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The map label for this gene is clpP2 [H]

Identifier: 52787302

GI number: 52787302

Start: 3449148

End: 3449879

Strand: Reverse

Name: clpP2 [H]

Synonym: BLi03615

Alternate gene names: 52787302

Gene position: 3449879-3449148 (Counterclockwise)

Preceding gene: 52787303

Following gene: 52787301

Centisome position: 81.7

GC content: 44.54

Gene sequence:

>732_bases
ATGGCAACGGAACAGAAGAAGAAAAACAAGTATTGGAACATGAAGGTTCTGAATGATTCGACTGCTGAAATCACGCTTTA
CGGTTCTATTACTGGCGAAGGATGGTTTAGCGAGAGCTCGTCCAAGGCCTTTCAGGCTGAGTTGAAAAGTTTAGGTGACG
TGAGCTCTATTGATTTGTACATTAATTCGCCCGGTGGGGATGTTTTCGAGGGGCAGGCTATTCATTCGATGCTTCAGCGT
CACAAGGCAAAAATCAATGTCTATGTGGATGCACTGGCTGGAAGTATTGCTTCTGTCATTGCAATGGCCGGCGATAAAAT
TACGATGCCAAGTAACGCCATGATGATGATTCACAACCCATACATGGGGATGGTCGGGAATGCCGCGGAATTCCGGAAGG
CAGCCGATGATCTGGATAAGATTACTGAAAGTATCGTTTCCACATATCTTGCGAAAGCAGGAGACAAACTGGACGACGGG
ACTTTACGCCAGCTGCTGGATGAGGAAACCTGGCTCACCGCCGATGAAGCTTTAAATTATGGCTTGATCGATGAGGTTTC
AGAGTCAAAGGATGTAGCAGCCTGCATTGATCATCAGGTACTGGCACATTTTAAACATGTTCCAGGCAAAATTGTTGCTC
AATCTACTGCTGAAAGTCCGGCTGAAGAAACTAAGCCGGATGAATTACTAAAACAAAAGATCAATATGAAACTTGAACTC
TTAAATCTTTAA

Upstream 100 bases:

>100_bases
GATGAGCATTATGGAAACTTAAACCTTGTTCCCCTTTCAATTATGAAAGAGTATCAACTTAGCAAGGTCAAACGGTCTTC
AAATCGCCTGAAAGGGGGTG

Downstream 100 bases:

>100_bases
GGGTTCTTTTTTTATGCCACTATTAAGGAGGACAAGCATTTGAAACAGAAAAAGTTATTGAGACTTGATATTCAATTTTT
TGCCGGGGGCGGAATGTCCA

Product: hypothetical protein

Products: NA

Alternate protein names: Endopeptidase Clp [H]

Number of amino acids: Translated: 243; Mature: 242

Protein sequence:

>243_residues
MATEQKKKNKYWNMKVLNDSTAEITLYGSITGEGWFSESSSKAFQAELKSLGDVSSIDLYINSPGGDVFEGQAIHSMLQR
HKAKINVYVDALAGSIASVIAMAGDKITMPSNAMMMIHNPYMGMVGNAAEFRKAADDLDKITESIVSTYLAKAGDKLDDG
TLRQLLDEETWLTADEALNYGLIDEVSESKDVAACIDHQVLAHFKHVPGKIVAQSTAESPAEETKPDELLKQKINMKLEL
LNL

Sequences:

>Translated_243_residues
MATEQKKKNKYWNMKVLNDSTAEITLYGSITGEGWFSESSSKAFQAELKSLGDVSSIDLYINSPGGDVFEGQAIHSMLQR
HKAKINVYVDALAGSIASVIAMAGDKITMPSNAMMMIHNPYMGMVGNAAEFRKAADDLDKITESIVSTYLAKAGDKLDDG
TLRQLLDEETWLTADEALNYGLIDEVSESKDVAACIDHQVLAHFKHVPGKIVAQSTAESPAEETKPDELLKQKINMKLEL
LNL
>Mature_242_residues
ATEQKKKNKYWNMKVLNDSTAEITLYGSITGEGWFSESSSKAFQAELKSLGDVSSIDLYINSPGGDVFEGQAIHSMLQRH
KAKINVYVDALAGSIASVIAMAGDKITMPSNAMMMIHNPYMGMVGNAAEFRKAADDLDKITESIVSTYLAKAGDKLDDGT
LRQLLDEETWLTADEALNYGLIDEVSESKDVAACIDHQVLAHFKHVPGKIVAQSTAESPAEETKPDELLKQKINMKLELL
NL

Specific function: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins [H]

COG id: COG0740

COG function: function code OU; Protease subunit of ATP-dependent Clp proteases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S14 family [H]

Homologues:

Organism=Caenorhabditis elegans, GI17538017, Length=133, Percent_Identity=30.8270676691729, Blast_Score=75, Evalue=4e-14,
Organism=Drosophila melanogaster, GI20129427, Length=135, Percent_Identity=33.3333333333333, Blast_Score=69, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001907
- InterPro:   IPR018215 [H]

Pfam domain/function: PF00574 CLP_protease [H]

EC number: =3.4.21.92 [H]

Molecular weight: Translated: 26604; Mature: 26472

Theoretical pI: Translated: 4.70; Mature: 4.70

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATEQKKKNKYWNMKVLNDSTAEITLYGSITGEGWFSESSSKAFQAELKSLGDVSSIDLY
CCCCCCCCCCCEEEEEECCCCEEEEEEEEECCCCCCCCCCHHHHHHHHHHCCCCCEEEEE
INSPGGDVFEGQAIHSMLQRHKAKINVYVDALAGSIASVIAMAGDKITMPSNAMMMIHNP
EECCCCCCCCCHHHHHHHHHHHHHEEEEHHHHHHHHHHHHHHCCCCEECCCCCEEEEECC
YMGMVGNAAEFRKAADDLDKITESIVSTYLAKAGDKLDDGTLRQLLDEETWLTADEALNY
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCHHHCCCHHHHCCC
GLIDEVSESKDVAACIDHQVLAHFKHVPGKIVAQSTAESPAEETKPDELLKQKINMKLEL
CCHHHHCCCCHHHHHHHHHHHHHHHCCCCCEEECCCCCCCCCCCCHHHHHHHHHCCEEEE
LNL
ECC
>Mature Secondary Structure 
ATEQKKKNKYWNMKVLNDSTAEITLYGSITGEGWFSESSSKAFQAELKSLGDVSSIDLY
CCCCCCCCCCEEEEEECCCCEEEEEEEEECCCCCCCCCCHHHHHHHHHHCCCCCEEEEE
INSPGGDVFEGQAIHSMLQRHKAKINVYVDALAGSIASVIAMAGDKITMPSNAMMMIHNP
EECCCCCCCCCHHHHHHHHHHHHHEEEEHHHHHHHHHHHHHHCCCCEECCCCCEEEEECC
YMGMVGNAAEFRKAADDLDKITESIVSTYLAKAGDKLDDGTLRQLLDEETWLTADEALNY
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCHHHCCCHHHHCCC
GLIDEVSESKDVAACIDHQVLAHFKHVPGKIVAQSTAESPAEETKPDELLKQKINMKLEL
CCHHHHCCCCHHHHHHHHHHHHHHHCCCCCEEECCCCCCCCCCCCHHHHHHHHHCCEEEE
LNL
ECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA