKIGLNESITHILSFLAAFLSVTYLNVVVGELAP
HCHHHEEECCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCC
KTIAIQKAETVTLLFAQPMIWFYRIMFPFIWLLNHSARMITSLFGLKPTGEHELAYSEEE
CEEEEECCCEEEEEHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCCCHHH
LRTLLSESYRSGEINQNELKYVNNIFKFDERTAKEIMVPRNEMTVLSLDDSLKKAKQLIK
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCHHHHHHHHHHH
ETKHTRFPVMEEDKDHITGMINIKELLLAELAGEFSLETKSLKPYIHPVIHVIETIPVYQ
HHHCCCCCCCCCCCCHHEEEHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHH
LFVKMQKEHTHMAILVDEYGGTSGLVTVEDIVEEIVGDIRDEFDTEEVSAVQKLEDDHYI
HHHHHHHCCCEEEEEEECCCCCCCCEEHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCEE
LNAKVLVSDVNDLLGIHLSDEEIDTIGGWMLTQNIESKPGTTIESEGYRFKVKEMDGHRI
EEHHHHHHHHHHHHEEEECCCHHHHHCCEEEECCCCCCCCCEEECCCCEEEEEECCCCEE
VAVEVEKTA
EEEEEECCC
>Mature Secondary Structure
MKLIAVAGLIAFTGFFVAVEFAIVKVRRTKIDQLIIQKKKGALAAKEVTSHLDEYLSACQ
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
LGITVTALGLGWLGEPTMQTLLHPLFSKIGLNESITHILSFLAAFLSVTYLNVVVGELAP
HCHHHEEECCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCC
KTIAIQKAETVTLLFAQPMIWFYRIMFPFIWLLNHSARMITSLFGLKPTGEHELAYSEEE
CEEEEECCCEEEEEHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCCCHHH
LRTLLSESYRSGEINQNELKYVNNIFKFDERTAKEIMVPRNEMTVLSLDDSLKKAKQLIK
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCHHHHHHHHHHH
ETKHTRFPVMEEDKDHITGMINIKELLLAELAGEFSLETKSLKPYIHPVIHVIETIPVYQ
HHHCCCCCCCCCCCCHHEEEHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHH
LFVKMQKEHTHMAILVDEYGGTSGLVTVEDIVEEIVGDIRDEFDTEEVSAVQKLEDDHYI
HHHHHHHCCCEEEEEEECCCCCCCCEEHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCEE
LNAKVLVSDVNDLLGIHLSDEEIDTIGGWMLTQNIESKPGTTIESEGYRFKVKEMDGHRI
EEHHHHHHHHHHHHEEEECCCHHHHHCCEEEECCCCCCCCCEEECCCCEEEEEECCCCEE
VAVEVEKTA
EEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377 [H]